El poblamiento de la Comarca de Alcántara (Cáceres) durante la Edad del Hierro

Sin resume

Medellín 1991. La ladera norte del Cerro del Castillo

Medellín es un importante oppidum Orientalizante de la Península Ibérica de extensión y cronología comparables a las poblaciones turdetanas. Formaba parte de la Cultura Tartésica y su población se concentraba hacia el Cerro del Castillo para controlar la rica vega y el paso del río hacia las áreas pacidentales, lo que explica su papel como centro de las Vegas del Guadiana. Tras la Cultura Tartésica, evolucionó hacia la “Cultura de los Oppida” de Extremadura, para la que ofrece una secuencia clave, ya que mantuvo contactos con el área turdetana hasta su temprana romanización, siendo el principal apoyo de Roma hasta la fundación de Emerita Augusta.Medellín is an important oppidum of the Orientalizing Period in Iberia; its extension and chronology are similar to other turdetanian settlements. It took part of the Tartesian Culture. The settlemet was concentrated at the Cerro del Castillo as the center of the very rich territory of Vegas del Guadiana in order to control the passage of the river to the rich northwestern areas of Iberia. After the Tartesian Culture, it evolved towards a so-called “Oppida-Culture from Extremadura“. It offers a very important sequence because it had contacts with the turdetanian area untill its romanisation, when it played a important role before the foundation of Augusta Emerita

Differences in perceived popularity and social preference between bullying roles and class norms

The aim of this study was to examine differences in perceived popularity and social preference of bullying roles and class norms. In total, 1,339 students (48% girls) participated: 674 primary school (M = 10.41 years, SD = 0.49) and 685 secondary school students (M = 12.67 years, SD = 0.80). Peer nominations and perceptions of class norms were collected. The results showed the highest perceived popularity among aggressors and defenders, except in anti-bullying primary school classes, where aggressors had low levels of popularity. In pro-bullying secondary school classes school, female victims had the lowest popularity levels. These findings suggest that class norms and personal variables as gender and school levels are important to understand bullying roles. Practical implications are discussed to guide teachers and practitioners according to the importance to adapt antibullying programs to the characteristics of the group in each school level and gender

A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats

The effects of cocoa feeding against N-nitrosodiethylamine (DEN)-induced liver injury were studied in rats. Animals were divided into five groups. Groups 1 and 2 were fed with standard and cocoa-diet, respectively. Groups 3 and 4 were injected with DEN at 2 and 4 weeks, and fed with standard and cocoa-diet, respectively. Group 5 was treated with DEN, received the standard diet for 4 weeks and then it was replaced by the cocoa-diet. DEN-induced hepatic damage caused a significant increase in damage markers, as well as a decrease in the hepatic glutathione, diminished levels of p-ERK and enhanced protein carbonyl content, caspase-3 activity and values of p-AKT and p-JNK. The cocoa-rich diet prevented the reduction of hepatic glutathione concentration and catalase and GPx activities in DEN-injected rats, as well as diminished protein carbonyl content, caspase-3 activity, p-AKT and p-JNK levels, and increased GST activity. However, cocoa administration did not abrogate the DEN-induced body weight loss and the increased levels of hepatic-specific enzymes and LDH. These results suggested that cocoa-rich diet attenuates the DEN-induced liver injury. © 2009 Elsevier Ltd. All rights reserved.This work was supported by the grants 200870I198, AGL2004-302, AGL2007-64042 and CSD2007-00063 from the Spanish Ministry of Science and Innovation. A.B. Granado-Serrano is a predoctoral fellow of the Spanish Ministry of Science and Education.Peer Reviewe

Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study

Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile, 3Department of Kinesiology, Faculty of Health Sciences, Universidad Católica del Maule, Talca, Chile, 4Facultad de Psicología, Universidad de Talca, Talca, Chile, 5Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile, 6Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.This study was supported by the following grants: Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1120528 (JLF), Fondo Central de Investigación, Universidad de Chile ENL025/16 (JLF).Several studies have shown that a single exposure to stress may improve or impair learning and memory processes, depending on the timing in which the stress event occurs with relation to the acquisition phase. However, to date there is no information about the molecular changes that occur at the synapse during the stress-induced memory modification and after a recovery period. In particular, there are no studies that have evaluated—at the same time—the temporality of stress and stress recovery period in hippocampal short-term memory and the effects on dendritic spine morphology, along with variations in N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits. The aim of our study was to take a multidimensional approach to investigate concomitant behavioral, morphological and molecular changes induced by a single restraint stress exposure (2.5 h) and a recovery period of 6 and 24 h in rats. We found that acute stress elicited a reduced preference to explore an object placed in a novel position (a hippocampal-dependent task). These changes were accompanied by increased activity of LIM kinase I (LIMK; an actin-remodeling protein) and increased levels of NR2A subunits of NMDA receptors. After 6 h of recovery from stress, rats showed similar preference to explore an object placed in a novel or familiar position, but density of immature spines increased in secondary CA1 apical dendrites, along with a transient rise in GluA2 AMPA receptor subunits. After 24 h of recovery from stress, the animals showed a preference to explore an object placed in a novel position, which was accompanied by a normalization of NMDA and AMPA receptor subunits to control values. Our data suggest that acute stress produces reversible molecular and behavioral changes 24 h after stress, allowing a full reestablishment of hippocampal-related memory. Further studies need to be conducted to deepen our understanding of these changes and their reciprocal interactions.Adaptive stress responses are a promising avenue to develop interventions aiming at restoring hippocampal function impaired by repetitive stress exposure. © 2018 Aguayo, Tejos-Bravo, Díaz-Véliz, Pacheco, García-Rojo, Corrales, Olave, Aliaga, Ulloa, Avalos, Román-Albasini, Rojas and Fiedler.https://www.frontiersin.org/articles/10.3389/fnmol.2018.00283/ful

Visualizing Extracurricular Student Teams Learning at Tu/e Innovation Space with CDIO Syllabus

This paper's purpose is to present the findings of exploratory research performed at TU/e innovation Space to gain a better understanding of what students learn in extracurricular student teams. Having a better understanding of student learning can help us make such learning more visible, which has a positive impact on students' development of professional identity and employability. The scope of this study includes interviews with five alumni from student teams and an analysis of its outcomes. The results of the interviews' analysis showed that students recognized that they experienced learning gains because of their participation in student teams. However, the process of describing the learning gains in a detailed way is not easy for them, showing that their extracurricular efforts did not make these learning gains explicit. Students reported learning gains associated with personal and professional skills (CDIO syllabus section 2) and interpersonal skills, collaboration, teamwork, and communication (CDIO syllabus section 3). Peer interactions and learning by doing were the most relevant media that promoted those learning gains. Finally, we conclude that additional methods such as observations during teamwork can help understand the mechanisms that facilitate learning

Friendship selection and influence processes for popularity in early and mid-adolescents

Introduction This study examined the effect of popularity levels on friendship selection and friends' influence on popularity levels in early and mid-adolescence. Methods Participants were 4205 Spanish adolescents (M-age = 13.1 years at Wave 1; 48% girls) belonging to 160 classrooms in two waves. Adolescents were asked about their friendships and the popularity of their classmates. Results Longitudinal social network analyses showed that adolescents preferred similarly popular peers as friends. High popular classmates were more attractive as friends, particularly in early adolescence. Popular adolescents were more selective in their friendship nominations and adolescents with popular friends became more popular over time. These two effects were only significant in mid-adolescents, although comparative analyses showed a similar tendency at both age groups. Conclusions This study highlights the importance of popularity levels in adolescents' friendship selection and suggests that popularity, at the individual and group level, plays a relevant role in social development. Implications adapted to the different selection and influence processes in early and mid-adolescence are discussed

Pathogenic A. salmonicida from human patients

The bacterium Aeromonas salmonicida is known since long time as a major fish pathogen unable to grow at 37 °C. However, some cases of human infection by putative mesophilic A. salmonicida have been reported. The goal of the present study is to examine two clinical cases of human infection by A. salmonicida in Spain and to investigate the pathogenicity in mammals of selected mesophilic A. salmonicida strains. An evaluation of the pathogenicity in a mouse model of clinical and environmental A. salmonicida strains was performed. The genomes of the strains were sequenced and analyzed in order to find the virulence determinants of these strains. The experimental infection in mice showed a gradient in the virulence of these strains and that some of them can cause necrotizing fasciitis and tissue damage in the liver. In addition to demonstrating significant genomic diversity among the strains studied, bioinformatics analyses permitted also to shed light on crucial elements for the virulence of the strains, like the presence of a type III secretion system in the one that caused the highest mortality in the experimental infection. Clinicians and microbiologists should consider these results for the inclusion of A. salmonicida in diagnosis tests since it is now clear that some mesophilic strains are also pathogens for humans

Ability emotional intelligence in young people and older adults with and without depressive symptoms, considering gender and educational level

We thank Professors Laura Ros, Rigoberto López, Concha Fabeiro, Diosina Lozano and David Igual for their help in the selection of the sample. Our thanks also go to Dr. Carlos de Cabo for his assistance with the translation of the manuscript.Supplemental information for this article can be found online at http://dx.doi.org/10.7717/ peerj.6595#supplemental-information.Background There is little research on differences in Emotional Intelligence (EI) ability at different stages of adult development. The few published studies tend not to use older adult samples. Previous studies on EI ability and age have shown contradictory results. Our main objective was to evaluate results in EI ability across different stages of adult development, taking into account gender, depressive symptoms, and educational level. Methods We interviewed 166 participants (108 women), 66 of whom were aged 18–30 years, 53 aged 31–60 years, and 40 aged 61–76 years. All were either working or enrolled in colleges at the time of the study. The assessment tools used were the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT), a test that assesses performance-based EI, and the Centre for Epidemiologic Studies-Depression (CES-D) scale, a tool to evaluate depressive symptoms. Results Young people, women, and participants with a higher educational level achieved higher scores on the MSCEIT. Additionally, depressive symptomatology was only partially associated with the MSCEIT (i.e., with the using emotions branch). However, a subsequent joint analysis of the independent effects of variables age, gender, educational level, and depressive symptomatology and their interactions on MSCEIT total suggests that only educational level and depressive symptomatology were associated with EI ability, with the direct relationship between age and gender with MSCEIT disappearing. Additionally, our study indicated an interaction effect between age and depressive symptoms, showing that participants in age cohorts 18–30 and 31–60 and without depressive symptoms have a higher EI ability. Discussion Our study suggests that the direct effects of age and gender on EI ability across adult development, using a wide age range, can change or disappear when effects of educational level and depressive symptomatology, and their interactions, are controlled for. Our results also suggest that EI ability is a protective factor against depression in some age cohorts. This novel aspect of our study does not appear in the previous literature. However, prospective studies are needed to verify these findings and examine whether other psychological variables could determine the relations between age, gender and EI ability across adult development.This work was supported by a project grant awarded to Pablo Fernández-Berrocal from the Spanish Ministry of Economy, Industry and Competitiveness (PSI2017-84170-R). This work was also supported by the project Innovation and Development Agency of Andalusia, Spain (grant number SEJ-07325) and the Ministry of Economy, Industry and Competitiveness (grant number PSI2017-84170-R). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript