New insights on planetary companions of GJ 1151

Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2021, Tutors: Manuel Perger, Carme Jordi i NebotThe LOFAR mission announced the detection of a radio emission coming from the M dwarf GJ 1151 which is consistent with the possible interaction of the star with an Earth-like exoplanet with an orbit of 1 to 5 d. Combining new data from different radial velocity surveys we calculate a new upper limit on the minimum mass of this possible companion at 0.9 M⊕ to 1.6 M⊕ for a 1.02 d to 5 d orbit. We also find evidence of a Neptune-like companion with a minimum mass of 10.6 ± 1.5 M⊕ on a 396 ± 6 d circular orbit and a likely more massive Neptunian exoplanet with a minimum mass of 24 ± 1.5 M⊕ on a 2093+130 d keplerian orbit

Robust 3D People Tracking and Positioning System in a Semi-Overlapped Multi-Camera Environment

People positioning and tracking in 3D indoor environments are challenging tasks due to background clutter and occlusions. Current works are focused on solving people occlusions in low-cluttered backgrounds, but fail in high-cluttered scenarios, specially when foreground objects occlude people. In this paper, a novel 3D people positioning and tracking system is presented, which shows itself robust to both possible occlusion sources: static scene objects and other people. The system holds on a set of multiple cameras with partially overlapped fields of view. Moving regions are segmented independently in each camera stream by means of a new background modeling strategy based on Gabor filters. People detection is carried out on these segmentations through a template-based correlation strategy. Detected people are tracked independently in each camera view by means of a graph-based matching strategy, which estimates the best correspondences between consecutive people segmentations. Finally, 3D tracking and positioning of people is achieved by geometrical consistency analysis over the tracked 2D candidates, using head position (instead of object centroids) to increase robustness to foreground occlusions

ALBERTI, a Multilingual Domain Specific Language Model for Poetry Analysis

The computational analysis of poetry is limited by the scarcity of tools to automatically analyze and scan poems. In a multilingual settings, the problem is exacerbated as scansion and rhyme systems only exist for individual languages, making comparative studies very challenging and time consuming. In this work, we present \textsc{Alberti}, the first multilingual pre-trained large language model for poetry. Through domain-specific pre-training (DSP), we further trained multilingual BERT on a corpus of over 12 million verses from 12 languages. We evaluated its performance on two structural poetry tasks: Spanish stanza type classification, and metrical pattern prediction for Spanish, English and German. In both cases, \textsc{Alberti} outperforms multilingual BERT and other transformers-based models of similar sizes, and even achieves state-of-the-art results for German when compared to rule-based systems, demonstrating the feasibility and effectiveness of DSP in the poetry domain.Comment: Accepted for publication at SEPLN 2023: 39th International Conference of the Spanish Society for Natural Language Processin

Generalized erythematous scaly rash after glucocorticoids

A 65-years-old woman with a medical history of idiopathic throm- bocytopenic purpura and psoriasis in treatment with topical glucocor- ticoids presented with a three-month history of burning, generalized erythematous, scaly rash, and chills. A few weeks before the rash, the patient presented petechiae on her thighs due to a low platelet count (28.000 platelets per microliter), for which she started treatment with prednisone 25 mg/week. The rash was initially treated with topical ointments including clobetasol, urea, salicylic acid, ammonium lactate, and propylene glycol without improvement. The physical examination showed generalized erythroderma (Fig. 1A) from neck to feet (Fig. 1B), with thick silvery desquamation respecting the face and back of the legs (Fig. 1C), involving more than 90% of the patient’s body surface area and erythematous scaly plaques on the scalp. Laboratory test results were normal. A punch biopsy specimen obtained from an arm area showed increased keratinization at the level of the corneal layer with compact parakeratosis with abundant polymorphonuclear cells. The epidermis presented psoriasiform hyperplasia with significant spongio- sis. What is the diagnosis

Improving automatic detection of obstructive sleep apnea through nonlinear analysis of sustained speech

We present a novel approach for the detection of severe obstructive sleep apnea (OSA) based on patients' voices introducing nonlinear measures to describe sustained speech dynamics. Nonlinear features were combined with state-of-the-art speech recognition systems using statistical modeling techniques (Gaussian mixture models, GMMs) over cepstral parameterization (MFCC) for both continuous and sustained speech. Tests were performed on a database including speech records from both severe OSA and control speakers. A 10 % relative reduction in classification error was obtained for sustained speech when combining MFCC-GMM and nonlinear features, and 33 % when fusing nonlinear features with both sustained and continuous MFCC-GMM. Accuracy reached 88.5 % allowing the system to be used in OSA early detection. Tests showed that nonlinear features and MFCCs are lightly correlated on sustained speech, but uncorrelated on continuous speech. Results also suggest the existence of nonlinear effects in OSA patients' voices, which should be found in continuous speech

Exploring differences between phonetic classes in Sleep Apnoea Syndrome Patients using automatic speech processing techniques

This work is part of an on-going collaborative project between the medical and signal processing communities to promote new research efforts on automatic OSA (Obstructive Apnea Syndrome) diagnosis. In this paper, we explore the differences noted in phonetic classes (interphoneme) across groups (control/apnoea) and analyze their utility for OSA detectio

Pseudoartrosis congénita bilateral de la clavícula: a propósito de un caso familiar

Presentamos una paciente de nueve meses con pseudoartrosis congénita bilateral de ambas clavículas, cuya madre presenta el mismo cuadro. Dicho cuadro es una entidad rara, pobremente documentada en la ortopedia pediátrica. La etiología y patogenia aún permanece oscura. La apariencia clínico-radiológica consiste en la ausencia desde el nacimiento de un defecto de unión a nivel del tercio medio clavicular característico. El diagnóstico diferencial debe hacerse con las fracturas perinatales, pseudoartrosis postraumáticas y disostosis cleido-craneales.The case of a female patient of nine months of are and her mother, 41-year-old showing a Congenital Bilateral Pseudoarthrosis of the clavicle are presented. This is a rare entity that has been poorly documented in paediatrics orthopedics literature. The etiology and pathogenesis still remain unclear. The clinical and radiological appearance are characteristic. Differential diagnosis lies between postpartum fractures, postraumatic pseudoarthrosis, and cleidocraneal dysostosis

On-Surface Cucurbit[n]uril Supramolecular Recognition for an Optical Sensor Design

This is the peer reviewed version of the following article: ChemistrySelect 2019, 4, 7036 7041, which has been published in final form at https://doi.org/10.1002/slct.201901127. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.[EN] A novel optical sensor, based on the use of the macrocyclic receptor cucurbit[7]uril as molecular selector taking part of a sensing poly(vinyl chloride)-based membrane immobilized onto a quartz slide surface, has been developed and tested to thiabendazole analysis. The method is built upon the increase of the thiabendazole fluorescence as a result of the supramolecular recognition event. Variables involved in the membrane construction and fluorescence measurements have been evaluated and optimized. The sensing membrane is prepared by a spin-coating procedure (1 min at 800 r.p.m.). An increase of more than 2 fold in the fluorescence signal is observed when the supramolecular complex is immobilized into the membrane respect to that observed for the free guest. Under optimized conditions, the dispositive responds in a few seconds to thiabendazole concentrations at 10(-7) M level. In addition, the characterization of the supramolecular complex together with lifetime measurements is included.The authors would like to thank the Comunidad Autonoma de Madrid (P2018/NMT-4349, TRANSNANOAVANSENS-CM) for financial support.Jiménez, J.; Blasco, S.; Blanco, E.; Atienzar Corvillo, PE.; Del Pozo, M.; Quintana, C. (2019). On-Surface Cucurbit[n]uril Supramolecular Recognition for an Optical Sensor Design. ChemistrySelect. 4(24):7036-7041. https://doi.org/10.1002/slct.201901127S70367041424Montes-Navajas, P., Baumes, L. A., Corma, A., & Garcia, H. (2009). Dual-response colorimetric sensor array for the identification of amines in water based on supramolecular host–guest complexation. Tetrahedron Letters, 50(20), 2301-2304. doi:10.1016/j.tetlet.2009.02.189Telting-Diaz, M., & Bakker, E. (2002). Mass-Produced Ionophore-Based Fluorescent Microspheres for Trace Level Determination of Lead Ions. Analytical Chemistry, 74(20), 5251-5256. doi:10.1021/ac025596iUttam, B., Hussain, M. A., Joshi, S., & Rao, C. P. (2018). Physicochemical and Ion-Sensing Properties of Benzofurazan-Appended Calix[4]arene in Solution and on Gold Nanoparticles: Spectroscopy, Microscopy, and DFT Computations in Support of the Species of Recognition. ACS Omega, 3(12), 16989-16999. doi:10.1021/acsomega.8b02848Shamsipur, M., Sadeghi, M., Beyzavi, M. H., & Sharghi, H. (2015). Development of a novel fluorimetric bulk optode membrane based on meso-tetrakis(2-hydroxynaphthyl) porphyrin (MTHNP) for highly sensitive and selective monitoring of trace amounts of Hg2+ ions. Materials Science and Engineering: C, 48, 424-433. doi:10.1016/j.msec.2014.12.030Cano-Raya, C., Fernández-Ramos, M. D., Gómez-Sánchez, J., & Capitán-Vallvey, L. F. (2006). Irreversible optical sensor for mercury determination based on tetraarylborate decomposition. Sensors and Actuators B: Chemical, 117(1), 135-142. doi:10.1016/j.snb.2005.11.009Sahari, A., Ruckh, T. T., Hutchings, R., & Clark, H. A. (2015). Development of an Optical Nanosensor Incorporating a pH-Sensitive Quencher Dye for Potassium Imaging. Analytical Chemistry, 87(21), 10684-10687. doi:10.1021/acs.analchem.5b03080Assaf, K. I., & Nau, W. M. (2015). Cucurbiturils: from synthesis to high-affinity binding and catalysis. Chemical Society Reviews, 44(2), 394-418. doi:10.1039/c4cs00273cGanguly, A., Ghosh, S., & Guchhait, N. (2016). Inclusion of an Anthracene-based Fluorophore within Molecular Containers: A Comparative Study of the Cucurbituril and Cyclodextrin Host Families. The Journal of Physical Chemistry B, 120(19), 4421-4430. doi:10.1021/acs.jpcb.6b04178Rankin, M. A., & Wagner, B. D. (2004). Fluorescence Enhancement of Curcumin upon Inclusion into Cucurbituril. Supramolecular Chemistry, 16(7), 513-519. doi:10.1080/10610270412331283583Geng, Q.-X., Cong, H., Tao, Z., Lindoy, L. F., & Wei, G. (2015). Cucurbit[7]uril-improved recognition by a fluorescent sensor for cadmium and zinc cations. Supramolecular Chemistry, 28(9-10), 784-791. doi:10.1080/10610278.2015.1117614Smith, L. C., Leach, D. G., Blaylock, B. E., Ali, O. A., & Urbach, A. R. (2015). Sequence-Specific, Nanomolar Peptide Binding via Cucurbit[8]uril-Induced Folding and Inclusion of Neighboring Side Chains. Journal of the American Chemical Society, 137(10), 3663-3669. doi:10.1021/jacs.5b00718Lazar, A. I., Biedermann, F., Mustafina, K. R., Assaf, K. I., Hennig, A., & Nau, W. M. (2016). Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications. Journal of the American Chemical Society, 138(39), 13022-13029. doi:10.1021/jacs.6b07655Del Pozo, M., Fernández, Á., & Quintana, C. (2018). On-line competitive host-guest interactions in a turn-on fluorometric method to amantadine determination in human serum and pharmaceutical formulations. Talanta, 179, 124-130. doi:10.1016/j.talanta.2017.10.064Pozo, M. del, Blanco, E., Fatás, E., Hernández, P., & Quintana, C. (2012). New supramolecular interactions for electrochemical sensors development: different cucurbit[8]uril sensing platform designs. The Analyst, 137(18), 4302. doi:10.1039/c2an35325cDel Pozo, M., Hernández, P., Hernández, L., & Quintana, C. (2011). The use of cucurbit[8]uril host–guest interactions in the development of an electrochemical sensor: characterization and application to tryptophan determination. Journal of Materials Chemistry, 21(35), 13657. doi:10.1039/c1jm12063hDel Pozo, M., Mejías, J., Hernández, P., & Quintana, C. (2014). Cucurbit[8]uril-based electrochemical sensors as detectors in flow injection analysis. Application to dopamine determination in serum samples. Sensors and Actuators B: Chemical, 193, 62-69. doi:10.1016/j.snb.2013.11.074Demets, G. J.-F., Schneider, B. V. S., Correia, H. D., Gonçalves, R. R., Nobre, T. M., & Darbello Zaniquelli, M. E. (2008). A Technique to Produce Thin Cucurbit[6]uril Films. Journal of Nanoscience and Nanotechnology, 8(1), 432-435. doi:10.1166/jnn.2008.051Liu, M., Kan, J., Yao, Y., Zhang, Y., Bian, B., Tao, Z., … Xiao, X. (2019). Facile preparation and application of luminescent cucurbit[10]uril-based porous supramolecular frameworks. Sensors and Actuators B: Chemical, 283, 290-297. doi:10.1016/j.snb.2018.12.024Nicolas, H., Yuan, B., Zhang, J., Zhang, X., & Schönhoff, M. (2015). Cucurbit[8]uril as Nanocontainer in a Polyelectrolyte Multilayer Film: A Quantitative and Kinetic Study of Guest Uptake. Langmuir, 31(39), 10734-10742. doi:10.1021/acs.langmuir.5b02806Nicolas, H., Yuan, B., Zhang, X., & Schönhoff, M. (2016). Cucurbit[8]uril-Containing Multilayer Films for the Photocontrolled Binding and Release of a Guest Molecule. Langmuir, 32(10), 2410-2418. doi:10.1021/acs.langmuir.6b00128Del Pozo, M., Alonso, M., Hernández, L., & Quintana, C. (2010). An Electrochemical Approach for the Cucurbit[7]uril/Carbendazim Supramolecular Inclusion Complex. Application to Carbendazim Determination in Apples. Electroanalysis, 23(1), 189-195. doi:10.1002/elan.201000442Saleh, N., Koner, A. L., & Nau, W. M. (2008). Activation and Stabilization of Drugs by Supramolecular pKaShifts: Drug‐Delivery Applications Tailored for Cucurbiturils. Angewandte Chemie International Edition, 47(29), 5398-5401. doi:10.1002/anie.200801054http://ec.europa.eu/food/plant/pesticides/eu-pesticides-database/;Yu, F., Su, M., Tian, L., Wang, H., & Liu, H. (2018). Organic Solvent as Internal Standards for Quantitative and High-Throughput Liquid Interfacial SERS Analysis in Complex Media. Analytical Chemistry, 90(8), 5232-5238. doi:10.1021/acs.analchem.8b00008Chen, Q., Zuo, J., He, X., Mo, X., Tong, P., & Zhang, L. (2017). Enhanced fluorescence of terbium with thiabendazole and application in determining trace amounts of terbium and thiabendazole. Talanta, 162, 540-546. doi:10.1016/j.talanta.2016.10.036ASGHAR, M., YAQOOB, M., MUNAWAR, N., & NABI, A. (2016). Flow-Injection Determination of Thiabendazole Fungicide in Water Samples Using a Diperiodatocuprate(III)–Sulfuric Acid–Chemiluminescence System. Analytical Sciences, 32(3), 337-342. doi:10.2116/analsci.32.337Sousa, E. S., Pinto, L., & de Araujo, M. C. U. (2017). A chemometric cleanup using multivariate curve resolution in liquid chromatography: Quantification of pesticide residues in vegetables. Microchemical Journal, 134, 131-139. doi:10.1016/j.microc.2017.05.017Oliveira, A. M., Loureiro, H. C., de Jesus, F. F. S., & de Jesus, D. P. (2017). Electromembrane extraction and preconcentration of carbendazim and thiabendazole in water samples before capillary electrophoresis analysis. Journal of Separation Science, 40(7), 1532-1539. doi:10.1002/jssc.201601305Smitka, J., Lemos, A., Porel, M., Jockusch, S., Belderrain, T. R., Tesařová, E., & Da Silva, J. P. (2014). Phototransformation of benzimidazole and thiabendazole inside cucurbit[8]uril. Photochem. Photobiol. Sci., 13(2), 310-315. doi:10.1039/c3pp50336dMontes-Navajas, P., Corma, A., & Garcia, H. (2008). Complexation and Fluorescence of Tricyclic Basic Dyes Encapsulated in Cucurbiturils. ChemPhysChem, 9(5), 713-720. doi:10.1002/cphc.200700735Shewale, M. N., Lande, D. N., & Gejji, S. P. (2016). Encapsulation of benzimidazole derivatives within cucurbit[7]uril: Density functional investigations. Journal of Molecular Liquids, 216, 309-317. doi:10.1016/j.molliq.2015.12.076An, Q., Dong, C., Zhu, W., Tao, C., Yang, H., Wang, Y., & Li, G. (2012). Cucurbit[8]uril as Building Block for Facile Fabrication of Well-Defined Organic Crystalline Nano-objects with Multiple Morphologies and Compositions. Small, 8(4), 562-568. doi:10.1002/smll.20110193

Evolución macroeconómica de Italia durante las ultimas dos décadas.

En este trabajo se explica le evolución macroeconómica de Italia durante las ultimas dos décadas explicando sus variables mas relevantes

Osteopoiquilosis y síndrome de Buschke-Ollendörf: a propósito de un caso

Presentamos una paciente de 22 años que tras estudios radiológicos rutinarios, muestra una displasia ósea condensante, completamente asintomática e inócua, que afectaba principalmente pelvis y extremidades distales, mientras que las costillas, cráneo y columna dorsolumbar estaban indemnes. Asimismo, aparecen nevus elásticos y fibromas en la piel. Esta entidad no puede confundirse con un carcinoma metastásico esclerosante, esclerosis tuberosa u otras displasias como la melorreostosis.A female patient, 22 years oíd, showing characteristic sclerotic bone images on radiographic examinations is reported. The main locations were on the distal limbs and pelvis. She has also elastic nevi as freckles in the skin. This entity was not stablished as inhered process. The differential diagnosis lies between sclerotic metastasis, neurofibromatosis (Von Recklinghausen), Bourneville disease and other displastyc lesions