Application of Things: A Step beyond Web of Things

Internet of Things has achieved a great expectation in the last few years, largely due to possibilities in the field of the interaction between user and environment. This interaction allows users to get involved in their environments, managing at all times each item that surrounds them. Specially, because of complex services delivered by surrounding item, increasingly it is necessary to help users to choose what services are offered and what are theirs functionalities. Is this paper, is presented a new approach to the human-items interaction by using the concept of Internet of Things. In this way, the user can not only run the different applications offers by smart-things, but to share theirs results through many social networks and allows the remote execution of services provided by the own user and his/her social environment. Furthermore, a structure will be defined to assure the best user comfort when information sharing between the device and the environments was needed.Ministerio de Ciencia e Innovación TIN2009-14378-C02-0

Electric dipole polarizability of 40^{40}Ca

The electric dipole strength distribution in $^{40}$Ca between 5 and 25 MeV has been determined at RCNP, Osaka, from proton inelastic scattering experiments at very forward angles. Combined with total photoabsorption data at higher excitation energy, this enables an extraction of the electric dipole polarizability $\alpha_\mathrm{D}$($^{40}$Ca) = 1.92(17) fm$^3$. Together with the measured $\alpha_{\rm D}$ in $^{48}$Ca, it provides a stringent test of modern theoretical approaches, including coupled cluster calculations with chiral effective field theory interactions and state-of-the art energy density functionals. The emerging picture is that for this medium-mass region dipole polarizabilities are well described theoretically, with important constraints for the neutron skin in $^{48}$Ca and related equation of state quantities.Comment: 6 pages, 3 figure

A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel–Palade body exocytosis in endothelial cells

Endothelial cells respond to blood vessel injury by the acute release of the procoagulant von Willebrand factor, which is stored in unique secretory granules called Weibel-Palade bodies (WPBs). Stimulated WPB exocytosis critically depends on their proper recruitment to the plasma membrane, but factors involved in WPB-plasma membrane tethering are not known. Here we identify Munc13-4, a protein mutated in familial hemophagocytic lymphohistiocytosis 3, as a WPB-tethering factor. Munc13-4 promotes histamine-evoked WPB exocytosis and is present on WPBs, and secretagogue stimulation triggers an increased recruitment of Munc13-4 to WPBs and a clustering of Munc13-4 at sites of WPB-plasma membrane contact. We also identify the S100A10 subunit of the annexin A2 (AnxA2)-S100A10 protein complex as a novel Munc13-4 interactor and show that AnxA2-S100A10 participates in recruiting Munc13-4 to WPB fusion sites. These findings indicate that Munc13-4 supports acute WPB exocytosis by tethering WPBs to the plasma membrane via AnxA2-S100A10

Mid‐ to late Holocene environmental changes and human‐environment interactions in the surroundings of La Silla del Papa, SW Spain

International audienceIn southern Iberia, the surroundings of the Strait of Gibraltar are known as a crossroad for population movements, cultural exchanges, and trade from Late Prehistory to modern times. However, questions remain about the impact of this historical development on the environment. The settlement of La Silla del Papa, an important hillfort in southern Andalusia (Cádiz), was occupied during the entire Iron Age, replaced by the coastal town Baelo Claudia during Roman times, and reoccupied during Early Medieval times. As such, La Silla del Papa and its territory represent an ideal location for long-term studies on human-environment interactions. Within the framework of the interdisciplinary project "Archeostraits," geoarchaeological investigations in the surroundings of La Silla del Papa aimed at constraining ecological conditions and human-environment interactions during the This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes

PANDORA project: photo-nuclear reactions below A=60A=60

Photo-nuclear reactions of light nuclei below a mass of $A=60$ are studied experimentally and theoretically by the PANDORA (Photo-Absorption of Nuclei and Decay Observation for Reactions in Astrophysics) project. Two experimental methods, virtual-photon excitation by proton scattering and real-photo absorption by a high-brilliance gamma-ray beam produced by laser Compton scattering, will be applied to measure the photo-absorption cross sections and the decay branching ratio of each decay channel as a function of the photon energy. Several nuclear models, e.g. anti-symmetrized molecular dynamics, mean-field type models, a large-scale shell model, and ab initio models, will be employed to predict the photo-nuclear reactions. The uncertainty in the model predictions will be evaluated from the discrepancies between the model predictions and the experimental data. The data and the predictions will be implemented in a general reaction calculation code TALYS . The results will be applied to the simulation of the photo-disintegration process of ultra-high-energy cosmic rays in inter-galactic propagation

PANDORA project: photo-nuclear reactions below A=60A=60

Photo-nuclear reactions of light nuclei below a mass of $A=60$ are studied experimentally and theoretically by the PANDORA (Photo-Absorption of Nuclei and Decay Observation for Reactions in Astrophysics) project. Two experimental methods, virtual-photon excitation by proton scattering and real-photo absorption by a high-brilliance gamma-ray beam produced by laser Compton scattering, will be applied to measure the photo-absorption cross sections and the decay branching ratio of each decay channel as a function of the photon energy. Several nuclear models, e.g. anti-symmetrized molecular dynamics, mean-field type models, a large-scale shell model, and ab initio models, will be employed to predict the photo-nuclear reactions. The uncertainty in the model predictions will be evaluated from the discrepancies between the model predictions and the experimental data. The data and the predictions will be implemented in a general reaction calculation code TALYS . The results will be applied to the simulation of the photo-disintegration process of ultra-high-energy cosmic rays in inter-galactic propagation