Potential rockfalls and analysis of slope dynamics in the palatine archaeological area (Rome, Italy)

The Palatine Hill is among the main archaeological sites of Roman antiquity. Today, this place requires continuous care for its safeguarding and conservation. Among the main problems, slope instabilities threaten the southwestern border of the hill flanked by the Velabrum Valley, as also testified by historical documents. The upper part of the investigated slope is characterized by Middle Pleistocene red-brownish tuffs known as "Tufo Lionato". The rock mass is affected by two jointing belts featuring the slope edge and its internal portion with different joint frequency and distribution. The analysis of the geometric relationship between the joint systems and the slope attitude evidenced possible planar sliding and toppling failure mechanisms on the exposed tuff cliffs. Potential rock block failures threatening the local cultural heritage were contrasted with preliminary works for site remediation. In addition, stress-strain numerical modelling verified the hypothesis of a tensile origin for the jointing belts, suggested by fracture characteristics and orientation. A first modelling was limited to the southwestern edge of the Palatine Hill and analysed the present stress-strain condition of the slope, proving the inconsistency with the observed deformation. A second modelling was extended to the Palatine-Velabrum slope-to-valley system to consider the role played by the geomorphological evolution of the area on the local slope dynamics during the late Pleistocene-Holocene. Results demonstrate how original conditions of slope instability, deformation and retreat along the Palatine western edge were determined by deep valley incision, and controlled by deformability contrasts within the slope. Slope instability influenced the site occupation and development during the Roman civilization, as also indicated by the remnants of retaining walls of different ages at the slope base

Centrifuge rolling test for ore liquefaction analysis

To study the development of liquefaction in ore cargo, a new Rolling Test has been designed to support similar stresses than those observed in a vessel. It can be used in an 80×g macrogravity field in the 5.5m radius Ifsttar geo-centrifuge. Its main characteristics are presented

31P-NMR spectroscopy of phosphate compartmentation during ischaemia in hearts protected by cardioplegic treatment.

Four tissue compartments, differing in proton and inorganic phosphate concentration, were resolved by 31P-NMR spectroscopy in samples from dog hearts after cardioplegic treatment with HTK solution. Inversion of the physiological cytoplasmic-mitochondrial pH gradient was observed. The considerable ensuing acidosis of the matrix is discussed with regard to a possible delocalisation of ferrous ions

SFTA2 - a novel secretory peptide highly expressed in the lung - is modulated by lipopolysaccharide but not hyperoxia

Tissue-specific transcripts are likely to be of importance for the corresponding organ. While attempting to define the specific transcriptome of the human lung, we identified the transcript of a yet uncharacterized protein, SFTA2. In silico analyses, biochemical methods, fluorescence imaging and animal challenge experiments were employed to characterize SFTA2. Human SFTA2 is located on Chr. 6p21.33, a disease-susceptibility locus for diffuse panbronchiolitis. RT-PCR verified the abundance of SFTA2-specific transcripts in human and mouse lung. SFTA2 is synthesized as a hydrophilic precursor releasing a 59 amino acid mature peptide after cleavage of an N-terminal secretory signal. SFTA2 has no recognizable homology to other proteins while orthologues are present in all mammals. SFTA2 is a glycosylated protein and specifically expressed in nonciliated bronchiolar epithelium and type II pneumocytes. In accordance with other hydrophilic surfactant proteins, SFTA2 did not colocalize with lamellar bodies but colocalized with golgin97 and clathrin-labelled vesicles, suggesting a classical secretory pathway for its expression and secretion. In the mouse lung, Sfta2 was significantly downregulated after induction of an inflammatory reaction by intratracheal lipopolysaccharides paralleling surfactant proteins B and C but not D. Hyperoxia, however, did not alter SFTA2 mRNA levels. We have characterized SFTA2 and present it as a novel unique secretory peptide highly expressed in the lung

Diffractometer‐Control Software For Bragg‐Rod Measurements

We present Generalized Diffractometer Control (gdc), a diffractometer‐control software package developed specifically for high‐precision measurements of Bragg rods; we discuss its features and analyze its performance in data collection. gdc, implemented at several APS beamlines, controls a six‐circle diffractometer in either Eulerian or kappa geometry, yet does not assume a mechanically ideal diffractometer; instead, the measured directions of the diffractometer axes (and the direction of the incident beam) are input parameters. The Labview‐based program features a graphical interface, making it straightforward to find all the commands and operations. Other features include optimized scans along Bragg rods, straightforward background subtraction, and extensive sets of pseudomotors. © 2004 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87660/2/1221_1.pd

Prevalence of pelvic floor disorders in women with suspected gynecological malignancy: a survey-based study

Understanding of pelvic floor disorders among women with gynecological cancer is limited. The objective of this study was to describe the prevalence of pelvic floor disorders in women with suspected gynecological malignancy before surgery

Establishing spin-network topologies by repeated projective measurements

It has been recently shown that in quantum systems, the complex time evolution typical of many-bodied coupled networks can be transformed into a simple, relaxation-like dynamics, by relying on periodic dephasings of the off-diagonal density matrix elements. This represents a case of "quantum Zeno effects", where unitary evolutions are inhibited by projective measurements. We present here a novel exploitation of these effects, by showing that a relaxation-like behaviour is endowed to the polarization transfers occurring within a N-spin coupled network. Experimental implementations and coupling constant determinations for complex spin-coupling topologies, are thus demonstrated within the field of liquid-state nuclear magnetic resonance (NMR).Comment: 4+ pages, 3 figure