DANOS E RISCOS A EQUIPE DE ENFERMAGEM EM TEMPOS DE PANDEMIA DO COVID-19

Introdução: A pandemia do Covid-19 surgiu como uma doença emergente, no dia 31 de dezembro de 2019, em Wuhan, na China.Durante esse período pandêmico, os profissionais da enfermagem mostraram ser os grandes heróis atuantes na linha de frente,entretanto, essa classe de trabalhadores esteve exposta a variados danos e riscos em suas atividades laborais, impactando direto eindiretamente em sua saúde. Objetivo: descrever quais os riscos e danos que a equipe de enfermagem está exposta em tempos de pandemia, através de uma revisão integrativa. Materiais e Métodos: O presente artigo utilizou 32 artigos, sendo 11 artigos da SCIELO,3 do BDENF, 13 do Google acadêmico e 5 da LILACS. Resultados: A partir da análise de dados, foi possível perceber que houveimpacto na saúde mental dos profissionais de enfermagem, que estavam expostos a fatores de riscos, vulnerabilidade, fragilidade, situações estressantes em suas atividades laborais, devido ao enfrentamento de diferentes desafios impostos pela pandemia do Covid-19. Além disso, foi possível identificar estratégias de enfrentamento, buscadas pela equipe de enfermagem durante a pandemia de COVID-19 e a necessidade de investimentos em programas e estratégias eficientes voltadas a questões psicossociais, acolhimento e apoio emocional dos profissionais de saúde em um cenário pandêmico, pois os mesmos estão suscetíveis ao adoecimento psíquico. Conclusão: Portanto, se faz necessário voltar um olhar cuidadoso às necessidades dos profissionais da enfermagem, que busca por melhorias nas suas condições de trabalho e na remuneração salarial; treinamentos, capacitação adequada; otimização das árduas jornadas de trabalho e reconhecimento.Palavras-chave: Risco ocupacionais. Danos. Enfermagem. COVID-19. Saúde Mental

Factors Related to the Quality of Life in the Context of Deaf Sign Language Users in Brazil

Introduction Deaf sign language users population often has been facing linguistic difficulties regarding to interacting with people who are not aware who have not learnt about using sign language such difficulties may have been revealing serious consequences to their social emotional and also cognitive development Objective This study has aimed to analyze the factors which may be associated with the best scoring of Quality of Life QOL in a group of deaf Brazilian sign language Libras users Methods It is a quantitative study whose data collection has been assessing using the WHOQOL-BREF scale and a sample profile questionnaire as well Sixty 60 deaf Libras users who has been living in Southern region of Brazil have participated Statistical analysis was used by means of descriptive statistical methods and inference methods considering the significance level of 0 05

QUALITY OF LIFE IN DEAF SIGN LANGUAGE USERS IN SOUTHERN BRAZIL PSYCHOLOGICAL DOMAIN

Introduction: Deaf users of Brazilian Sign Language (Libras) constitute part of a population who need to integrate and interact with other people in society. However, many Libras users are not able to communicate through spoken Portuguese and this may have an impact on their quality of life (QoL). Few studies have investigated factors that influence the quality of life of Libras users. Objective: To verify how a group of Libras users, who lives in the South of Brazil, perceive their QoL, especially in the psychological domain. Method: 60 deaf sign language users participated in this study by completing two questionnaires: 1) WHOOQL-BREF instrument in Portuguese written language and/or WHOOQL-Bref - Libras and 2) Identification questionnaire. The research was conducted between, July 2015 February 2016. Results: From the 60 deaf sign language users, 20% were male and 40% female. The mean age was 28 years old, with high school and college education. Overall mean score on WHOOQL-Bref was 43.3%. The Psychological domain have a score (61,26%) Conclusion: Deaf sign language users have low results in the Psychological Domain when compared to hearing people research results. There is association between the results in this domain scores with lack of accessibility and interaction, negative thoughts and depression.  Article visualizations

Estudo sobre Emoções e Sentimentos na Educação Infantil

This study aimed to investigate the role of the pedagogical process on the development of emotions and feelings in the preschool age, based on the analysis of the child’s school activity. This research involved observations in the classroom and an interview with the responsible teacher, in order to analyze the extent to which the pedagogical activities mobilized the emotional aspects of children and contributed to their affective-emotional development. The results showed that being recognized by the teacher in the collective is emotionally more significant than the nature and success of the task execution. It follows that understanding the dynamics of emotions in the concrete school life of pre-school children is essential for pedagogical planning that aim the emancipation of subjects.Este estudo investigou o papel do processo pedagógico sobre o desenvolvimento das emoções e sentimentos na idade pré-escolar, a partir da análise da atividade escolar da criança. A pesquisa envolveu observações em sala de aula e uma entrevista com a professora regente, a fim de analisar em que medida as atividades pedagógicas mobilizavam os aspectos emocionais das crianças e contribuíam para seu desenvolvimento afetivo-emocional. Os resultados demonstraram que ser reconhecido no coletivo pela professora é emocionalmente mais significativo que a natureza e o sucesso da execução da tarefa. Conclui-se que compreender a dinâmica das emoções na vida escolar concreta das crianças em idade pré-escolar é imprescindível para o planejamento pedagógico que vise a emancipação dos sujeitos

Estudo sobre Emoções e Sentimentos na Educação Infantil

This study aimed to investigate the role of the pedagogical process on the development of emotions and feelings in the preschool age, based on the analysis of the child’s school activity. This research involved observations in the classroom and an interview with the responsible teacher, in order to analyze the extent to which the pedagogical activities mobilized the emotional aspects of children and contributed to their affective-emotional development. The results showed that being recognized by the teacher in the collective is emotionally more significant than the nature and success of the task execution. It follows that understanding the dynamics of emotions in the concrete school life of pre-school children is essential for pedagogical planning that aim the emancipation of subjects.Este estudo investigou o papel do processo pedagógico sobre o desenvolvimento das emoções e sentimentos na idade pré-escolar, a partir da análise da atividade escolar da criança. A pesquisa envolveu observações em sala de aula e uma entrevista com a professora regente, a fim de analisar em que medida as atividades pedagógicas mobilizavam os aspectos emocionais das crianças e contribuíam para seu desenvolvimento afetivo-emocional. Os resultados demonstraram que ser reconhecido no coletivo pela professora é emocionalmente mais significativo que a natureza e o sucesso da execução da tarefa. Conclui-se que compreender a dinâmica das emoções na vida escolar concreta das crianças em idade pré-escolar é imprescindível para o planejamento pedagógico que vise a emancipação dos sujeitos

Astrocytes sense glymphatic-level shear stress through the interaction of sphingosine-1-phosphate with Piezo1

Summary: Astrocyte endfeet enwrap brain vasculature, forming a boundary for perivascular glymphatic flow of fluid and solutes along and across the astrocyte endfeet into the brain parenchyma. We evaluated astrocyte sensitivity to shear stress generated by such flow, finding a set point for downstream calcium signaling that is below about 0.1 dyn/cm2. This set point is modulated by albumin levels encountered in cerebrospinal fluid (CSF) under normal conditions and following a blood-brain barrier breach or immune response. The astrocyte mechanosome responsible for the detection of shear stress includes sphingosine-1-phosphate (S1P)-mediated sensitization of the mechanosensor Piezo1. Fluid flow through perivascular channels delimited by vessel wall and astrocyte endfeet thus generates sufficient shear stress to activate astrocytes, thereby potentially controlling vasomotion and parenchymal perfusion. Moreover, S1P receptor signaling establishes a set point for Piezo1 activation that is finely tuned to coincide with CSF albumin levels and to the low shear forces resulting from glymphatic flow

Cell-surface glycosaminoglycans regulate the cellular uptake of charged polystyrene nanoparticles

Engineered nanoparticles approaching the cell body will first encounter and interact with cell-surface glycosaminoglycans (GAGs) before reaching the plasma membrane and becoming internalized. However, how surface GAGs may regulate the cellular entry of nanoparticles remains poorly understood. Herein, it is shown that the surface GAGs of Chinese hamster ovary cells perform as a charge-based barrier against the cellular internalization of anionic polystyrene nanoparticles (PS NPs). In contrast, cationic PS NPs interact favorably with the surface GAGs and thereby are efficiently internalized. Anionic PS NPs eventually reaching the plasma membrane bind to scavenger receptors and are endocytosed by clathrin-mediated and lipid raft/cholesterol-dependent mechanisms, whereas cationic PS NPs are primarily internalized via clathrin-mediated endocytosis and macropinocytosis. Upon the enzymatic shedding of surface GAGs, the uptake of anionic PS NPs increases while that of cationic PS NPs is dramatically reduced. Interestingly, the diminished uptake of cationic PS NPs is observed only when heparan sulfate, but not chondroitin sulfate, is cleaved from the cell surface. Heparan sulfate therefore serves as anchors/first receptors to facilitate the cellular entry of cationic PS NPs. These findings contribute to advance the basic science of nanoparticle endocytosis while also having important implications for the use of engineered nanocarriers as intracellular drug-delivery systems.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)2021/00685-

Emergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection

Brazil, which is hyperendemic for dengue virus (DENV), has had recent Zika (ZIKV) and (CHIKV) Chikungunya virus outbreaks. Since March 2016, CHIKV is the arbovirus infection most frequently diagnosed in Rio de Janeiro. In the analysis of 1835 syndromic patients, screened by real time RT-PCR, 56.4% of the cases were attributed to CHIKV, 29.6% to ZIKV, and 14.1% to DENV-4. Sequence analyses of CHIKV from sixteen samples revealed that the East-Central-South-African (ECSA) genotype of CHIKV has been circulating in Brazil since 2013 [95% bayesian credible interval (BCI): 03/2012-10/2013], almost a year before it was detected by arbovirus surveillance program. Brazilian cases are related to Central African Republic sequences from 1980’s. To the best of our knowledge, given the available sequence published here and elsewhere, the ECSA genotype was likely introduced to Rio de Janeiro early on 2014 (02/2014; BCI: 07/2013-08/2014) through a single event, after primary circulation in the Bahia state at the Northestern Brazil in the previous year. The observation that the ECSA genotype of CHIKV was circulating undetected underscores the need for improvements in molecular methods for viral surveillance.Peer Reviewe

ATLANTIC BIRD TRAITS: a data set of bird morphological traits from the Atlantic forests of South America

Scientists have long been trying to understand why the Neotropical region holds the highest diversity of birds on Earth. Recently, there has been increased interest in morphological variation between and within species, and in how climate, topography, and anthropogenic pressures may explain and affect phenotypic variation. Because morphological data are not always available for many species at the local or regional scale, we are limited in our understanding of intra- and interspecies spatial morphological variation. Here, we present the ATLANTIC BIRD TRAITS, a data set that includes measurements of up to 44 morphological traits in 67,197 bird records from 2,790 populations distributed throughout the Atlantic forests of South America. This data set comprises information, compiled over two centuries (1820–2018), for 711 bird species, which represent 80% of all known bird diversity in the Atlantic Forest. Among the most commonly reported traits are sex (n = 65,717), age (n = 63,852), body mass (n = 58,768), flight molt presence (n = 44,941), molt presence (n = 44,847), body molt presence (n = 44,606), tail length (n = 43,005), reproductive stage (n = 42,588), bill length (n = 37,409), body length (n = 28,394), right wing length (n = 21,950), tarsus length (n = 20,342), and wing length (n = 18,071). The most frequently recorded species are Chiroxiphia caudata (n = 1,837), Turdus albicollis (n = 1,658), Trichothraupis melanops (n = 1,468), Turdus leucomelas (n = 1,436), and Basileuterus culicivorus (n = 1,384). The species recorded in the greatest number of sampling localities are Basileuterus culicivorus (n = 243), Trichothraupis melanops (n = 242), Chiroxiphia caudata (n = 210), Platyrinchus mystaceus (n = 208), and Turdus rufiventris (n = 191). ATLANTIC BIRD TRAITS (ABT) is the most comprehensive data set on measurements of bird morphological traits found in a biodiversity hotspot; it provides data for basic and applied research at multiple scales, from individual to community, and from the local to the macroecological perspectives. No copyright or proprietary restrictions are associated with the use of this data set. Please cite this data paper when the data are used in publications or teaching and educational activities. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ