An Observational Cohort Study on Delayed-Onset Infections after Mandibular Third-Molar Extractions.

OBJECTIVES: The purpose of the present study was to investigate the occurrence and clinical features of delayed-onset infections after mandibular third-molar extractions. METHOD AND MATERIALS: An observational cohort study was conducted on 179 patients undergoing mandibular third-molar extraction between January 2013 and December 2015, for a total of 217 extractions. Data were recorded at the time of extraction (T0), on suture removal seven days later (T1), and 30 days after the extraction, when patients were contacted and asked about their healing process (T2). The statistical analysis was performed with nonparametric tests. A p value lower than 0.05 was considered statistically significant. RESULTS: Eight delayed-onset infections were recorded, amounting to 3.7% of all extractions. The median time elapsing from the extraction to the delayed-onset infection was 35 days (IQR 28-40; min 24-max 49). Younger age and longer surgical procedures seemed to be more often associated with this complication. CONCLUSION: Delayed-onset infections after third-molar extractions are relatively rare postoperative complications characterized by a swelling, usually with a purulent discharge. Patients should be informed of this possibility, which might develop even several weeks after the extraction

Gas gain on single wire chambers filled with pure isobutane at low pressure

The gas gain of single-wire chambers filled with isobutane, with cell cross-section 12x12 mm and wire diameters of 15, 25, 50 and 100 $\mu$m, has been measured at pressures ranging 12-92 Torr. Contrary to the experience at atmospheric pressure, at very low pressures the gas gain on thick wires is higher than that on thin wires at the same applied high voltage as was recently shown. Bigger wire diameters should be used in wire chambers operating at very low pressure if multiple scattering on wires is not an issue.Comment: 9 pages, 6 figure

Drift velocity and gain in argon- and xenon-based mixtures

We present measurements of drift velocities and gains in gas mixtures based on Ar and Xe, with CO2, CH4, and N2 as quenchers, and compare them with calculations. In particular, we show the dependence of Ar- and Xe-CO2 drift velocities and gains on the amount of nitrogen contamination in the gas, which in real experiments may build up through leaks. A quantification of the Penning mechanism which contributes to the Townsend coefficients of a given gas mixture is proposed.Comment: 11 pages, 7 figures, accepted for publication in Nucl.Instrum.Meth. A. Data files available at http://www-alice.gsi.de/tr

High Rate Performance of Drift Tubes

This article describes calculations and measurements of space charge effects due to high rate irradiation in high resolution drift tubes. Two main items are studied: the reduction of the gas gain and changes of the drift time. Whereas the gain reduction is similar for all gases and unavoidable, the drift time changes depend on the kind of gas that is used. The loss in resolution due to high particle rate can be minimized with a suitable gas. This behaviour is calculable, allowing predictions for new gas mixtures.Comment: 20 pages, submitted to Nuclear Instruments and Methods

Conservative non-surgical management of horizontal root-fractured maxillary incisors in a young male with angle class ii, division 2, malocclusion

Horizontal root fractures are a rare emergency in a dental office. The injury involves periodontal ligament, cementum, dentine and pulp. The healing is influenced by the location of the root fracture, the displacement of the fragments and the status of the pulp. This report presents a clinical case of horizontal fractures to both maxillary central incisors due to an act of violence. The type of occlusion has avoided a severe diastasis of the coronal parts with a subsequent damage to the pulp and periodontum. The fractures were treated with an orthodontic splint without any further therapy and hard tissue healing was observed. A careful diagnosis and well-timed treatment planning usually allow a cost-efficient and biologically-oriented therapy with a favorable outcome

A NEW MULTI-RESOLUTION ALGORITHM TO STORE AND TRANSMIT COMPRESSED DTM

WebGIS and virtual globes allow DTMs distribution and three dimensional representations to the Web users' community. In these applications, the database storage size represents a critical point. DTMs are obtained by some sampling or interpolation on the raw observations and typically are stored and distributed by data based models, like for example regular grids. A new approach to store and transmit DTMs is presented. The idea is to use multi-resolution bilinear spline functions to interpolate the observations and to model the terrain. More in detail, the algorithm performs the following actions. 1) The spatial distribution of the observations is investigated. Where few data are available, few levels of splines are activated while more levels are activated where the raw observations are denser: each new level corresponds to an halving of the spline support with respect to the previous level. 2) After the selection of the spline functions to be activated, the relevant coefficients are estimated by interpolating the observations. The interpolation is computed by batch least squares. 3) Finally, the estimated coefficients of the splines are stored. The model guarantees a local resolution consistent with the data density and can be defined analytical, because the coefficients of a given function are stored instead of a set of heights. The approach is discussed and compared with the traditional techniques to interpolate, store and transmit DTMs, considering accuracy and storage requirements. It is also compared with another multi-resolution technique. The research has been funded by the INTERREG HELI-DEM (Helvetia Italy Digital Elevation Model) project

A Dtm Multi-Resolution Compressed Model for Efficient Data Storage and Network Transfer

In recent years the technological evolution of terrestrial, aerial and satellite surveying, has considerably increased the measurement accuracy and, consequently, the quality of the derived information. At the same time, the smaller and smaller limitations on data storage devices, in terms of capacity and cost, has allowed the storage and the elaboration of a bigger number of instrumental observations. A significant example is the terrain height surveyed by LIDAR (LIght Detection And Ranging) technology where several height measurements for each square meter of land can be obtained. The availability of such a large quantity of observations is an essential requisite for an in-depth knowledge of the phenomena under study. But, at the same time, the most common Geographical Information Systems (GISs) show latency in visualizing and analyzing these kind of data. This problem becomes more evident in case of Internet GIS. These systems are based on the very frequent flow of geographical information over the internet and, for this reason, the band-width of the network and the size of the data to be transmitted are two fundamental factors to be considered in order to guarantee the actual usability of these technologies. In this paper we focus our attention on digital terrain models (DTM's) and we briefly analyse the problems about the definition of the minimal necessary information to store and transmit DTM's over network, with a fixed tolerance, starting from a huge number of observations. Then we propose an innovative compression approach for sparse observations by means of multi-resolution spline functions approximation. The method is able to provide metrical accuracy at least comparable to that provided by the most common deterministic interpolation algorithms (inverse distance weighting, local polynomial, radial basis functions). At the same time it dramatically reduces the number of information required for storing or for transmitting and rebuilding a digital terrain model dataset. A brief description of the method is presented and comparisons about the accuracy and data-store compression obtained with respect to other interpolators are shown

Tidal errors and deformations in regional GPS networks

At present, the tidal correction model described in the IERS 2003 Conventions should be applied in the processing of permanent networks: in brief, the model involves the computation of a first order tidal correction plus some corrective terms, as functions of space and time. In the BERNESE software, one of the main scientific softwares for GPS network processing, the IERS tidal model is implemented; in July 2004, a bug in the tidal correction routine was identified by one of the paper authors and corrected by the BERNESE staff: the error concerned a second order term, related to the semidiurnal tidal signal. An experimental analysis on the error effects in the results stemming from processing of regional networks has been carried out. A network of 8 European permanent GPS stations has been selected: the network choice ensures heterogeneity in the length and the orientation of the baselines. One year of data has been considered and two elaborations of the data have been performed using the BERNESE 4.2 SW, by applying the same processing strategy and, respectively, the wrong (old) and the right (corrected) tidal correction routine. The differences in the network results and the deformations caused by the error are discussed

lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis

Effector-memory T cells expressing Fas (Apo-1/CD95) are switched to an apoptotic program by cross-linking with Fas-ligand (FasL). Consequently, tumors that express FasL can induce apoptosis of infiltrating Fas-positive T lymphocytes and subdue any antitumor host immune response. Since Epstein-Barr virus (EBV)-associated tumors such as Hodgkin lymphoma (HL) and nasopharyngeal carcinoma (NPC) express FasL, we determined whether EBV-specific cytotoxic T lymphocytes (EBV-CTLs) could be modified to resist this evasion strategy. We show that long-term down-modulation of Fas can be achieved in EBV-CTLs by transduction with small interfering RNA (siRNA) encoded in a retrovirus. Modified T cells resisted Fas/FasL-mediated apoptosis compared with control cells and showed minimal cleavage of the caspase3 substrate poly(ADP-ribose) polymerase (PARP) protein after Fas engagement. Prolonged Fas stimulation selected a uniformly Fas(low) and FasL resistant population. Removal of responsiveness to this single death signal had no other discernible effects on EBV-CTLs. In particular, it did not lead to their autonomous growth since the modified EBV-CTLs remained polyclonal, and their survival and proliferation retained dependence on antigen-specific stimulation and on the presence of other physiologic growth signals. EBV-CTLs with knocked down Fas should have a selective functional and survival advantage over unmodified EBV-CTLs in the presence of tumors expressing FasL and may be of value for adoptive cellular therapy. (c) 2005 by The American Society of Hematology