Complete determination of neutron yield from 62 MeV protons on 9Be for the design of a low – power ADS

Within the European Partitioning & Transmutation research programs, infrastructures specifically dedicated to the study of fundamental reactor physics of future fast neutron-based reactors are very important. In this respect, an Accelerator Driven System low-power prototype, based on a 70 MeV proton beam impinging on a thick Beryllium converter, was recently proposed and designed within the INFN-E project. The world data on neutron yield from Be target are scarce in this proton energy range. This lack of data calls for a dedicated measurement which was performed at INFN Laboratori Nazionali del Sud, covering a wide angular range, from 0 to 150 degrees, and an almost complete neutron energy interval, from thermal up to the beam energy. In this contribution the results are discussed together with the description of the proposed ADS facility

Study of an intrinsically safe infrastructure for training and research on nuclear technologies

Within European Partitioning & Transmutation research programs, infrastructures specifically dedicated to the study of fundamental reactor physics and engineering parameters of future fast-neutron-based reactors are very important, being some of these features not available in present zero-power prototypes. This presentation will illustrate the conceptual design of an Accelerator-Driven System with high safety standards, but ample flexibility for measurements. The design assumes as base option a 70MeV, 0.75mA proton cyclotron, as the one which will be installed at the INFN National Laboratory in Legnaro, Italy and a Beryllium target, with Helium gas as core coolant. Safety is guaranteed by limiting the thermal power to 200 kW, with a neutron multiplication coefficient around 0.94, loading the core with fuel containing Uranium enriched at 20% inserted in a solid-lead diffuser. The small decay heat can be passively removed by thermal radiation from the vessel. Such a system could be used to study, among others, some specific aspects of neutron diffusion in lead, beam-core coupling, target cooling and could serve as a training facility

Deep-Subwavelength-Optimized Holey-Structured Metamaterial Lens for Nonlinear Air-Coupled Ultrasonic Imaging

Ultrasound non-destructive testing (NDT) is a common technique used for defect detection in different materials, from aluminium to carbon-fiber-reinforced polymers (CFRPs). In most cases, a liquid coupling medium/immersion of the inspected component is required to maximize impedance matching, limiting the size of the structure and materials. Air-coupled inspection methods have recently been developed for noncontact inspections to reduce contact issues in standard ultrasonic inspections. However, transmission of ultrasound in air is very inefficient because of the enormous impedance mismatch between solids and air, thus requiring a signal amplification system of high-sensitivity transducers. Hence, the captured signal amplitude may not be high enough to reveal any wave distortion due to defects or damage. This work presents a design of a holey-structured metamaterial lens with a feature size of λ/14 aiming at improvement of acousto-ultrasonic imaging using air-coupled transducers. The required effect is obtained by matching geometrical parameters of the proposed holey-structured metamaterials and the Fabry–Perot resonance modes of the structure. Transmission tests have been conducted on different fabricated metamaterial-based structures, to assess the frequency component filtering of the proposed method in both acoustic (f = 5 kHz, 20 kHz) and ultrasonic range (f = 30 kHz, 40 kHz). Results showed an improved sensitivity of damage imaging, with an increase in amplitude of the design frequencies of the lens by 11 dB. Air-coupled inspections were conducted on a stress-corrosion cracked aluminum plate and impacted CFRP plate using the holey-structured lens. Results showed an improvement in the damage-imaging resolution due to a wave-amplitude increase across the defective features, thus demonstrating its potential as an efficient and sensitive inspection tool for damage-detection improvement in geometrically complex components of different materials

Ceramic Materials for Biomedical Applications: An Overview on Properties and Fabrication Processes

A growing interest in creating advanced biomaterials with specific physical and chemical properties is currently being observed. These high-standard materials must be capable to integrate into biological environments such as the oral cavity or other anatomical regions in the human body. Given these requirements, ceramic biomaterials offer a feasible solution in terms of mechanical strength, biological functionality, and biocompatibility. In this review, the fundamental physical, chemical, and mechanical properties of the main ceramic biomaterials and ceramic nanocomposites are drawn, along with some primary related applications in biomedical fields, such as orthopedics, dentistry, and regenerative medicine. Furthermore, an in-depth focus on bone-tissue engineering and biomimetic ceramic scaffold design and fabrication is presented

Design and characterization of a dual modality (SPET-US) tomographic device

In the last few years, integrated dual-imaging systems have emerged as a new modality for cancer staging with the aim to offer both functional and anatomic information. At moment the prevalent dual modality devices are based on Computer Tomography and Positron Emission Tomography. In this sense, the scientific community is debating about the high effective dose to the patient, representing an indicator of the stochastic risk, especially from Computer Tomography examination. So, a new dual modality imager, based on a Ultrasound probe and a Single Photon Emission Tomography was made in order to combine functional information, from gamma camera with structural one, obtained from the Ultrasound equipment. The Ultrasound probe is the most diffuse anatomical examination device at zero-dose, using a cost-effective and reliable method with few restriction in use. The proposed Single Photon Emission Tomography detector is a compact gamma camera (10x10 cm(2) active area), based on LaBr3:Ce scintillation crystal coupled to 4x4 array of Hamamatsu HS500-CMODS Multi Anode Photomultiplier, with high spatial and energy resolution performances, equipped with rotating slanthole collimator. A calibration phantom, made of a Co-57 point source inside a water filled box, was utilized to acquire 3D dual modality images. The detector has shown good performances in terms of spatial resolution and localization along z-axis of object of interest. This project was developed by several Italian Universities under an INFN collaboration

Liquid biopsy of cerebrospinal fluid enables selective profiling of glioma molecular subtypes at first clinical presentation

NGS analysis - Complete dataset.</p

Study of an intrinsically safe infrastructure for training and research on nuclear technologies

Within European Partitioning & Transmutation research programs, infrastructures specifically dedicated to the study of fundamental reactor physics and engineering parameters of future fast-neutron-based reactors are very important, being some of these features not available in present zero-power prototypes. This presentation will illustrate the conceptual design of an Accelerator-Driven System with high safety standards, but ample flexibility for measurements. The design assumes as base option a 70MeV, 0.75mA proton cyclotron, as the one which will be installed at the INFN National Laboratory in Legnaro, Italy and a Beryllium target, with Helium gas as core coolant. Safety is guaranteed by limiting the thermal power to 200 kW, with a neutron multiplication coefficient around 0.94, loading the core with fuel containing Uranium enriched at 20% inserted in a solid-lead diffuser. The small decay heat can be passively removed by thermal radiation from the vessel. Such a system could be used to study, among others, some specific aspects of neutron diffusion in lead, beam-core coupling, target cooling and could serve as a training facility