Factors That Affect Nursing Students’ Willingness to Respond to Disasters or Public Health Emergencies

Conditions throughout the United States are such that the frequency and intensity of disasters have increased, affecting more people, thereby increasing the demand on healthcare facilities and disaster response organizations. The demands to protect and care for existing patients while also providing medical care to victims of disasters can exacerbate the existing shortage of nurses. Alternative human resource strategies should consider the potential use of nursing students to increase available personnel resources. Unfortunately, little is known about the willingness of nursing students to help during a disaster. The purpose of this study was to examine willingness to respond among student nurses and identify factors that affected willingness. A quantitative research design using an online survey collected data from baccalaureate-level registered nursing students at two universities (n=110) during the Spring 2016 semester. The findings depicted a high level of overall willingness to respond to a disaster, with student nurses more willing to respond to natural disasters than human-caused disasters. Factors such as fear for personal safety, type of disaster, and lack of training were negatively correlated with willingness to respond; whereas perceived moral obligation and the belief that nursing students should be encourage to volunteer were positively correlated with willingness to respond.Fire & Emergency Management Administratio

Use of weaning protocols for reducing duration of mechanical ventilation in critically ill adult patients: Cochrane systematic review and meta-analysis

Objective To investigate the effects of weaning protocols on the total duration of mechanical ventilation, mortality, adverse events, quality of life, weaning duration, and length of stay in the intensive care unit and hospital

Lexical-Semantic Abilities of Individuals with Multiple Sclerosis and Aphasia

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Transformation in a changing climate: a research agenda

The concept of transformation in relation to climate and other global change is increasingly receiving attention. The concept provides important opportunities to help examine how rapid and fundamental change to address contemporary global challenges can be facilitated. This paper contributes to discussions about transformation by providing a social science, arts and humanities perspective to open up discussion and set out a research agenda about what it means to transform and the dimensions, limitations and possibilities for transformation. Key focal areas include: (1) change theories, (2) knowing whether transformation has occurred or is occurring; (3) knowledge production and use; (4), governance; (5) how dimensions of social justice inform transformation; (6) the limits of human nature; (7) the role of the utopian impulse; (8) working with the present to create new futures; and (9) human consciousness. In addition to presenting a set of research questions around these themes the paper highlights that much deeper engagement with complex social processes is required; that there are vast opportunities for social science, humanities and the arts to engage more directly with the climate challenge; that there is a need for a massive upscaling of efforts to understand and shape desired forms of change; and that, in addition to helping answer important questions about how to facilitate change, a key role of the social sciences, humanities and the arts in addressing climate change is to critique current societal patterns and to open up new thinking. Through such critique and by being more explicit about what is meant by transformation, greater opportunities will be provided for opening up a dialogue about change, possible futures and about what it means to re-shape the way in which people live

The effect of blood pressure on mortality following out-of-hospital cardiac arrest : a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database

Correction: Volume27, Issue 1 Article Number:169 DOI: 10.1186/s13054-023-04458-x Published: MAY 4 2023Background: Hypotension following out-of-hospital cardiac arrest (OHCA) may cause secondary brain injury and increase mortality rates. Current guidelines recommend avoiding hypotension. However, the optimal blood pressure following OHCA is unknown. We hypothesised that exposure to hypotension and hypertension in the first 24 h in ICU would be associated with mortality following OHCA. Methods: We conducted a retrospective analysis of OHCA patients included in the Intensive Care National Audit and Research Centre Case Mix Programme from 1 January 2010 to 31 December 2019. Restricted cubic splines were created following adjustment for important prognostic variables. We report the adjusted odds ratio for associations between lowest and highest mean arterial pressure (MAP) and systolic blood pressure (SBP) in the first 24 h of ICU care and hospital mortality. Results: A total of 32,349 patients were included in the analysis. Hospital mortality was 56.2%. The median lowest and highest MAP and SBP were similar in survivors and non-survivors. Both hypotension and hypertension were associated with increased mortality. Patients who had a lowest recorded MAP in the range 60-63 mmHg had the lowest associated mortality. Patients who had a highest recorded MAP in the range 95-104 mmHg had the lowest associated mortality. The association between SBP and mortality followed a similar pattern to MAP. Conclusions: We found an association between hypotension and hypertension in the first 24 h in ICU and mortality following OHCA. The inability to distinguish between the median blood pressure of survivors and non-survivors indicates the need for research into individualised blood pressure targets for survivors following OHCA.Peer reviewe

Modality Differences in the Comprehension of Frequency Occurring Nouns and Celebrity Names by Subjects with Aphasia

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The Lynx X-Ray Observatory: Concept Study Overview and Status

Lynx, one of four strategic mission concepts under study for the 2020 Astrophysics Decadal Survey, will provide leaps in capability over previous and planned X-ray missions, and will provide synergistic observations in the 2030s to a multitude of space- and ground-based observatories across all wavelengths. Lynx will have orders of magnitude improvement in sensitivity, on-axis sub-arcsecond imaging with arcsecond angular resolution over a large field of view, and high-resolution spectroscopy for point-like and extended sources. The Lynx architecture enables a broad range of unique and compelling science, to be carried out mainly through a General Observer Program. This Program is envisioned to include detecting the very first supermassive black holes, revealing the high-energy drivers of galaxy and structure formation, characterizing the mechanisms that govern stellar activity - including effects on planet habitability, and exploring the highest redshift galaxy clusters. An overview and status of the Lynx concept are summarized

Synaptopathies: Dysfunction of Synaptic Function Confirmed rare copy number variants implicate novel genes in schizophrenia

Abstract Understanding how cognitive processes including learning, memory, decision making and ideation are encoded by the genome is a key question in biology. Identification of sets of genes underlying human mental disorders is a path towards this objective. Schizophrenia is a common disease with cognitive symptoms, high heritability and complex genetics. We have identified genes involved with schizophrenia by measuring differences in DNA copy number across the entire genome in 91 schizophrenia cases and 92 controls in the Scottish population. Our data reproduce rare and common variants observed in public domain data from >3000 schizophrenia cases, confirming known disease loci as well as identifying novel loci. We found copy number variants in PDE10A (phosphodiesterase 10A), CYFIP1 [cytoplasmic FMR1 (Fragile X mental retardation 1)-interacting protein 1], K + channel genes KCNE1 and KCNE2, the Down's syndrome critical region 1 gene RCAN1 (regulator of calcineurin 1), cell-recognition protein CHL1 (cell adhesion molecule with homology with L1CAM), the transcription factor SP4 (specificity protein 4) and histone deacetylase HDAC9, among others (see http://www.genes2cognition.org/SCZ-CNV). Integrating the function of these many genes into a coherent model of schizophrenia and cognition is a major unanswered challenge