A case of atypical disseminated herpes simplex virus 1 with hepatitis in a liver transplant recipient: the need for dermatologic evaluation

Disseminated herpes simplex virus (HSV) is mainly seen in immunocompromised individuals. Atypical lesions can be present in both primary infection and reactivation disease. Compared with the general population, inmunocompromised hosts are at greater risk of increased persistency and severity of clinical manifestations, including severe systemic involvement such as esophagitis, meningitis, and hepatitis. Herein, we report the case of a liver transplant recipient with atypical disseminated herpes simplex virus-1 complicated by HSV-related hepatitis. Dermatological consultation and histological assessment were crucial for a correct diagnosis and treatment

The application of chiroptical spectroscopy (circular dichroism) in quantifying binding events in lanthanide directed synthesis of chiral luminescent self-assembly structures

The binding of asymmetrical and optically pure tridentate ligands (L = 1(S) and 1(R)) containing one carboxylic group and 2-naphthyl as an antenna to lanthanide ions (M = La(III) and Eu(III)) was studied in CH3CN, showing the successive formation of M:L, M:L2 and M:L3 stoichiometric species in solution. The europium complexes EuL3 were also synthesised, structurally characterised and their photophysical properties probed in CH3OH and CH3CN. The changes in the chiroptical properties of both 1(S) and 1(R) were used (by circular dichroism (CD) spectroscopy) to monitor the formation of these chiral selfassemblies in solution. While circularly polarised luminescence (CPL) showed the formation of Eu(1(S))3 and Eu(1(R))3 as enantiomers, with high luminescence dissymmetry factors (glum), fitting the CD changes allowed for binding constants to be determined that were comparable to those seen in the analyses of absorbance and luminescence changes

Capas finas de ZrO2 para mejorar la resistencia química de los vidriados mates de calcio

La resistencia al ataque químico de vidriados cerámicos susceptibles al mismo, concretamente formulados a partir de una frita mate de calcio, se ha mejorado depositando en la superficie una capa delgada de óxido de circonio. Un sol de circonio estabilizado es el precursor de la capa, el cual se deposita mediante aerografía sobre el vidriado cocido y con un tratamiento térmico suave (Tmax ≈ 400 ºC), es transformado en ZrO2 y anclado a la superficie. Los ensayos de resistencia química demuestran que el vidriado protegido no sufre un ataque apreciable visualmente por parte del ácido clorhídrico concentrado, condiciones en las que el mismo vidriado sin el recubrimiento resulta gravemente dañado. El precursor utilizado genera una capa de óxido de circonio que protege el vidriado subyacente, de modo que el ataque químico por parte del ácido clorhídrico queda confinado al entorno de las grietas y discontinuidades de la capa depositadaPeer reviewe

Maintenance policy under multiple unrevealed failures

The unrevealed failures of a system are detected only by inspection. In this work, an inspection policy along with a maintenance procedure for multiunit systems with dependent times to failure is presented. The existence of an optimum policy is also discussed

Incumbent Actions in Adopting Preventive Innovations: Cases in the Finnish Construction Sector

Wood construction differs from traditional concrete materials in technical and organizational requirements for which it can be studied as an innovation, and thanks to health and climate change mitigation and prevention capabilities, wood construction can be categorized as a preventive innovation. The purpose of this study is to explore incumbent actions in the adoption of wood materials. The context of this paper is an interview study that analyzes public procurement of school buildings that illustrate the role of incumbent actions in the adoption of wood materials. We study the actions of incumbent organizations and identify how these actions relate to the preventive innovation’s elements of probability, severity, and time-lapse to see benefits. Findings indicate that the probability and severity of an unwanted event make incumbents more likely to select wood materials and future-oriented benefits are not a deterrent for adoption but instead, are often utilized to argue potentially larger investments. This study provides an overview of prevention-related benefits derived from building materials and highlights what construction sector incumbents ponder when adopting innovations.acceptedVersionPeer reviewe

Drought Resistance by Engineering Plant Tissue-Specific Responses

Drought is the primary cause of agricultural loss globally, and represents a major threat to food security. Currently, plant biotechnology stands as one of the most promising fields when it comes to developing crops that are able to produce high yields in water-limited conditions. From studies of Arabidopsis thaliana whole plants, the main response mechanisms to drought stress have been uncovered, and multiple drought resistance genes have already been engineered into crops. So far, most plants with enhanced drought resistance have displayed reduced crop yield, meaning that there is still a need to search for novel approaches that can uncouple drought resistance from plant growth. Our laboratory has recently shown that the receptors of brassinosteroid (BR) hormones use tissue-specific pathways to mediate different developmental responses during root growth. In Arabidopsis, we found that increasing BR receptors in the vascular plant tissues confers resistance to drought without penalizing growth, opening up an exceptional opportunity to investigate the mechanisms that confer drought resistance with cellular specificity in plants. In this review, we provide an overview of the most promising phenotypical drought traits that could be improved biotechnologically to obtain drought-tolerant cereals. In addition, we discuss how current genome editing technologies could help to identify and manipulate novel genes that might grant resistance to drought stress. In the upcoming years, we expect that sustainable solutions for enhancing crop production in water-limited environments will be identified through joint efforts

Modular Multi-level Converter Hardware-in-the-Loop Simulation on low-cost System-on-Chip devices

Comunicació presentada a IECON 2018 - 44th Annual Conference of the IEEE Industrial Electronics Society (October 21-23, 2018 Washington D.C., USA.)System-on-Chip (SoC) devices combine powerful general purpose processors, a Field-Programmable Gate Array (FPGA) and other peripherals which make them very convenient for Hardware-in-the-Loop (HIL) simulation. One of the limitations of these devices is that control engineers are not particularly familiarized with FPGA programming, which need extensive expertise in order to code these highly sophisticated algorithms using Hardware Description Languages (HDL). Notwithstanding, there exist High-Level Synthesis (HLS) tools which allow to program these devices using more generic programming languages such as C, C++ and SystemC. This paper evaluates SoC devices to implement a Modular Multi-Level Converter (MMC) model using HLS tools for being implemented in the FPGA fabric in order to perform HIL verification of control algorithms in a single low-cost device