Tension chylothorax after coronary artery bypass graft surgery

Bozok, Sahin/0000-0002-1256-5055WOS: 000334902700031Chylothorax is a rare yet serious complication after coronary artery bypass grafting (CABG), with a poor prognosis, unless left untreated appropriately. A 70-year-old male patient, who underwent CABG with internal thoracic artery and saphenous vein grafts three weeks prior was admitted to the emergency service with severe dyspnea and shock. Chest X-ray revealed left-sided massive pleural effusion. The patient was diagnosed with tension chylothorax and a left tube thoracostomy was performed. The patient was then discharged with conservative treatment

Unusual Cause of Cardiac Compression in a Trauma Patient: Cystic Thymoma

[West J Emerg Med. 2012;13(6):527-528

Unusual Cause of Cardiac Compression in a Trauma Patient: Cystic Thymoma

[West J Emerg Med. 2012;13(6):527-528

?-Tocopherol and ascorbic acid in early postoperative period of cardiopulmonary bypass

PubMed: 22885531AIM: To investigate whether ?-tocopherol and ascorbic acid have effect on the suppression of inflammation in the early postoperative period after open heart surgery. METHODS: A total of 59 patients who had undergone cardiopulmonary bypass (CPB) in the Cardiovascular Surgery Department of a tertiary center between June 2008 and December 2008 were retrospectively investigated. The study group consisted of 34 patients (25 men, 9 women) to whom ascorbic acid (500mg/day) and ?-tocopherol (300mg/day) were administered on the day of operation (0th day) and the first four consecutive postoperative days. In contrast, 25 controls (20 men, 5 women) received no additional anti-inflammatory medications. The two groups were compared in terms of demographics, blood parameters such as C-reactive protein (CRP) and white blood cell (WBC) count, and durations of cross-clamp and CPB. RESULTS: In the control group, CRP levels were found to be increased on the first postoperative day (P<0.001) and CRP levels were correlated with triglyceride levels on the day of operation (P=0.009) and the first postoperative day (P=0.021). On the second postoperative day WBC count was found to be decreased (P=0.008) and correlated with glucose level (P<0.005). In the study group, CRP levels were found to be inversely correlated with serum high-density lipoprotein (HDL) (P=0.049) on the first postoperative day and directly correlated with triglyceride levels on the second postoperative day (P=0.017). Blood glucose levels were found to be increased on the first postoperative day (P=0.021) and a correlation was detected between WBC count on the fourth postoperative day and doses of ascorbic acid and ?-tocopherol (P=0.027). CONCLUSION: Suppression of the systemic inflammatory response to CPB is a double-edged sword and whether this suppression aids in the attenuation of morbidity and mortality is obscure. In this respect, ascorbic acid and ?-tocopherol seem to display some anti-inflammatory effect, but further studies are necessary to reveal the actual therapeutic potential and the complex mechanism related to biochemical and inflammatory parameters. © 2012 Italian Federation of Cardiology

Functionalized polyisocyanides

Contains fulltext : 76543.pdf (publisher's version ) (Open Access)RU Radboud Universiteit Nijmegen, 18 januari 2010146 p

Diagnosis and management of carotid body tumor: a report of seven cases

Paragangliomas are rare asymptomatic painless tumors, originating from paraganglionic bodies of autonomous nerve system of the embriological neural crest and increasing gradually. Despite their gradual developing nature, it is critical to reach early diagnosis and tailor surgical plan for carotid body tumors due to their potential of being malignant and local aggressive development, as well as invasion or pressure on the adjacent vascular and neural tissues. In this article, we present seven cases who were admitted with the complaints of pain and swelling in the neck and were diagnosed with carotid body tumor based on the further investigations and were surgically treated in the light of literature review and different surgical modalities were discussed

Anatomical and functional changes after aortic valve replacement with different sizes of mechanical valves

Bozok, Sahin/0000-0002-1256-5055WOS: 000457731600002PubMed: 30059131Objective: To date. there is no consensus on the selection of type and size of prosthetic valve for aortic valve replacement (AVR). the aim of this study was to compare anatomical and functional changes occurring in the left ventricle after AVR with different sizes of mechanical valves. Methods: A total of 92 patients with serious aortic valve stenosis. who underwent AVR between March 2001 and June 2008 using mechanical valves of different sizes. were retrospectively analysed. the sizes of mechanical valves v ere 19, 21, 23 and 25 mm. All patients were assessed pre-operatively and at six months and in first, third and fifth years postoperatively. the left ventricle was assessed with electrocardiography, echocardiography and telecardiography and compared in the four patient groups, constituted according to the mechanical valve size used. Results: in all groups, left ventricular mass and mass index. transvalvular aortic gradient. thicknesses of the interventricular septum and posterior wall and left ventricular end-systolic and end-diastolic diameters had decreased significantly post surgery. Left ventricular ejection fraction and exercise capacity had increased significantly (p < 0.001). the most noteworthy anatomical and functional improvements were seen in patients who had received 23- and 25-mm mechanical valves. Conclusion: Mechanical valve e replacement should not be performed with small size Ayes because of the higher residual gradient