112 research outputs found
Colloquy
Webster\u27s Dictionary defines colloquy as mutual discourse. Readers are encouraged to submit additions, corrections, and comments about earlier articles appearing in Word Ways. Comments received at least one month prior to publication of an issue will appear in that issue
Interactions between Schistosoma haematobium group species and their Bulinus spp. intermediate hosts along the Niger River Valley
Background
Urogenital schistosomiasis, caused by infection with Schistosoma haematobium, is endemic in Niger but complicated by the presence of Schistosoma bovis, Schistosoma curassoni and S. haematobium group hybrids along with various Bulinus snail intermediate host species. Establishing the schistosomes and snails involved in transmission aids disease surveillance whilst providing insights into snail-schistosome interactions/compatibilities and biology.
Methods
Infected Bulinus spp. were collected from 16 villages north and south of the Niamey region, Niger, between 2011 and 2015. From each Bulinus spp., 20â52 cercariae shed were analysed using microsatellite markers and a subset identified using the mitochondrial (mt) cox1 and nuclear ITS1â+â2 and 18S DNA regions. Infected Bulinus spp. were identified using both morphological and molecular analysis (partial mt cox1 region).
Results
A total of 87 infected Bulinus from 24 sites were found, 29 were molecularly confirmed as B. truncatus, three as B. forskalii and four as B. globosus. The remaining samples were morphologically identified as B. truncatus (nâ=â49) and B. forskalii (nâ=â2). The microsatellite analysis of 1124 cercariae revealed 186 cercarial multilocus genotypes (MLGs). Identical cercarial genotypes were frequently (60%) identified from the same snail (clonal populations from a single miracidia); however, several (40%) of the snails had cercariae of different genotypes (2â10 MLGâs) indicating multiple miracidial infections. Fifty-seven of the B. truncatus and all of the B. forskalii and B. globosus were shedding the Bovid schistosome S. bovis. The other B. truncatus were shedding the human schistosomes, S. haematobium (nâ=â6) and the S. haematobium group hybrids (nâ=â13). Two B. truncatus had co-infections with S. haematobium and S. haematobium group hybrids whilst no co-infections with S. bovis were observed.
Conclusions
This study has advanced our understanding of human and bovid schistosomiasis transmission in the Niger River Valley region. Human Schistosoma species/forms (S. haematobium and S. haematobium hybrids) were found transmitted only in five villages whereas those causing veterinary schistosomiasis (S. bovis), were found in most villages. Bulinus truncatus was most abundant, transmitting all Schistosoma species, while the less abundant B. forskalii and B. globosus, only transmitted S. bovis. Our data suggest that species-specific biological traits may exist in relation to co-infections, snail-schistosome compatibility and intramolluscan schistosome development
Energy densities in the strong-interaction limit of density functional theory
We discuss energy densities in the strong-interaction limit of density
functional theory, deriving an exact expression within the definition (gauge)
of the electrostatic potential of the exchange-correlation hole. Exact results
for small atoms and small model quantum dots are compared with available
approximations defined in the same gauge. The idea of a local interpolation
along the adiabatic connection is discussed, comparing the energy densities of
the Kohn-Sham, the physical, and the strong-interacting systems. We also use
our results to analyze the local version of the Lieb-Oxford bound, widely used
in the construction of approximate exchange-correlation functionals.Comment: 12 page
ModÚle de prévision de défaillances sur des réseaux à faible historique de maintenance
Statistical models to forecast the state of pipe networks have been developed to help decision makers in the field of renewal of drinking water networks. To enlarge the application of the method to services with low maintenance history, a method of data reconstitution from services on which observations over longer periods are available, has been proposed. Processing of reconstituted and real data, from the moment data have been recorded on breakdowns, is the principle of the learning method presented here. / Des modÚles statistiques de prévision de l'état des canalisations ont été développés pour aider les décideurs dans le domaine du renouvellement des réseaux d'eau potable. Afin d'étendre le champ d'application de la méthode aux services ayant un faible historique de maintenance, il est proposé une méthode de reconstitution de données à partir de services sur lesquels sont disponibles des observations sur une longue période. Le traitement des données ainsi reconstituées et des données réelles depuis la date de début de l'archivage des incidents constitue le principe de la méthode d'apprentissage présentée ici
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