2,168 research outputs found

    Influência da intermitência do tempo de irrigação na cultura da videira festival irrigada por gotejamento, no vale do Submédio são Francisco.

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    Portando, esse trabalho teve como objetivo adequar manejos de irrigação que possibilite maiores produções da cultura com a mesma quantidade de água requerida

    Decreased Survival in African Patients with Triple Negative Breast Cancer

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    Abstract Introduction: Triple Negative Breast Carcinomas (TNBC) are more prevalent in younger women especially those with African Ancestry, in whom the disease appears to be more aggressive. Since there are no data on Africans living in continental Europe, we sought to analyse a sample of African women from a European country and determine if, like African Americans, they have more aggressive tumor biology and poorer outcomes. Methods: We performed a retrospective review of TNBC to compare clinical and pathological features and survival between African and non-African patients. All women presented with breast cancer (BC), between 2005 and 2014, to a single general hospital, in Portugal. Results: A total of 144 (9.3% of the whole sample) TNBC patients were identified and amongst these, 17 were African (12%). African patients were not significantly younger than non-African patients (median age of 60 years vs 57.2 years, respectively, p=0.59). Regarding tumor size, nodal status and histologic grade at presentation, these variables were very similar between the two cohorts. Nevertheless, the prevalence of initially metastatic BC was significantly higher among the African population (41.2% vs 11%, p<0,005) and the outcome was worse for these patients (median survival: 62 vs 15 months, p<0.005). Conclusions: Our study demonstrated that African patients more frequently presented with late stage disease and worse survival outcome than the non-African population. These findings may be explained by more aggressive tumor biology.info:eu-repo/semantics/publishedVersio

    What about vaginal extraction of the kidney? results of an online survey

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    PURPOSE: We aimed to characterize surgeons opinion about the vaginal extraction of the kidney after transperitoneal laparoscopic nephrectomy. Matherial and Methods: A 9-item questionnaire was published online (Survey Monkey TM) and publicized via email to a multidisciplinary pool of surgeons in Portugal. Data was collected and statistical analysis was performed using IBM SPSS Statistics, Version 21.0. RESULTS: Three hundred and fifty nine inquiries were sent, 154 surgeons completed the questionnaires (response rate of 43.0%). Fifty five point eight percent of the participants would choose the transvaginal approach for themselves or for a close relative. The most stated arguments were a better cosmesis (29.0%) expectancy of lower post operative pain (26.0%) and lower rate of incisional hernias (23.0%). Defenders of the transabdominal procedure justified with an expectancy of lower complication rate (39%), namely impairment of sexual function and fertility (22%). The female gender and the familiarity with transvaginal surgery were the stronger predictors of the option for this approach (70.6% vs 48.5%; p=0,016 and 85.3% vs 46.6%; p <0.001 respectively). CONCLUSIONS: Contrasting with similar surveys published on transvaginal NOTES, the vaginal specimen extraction after conventional laparoscopic nephrectomy was fairly accepted by the inquired surgeons.info:eu-repo/semantics/publishedVersio

    Performance of processing tomatoes under different supply levels of crop evapotranspiration.

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    This study was installed to evaluate productive performance of two processing tomato hybrids submitted to five water depths under drip irrigation system. Five levels of crop evapotranspiration (ETc) replacement (60%, 100%, 140%, 180% and 220%) and two tomato hybrids (BRS Sena and H 9992) were tested

    Emulsions vs excipient emulsions as -tocopherol delivery systems: Formulation optimization and behaviour under in vitro digestion

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    Oil-in-water emulsions (EM) have been extensively used for the encapsulation of lipophilic bioactive compounds and posterior incorporation into food matrices to obtain functional foods. Conversely, novel excipient oil-in-water emulsions (EXC) present identical composition and structure as EM, albeit are not bioactive by themselves since no bioactive compound is encapsulated. Instead, EXC aims at improving the bioavailability of foods natural bioactive compounds upon co-ingestion with nutrient-rich foods. In this work, EM and EXC were produced and their stability and functionality as delivery systems for -tocopherol compared. Emulsions were formulated with corn oil and lecithin, and their composition was optimized using experimental designs. Formulations produced with 3 % lecithin and 5 % oil attained smallest particles sizes with the lowest polydispersity index of all tested formulations and remained stable up to 60 days. Encapsulation of -tocopherol did not have a significative impact on the structural properties of the particles produced with the same composition. -tocopherol stability during in vitro digestion was superior in EM regardless the processing methodology (EM stability < 50 %, EXC stability < 29 %), indicating that EM offered greater protection against the digestive environment. -tocopherols bioaccessibility was significantly increased when encapsulated or when digested with added excipient emulsions (8292 % and 8790 % for EM and EXC, respectively). In conclusion, EM were more efficient vehicles for the selected bioactive compound, however, the good results obtained with EXC imply that excipient emulsions have a great potential for applications on foods to improve their natural bioactive compounds bioavailability without the need of further processing.info:eu-repo/semantics/publishedVersio

    Improving the design of nozzles used in zamak high-pressure die-casting process

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    The injection of light alloys is an activity that requires a high effort on the part of Engineering to maintain its competitiveness. Due to the temperatures used, the wear of the components connected to this manufacturing process is quite intense, requiring a constant updating effort. This work was developed with a view to solving problems related to the excessive wear of injection nozzles used in the die casting process, and corresponding electrical resistances, with a view to increase its lifetime and improve the competitiveness of the process in the injection of low-cost parts in zamak for the automotive industry. To study and solve the problems of premature wear of the injection nozzles, the action-research method was used, which, through several iterations, allowed to arrive at an improved design of the nozzle, as well as the corresponding electrical resistance, thus increasing the life span of these components, also improving safety around the process and generating knowledge that can be transferable to other similar situations.The authors would like to thank Mr. Mário Cardoso from FicoCables, Lda. for his continuous support, proving interesting challenges for applied research. Authors would like to thank Ing. Fátima Andrade due to her help in preparing the samples and collecting images in the optical microscope. Authors would also thank INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial, Porto, Portugal, due to its continuous support.info:eu-repo/semantics/publishedVersio

    Diagnostic pro-innovation methodology for socio-environmental responsible organizations

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    Organizational managers seek to align their strategies in order to keep their business in the competitive environment. This qualitative research is based on the Theory of Planned Behavior, the concepts of innovation and other related required. The expectation of this task is to interpret the client\u27s perception as a driver for the innovation required in the operating system of supermarkets in the city of Porto Velho, capital of Rond&ocirc;nia State, Brazil. It has as main objective to develop a valid methodology to the monitoring of change required in the face of the behavior of the consumer. For this, specific objectives are required: Identify the elements of innovation that promote changes in the behavior of the consumer (1), describe the innovations perceived by the consumers in organizations socially and environmentally responsible (2), and develop a methodology to diagnose the organizational innovation (3). It was adopted the Case Study Method, with bibliographic research, focus groups, questionnaires, data tabulation, analysis and critique of the content and preparation of the results obtained. As an additional instrument was used the Table Likert in the measurement of five options, in order to understand the satisfaction of the respondent. The research shows that supermarkets satisfy the purchase item, but that the organization needs to focus on four elements to improve their performance; when considering these elements forward the strategic functional activities, it is possible to identify the challenges of innovation focused on the excellence of the organization\u27s operating system; the methodology proposes the performing of diagnostic processes that drive the innovation processes for an efficient and effective strategic performance in organizations dedicated to the customer. It is expected to recognize the consumer\u27s perception and, based on thi parameters, guide the processes of innovation strategically. This study is a contribution to organizations seeking competitive advantage through continuous innovation focused on the customer

    Astrometry of the main satellites of Uranus: 18 years of observations

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    We determine accurate positions of the main satellites of Uranus: Miranda, Ariel, Umbriel, Titania, and Oberon. Positions of Uranus, as derived from those of these satellites, are also determined. The observational period spans from 1992 to 2011. All runs were made at the Pico dos Dias Observatory, Brazil. We used the software called Platform for Reduction of Astronomical Images Automatically (PRAIA) to minimise (digital coronography) the influence of the scattered light of Uranus on the astrometric measurements and to determine accurate positions of the main satellites. The positions of Uranus were then indirectly determined by computing the mean differences between the observed and ephemeris positions of these satellites. A series of numerical filters was applied to filter out spurious data. These filters are mostly based on the comparison between the positions of Oberon with those of the other satellites and on the offsets as given by the differences between the observed and ephemeris positions of all satellites. We have, for the overall offsets of the five satellites, -29 (+/-63) mas in right ascension and -27 (+/-46) mas in declination. For the overall difference between the offsets of Oberon and those of the other satellites, we have +3 (+/-30) mas in right ascension and -2 (+/-28) mas in declination. Ephemeris positions for the satellites were determined from DE432+ura111. Comparisons using other modern ephemerides for the solar system -INPOP13c- and for the motion of the satellites -NOE-7-2013- were also made. They confirm that the largest contribution to the offsets we find comes from the motion of the barycenter of the Uranus system around the barycenter of the solar system, as given by the planetary ephemerides. Catalogues with the observed positions are provided.Comment: 13 pages, 21 figure
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