Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinicoradiological study

Although long-term exposure of the brain to increased GH/IGF-1 likely influences cerebral functions, no in vivo studies have been directed towards changes of the brain structure in acromegaly. Here, we used high resolution magnetic resonance images to compare volumes of gray matter (GM), white matter (WM) and cerebrospinal fluid (CSF) of forty-four patients with acromegaly to an age and gender matched, healthy control group (n = 44). In addition, white matter lesions (WMLs) were quantified and graded. Patients exhibited larger GM (+3.7% compared with controls, P = 0.018) and WM volumes (+5.1%, P = 0.035) at the expense of CSF. Differences of WML counts between patients and controls were subtle, however, showing more patients in the 21–40 lesions category (P = 0.044). In conclusion, this MRI study provides first evidence that acromegalic patients exhibit disturbances of the macroscopic brain tissue architecture. Furthermore, acromegalic patients may have an increased risk of neurovascular pathology, likely due to secondary metabolic and vascular comorbidities

Electroweak parameters of the z0 resonance and the standard model

Contains fulltext : 124399.pdf (publisher's version ) (Open Access

A Study of the reaction e+ e- ---> mu+ mu- around the Z0 pole

Contains fulltext : 129369.pdf (publisher's version ) (Open Access

Charged particle multiplicity distributions in Z0 hadronic decays

This paper presents an analysis of the multiplicity distributions of charged particles produced in Z0 hadronic decays in the DELPHI detector. It is based on a sample of 25364 events. The average multiplicity is =20.71±0.04(stat)±0.77(syst) and the dispersion D=6.28±0.03(stat)±0.43(syst). The data are compared with the results at lower energies and with the predictions of phenomenological models. The Lund parton shower model describes the data reasonably well. The multiplicity distributions show approximate KNO-scaling. They also show positive forward-backward correlations that are strongest in the central region of rapidity and for particles of opposite charge. © 1991 Springer-Verlag.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Electroweak parameters of the Z0^0 resonance and the standard model

Media temporalities of the elderly : evolutions in stability This article shows the context of analysis and the first results of a research on media temporalities of the elderly. Several works have finely analysed the diversity of the media practices and studied meanings of media uses. I wish to continue these analyses by insisting on the evolutionary and dynamic aspect of the practices and temporalities of users having expanded, enhanced, so called "interactive" radio and especially television programming. A priori, the elderly, upon retirement, have a "full-time free time". Their media practices seem strongly influenced by their first experiments ; the appropriation of the various peripheral accessories which gradually came with the media, to the latest digital ones, seems to reinforce their habits of watching television. Their representations and relations with times and media are very far away from the image of television like omnipresent media or "devourer of time". Rather, their media practices are to be understood like a temporality of the occupation, according to the expression of Gerard Derèze, characterized by interest and utility. A particular glance at the users who do not carry out a systematic selection of the programs, accepting the unforeseen, highlights an approach of media and time that allow "useful encounter" which I would qualify in a first stage by : "chance and encounter" and "random and the following". The few points presented here make me assume that the global relation of the autonomous elderly persons to the media can evolve when confronted to their new temporal framework and the new program offer, whereas their representations and use of the media remain quite stable

Charged Particle Multiplicity Distributions in Restricted Rapidity Intervals in Z0 Hadronic Decays

The multiplicity distributions of charged particles in restricted rapidity intervals in Z0 hadronic decays measured by the DELPHI detector are presented. The data reveal a shoulder structure, best visible for intervals of intermediate size, i.e. for rapidity limits around ±1.5. The whole set of distributions including the shoulder structure is reproduced by the Lund Parton Shower model. The structure is found to be due to important contributions from 3-and 4-jet events with a hard gluon jet. A different model, based on the concept of independently produced groups of particles, "clans", fluctuating both in number per event and particle content per clan, has also been used to analyse the present data. The results show that for each interval of rapidity the average number of clans per event is approximately the same as at lower energies. © 1991 Springer-Verlag.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Electroweak parameters of the Z0^0 resonance and the standard model

Media temporalities of the elderly : evolutions in stability This article shows the context of analysis and the first results of a research on media temporalities of the elderly. Several works have finely analysed the diversity of the media practices and studied meanings of media uses. I wish to continue these analyses by insisting on the evolutionary and dynamic aspect of the practices and temporalities of users having expanded, enhanced, so called "interactive" radio and especially television programming. A priori, the elderly, upon retirement, have a "full-time free time". Their media practices seem strongly influenced by their first experiments ; the appropriation of the various peripheral accessories which gradually came with the media, to the latest digital ones, seems to reinforce their habits of watching television. Their representations and relations with times and media are very far away from the image of television like omnipresent media or "devourer of time". Rather, their media practices are to be understood like a temporality of the occupation, according to the expression of Gerard Derèze, characterized by interest and utility. A particular glance at the users who do not carry out a systematic selection of the programs, accepting the unforeseen, highlights an approach of media and time that allow "useful encounter" which I would qualify in a first stage by : "chance and encounter" and "random and the following". The few points presented here make me assume that the global relation of the autonomous elderly persons to the media can evolve when confronted to their new temporal framework and the new program offer, whereas their representations and use of the media remain quite stable