103 research outputs found

    Erratum: Corrigendum: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

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    International Chicken Genome Sequencing Consortium. The Original Article was published on 09 December 2004. Nature432, 695–716 (2004). In Table 5 of this Article, the last four values listed in the ‘Copy number’ column were incorrect. These should be: LTR elements, 30,000; DNA transposons, 20,000; simple repeats, 140,000; and satellites, 4,000. These errors do not affect any of the conclusions in our paper. Additional information. The online version of the original article can be found at 10.1038/nature0315

    Crystal structure of an unknown solvate of dodecakis(ÎŒ2-alaninato-1:2Îș2O:N,O)cerium(III)hexanickel(II) aquatris(hydroxido-ÎșO)tris(nitrato-Îș2O,Oâ€Č)cerate(III)

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    The chiral title compound, [CeNi6(C3H6NO2)12][Ce(NO3)3(OH)3(H2O)], comprises a complex heterometallic Ni/Ce cation and a homonuclear Ce anion. Both the cation and anion exhibit point group symmetry 3. with the CeIII atom situated on the threefold rotation axis. The cation metal core consists of six NiII atoms coordinated in a slightly distorted octahedral N2O4 configuration by N and O atoms of 12 deprotonated l-alaninate ligands exhibiting both bridging and chelating modes. This metal–organic coordination motif encapsulates one CeIII atom that shows an icosahedral coordination by the O-donor atoms of the l-alaninate ligands, with Ce—O distances varying in the range 2.455 (5)–2.675 (3) Å. In the anion, the central CeIII ion is bound to three bidentate nitrate ligands, to three hydroxide ligands and to one water molecule, with Ce—O distances in the range 2.6808 (19)–2.741 (2) Å. The H atoms of the coordinating water molecule are disordered over three positions due to its location on a threefold rotation axis. Disorder is also observed in fragments of two l-alaninate ligands, with occupancy ratios of 0.608 (14):0.392 (14) and 0.669 (8):0.331 (8), respectively, for the two sets of sites. In the crystal, the complex cations and anions assemble through O—H...O and N—H...O hydrogen bonds into a three-dimensional network with large voids of approximately 1020 Å3. The contributions of highly disordered ethanol and water solvent molecules to the diffraction data were removed with the SQUEEZE procedure [Spek (2015). Acta Cryst. C71, 9–18]. The given chemical formula and other crystal data do not take into account the unknown amount of these solvent molecules

    (2-Benzoyl-1-phenylethenolato-Îș2O,Oâ€Č)bis[2-(1-phenyl-1H-benzimidazol-2-yl)phenyl-ÎșC1]iridium(III) dichloromethane disolvate

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    We present here synthesis and crystal structure of a neutral IrIII complex, [Ir(C19H13N2)2(C15H11O2)]·2CH2Cl2 or [Ir(C^N)2O^O]·2CH2Cl2, where C^N is 1,2-diphenyl-1H-benzimidazole and O^O is 2-benzoyl-1-phenylethenolate. The coordination sphere of the IrIII atom, located on a twofold rotation axis, is that of a slighlty distorted C2N2O2 octahedron, with the N atoms in a trans configuration. In the crystal, complex molecules assemble through weak C—H...π interactions in the range 2.699 (3)–2.892 (3) Å. The solvent CH2Cl2 molecules reside in channels aligned along the a axis and are connected to the complex molecules by C—H...O interactions

    Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.

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    A large number of cDNA inserts were sequenced from a high-quality library of chicken bursal lymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collection represents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line

    Full-Length cDNAs from Chicken Bursal Lymphocytes to Facilitate Gene Function Analysis

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    A large number of cDNA inserts were sequenced from a high-quality library of chicken bursallymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collectionrepresents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line

    l‑Alanine/Nickel-Induced Size Sorting of Lanthanide(III) Ions in 4f–4fâ€Č Heterometallic Complexes

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    A versatile approach to create a novel class of mixed-lanthanide compounds with predetermined locations of different lanthanides in cationic and anionic positions has been developed. Pure 4f–4fâ€Č heterometallic complexes were constructed from two independent building blocks: the complex cation [Ln­{Ni­(ala)<sub>2</sub>}<sub>6</sub>]<sup>3+</sup> (ala = l-alaninate), which can be formed by La<sup>3+</sup>, Ce<sup>3+</sup>, Pr<sup>3+</sup>, and Nd<sup>3+</sup> exclusively, and the anion [Gd­(NO<sub>3</sub>)<sub>3</sub>(OH)<sub>3</sub>(H<sub>2</sub>O)]<sup>3–</sup>. The compositions and structures of the complexes were studied by X-ray crystallography, energy-dispersive X-ray spectroscopy, and inductively coupled plasma mass spectrometry. The X-ray structural analysis showed the high rigidity of the l-alanine/Ni­(II) supramolecular unit in the complex cations, which affected immediately its selectivity toward certain lanthanides

    Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

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    We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to have its genome sequenced, the draft sequence of its genome--composed of approximately one billion base pairs of sequence and an estimated 20,000-23,000 genes--provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes. For example, the evolutionary distance between chicken and human provides high specificity in detecting functional elements, both non-coding and coding. Notably, many conserved non-coding sequences are far from genes and cannot be assigned to defined functional classes. In coding regions the evolutionary dynamics of protein domains and orthologous groups illustrate processes that distinguish the lineages leading to birds and mammals. The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture
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