6 research outputs found
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
- Baba Yabasin Iddrisu
- Babis George
- Bacalbasa Nicolae
- Badiani Sarit
- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
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- Barberis Andrea
- Barbosa-Breda Joao
- Bareka Metaxia
- Barišić Tatjana
- Barlas Aziz Mutlu
- Barlow Ciaran
- Barmayehvar Behrad
- Baroffio Paolo
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- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
- Bashir Mahmod
- Basnayake Oshan
- Bass Gary Alan
- Basu Somprakas
- Bateman Antony
- Bateman Kellie
- Batista Sylvia
- Batstone Martin
- Bauer Marlies
- Bauset Juan Carlos Catalá
- Bawa Ashvind
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- Bayhan Hüseyin
- Bayo Heura Llaquet
- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
- Beisenov Bekzat
- Bellio Gabriele
- Bello Usman Mohammed
- Bellés Ana Ciscar
- Belzile Etienne
- Benamar Safia
- Bence Matthew
- Benshetrit Guy
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- Bergkvist David Julià
- Beristain-Hernandez Jose-Luis
- Bernante Paolo
- Bernardi Daniele
- Beron Reinaldo Isaacs
- Berselli Bruno
- Berselli Mattia
- Bertelli Giacomo
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- Beswick Daniel
- Bette Birgit
- Bezirci Rifat
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- Bharathan Rasiah
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- Bilfaqirah Majed
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- BİŞGİN TAYFUN
- Blair James
- Blanco Jose
- Blencowe Natalie
- Bloemers Frank
- Board Timothy
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- Bohmer Rob
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- Boisson Matthieu
- Boligo Sofia
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- Bondurri Andrea
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- Bonsaana Gilbert Batieka
- Booth L.
- Borg Elaine
- Borges Miguel Fróis
- Borges Nuno
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- Bowen Joel
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- Bramis Konstantinos
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- Bravo Sybil Lizanne
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- Bruzzaniti Placido
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- Cruz Ricardo Pedrini
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- Cullinane Carolyn
- Cullis Paul
- Cunha Miguel F.
- Cunningham Brian
- Currò Giuseppe
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- Cutmore Carina
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- Cáceres Freud
- D'Acapito Fabrizio
- D'Addino José Luis
- D'Amico Alessia
- D'Amore Anna
- D'Andrea Giancarlo
- D'Archi Sabatino
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- Dawson Jonathon
- Dbouk Samer
- De Alarcón Jaime Rodríguez
- De Andrés-Asenjo Beatriz
- De Bacco Marangon Gustavo
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- De Haro Joaquin
- De Jesus Labrador Hernandez Gregorio
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- Djedovic Gabriel
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- Dolci Giampiero
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- Dominguez-Rosado Ismael
- Don Cristine Pathirannehalage
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- Eiras Miguel Angel Freiria
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- Ekwen Gerald
- Ekwunife Okechukwu Hyginus
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- Elbadawy Merihan A.
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- Elnour Moheyaldien Ahmed Elamin
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- Ezenwa Ekene
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- Fahim Margo Medhat Fouad
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- Faponle Folayemi
- Farhan-Alanie Muhamed
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- Farooq Muhammad
- Fatima Mishal
- Fayad Elsayed A.
- Federer Simon
- Federico Nicoletta Sveva Pipitone
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- Gabr Abdullah
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- García Pablo Rodríguez
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- Giacometti Marco
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- Giuffrida Mario
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- Glass Nina
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- Gmati Aimen
- Goel Neha
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- Gollarte Ana Sánchez
- Gomez Eduardo Garcia-Loarte
- Gomez-Fernandez Hugo
- Gomez-Rosado Juan-Carlos
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- Gonzalez Lourdes Elorduy
- Gonzalez Luis Angel Suarez
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- González-Suárez Susana
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- Gosselink Martijn
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- Saleh Ma'Moun
- Salem Hani
- Salem Moacyr
- Salisu Ibrahim
- Salizzoni Stefano
- Sall Ibrahima
- Sallam Asser
- Salunke Pravin
- Salö Martin
- Samadov Elgun
- Saman Pradeep I.H.D.
- Samara Athina
- Samara Evangelia
- Sambhwani Sharan
- Sammour Tarik
- Samo Khursheed Ahmed
- Sandri Giovanni Battista Levi
- Sanli Ahmet Necati
- Santini Alasdair
- Santoro Antonio
- Santos-Costa Paulo
- Santoshi John Ashutosh
- Santric Veljko
- Sapienza Paolo
- Saponaro Gianmarco
- Saraceno Federica
- Saracoglu Ayten
- Saracoglu Kemal
- Sari Ramazan
- Sarjanoja Elise
- Sars Carl
- Sasia Diego
- Sasireka Veerasamy
- Satchithanantham Vinojan
- Satoskar Savni
- Sayed A. Emad
- Sayyed Raza
- Scabini Stefano
- Scacchi Andrea
- Scafa Anthony Kevin
- Scaramuzzo Rosa
- Scaravilli Luca
- Scaringi Stefano
- Schache Andrew
- Schiavone Vincenzo
- Schizas Dimitrios
- Schizas Nikolaos
- Schmitt Françoise
- Schmitz-Rixen Thomas
- Schneck Emmanuel
- Schröder Lars
- Schweitzer Donald
- Scifo Amedeo
- Scopelliti Michele
- Scott Erin
- Seah Kt Matthew
- Sebai Amine
- Seeliger Barbara
- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
- Segaren Nicholas
- Seglenieks Richard
- Segura-Sampedro Juan José
- Seguya Amina
- Seidu Anwar Sadat
- Seiwerth Ingmar
- Sekulić Aleksandar
- Semple Abigail
- Sen Comert
- Senanayake Kithsiri Janakantha
- Senent-Boza Ana
- Seneviratne Sanjeewa
- Senni Carlotta
- Sensi Bruno
- Seraj Shaikh Sanjid
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- Serenari Matteo
- Serra Margherita
- Serra Marta Lopes
- Seshadri Ramakrishnan Ayloor
- Sethi Aman
- Seyfried Steffen
- Seyi-Olajide Justina
- Sečan Tomislav
- Sgarzani Rossella
- Shaban Naseebah
- Shaddad Ebrahim
- Shaerf Daniel
- Shah Faaiz Ali
- Shah Hemina
- Shah Jaffer
- Shah Karishma
- Shah Pritik A
- Shah Vinay
- Shaikh Shafaque
- Shalaby Mostafa
- Shalhoub Joseph
- Shamim Shahzad
- Sharma Naveen
- Sharma Neil
- Sharma Rahul Deo
- Sharma Shilpa
- Sharpin Claire
- Sheen Jonathon
- Shehata Sherif
- Shehta Ahmed
- Sheik Shahila
- Sheikh Eman
- Shekleton Florence
- Shelat Vishal
- Shelmerdine Lauren
- Sherif Ahmed Elshawadfy
- Shiban Ehab
- Shiota Masaki
- Shirazi Ahmed
- Shiwani Haaris
- Shmukler Daniel
- Shokor Muntaser Abu
- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
- Siddig Esra
- Siddiqui M. Tayyab
- Sidiropoulos Theodoros
- Sievers Denise
- Sigamoney Kohila
- Silvestri Vania
- Simoes Joana
- Simon Natalie
- Simoncini Tommaso
- Simões Joana Filipa Ferreira
- Singer Georg
- Singh Abhinav
- Singh Baljit
- Singh Kathryn
- Singh Rajdeep
- Singh Tanveer
- Sinnerton Robert
- Siragusa Leandro
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- Skipworth Richard Je
- Slavchev Mihail
- Sleem Adham
- Smati Ismail
- Smelt Jeremy
- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
- Sorbi Flavia
- Sotiropoulou Maria
- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- Szabómihályová Katarína
- Szakmany Tamas
- Szatmary Peter
- Sztipits Tamás
- Szyluk Karol
- Sá-Marta Eduarda
- Sánchez Alberto Cabañero
- Sánchez Rosa
- Sánchez-Guillén Luis
- Süleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini Nicolò
- Tammo Ömer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
- Tantri Aida Rosita
- Tapia-Herrero Ana-María
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
- Tartaglia Nicola
- Tashkandi Wail
- Taskiran Cagatay
- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- Ulutaş Mehmet Eşref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
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- Valladares Sergio Chávez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Clinical characteristics and outcomes of vaccinated patients hospitalised with SARS-CoV-2 breakthrough infection: Multi-IPV, a multicentre study in Northern Italy
- Author
- Agata Buscemi
- Agnese Comelli
- Alberto Papi
- Alberto Pesci
- Alessandra Bandera
- Alessandra Bandera
- Alessandro Galazzi
- Alessandro Giommi
- Alessandro Nobili
- Alessandro Nobili.
- Alessia Antonella Galbussera
- Alessio Maroccia
- Alice D’Adda
- Alice Fanin
- Alice Vianello
- Andrea Giachi
- Andrea Gori
- Andrea Gori.
- Andrea Gramegna
- Andrea Lombardi
- Andrea Lombardi.
- Angelica Carandina
- Angelo Bianchi Bonomi
- Angelo Rovellini
- Anna Ludovica Fracanzani
- Anna Spolti
- Annalisa Cespiati
- Antonella Caminati
- Antonio Maria Pesenti
- Antonio Muscatello
- Antonio Muscatello
- Antonio Spanevello
- Antonio Vena
- Arianna Liparoti
- Arturo Cerizza
- Barbara Ferrari
- Barbara Vigone
- Benedetta Varisco
- Bianca Veronica Mariani
- Carlo Alberto Peri
- Carlotta Coppola
- Cecilia Azzarà
- Chiara Bellocchi
- Chiara Bobbio
- Chiara Dentone
- Chiara Russo
- Christian Folli
- Cinzia Maria Hu
- Ciro Canetta
- Clara Mandelli
- Costanza Massimo
- Damiano D’Ardes
- Daniele Fumagalla
- Daniele Gabbiani
- Daniele Prati
- Davide Elia
- Davide Mangioni
- Diletta Maira
- Dina Visca
- Domenico Girelli
- Eleonora Tobaldini
- Elisa Fiorelli
- Emanuele Palomba
- Erica Pagliaro
- Ernesto Crisafulli
- Fabiana Busti
- Filippo Billi
- Filippo Sartori
- Flora Peyvandi
- Flora Peyvandi
- Francesca Bai
- Francesca Cherubino
- Francesca Ferarri
- Francesca Vezzani
- Francesco Blasi
- Francesco Cipollone
- Giacomo Grasselli
- Giorgio Bozzi
- Giorgio Colombo
- Giorgio Costantino
- Giovanni Scaglione
- Giulia Colombo
- Giulia Marchetti
- Giulia Renisi
- Giulia Renisi
- Giulia Viero
- Giulia Viero
- Giuliana Fusetti
- Giuseppe Ancona
- Giuseppe Lamorte
- Grazia Eliana Chitani
- Guido Luigi Moreo
- Igor Monti
- Ilaria Beretta
- Ilaria Rossi
- Irena Rota
- Irene De Matteis
- Irene Motta
- Laura Alagna
- Laura Barbetta
- Laura Calcaterra
- Laura Rusconi
- Leonardo Terranova
- Letizia Morlacchi
- Luca Morandi
- Luca Valenti
- Ludovico Furlan
- Luigia Scudeller
- Marco Contoli
- Marco Fava
- Marco Mantero
- Marco Mantero.
- Marco Mussa
- Marco Proietti
- Marco Vicenzi
- Margherita Ori
- Maria Manunta
- Maria Pappalettera
- Maria Teresa Guagnano
- Marianna Rossi
- Mariele Passarella
- Marta Biondan
- Marta Colaneri
- Marta Di Pasquale
- Marta Mancarella
- Martina Contarini
- Matteo Bassetti
- Matteo Bolis
- Matteo Cesari
- Maura Spotti
- Mauro Tettamanti
- Mauro Tettamanti
- Michele De Caro
- Mirta Cavallini
- Monica Solbiati
- Nadia Boasi
- Natalia Scaramellini
- Nathalie Iannotti
- Nicholas Battistini
- Nicola Montano
- Paola Faverio
- Paola Saltini
- Paolo Bonfanti
- Pasqualina Iannuzzi
- Raffaella Rossio
- Riccardo Ungaro
- Roberta Gualtierotti
- Roberta Massafra
- Roberto Cassandro
- Rosa Lombardi
- Rosaria Bianco
- Sara Leone
- Serena Ludovisi
- Sergio Harari
- Silvano Bosari
- Silvia Accordino
- Silvia Della Fiore
- Silvia Dell’Orto
- Silvia Giovannelli
- Simona Biscarini
- Simone Villa
- Sofia Misuraca
- Stefano Aliberti
- Stefano Zucchetti
- Teresa Itri
- Tiziano Lucchi
- Toussaint Muheberimana
- Valentina Ferroni
- Valeria Bono
- Valeria Castelli
- Valeria Pastore
- Valeria Rossetti
- Valerie Melli
- Valter Monzani
- Publication venue
- Elsevier
- Publication date
- 01/03/2024
- Field of study
Background: Despite the well-known efficacy of anti-COVID-19 vaccines in preventing morbidity and mortality, several vaccinated individuals are diagnosed with SARS-CoV-2 breakthrough infection, which might require hospitalisation. This multicentre, observational, and retrospective study aimed to investigate the clinical characteristics and outcomes of vaccinated vs. non-vaccinated patients, both hospitalised with SARS-CoV-2 infection in 3 major hospitals in Northern Italy. Methods: Data collection was retrospective, and paper and electronic medical records of adult patients with a diagnosed SARS-CoV-2 infection were pseudo-anonymised and analysed. Vaccinated and non-vaccinated individuals were manually paired, using a predetermined matching criterion (similar age, gender, and date of hospitalisation). Demographic, clinical, treatment, and outcome data were compared between groups differing by vaccination status using Pearson’s Chi-square and Mann-Whitney tests. Moreover, multiple logistic regression analyses were performed to assess the impact of vaccination status on ICU admission or intra-hospital mortality. Results: Data from 360 patients were collected. Vaccinated patients presented with a higher prevalence of relevant comorbidities, like kidney replacement therapy or haematological malignancy, despite a milder clinical presentation at the first evaluation. Non-vaccinated patients required intensive care more often than their vaccinated counterparts (8.8% vs. 1.7%, p = 0.002). Contrariwise, no difference in intra-hospital mortality was observed between the two groups (19% vs. 20%, p = 0.853). These results were confirmed by multivariable logistic regressions, which showed that vaccination was significantly associated with decreased risk of ICU admission (aOR=0.172, 95%CI: 0.039–0.542, p = 0.007), but not of intra-hospital mortality (aOR=0.996, 95%CI: 0.582–1.703, p = 0.987). Conclusions: This study provides real-world data on vaccinated patients hospitalised with COVID-19 in Northern Italy. Our results suggest that COVID-19 vaccination has a protective role in individuals with higher risk profiles, especially regarding the need for ICU admission. These findings contribute to our understanding of SARS-CoV-2 infection outcomes among vaccinated individuals and emphasise the importance of vaccination in preventing severe disease, particularly in those countries with lower first-booster uptake rates
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
- Author
- Abrate Paolo
- Accordino Silvia
- Ageno Walter
- Agnoletti Vanni
- Agosti Michele
- Agostini Carlo
- Agostini Moreno
- Agostinone Adriana
- Agrati Antonio Maria
- Aiello Giuseppe
- Aiuti Massimo
- Albano Giovanni
- Alberico Marielisa
- Alborghetti Armando
- Alborghetti Leonardo
- Aldegheri Giorgio
- Allevi Elisabetta
- Amadasi Silvia
- Amaglio Angelo
- Amitrano Maria
- Amoroso Filippo
- Andrea Antonini
- Andrea Bellone
- Andreassi Silvia
- Andreoni Massimo
- Angarano Gioacchino
- Angeletti Chiara
- Angelici Stefano
- Angheben Andrea
- Angileri Manuela
- Angrisani Claudio
- Annnunziata Maria Laura
- Annunziata Anna
- Anselmo null
- Ansuini Andrea
- Antivalle Marco
- Antonio Fioravanti
- Antonioli Chiara Maria
- Aondio Gianmarco
- Appiani Camilla
- Aquilini Donatella
- Arcidiacono Antonio
- Arcoleo Giuseppe
- Arenare Laura
- Arenare Laura
- Argilloni Elena
- Ariani Alarico
- Arlotti Massimo
- Artiol Stefania
- Artoni Paola Daniela
- Ascierto Paolo Antonio
- Ascierto Paolo Antonio
- Ashofarir Najat
- Atripaldi Luigi
- Atripaldi Luigi
- Atteno Mariangela
- Babudieri Sergio
- Baccari Laura
- Baciu Izabela
- Badagliacca Rita
- Bakhtadze Nikoloz
- Baldessari Chiara
- Ballarin Andrea
- Ballotta Andrea
- Bandiera Francesco
- Banfi Elisa
- Baratta Alberto
- Barattini Massimo
- Baratto Fabio
- Barbato Valentina
- Baré Cristina
- Barone Antonietta
- Baroni Irene
- Baronio Barabara
- Barreca Filippo
- Bartolaminelli Clara
- Barzan Daniela
- Basile Adriano
- Bassetti Matteo
- Bassi Flavio
- Battistini Nicholas
- Bausi Simona
- Bella Anna Maria
- Bellan Mattia
- Bellintani Claudio
- Bellinzona Guido
- Bellucci Francesco
- Belsito Agata
- Beltrame Angela
- Beltramini Sabrina
- Belvisi Valeria
- Benatti Elisa
- Benatti Francesco
- Benedetti Valentina
- Benigni Giovanni
- Beretta Flavio Niccolò
- Berlendis Marialma
- Berlot Giorgio
- Bernardi Cristina
- Bernardi Enrico
- Bernardi Livio
- Bernardi Paola
- Bernasconi Mara
- Bernhart Othmar
- Bertellini Elisabetta
- Berté Ylenia
- Bertoldi Marco
- Bettazzi Laura
- Bettega Donato
- Bettini Daniela
- Bevilacqua Simona
- Beyene Nebiat Balei
- Bezzi Michela
- Bianchetti Angel
- Bianchi Attilio Antonio Montano
- Bianchi Cristina
- Bianchi Michele
- Bianchin Andrea
- Bianco Antonella
- Bianco Vincenzo
- Bina Niccolò
- Binda Francesca
- Binda Francesca
- Bindoli Sara
- Bini Francesco
- Biondi Andrea
- Bisio Claudia
- Bitetto Michele
- Bitti Giuseppina
- Bizzotto Giada
- Blanc Pierluigi
- Blanzuoli Laura
- Blasi Livio
- Boari Gianluca Edoardo Mario
- Boccalatte Daniela
- Boccasile Laura
- Bocchi Federica
- Bocchi Pietro
- Boglione Lucio
- Bokor Daniela
- Bonazzi Maurizio
- Bonetti Silvia
- Bonfante Salvatore
- Bonfanti Paolo
- Bonfanti Paolo
- Boni Fabrizio
- Boni Sabrina
- Bonifazi Marina
- Bonizzoli Manuela
- Bonizzoli Mnuela
- Boracchia Luca
- Bordignon Susanna
- Bordonali Alessandro
- Borghetti Paolo
- Borroni Vittorio
- Boschi Andrea
- Bosco Enrico
- Bosco Francesca
- Bossini Nicola
- Bottalico Irene
- Bottega Roberta
- Botti Gerardo
- Botti Gerardo
- Bottiroli Maurizio
- Bottoli Maria Grazia
- Bovetto Elena
- Bragantini Damiano
- Bragazzi Maria Consiglia
- Brancaleoni Paolo
- Bravi Stefania
- Bravi Stefano
- Brentana Loretta
- Bretto Cristina
- Brianti Annalisa
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- Brocchieri Alessandra
- Brollo Lucio
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- Bruno Raffaele
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- Buonomo Antonio Riccardo
- Bussini Linda
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- Buzzigoli Stefano
- Cabrini Luca
- Cacopardo Bruno
- Caimi Marina
- Calabria Giosuè
- Calcagno Andrea
- Caldini Eleonora
- Calleri Guido
- Calvi Rovberta
- Calzetti Carlo
- Calzetti Carlo
- Camarda Gaetana
- Camici Laura
- Caminati Antonella
- Caminiti Giulia
- Campagna Giuseppe
- Campomori Annalisa
- Cancanelli Luca
- Canetta Ciro
- Cannizzo Stefania
- Canta Francesca
- Cantadori Luca
- Canzanella Giuliana
- Capici Serena
- Capitanio Chiara
- Caporusso Rosa Roberta
- Cappelli Carlo
- Cappi Cinzia
- Capuozzo Antonio
- Caputo Anna Maria
- Carai Antonina
- Carbonara Sergio
- Carbone Giorgio
- Carbonelli Cristiano Matteo
- Cardinale Vincenzo
- Cardone Claudia
- Cardone Claudia
- Caria Federico Carlo
- Carletti Massimo
- Carli Tiziana
- Carlotto Antonio
- Carpinteri Giuseppe
- Carpinteri Maurilio
- Carraro Anna
- Cartella Stefania
- Carubia Giulia
- Caruso Andrea
- Caruso Maria Grazia
- Casadio Lorenzo
- Casati Giorgio
- Casati Giovanni
- Cascella Marco
- Casella Giampaolo
- Casella Orazio
- Casella Silvia
- Casinelli Katia
- Castellan Andrea
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- Castelli Francesco
- Castelli Francesco
- Castellini Mariateresa
- Castello Luigi
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- Castenetto Enzo
- Castiglione Giacomo
- Catalano Filippo
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- Cattaneo Alessandra
- Cattaneo Paolo
- Cattaneo Sergio
- Cattelan Anna Maria
- Cauda Roberto
- Cavanna Luigi
- Cazzaniga Marina
- Celesia Benedetto Maurizio
- Celeste Mariagrazia
- Cemuschi Alessandra Maria
- Cerbo Lidia
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- Cerutti Alessandro
- Cerutti Elisabetta
- Cesareo Roberto
- Cesira Nencioni
- Cettolo Francesca
- Cherubini Antonio
- Chiarello Tosca
- Chiari Silvia
- Chiereleson Francesco
- Chierico Katiuscia
- Chiesa Elena
- Chinello Pierangelo
- Chiodelli Giulia
- Chiodini Paolo
- Chiodini Paolo
- Chiumiento Fernando
- Ciani Silvia
- Ciarrochi Erika
- Ciccone Antonello
- Ciccullo Arturo
- Cicognini Daniela
- Cimolato Barbara
- Cinnella Gilda
- Ciofetti Morena
- Cioni Giorgio
- Cipolla Giuseppe
- Cipollone Francesco
- Cirasa Maria Teresa
- Cirillo Fernanda
- Cirri Silvia
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- Ciuffreda Marcello
- Civita Marina
- Claudio Norbiato
- Clementi Stefano
- Clerici Raffaella
- Clini Enrico
- Cocchi Silvia
- Cocco Livio
- Codeluppi Mauro
- Cogi Enrico
- Cola Luisanna
- Columpsi Paola
- Conforti Francesco
- Consales Guglielmo
- Consorte Augusta
- Converso Marcella
- Coppola Marina
- Coppola Nicola
- Corcione Silvia
- Corda Luciano
- Corridi Marta
- Corsaro Annamaria
- Corsini Romina
- Corso Luisella
- Corvini Federica
- Cosentino Carmine
- Cosimo Franco
- Cosseta Daniele
- Cossu Maria Vittoria
- Costa Chiara
- Costa Isabella
- Costa Raffaella
- Costantini Massimo
- Costantini Paolo
- Covesnon Maria Grazia
- Cozzio Susanna
- Crapis Massimo
- Crepaldi Monica
- Crespi Stefano
- Crespi Tiziano
- Crippa Ilaria Alice
- Crippa Massimo
- Crisafulli Ernesto
- Cristiana Seravalle
- Cristina Zocchetti
- Cristini Francesco
- Criveller Pietro
- Croci Leonardo
- Cuppone Maria Teresa
- Curtolo Ambrogio
- Curvietto Marcello
- Cuzzone Vincenzo
- Dagna Lorenzo
- Dalbeni Andrea
- Dalè Michael
- Damiani Carla
- Damiano Terenzio
- Daniele Antonio
- Daniele De Nardo
- Daniele Italiani
- Danieli Elisabetta
- Danzi Maria
- Dasseni Nicola
- David Marco
- De Almeida Neves Naile
- De Arroyabe Blanca Martinez Lopez
- De Candia Daniele
- De Caro Monica
- De Conti Fabio
- De Cristoforo Maria Giovanna
- De Donno Giuseppe
- De Feo Gianfranco
- De Filippi Claudia
- De Franco Daniela
- De Gennaro Fabio
- De Luca Silvana
- De Marco Mario
- De Masi Margherita
- De Matteis Giovanni
- De Michele Fausto
- De Monte Andrea
- De Negri Pasquale
- de Paduanis Giovanna Attilia
- De Palma Raffaele
- De Ponti Simona
- De Rosa Annunziata
- De Rosa Francesco
- De Rosa Francesco Giuseppe
- De Stefano Giulio
- De Struppi Silvia
- De Vito Andrea
- Deidda Silvia
- Dejaco Christian
- Del Bono Valerio
- Del Borgo Cosmo
- del Duca Sara
- Del Fabbro Roberto
- Del Giudice Antonia
- Del Giudice Emanuela
- Del Prete Maria Simona
- Del Punta Veronica
- Del Vecchio Rosa Fontana
- Delfanti Fanny
- Delfrate Nichola Walter
- Delliponti Mariangela
- Dell’Aquila Giuseppina
- dell’Ara Francesca
- Dell’uomo Vanessa
- Delmonte Vito
- Delnero Pietro
- Delucchi Maurizio
- Dennetta Donatella
- Dentali Francesco
- Desiderio Emilia
- Di Biase Valeria
- Di Carlo Anna Maria
- Di Carlo Marco
- Di Caterino Emilio
- Di Cato Luca
- Di Cura Villa Giada Pallotti Casa
- Di Filippo Alessandro
- di Grigoli Paola
- Di Lorenzo Andrea
- Di Nunzio Camilla
- Di Perna Felicia
- Di Perri Giovanni
- Di Pietro Massimo Antonio
- Di Rosa Zaira
- Di Rosolini Maria Antonietta
- Di Sanzo Daniela
- Di Sciacca Riccardo
- Di Stefano Daniela Emanuela
- Di Stefano Michele
- Diberardino Stefania
- Dognini Giuseppina
- Dolci Giovanni
- Dolci Giovanni
- Dolfini Viola
- Donati Luca
- Donghi Lorenzo
- Donne Livia Delle
- Donno Davide R.
- Doria Andrea
- Dorina Balan
- Dragonetti Maria Margherita
- Drera Monica
- D’Abraccio Maurizio
- D’Alagni Giancarlo
- D’amico Federico
- D’amico Maria
- D’Andrea Giovanna
- D’offizi Gianpiero
- Ebbreo Gabriele
- Eisendle Frederik
- Enrica Caviglia
- Equitani Francesco
- Ercolino Giovanna
- Erne Elke Maria
- Espinosa Emma
- Esposito Vincenzo
- Fabbri Camilla
- Fabietti Paolo
- Fabio Toffoletto
- Facchini Cesarina
- Faccio Luciana
- Facciolongo Nicola Cosimo
- Facondini Francesca
- Fadda Andrea
- Faggioli Paola
- Fancoli Fabiana
- Faoro Sonia
- Fara Claudio
- Farina Antonella
- Farina Martina
- Farinazzo Maddalena
- Fasolo Martina
- Favero Vittoria
- Felicietti Mara
- Fendt Doris
- Ferrante Patrizia
- Ferrara Maurizio
- Ferrari Alessandra
- Ferrari Alessandro
- Ferrari Davide
- Ferrari Luisella
- Ferraris Laurenzia
- Ferraris Laurenzia
- Ferreri Enrico
- Ferrero Giovanna
- Fiammengo Fabio
- Fico Lorenzo
- Filippelli Amelia
- Filippini Matteo
- Filtz Annalisa
- Fiorentino Giuseppe
- Fiorini Barbara
- Fiscon Marta
- Flocco Romeo
- Flores Kristoffer
- Florio Manuela
- Focà Emanuele
- Fondaco Laura
- Fontana Costantino
- Fontana Matteo
- Foresta Giancarlo
- Fornaro Giacomo
- Fraganza Fiorentino
- Fraganza Fiorentino
- Franceschini Franco
- Francesco Claudio
- Francesco Lemut
- Franchi Federico
- Francisci Daniela
- Francisco Chiara
- Franco Antonina
- Franzetti Fabio
- Frascati Andrea
- Frattari Antonella
- Frausini Gabriele
- Fregoni Vittorio
- Frigerio Sillia
- Frigieri Francesca Covani
- Froldi Marco
- Fronti Elisa
- Fumagalli Roberto
- Furiani Silvia
- Furino Ermenegildo
- Fusar Maurizio
- Fusco Francesco Maria
- Fusco Pierluigi
- Gabriele Frausini
- Gaggiotti Mario
- Gaglio Leonardo
- Gaglione Gianfranco
- Galante Dario
- Galati Vincenzo
- Galderisi Feliciano
- Gallazzi Chiara
- Gallo Andrea
- Gallo Ciro
- Gallo Ciro
- Gallotti Pietro
- Gandino Anna
- Gardellini Angelo
- Gargiulo Piera
- Gargiulo Piera
- Gasparini Stefano
- Gasperini Beatrice
- Gatti Francesca
- Gatti Pietro
- Gaudiano Gianfranco
- Gazzola Lisa
- Gazzola Ospedale Erika
- Gelormini Domenico
- Generali Daniele
- Gennarini Silvia
- Genovese Elvira
- Gentile Ivan
- Gentili Vincenzo
- Gentilini Claudio
- Germanà Giuseppe
- Ghidoni Giulia
- Ghirardi Gianluca
- Ghirardi Leonardo
- Ghiringhelli Paolo
- Giachi Andrea
- Giacomazzi Francesca
- Giacomini Matteo
- Gianelli Davide
- Giannandrea Giusy
- Giannelli Luciana
- Giannotti Michella
- Giglio Omar
- Gilberto Fiore
- Gilio Michele
- Gilioli Fabio
- Ginanni Roberta
- Gioacchini Maria Teresa
- Giogré Giuseppina
- Gioia Stefania
- Giorgi Riccardo
- Giorgis Silvia
- Giovanni Cenderello
- Gipponi Paola
- Girardis Massimo
- Girelli Domenico
- Girolimetti Rita
- Giubellino Elena
- Giuseppe Lain
- Giustinetti Giulia
- Gnesin Paolo
- Gnessi Camillo
- Gnudi Umberto
- Gobbo Giulia
- Gori Daniela
- Gori Gianluca
- Gottin Leonardo
- Granata Maria Luisa
- Grassi Walter
- Grasso Ilaria
- Gravina Adriano
- Gravina Adriano
- Graziosi Camilla
- Greco Antonio
- Greco Stefano
- Grio Michele
- Grisolia Antoenlla
- Gritti Giuseppe
- Grossi Paolo Antonio
- Guadagnin Maria Licia
- Guaraldi Giovanni
- Guarino Salvatore
- Guarneri Luigi
- Guelfi Paolo
- Guerini Fabio
- Guerra Alberto
- Guerrini Giulio
- Gugliemi Gaspare
- Guidelli Giacomo Maria
- Guidi Maria Francesca
- Gulisano Leonardo
- Harari Sergio
- Henchi Sonia
- Hofer Alex
- Iacobello Carmelo
- Iemoli Enrico
- Iengo Bianca
- Ilaria Blangetti
- Imitazione Pasquale
- Imperiale Daniele
- Inchiostro Sandro
- Infantino Gessica
- Inglese Francesco
- Ingrosso Marco
- Innocenti Giorgio
- Iommelli Chiara
- Ippoliti Giovanbattista
- Isgrò Valentina
- Iuorio Angela
- Jocollé Genny
- Kertusha Blerta
- Kokaly Francesco
- Labate Demetrio
- Labella Daniela
- Lacedonia Donato
- Lambertenghi Lorenza
- Lamonica Silvia
- Lancione Luca
- Landi Raffaella
- Landini Giancarlo
- Lanfranco Maurizio
- Langer Thomas
- Larussa Dora
- Latronico Nicola
- Lavoretano Sabrina
- Lavorini Federico
- Lazzeri Chiara
- Leone Armando
- Leonetti Frida
- Leto Gaetano
- Liberato Nicola Lucio
- Liccardi Marco Maria
- Lichtner Miriam
- Lichtner Miriam
- Lilli Marianna
- Lingua Anna
- Lipani Filippo
- Lipari Alessio
- Liparulo Luigi
- Liuzzi Nicola
- Livigni Sergio
- Lo Caputo Sergio
- Lonati Veronica
- Lorenzotti Silvia
- Losappio Ruggero
- Lubrano Giuseppe
- Lubrano Riccardo
- Luca Boracchia
- Lucci Antonella
- Lucernoni Paolo
- Luchi Sauro
- Lui Stefania
- Lutri Lorenzo
- Maccari Daniela
- Macheda Sebastiano
- Machiavelli Andrea Marco
- Madeddu Giordano
- Maffezzini Elena
- Maffongelli Gaetano
- Maggi Paolo
- Maggioni Paola
- Magnaca Andrea
- Magni Marta
- Magrini Stefano
- Magro Gaetano
- Mahlknecht Klaus
- Maietta Pasquale
- Maimone Patrizia
- Mainardi Stefano
- Malberti Fabio
- Malcontenti Costanza
- Malena Marina
- Malgorzata Mikulska
- Mancini Annalisa
- Mancini Mauro
- Mandelli Anna
- Manfredini Elena
- Manfrin Vinicio
- Mangano Carmelo
- Mangiacapra Sara
- Manini Alessandra
- Manini Arianna
- Manno Emilpaolo
- Mantovani Barbara
- Mantovani Lorenzo Filippo
- Manuele Rosa
- Manzi Andrea
- Manzillo Elio
- Maraolo Alberto
- Marata Anna Maria
- Marchesoni Ivan
- Marchetti Giulia
- Marchetti Valentina
- Marchi Maria Rita
- Marco Baiocchi
- Marcon Elisabetta
- Mariani Roberta
- Marinangeli Franco
- Marinelli Alfredo
- Marini Enrico
- Marini Sara Francesca
- Marino Andrea
- Marino Francesco
- Marino Pietro
- Maroccia Alessio
- Marocco Raffaella
- Maroni Lorenzo
- Marra Lorenzo
- Marrazzo Gerarda
- Marrocco Francesca
- Marrocco-Trischitta Massimiliano M.
- Marrocco-Trischitta Massimiliano M.
- Martelli Domenico
- Martellucci Salvatore
- Martinelli Laura
- Martino Giuseppe Pio
- Martino Marilena
- Masolin Tiziana
- Maspero Sonia
- Massari Marco
- Massari Marco
- Masserini Federico
- Mastroianni Alessandro
- Mastroianni Antonio
- Mastroianni Claudio
- Mastroianni Claudio Maria
- Mastroianni Franco
- Mastropasqua Bernardino
- Masullo Alfonso
- Matei Anaflorina
- Matsuno Jun Sebastian
- Mauro Immacolata
- Mazzola Francesca
- Mazzola Giovanni
- Mazzoleni Manuel
- Mazzone Antonino
- Mecozzi Alessandra
- Mei Federico
- Meli Alessandro
- Meliante Piero Giuseppe
- Melica Tiziana
- Mencarini Jessica
- Mengoli Caterina
- Menicacci Lorenzo
- Menicanti Lorenzo
- Mensi Giulio
- Mercurio Vito Sante
- Meschi Tiziana
- Meschiari Marianna
- Meschini Carlo
- Messina Antonio
- Messina Florinda
- Messina Vincenzo
- Metra Marco
- Micarelli David
- Miceli Marco
- Michieletto Lucio
- Mietta Sabrina
- Mighali Pasquale
- Migliori Lucia
- Milia Mario
- Mina Federica
- Minato Milena
- Minelli Enrica
- Minoja Guja
- Minuz Pietro
- Miscio Leonardo
- Modica Sara
- Molaro Raffaele
- Molino Paola
- Mollica Mariano
- Molteni Alfredo
- Molteni Chiara
- Momesso Elena
- Monacci Cecilia
- Mondino Michele
- Mondino Vincenzo
- Moneta Sara
- Monforte Antonella D’arminio
- Montagnini Francesca
- Montalto Maria Teresa
- Montani Giovanni
- Monteforte Gabriella
- Montemurro Lidia
- Montesarchio Vincenzo
- Montesarchio Vincenzo
- Monti Roberto
- Monticelli Jacopo
- Montineri Arturo
- Montisci Andrea
- Montrucchio Chiara
- Morando Giovanni
- Morbidoni Laura
- Morettini Alessandro
- Morgana Gianfranco
- Moroni Alice
- Moroni Carlo
- Moroni Federico
- Mosca Giacomo
- Moschini Greta
- Mosti Silvia
- Motta Leonardo
- Mucci Luciano
- Muiesan Maria Lorenza
- Muiesan Maria Lorenza
- Murdaca Giuseppe
- Mussini Cristina
- Mussini Cristina
- Musumeci Diana
- Muttini Stefano
- Nallino Gabriella
- Napoli Giovanna
- Nardecchia Anna Laura
- Nardi Stefano
- Nasta Paola
- Nava Antonella
- Nava Valeria
- Navalesi Paolo
- Navarra Mauro
- Negri Emanuele Alberto
- Negri Emanuele Alberto
- Negro Cristina
- Negro Enrica
- Nespola Giorgio Amadio
- Nicastri Emanuele
- Nico Andrea
- Nicolini Laura Ambra
- Nijhawan Parni
- Niro Dario
- Nonini Sandra
- Noto Concetta
- Nouvenne Antonio
- Novali Mauro
- Nucera Antonia
- Nucera Gabriella
- Nuceri Antonia
- Numis Fabio Giuliano
- Odolini Silvia
- Oggionni Tiberio
- Olivetti Alessandro
- Omega Luca
- Oppedisano Peppino
- Orlandi Matteo
- Ornella Calderone
- Otero Manuela
- Ottaviano Mario
- Pace Erminio
- Pacentra Enrico
- Pacetti Veronica
- Pagani Silvia
- Pagliano Pasquale
- Pagnoni Carlo
- Pagnozzi Fiammetta
- Paini Anna
- Palagano Nicolas
- Palla Marco
- Palladino Marcello
- Pallotto Carlo
- Palmieri Fabrizio
- Palmiero Gerardo
- Palmiotti Giuseppe Antonio
- Palumbo Michele
- Pampaloni Alessio
- Panaccione Anna
- Pandini Chiara Stefania
- Panese Sandro
- Panico Rosanna
- Pannella Greta
- Panzolato Gianluigi
- Paone Tonia Celeste
- Papetti Claudia
- Papi Alberto
- Para Ombretta
- Parrella Roberto
- Parrella Roberto
- Parrocchia Sergio
- Parruti Giustino
- Pascale Renato
- Pasero Daniela
- Pasini Simone Marino
- Pasquini Zeno
- Pasquino Bernadetta
- Pasquino Paola
- Passalacqua Rodolfo
- Pastorelli Mauro
- Pasulo Luisa
- Pavei Chiara
- Pavoni Vittorio
- Peci Paolo
- Pedrini Luciano
- Pelagatti Lorenzo
- Pensa Anna
- Pepe Antonio
- Perego Giovanni Battista
- Peregrinelli Alessio
- Perfetti Elisa
- Perin Tiziana
- Peris Adriano
- Perra Roberto
- Perrone Francesco
- Perrone Francesco
- Perugini Orietta
- Pesce Laura
- Petrone Anna
- Petrosillo Nicola
- Piazza Manuela
- Piazza Ornella
- Piccinni Rosangela
- Piccirillo Maria Carmela
- Piccirillo Maria Carmela
- Piccoli Jolanda
- Piconi Stefania
- Pieralli Filippo
- Pierantozzi Silvia
- Pierfranceschi Matteo Giorgi
- Pierini Simona
- Pietrangelo Antonello
- Piga Sandro
- Pignatti Andrea
- Piluso Martina
- Pinelli Giovanni
- Pinna Simone Mornese
- Pirozzi Maria Rosa
- Pisapia Raffaella
- Pisterna Alessia
- Pitagora Loredana
- Piva Simone
- Plamieri Giulia
- Poggesi Loredana
- Pognuz Erik Roman
- Poisa Paolo
- Polati Enrico
- Poletti Enrico
- Poletti Venerino
- Poli Federica
- Poli Marco Dei
- Polistina Giorgio
- Pollastri Costanza
- Pontali Emanuele
- Ponticiello Antonio
- Pontiggia Silvia
- Pontremoli Roberto
- Popoli Patrizia
- Porta Francesca Della
- Porta Giovanni
- Portale Grazia
- Potenza Domenico
- Prandini Paolo
- Presotto Fabio
- Prestini Katiela
- Principi Tiziana
- Properzi Martina
- Prozzo Alessandra
- Pulitanò Grazia
- Pulvirenti Fabrizio
- Punzi Rodolfo
- Puorto Antonella
- Puoti Massimo
- Pusterla Luigi
- Puttini Camilla
- Quadri Rachele Delli
- Racagni Milena
- Raffaeli Davide
- Raffaelli Valentina
- Raimondo Mariangela
- Rampa Lorenzo
- Ranghitta Melania
- Ranucci Marco
- Rapisarda Giuseppe
- Raponi Gianna
- Rastelli Gianni
- Rastellino Valentina
- Raumer Luigi
- Ravaglia Claudia
- Ravagnani Viviana
- Ravani Serena
- Regazzetti Angelo
- Reghenzi Piera
- Regis Monica
- Repossi Alice
- Rescigno Carolina
- Resimini Silvia
- Resta Marco
- Reta Massimo
- Ribecco Maria Teresa
- Riccardi Ferdinando
- Riccardi Niccolò
- Ricchiardi Alberto
- Ricci Chiara
- Ricci Clara
- Ricci Maria Anastasia
- Ricci Massimo
- Ricci Silvano
- Riccio null
- Ricioppo Aristodemo
- Ridola Lorenzo
- Riggio Oliviero
- Righetti Giulia
- Righini Erminio
- Ripamonti Diego
- Ripamonti Diego
- Rivitti Rosario
- Rizzardini Giuliano
- Rizzi Eleonora
- Rizzoni Damiano
- Roberti Giuseppe
- Roccaro Aldo
- Roccatello Dario
- Rocchetti Chiara
- Rocco Monica
- Roldan Eugenia Quiros
- Romagnoli Micaela
- Romanelli Michela
- Romano Anacleto
- Romano Annamaria
- Romano Fiorella
- Romeo Domenico
- Romeo Francesca
- Roncaglia Enrica
- Ronconi Maurizio
- Rossati Antonella
- Rossetti Barbara
- Rossi Alberto
- Rossi Nicolò
- Rossini Tizana
- Roveda Elena
- Rovere Pierangelo
- Ruggeri Ruggero
- Ruggieri Annamaria
- Ruggieri Lorenzoa
- Ruggieri Maria Paola
- Russo Chiara
- Russo Gianluca
- Russo Grazia
- Russo null
- Russo Roberto
- Rutili Maria Serena
- Sabato Eugenio
- Sabatti Maria Cecilia
- Sachs Michele
- Saffioti Carolina
- Saglimbene Sebastiana
- Sainaghi Pier Paolo
- Sala Girolamo
- Sala Luca
- Sala Nadia
- Salerno Anna Maria
- Salerno Nicola Duccio
- Salerno Nicola Duccio
- Salsi Pierpaolo
- Saltori Martino
- Salvarani Carlo
- Salvarani Carlo
- Salvetti Massimo
- Sangiovanni Antonella
- Sangiovanni Vincenzo
- Santantonio Teresa Antonia
- Santilli Giuseppina
- Santini Luca
- Santoboni Gianluca
- Santopuoli Donato
- Santoro Armando
- Saracco Marta
- Saracino Annalisa
- Sarmati Loredana
- Sarni Antonella
- Sarteschi Giovanni
- Sartori Enrico
- Satira Roberto
- Savi Maria Laura
- Savio Alfonso
- Savio Maria Cristina
- Sbreglia Costanza
- Scabini Silvia
- Scaglione Nadia
- Scala Alberto
- Scalabrino Elisa
- Scapino Bruno
- Scarafino Antonio
- Scarano Francesco
- Scartabellati Alessandro
- Schettino Clorinda
- Schettino Clorinda
- Schettino Giuseppe
- Scimonello Guglielmo
- Sciolè Katiuscia
- Scolari Francesco
- Scollet Sabino
- Scorletti Eva
- Scotto Riccardo
- Scotton Pier Giorgio
- Scozzafava Mariano
- Scudellari Roberta
- Sdanganelli Antonia
- Sellitto Carmine
- Sepulcri Chiara
- Serao Mattia
- Serati Lisa
- Serino Francesco Saverio
- Serra Eugenio
- Servillo Giuseppe
- Sgarabotto Camilla
- Sicheri Domenico
- Sighieri Cinzia
- Silengo Daniela
- Silva Matteo
- Silvia Tamanini
- Sirignano Emanuele
- Sorrentino Carlo
- Sortino Claudio
- Spadoni Claudia
- Spagnolli Walter
- Spagnuolo Giovanni
- Spanu Paolo
- Sparavigna Lucia
- Spatafora Mario
- Spatarella Micaela
- Spaziani Sandra
- Spina Rosario
- Spinicci Michele
- Spizzo Gilbert
- Spolveri Stefano
- Sportato Giuseppe
- Squillace Nicola
- Squillace Nicola
- Stefanetto Ivana Marina
- Stellini Roberto
- Stillante Maria Serafina
- Stobbione Paolo
- Storti Angelo
- Storti Enrico
- Straface Giuseppe
- Strano Giuseppe
- Stroppa Elisa Maria
- Suardi Lorenzo Roberto
- Succu Angela
- Tacconelli Evelina
- Tacconi Danilo
- Tafuri Agostino
- Taglietti Fabrizio
- Taibi Chiara
- Tarquini Giovanna
- Tarsia Paolo
- Tasca Francesca
- Tebaldi Alessandra
- Tedeschi Alberto
- Tedeschi Sara
- Tedesco Andrea
- Tedesco Silvia
- Tenti Elena
- Teopompi Elisabetta
- Testa Filippo
- Teti Elisabetta
- Ticinesi Andrea
- Tieghi Tiziana
- Tinti Maria Giulia
- Titolo Giancarlo
- Tognella Silvia
- Tomasoni Gabriele
- Tomasoni Lina
- Tomasoni Lina Rachele
- Topino Simone
- Tornese Daniela
- Torre Federica
- Torretta Giacomo
- Torrini Monica
- Tosti Andrea
- Traballi Gabriella
- Trenti Chiara
- Trequattrini Tiziana
- Trezzi Michele
- Trojaniello Claudia
- Tropea Concetta Maria Gabriella
- Tundo Paolo
- Tura Paolo
- Turati Maria Luisa
- Turrini Mauro
- Uccella Ilaria
- Uccelli Maria Cristina
- Ucciferri Claudio
- Uggeri Cristiano
- Urru Silvana
- Ursillo Antonia
- Usai Carlo Andrea
- Vacca Elisabetta Blasi
- Vairo Giuseppe
- Valastro Federico
- Valenti Marco
- Valenti Vincenzo
- Valenzi Emiliano
- Valli Linda
- Vallone Alfredo
- Vanoni Nicolò
- Varbella Ferdinando
- Vassia Veronica
- Vecchiet Jacopo
- Vella Sabrina
- Venturi Bruna
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- Verhovez Andrea
- Veronese Lorenzo
- Versaci Alessandra
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- Vezzoli Monia
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- Vigliarolo Rossana
- Viglietti Rosaria
- Vincenti Antonella
- Vincenzi Marcello
- Vincenzo Brianti
- Vincenzo Valiani
- Viola Emanuela
- Viri Sabrina
- Virzì Giuseppe
- Visconti Giuseppe
- Visconti Stefano
- Visetti Enrico Maria
- Vitale Francesco
- Vitale Giovanni
- Vitale Maria Grazia
- Vitiello Leonarda
- Vitiello Silvio
- Viva Tommaso
- Viviani Rosangela
- Volkl Thomas
- Volpato Francesca
- Volta Carlo Alberto
- Vuotto Pietro
- Zammarchi Lorenzo
- Zanardini Cristina
- Zanatta Paolo
- Zanini Barbara
- Zanini Paola
- Zannetti Pio
- Zanolini Gabriele
- Zappa Maria Crisitna
- Zappulo Emanuela
- Zavarise Paola
- Zeme Angela Daniela
- Zenoni Davide
- Zini Enea
- Zoia Elena
- Zotti Maria Gioconda
- Zuccalà Francesco
- Zuccalà Paola
- Zuccarini Andrea
- Zummo Ugo
- Zunino Alessia
- Publication venue
- Publication date
- 01/01/2020
- Field of study
BackgroundTocilizumab blocks pro-inflammatory activity of interleukin-6 (IL-6), involved in pathogenesis of pneumonia the most frequent cause of death in COVID-19 patients.MethodsA multicenter, single-arm, hypothesis-driven trial was planned, according to a phase 2 design, to study the effect of tocilizumab on lethality rates at 14 and 30 days (co-primary endpoints, a priori expected rates being 20 and 35%, respectively). A further prospective cohort of patients, consecutively enrolled after the first cohort was accomplished, was used as a secondary validation dataset. The two cohorts were evaluated jointly in an exploratory multivariable logistic regression model to assess prognostic variables on survival.ResultsIn the primary intention-to-treat (ITT) phase 2 population, 180/301 (59.8%) subjects received tocilizumab, and 67 deaths were observed overall. Lethality rates were equal to 18.4% (97.5% CI: 13.6-24.0, P=0.52) and 22.4% (97.5% CI: 17.2-28.3, P<0.001) at 14 and 30 days, respectively. Lethality rates were lower in the validation dataset, that included 920 patients. No signal of specific drug toxicity was reported. In the exploratory multivariable logistic regression analysis, older age and lower PaO2/FiO2 ratio negatively affected survival, while the concurrent use of steroids was associated with greater survival. A statistically significant interaction was found between tocilizumab and respiratory support, suggesting that tocilizumab might be more effective in patients not requiring mechanical respiratory support at baseline.ConclusionsTocilizumab reduced lethality rate at 30 days compared with null hypothesis, without significant toxicity. Possibly, this effect could be limited to patients not requiring mechanical respiratory support at baseline.Registration EudraCT (2020-001110-38); clinicaltrials.gov (NCT04317092)
Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
- Author
- Adriana Agostinone
- Adriano Basile
- Adriano Gravina
- Adriano Gravina
- Adriano Peris
- Agata Belsito
- Agostino Tafuri
- Alarico Ariani
- Alberto Baratta
- Alberto Catania
- Alberto Guerra
- Alberto Maraolo
- Alberto Papi
- Alberto Ricchiardi
- Alberto Rossi
- Alberto Scala
- Alberto Tedeschi
- Aldo Roccaro
- Alessandra Brocchieri
- Alessandra Cattaneo
- Alessandra Ferrari
- Alessandra Manini
- Alessandra Maria Cemuschi
- Alessandra Mecozzi
- Alessandra Prozzo
- Alessandra Tebaldi
- Alessandra Versaci
- Alessandro Bordonali
- Alessandro Cerutti
- Alessandro Di Filippo
- Alessandro Ferrari
- Alessandro Mastroianni
- Alessandro Meli
- Alessandro Morettini
- Alessandro Olivetti
- Alessandro Scartabellati
- Alessia Pisterna
- Alessia Zunino
- Alessio Lipari
- Alessio Maroccia
- Alessio Pampaloni
- Alessio Peregrinelli
- Alex Hofer
- Alfonso Masullo
- Alfonso Savio
- Alfredo Marinelli
- Alfredo Molteni
- Alfredo Molteni
- Alfredo Vallone
- Alice Moroni
- Alice Repossi
- Amalia Buglione
- Ambrogio Curtolo
- Amelia Filippelli
- Anacleto Romano
- Anaflorina Matei
- Andrea Angheben
- Andrea Ansuini
- Andrea Antonini
- Andrea Ballarin
- Andrea Ballotta
- Andrea Bellone
- Andrea Bianchin
- Andrea Biondi
- Andrea Boschi
- Andrea Calcagno
- Andrea Caruso
- Andrea Castellan
- Andrea Dalbeni
- Andrea De Monte
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- Andrea Doria
- Andrea Fadda
- Andrea Frascati
- Andrea Gallo
- Andrea Giachi
- Andrea Magnaca
- Andrea Manzi
- Andrea Marco Machiavelli
- Andrea Marino
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- Annalisa Brianti
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- Annamaria Corsaro
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- Annamaria Ruggieri
- Annunziata De Rosa
- Anselmo Riccio
- Antoenlla Grisolia
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- TOCIVID-19 investigators
- Tommaso Viva
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- Ugo Zummo
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- Valentina Barbato
- Valentina Benedetti
- Valentina Isgrò
- Valentina Marchetti
- Valentina Raffaelli
- Valentina Rastellino
- Valeria Belvisi
- Valeria Di Biase
- Valeria Nava
- Valerio Del Bono
- Vanessa Dell'uomo
- Vanni Agnoletti
- Venerino Poletti
- Veronica Del Punta
- Veronica Lonati
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- Veronica Vassia
- Vincenzo Bianco
- Vincenzo Cardinale
- Vincenzo Cuzzone
- Vincenzo Esposito
- Vincenzo Galati
- Vincenzo Gentili
- Vincenzo Messina
- Vincenzo Mondino
- Vincenzo Montesarchio
- Vincenzo Montesarchio
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- Vincenzo Valenti
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- Vito Sante Mercurio
- Vittoria Favero
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- Viviana Ravagnani
- Walter Ageno
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- Ylenia Berté
- Zaira Di Rosa
- Zeno Pasquini
- Zocchetti Cristina
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- Author
- Abdelmohsen Kotb
- Abe Akihisa
- Abedin Md Joynal
- Abeliovich Hagai
- Adachi Hiroaki
- Adams Christopher M.
- Adams Peter D.
- Adeli Khosrow
- Adhihetty Peter J.
- Adler Sharon G.
- Agam Galila
- Agarwal Rajesh
- Aghi Manish K.
- Agnello Maria
- Agostinis Patrizia
- Aguilar Patricia V.
- Aguirre-Ghiso Julio
- Airoldi Edoardo M.
- Ait-Si-Ali Slimane
- Akematsu Takahiko
- Akporiaye Emmanuel T.
- Al-Rubeai Mohamed
- Albaiceta Guillermo M.
- Albanese Chris
- Albani Diego
- Albert Matthew L.
- Aldudo Jesus
- Alguel Hana
- Alirezaei Mehrdad
- Alloza Iraide
- Almasan Alexandru
- Almonte-Beceril Maylin
- Alnemri Emad S.
- Alonso Covadonga
- Altan-Bonnet Nihal
- Altieri Dario C.
- Alvarez Silvia
- Alvarez-Erviti Lydia
- Alves Sandro
- Amadoro Giuseppina
- Amano Atsuo
- Amantini Consuelo
- Ambrosio Santiago
- Amelio Ivano
- Amer Amal O.
- Amessou Mohamed
- Amon Angelika
- An Zhenyi
- Ana Gonzalez-Polo Rosa
- Anania Frank A.
- Andersen Stig U.
- Andley Usha P.
- Andreadi Catherine K.
- Andrieu-Abadie Nathalie
- Anel Alberto
- Ann David K.
- Anoopkumar-Dukie Shailendra
- Antonioli Manuela
- Aoki Hiroshi
- Apostolova Nadezda
- Aquila Saveria
- Aquilano Katia
- Araki Koichi
- Arama Eli
- Aranda Agustin
- Araya Jun
- Arcaro Alexandre
- Arias Esperanza
- Arimoto Hirokazu
- Ariosa Aileen R.
- Armstrong Jane L.
- Arnould Thierry
- Arozena Abraham Acevedo
- Arsov Ivica
- Asanuma Katsuhiko
- Askanas Valerie
- Asselin Eric
- Atarashi Ryuichiro
- Atherton Sally S.
- Atkin Julie D.
- Attardi Laura D.
- Auberger Patrick
- Auburger Georg
- Aurelian Laure
- Autelli Riccardo
- Avagliano Laura
- Avantaggiati Maria Laura
- Avrahami Limor
- Awale Suresh
- Azad Neelam
- Bachetti Tiziana
- Backer Jonathan M.
- Bae Dong-Hun
- Bae Jae-Sung
- Bae Ok-Nam
- Bae Soo Han
- Baehrecke Eric H.
- Baek Seung-Hoon
- Baghdiguian Stephen
- Bagniewska-Zadworna Agnieszka
- Bai Hua
- Bai Jie
- Bai Xue-Yuan
- Bailly Yannick
- Balaji Kithiganahalli Narayanaswamy
- Balduini Walter
- Ballabio Andrea
- Balzan Rena
- Banerjee Rajkumar
- Banhegyi Gabor
- Bao Haijun
- Barbato Daniele Lettieri
- Barbeau Benoit
- Barrachina Maria D.
- Barreiro Esther
- Bartel Bonnie
- Bartolome Alberto
- Bassham Diane C.
- Bassi Maria Teresa
- Bast Robert C., Jr.
- Basu Alakananda
- Batista Maria Teresa
- Batoko Henri
- Battino Maurizio
- Bauckman Kyle
- Baumgarner Bradley L.
- Bayer K. Ulrich
- Beale Rupert
- Beaulieu Jean-Francois
- Beck George R., Jr.
- Becker Christoph
- Beckham J. David
- Bedard Pierre-Andre
- Bednarski Patrick J.
- Begley Thomas J.
- Behl Christian
- Behrends Christian
- Behrens Georg M. N.
- Behrns Kevin E.
- Bejarano Eloy
- Belaid Amine
- Belleudi Francesca
- Benard Giovanni
- Berchem Guy
- Bergamaschi Daniele
- Bergami Matteo
- Berkhout Ben
- Berliocchi Laura
- Bernard Amelie
- Bernard Monique
- Bernassola Francesca
- Bertolotti Anne
- Bess Amanda S.
- Besteiro Sebastien
- Bettuzzi Saverio
- Bhalla Savita
- Bhattacharyya Shalmoli
- Bhutia Sujit K.
- Biagosch Caroline
- Bianchi Michele Wolfe
- Biard-Piechaczyk Martine
- Billes Viktor
- Bincoletto Claudia
- Bingol Baris
- Bird Sara W.
- Bitoun Marc
- Bjedov Ivana
- Blackstone Craig
- Blanc Lionel
- Blanco Guillermo A.
- Blomhoff Heidi Kiil
- Boada-Romero Emilio
- Boeckler Stefan
- Boes Marianne
- Boesze-Battaglia Kathleen
- Boise Lawrence H.
- Bolino Alessandra
- Boman Andrea
- Bonaldo Paolo
- Bordi Matteo
- Bosch Jurgen
- Botana Luis M.
- Botti Joelle
- Bou German
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- Bouchecareilh Marion
- Boucher Marie-Josee
- Boulton Michael E.
- Bouret Sebastien G.
- Boya Patricia
- Boyer-Guittaut Michaeel
- Bozhkov Peter V.
- Brady Nathan
- Braga Vania M. M.
- Brancolini Claudio
- Braus Gerhard H.
- Bravo-San Pedro Jose M.
- Brennan Lisa A.
- Bresnick Emery H.
- Bressan Queiroz de Figueiredo Regina Celia
- Brest Patrick
- Bridges Dave
- Bringer Marie-Agnes
- Brini Marisa
- Brito Glauber C.
- Brodin Bertha
- Brookes Paul S.
- Brown Eric J.
- Brown Karen
- Broxmeyer Hal E.
- Bruhat Alain
- Brum Patricia Chakur
- Brumell John H.
- Brunetti-Pierri Nicola
- Bryson-Richardson Robert J.
- Buch Shilpa
- Buchan Alastair M.
- Budak Hikmet
- Buetikofer Peter
- Bulavin Dmitry V.
- Bultman Scott J.
- Bultynck Geert
- Bumbasirevic Vladimir
- Burelle Yan
- Burke Robert E.
- Burmeister Margit
- Caberlotto Laura
- Cadwell Ken
- Cahova Monika
- Cai Dongsheng
- Cai Jingjing
- Cai Qian
- Calatayud Sara
- Camougrand Nadine
- Campanella Michelangelo
- Campbell Grant R.
- Campbell Matthew
- Campello Silvia
- Candau Robin
- Caniggia Isabella
- Cantoni Lavinia
- Cao Lizhi
- Caplan Allan B.
- Caraglia Michele
- Cardinali Claudio
- Cardoso Sandra Morais
- Carew Jennifer S.
- Carleton Laura A.
- Carlin Cathleen R.
- Carloni Silvia
- Carlsson Sven R.
- Carmona-Gutierrez Didac
- Carneiro Leticia A. M.
- Carnevali Oliana
- Carra Serena
- Carrier Alice
- Carroll Bernadette
- Casas Caty
- Casas Josefina
- Cassinelli Giuliana
- Castets Perrine
- Castro-Obregon Susana
- Cavallini Gabriella
- Ceccherini Isabella
- Cecconi Francesco
- Cederbaum Arthur I.
- Cena Valentin
- Cenci Simone
- Cerella Claudia
- Cervia Davide
- Cetrullo Silvia
- Chaachouay Hassan
- Chae Han-Jung
- Chagin Andrei S.
- Chai Chee-Yin
- Chakrabarti Gopal
- Chamilos Georgios
- Chan Edmond Y. W.
- Chan Matthew T. V.
- Chandra Dhyan
- Chandra Pallavi
- Chang Chih-Peng
- Chang Raymond Chuen-Chung
- Chang Ta Yuan
- Chatham John C.
- Chatterjee Saurabh
- Chauhan Santosh
- Che Yongsheng
- Cheetham Michael E.
- Cheluvappa Rajkumar
- Chen Chun-Jung
- Chen Gang
- Chen Guang-Chao
- Chen Guoqiang
- Chen Hongzhuan
- Chen Jeff W.
- Chen Jian-Kang
- Chen Min
- Chen Mingzhou
- Chen Peiwen
- Chen Qi
- Chen Quan
- Chen Shang-Der
- Chen Si
- Chen Steve S-L
- Chen Wei
- Chen Wei-Jung
- Chen Wen Qiang
- Chen Wenli
- Chen Xiangmei
- Chen Yau-Hung
- Chen Ye-Guang
- Chen Yin
- Chen Yingyu
- Chen Yongshun
- Chen Yu-Jen
- Chen Yue-Qin
- Chen Yujie
- Chen Zhen
- Chen Zhong
- Cheng Alan
- Cheng Christopher H. K.
- Cheng Hua
- Cheong Heesun
- Cherry Sara
- Chesney Jason
- Cheung Chun Hei Antonio
- Chevet Eric
- Chi Hsiang Cheng
- Chi Sung-Gil
- Chiacchiera Fulvio
- Chiang Hui-Ling
- Chiarelli Roberto
- Chiariello Mario
- Chieppa Marcello
- Chin Lih-Shen
- Chiong Mario
- Chiu Gigi N. C.
- Cho Dong-Hyung
- Cho Ssang-Goo
- Cho William C.
- Cho Yong-Yeon
- Cho Young-Seok
- Choi Augustine M. K.
- Choi Eui-Ju
- Choi Eun-Kyoung
- Choi Jayoung
- Choi Mary E.
- Choi Seung-Il
- Chou Tsui-Fen
- Chouaib Salem
- Choubey Divaker
- Choubey Vinay
- Chow Kuan-Chih
- Chowdhury Kamal
- Chu Charleen T.
- Chuang Tsung-Hsien
- Chun Taehoon
- Chung Hyewon
- Chung Taijoon
- Chung Yuen-Li
- Chwae Yong-Joon
- Cianfanelli Valentina
- Ciarcia Roberto
- Ciechomska Iwona A.
- Ciriolo Maria Rosa
- Cirone Mara
- Claerhout Sofie
- Clague Michael J.
- Claria Joan
- Clarke Peter G. H.
- Clarke Robert
- Clementi Emilio
- Cleyrat Cedric
- Cnop Miriam
- Coccia Eliana M.
- Cocco Tiziana
- Codogno Patrice
- Coers Joern
- Cohen Ezra E. W.
- Colecchia David
- Coletto Luisa
- Coll Nuria S.
- Colucci-Guyon Emma
- Comincini Sergio
- Condello Maria
- Cook Katherine L.
- Coombs Graham H.
- Cooper Cynthia D.
- Cooper J. Mark
- Coppens Isabelle
- Corasaniti Maria Tiziana
- Corazzari Marco
- Corbalan Ramon
- Corcelle-Termeau Elisabeth
- Cordero Mario D.
- Corral-Ramos Cristina
- Corti Olga
- Cossarizza Andrea
- Costelli Paola
- Costes Safia
- Costes Safia
- Coto-Montes Ana
- Cottet Sandra
- Couve Eduardo
- Covey Lori R.
- Cowart L. Ashley
- Cox Jeffery S.
- Coxon Fraser P.
- Coyne Carolyn B.
- Cragg Mark S.
- Craven Rolf J.
- Crepaldi Tiziana
- Crespo Jose L.
- Criollo Alfredo
- Crippa Valeria
- Cruz Maria Teresa
- Cuervo Ana Maria
- Cuezva Jose M.
- Cui Taixing
- Cutillas Pedro R.
- Czaja Mark J.
- Czyzyk-Krzeska Maria F.
- D'Amelio Marcello
- D'Orazi Gabriella
- Dagda Ruben K.
- Dahmen Uta
- Dai Chunsun
- Dai Wenjie
- Dai Yun
- Dalby Kevin N.
- Dalmasso Guillaume
- Damme Markus
- Darfeuille-Michaud Arlette
- Dargemont Catherine
- Darley-Usmar Victor M.
- Dasarathy Srinivasan
- Dasgupta Biplab
- Dash Srikanta
- Dass Crispin R.
- Davey Hazel Marie
- Davids Lester M.
- Davila David
- Davis Roger J.
- Dawson Ted M.
- Dawson Valina L.
- Daza Paula
- de Belleroche Jackie
- de Figueiredo Paul
- de la Fuente Jose
- De Martino Luisa
- De Matteis Antonella
- De Meyer Guido
- De Milito Angelo
- De Santi Mauro
- de Souza Wanderley
- De Tata Vincenzo
- De Zio Daniela
- Debnath Jayanta
- Dechant Reinhard
- Decuypere Jean-Paul
- Deegan Shane
- Dehay Benjamin
- Del Bello Barbara
- Del Re Dominic P.
- Delage-Mourroux Regis
- Delbridge Lea M. D.
- Deldicque Louise
- Delorme-Axford Elizabeth
- Deng Yizhen
- Dengjel Joern
- Denizot Melanie
- Dent Paul
- Der Channing J.
- Deretic Vojo
- Derrien Benoit
- Deutsch Eric
- Devarenne Timothy P.
- Devenish Rodney J.
- Di Bartolomeo Sabrina
- Di Daniele Nicola
- Di Domenico Fabio
- Di Nardo Alessia
- Di Paola Simone
- Di Pietro Antonio
- Di Renzo Livia
- DiAntonio Aaron
- Diaz-Araya Guillermo
- Diaz-Laviada Ines
- Diaz-Meco Maria T.
- Diaz-Nido Javier
- Dickey Chad A.
- Dickson Robert C.
- Diederich Marc
- Digard Paul
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- Ding Chan
- Ding Wen-Xing
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- Diwan Abhinav
- Djavaheri-Mergny Mojgan
- Dmytruk Kostyantyn
- Dobson Renwick C. J.
- Doetsch Volker
- Dokladny Karol
- Dokudovskaya Svetlana
- Donadelli Massimo
- Dong X. Charlie
- Dong Xiaonan
- Dong Zheng
- Donohue Terrence M., Jr.
- Doran Kelly S.
- Dorn Gerald W., II
- dos Santos Claudia Nunes
- Dosenko Victor
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- Dumit Veronica I.
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- Eichinger Ludwig
- Eisenberg Tobias
- Eisenberg-Lerner Avital
- Eissa N. Tony
- El-Deiry Wafik S.
- El-Khoury Victoria
- Elazar Zvulun
- Eldar-Finkelman Hagit
- Elliott Chris J. H.
- Emanuele Enzo
- Emmenegger Urban
- Engedal Nikolai
- Engelbrecht Anna-Mart
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- Yoo Yeong-Min
- Yoo Young Hyun
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- Yoshida Ken-Ichi
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- Yu Jin-Tai
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- Yu W. Haung
- Yu Xiao-Fang
- Yu Zhengping
- Yuan Junying
- Yuan Zhi-Min
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- Yue Jianbo
- Yue Zhenyu
- Zacks David N.
- Zacksenhaus Eldad
- Zaffaroni Nadia
- Zaglia Tania
- Zakeri Zahra
- Zecchini Vincent
- Zeng Jinsheng
- Zeng Min
- Zeng Qi
- Zervos Antonis S.
- Zhang Donna D.
- Zhang Fan
- Zhang Guo
- Zhang Guo-Chang
- Zhang Hao
- Zhang Hong
- Zhang Hong
- Zhang Hongbing
- Zhang Jian
- Zhang Jian
- Zhang Jiangwei
- Zhang Jianhua
- Zhang Jing-pu
- Zhang Li
- Zhang Lin
- Zhang Lin
- Zhang Long
- Zhang Ming-Yong
- Zhang Xiangnan
- Zhang Xu Dong
- Zhang Yan
- Zhang Yang
- Zhang Yanjin
- Zhang Yingmei
- Zhang Yunjiao
- Zhao Mei
- Zhao Wei-Li
- Zhao Xiaonan
- Zhao Yan G.
- Zhao Ying
- Zhao Yongchao
- Zhao Yu-Xia
- Zhao Zhendong
- Zhao Zhizhuang J.
- Zheng Dexian
- Zheng Xi-Long
- Zheng Xiaoxiang
- Zhivotovsky Boris
- Zhong Qing
- Zhou Guang-Zhou
- Zhou Guofei
- Zhou Huiping
- Zhou Shu-Feng
- Zhou Xu-Jie
- Zhu Hongxin
- Zhu Hua
- Zhu Wei-Guo
- Zhu Wenhua
- Zhu Xiao-Feng
- Zhu Yuhua
- Zhuang Shi-Mei
- Zhuang Xiaohong
- Ziparo Elio
- Zois Christos E.
- Zoladek Teresa
- Zong Wei-Xing
- Zorzano Antonio
- Zughaier Susu M.
- Publication venue
- Publication date
- 01/01/2016
- Field of study
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akçay Özlem
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
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- Chowdhury Sharfuddin M
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- de Andrés-Asenjo Beatriz
- de Deken Julie
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- en Siew Bei
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- Gomes Carina
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- Van Charles Berlo
- Van Maarten Heinsbergen
- Vardanyan Armen
- Varela-Rodríguez Lorena
- Varghese Chris
- Varoli Michele
- Vasale Alessandro
- Vasiukova Evgeniia-Surgeon
- Vassiliu Pantelis
- Vaughan-Shaw Peter G
- Vázquez-Fernández Andrea
- Väyrynen Antti
- Vecchio Pablo
- Vederaki Styliani-Aikaterini
- Veetil Sreejith Kannummal
- Velchuru Vamsi
- Velez Cristina
- Vendrell Laura Lopez
- Venezia Dario Francesco
- Venn Mary
- Venn Mary L
- Venskutonis Donatas
- Ventorutti Tatiana
- Vera Marina Teresa Ramirez
- Vera-Mansilla Cristina
- Veracierto Federico
- Vergara-Fernández Omar
- Verma Devanshi
- Verre Luigi
- Vespo Damiano
- Vicente-Villena Juan Pablo
- Victor Catherine
- Vieira Pedro
- Vieyra Nicolas
- Vignali Andrea
- Vigneswaran Natalia
- Vigorita Vincenzo
- Vihervaara Hanna
- Vijayagopal Kesav Aditya
- Vijayan Varun
- Vilain Luciano Ferreira
- Villa Gianluca
- Villalobos Santiago
- Villarino-Villa Laura
- Vino Smila
- Viola Marcelo
- Viscosi Francesca
- Vishnoi Jeewan Ram
- Vlad Catalin
- Volkoviene Gerda
- Volturo Lino
- Vural Ummuhan
- Wagdy Michael
- Waha James
- Waheed Mariam
- Waindeskar Vaishali
- Wakkaf Habib
- Walędziak Maciej
- Walsh Adam
- Wang Jaw Yuan
- Wani Rauf
- Wanshantha Dinamulla
- Waqar Usama
- Ward Nicholas
- Watanabe Jun
- Wątroba Anna
- Wells Johanna
- Westzaan Natalia
- Wickramarathne Rasika
- Wickramasinghe Dakshitha
- Widatalla Abu Bakr H
- Widyaningsih Rizky
- Wijenayake Wasantha
- Wilson Jeremy
- Wilson Kasmira
- Windels An
- Witjes Caroline
- Wong Siew Ching
- Woodward Andrew
- Wright Deborah
- Wright Jonathan
- Wu Scott
- Xanthis Athanasios
- Xavier Ruben
- Xenaki Sofia
- Xynos Evangelos
- Yadav Ram Kishan
- Yadev I P
- Yague Julio
- Yakout Nadia
- Yakunina Natalia
- Yalkin Ömer
- Yanishev Alexey
- Yao Hongwei
- Yazici Pinar
- Yemez Kursat
- Yew Chor Kuan
- Yiğit Direnç
- Yılmaz Gülseren
- Yilmazlar Tuncay
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)