High-Temperature, Low-Cycle Fatigue Behavior of Tantalum

High temperature, low cycle fatigue tests of tantalum in inert argon atmospher

Dynamics of a fully stochastic discretized neuronal model with excitatory and inhibitory neurons

We consider here an extension and generalization of the stochastic neuronal network model developed by DeVille et al.; their model corresponded to an all-to-all network of discretized integrate-and-fire excitatory neurons where synapses are failure-prone. It was shown that this model exhibits different metastable phases of asynchronous and synchronous behavior, since the model limits on a mean-field deterministic system with multiple attractors. Our work investigates adding inhibition into the model. The new model exhibits the same metastable phases, but also exhibits new non-monotonic behavior that was not seen in the DeVille et al. model. The techniques used by DeVille et al. for finding the mean-field limit are not suitable for this new model. We explore early attempts at obtaining a new mean-field deterministic system that would give us an understanding of the behavior seen in the new model. After redefining the process we do find a mean-field deterministic system that the model limits on, and we investigate the behavior of the new model studying the mean-field system

Variability of Annual Iowa Precipitation During the Past 95 Years

With increased consumption of fossil fuels has come warnings that the global atmosphere could be overtaxed with carbon dioxide and other combustion byproducts. The most popular scenario suggests a warming of the subpolar area with an extension of the grain belt. This warming could place the present grain belt in a warmer and drier climate. Each time a portion of the grain belt experiences a temperature or precipitation anomaly, the suggestion of a climatic change is raised. The present paper addresses the question of medium-term, 95-year change in Iowa annual precipitation as well as linkage between precipitation and temperature anomalies. Similar studies in Europe and the United Kingdom, where unbroken precipitation records extend back almost 300 years, show periods up to 50 or 75 years where a jump in the annual mean has occurred. The fact that such anomalies extend back before the industrial revolution suggests other factors may cause such changes. With only about 100 years of climatological records here in the grain belt, it may not be possible to identify long-term, natural oscillations or a true, long-term trend. Records at four sites, Cedar Rapids, Des Moines, Dubuque, and Storm Lake, were analyzed in search of true jumps or trends in the climatic record. There was no question that the record had dry and wet periods, some extending over a period of ten or fifteen years. The conclusions were that, although extended periods seemed to be above or below the long-term mean, these anomalies had tenuous linkage between sites across the state. Possibly because of the sample size, no statistically significant trends were observed between sites through the years 1890-1984. Several poorly defined single site jumps were observed in the precipitation record, however, these were not clearly linked to companion temperature perturbations

Unique Multiorganizational Collaborative Proves Effective in Delivering 2014 Farm Bill Education

The Agricultural Act of 2014 is critical to the economic safety net for U.S. producers. This act represented a major change in philosophy, requiring producers to make key decisions about their options on the basis of risk management. To add to the complexity of the issue, the time period for delivering applicable education to landowners before sign-up deadlines was relatively short. This article highlights a unique multiorganizational statewide approach to delivering the applicable education. It involved University of Minnesota Extension, the Center for Farm Financial Management, the U.S. Department of Agriculture, and banks and resulted in substantive evaluative outcomes

EFFECT OF WEIGHTED JUMP WARM-UP ON VERTICAL JUMP IN FEMALE VOLLEYBALL PLAYERS

Warm-ups which elicit a post activation potentiation (PAP) effect may increase performance in subsequent activities requiring strength and power. However, finding practical methods to best manipulate and exploit PAP remains elusive. Purpose: To determine if a warm-up that included weighted jumps would elicit a PAP effect and increase subsequent vertical jump (VJ) height. Methods: Ten female NCAA Division II volleyball players participated (age = 19.8 ± 1.8 yrs; mass = 71.7 ± 9.7 kg; ht = 167.8 ±23.9 cm). Two warm-up conditions were randomly employed: 1) light jogging, high knees, carioca, shuffling, ankle pops, pogos, and tuck jumps; and 2) an identical warm-up, plus 10 maximal VJs while wearing 20% of bodyweight. At 4-minutes post, VJ was randomly assessed in two conditions: 1) 2-hand standing block VJ (SBVJ), and 2) 1-hand 3-step approach VJ (AVJ). Paired Samples T-test determined if there was a significant difference (p < 0.05) in VJ height between the two conditions. Results: Results were mixed. No significant difference (p > 0.05) occurred in the SBVJ (262.1 vs. 263.0 cm, warm-up vs. warm-up with weight vest, respectively). However, the AVJ was significantly higher by 2.7±1.5 cm (p < 0.05; 275.1±13.2 vs. 277.8±13.2 cm) with the weight vest added to their warm-up. Conclusion: This study demonstrates that a dynamic warm-up with the addition of weighted jumps may increase 3-step AVJ ability in female collegiate volleyball players. However, no effect was seen in 2-hand SBVJ ability. Coaches may consider using a warm-up that includes weighted jumps to optimize performance in sports like volleyball where vertical jumps with an approach are key components of competition.  Article visualizations

Corn Tiller Yield Contributions and Ear Development in Low Plant Densities

Research in modern corn (Zea mays L.) hybrids investigating tiller contributions and ear development at low plant densities is scarce, particularly in water-limited environments. To fill this research gap, a second season of replicated experiments was conducted in 2020 at 7 sites across Kansas (Keats, Buhler, Greensburg, Garden City, Goodland, and two sites in Colby) evaluating two common, tiller-prone corn hybrids (P0805AM and P0657AM) at three target plant density levels (10000, 17000, and 24000 plants/a). Five of the listed sites also considered a tillering factor (tiller removal at development stage V10 [tenth-leaf] or tiller maintenance). Seasonal phenology, partitioned grain yield, harvested ear type characterizations, and environmental conditions were recorded and analyzed to quantify tiller contributions in each site. Results showed that intact tillers had either no effect or were able to boost yields. In the best environments, tillers were able to successfully compensate for losses of 60% in plant density. Five of the seven tested sites produced approximately 50% of total harvested ears as desirable tiller lateral ears in the 10000 plants/a target plant density. The highest percentage of undesirable tiller tassel ear development in the 10000 plants/a density was 13%. Future research will seek to find explanations of the ear type relationships on a deeper level and predict tiller yield contributions considering various environments and ear development outcomes

Liquid Flyback Booster Pre-Phase A Study Assessment

Mw concept of a flyback booster has been around since early in the Shuttle program. The original two-stage Shuttle concepts used a manned flyback booster. These boosters were eliminated from the program for funding and size reasons. The current Shuttle uses two Redesigned Solid Rocket Motors (RSRMs), which are recovered and refurbished after each flight; this is one of the major cost factors of the program. Replacement options have been studied over the past ten years. The conclusion reached by the most recent study is that the liquid flyback booster (LFBB) is the only competitive option from a life-cycle cost perspective. The purpose of this study was to assess the feasibility and practicality of LFBBs. The study provides an expansion of the recommendations made during the during the aforementioned study. The primary benefits are the potential for enhanced reusability and a reuction of recurring costs. The potential savings in vehicle turnaround could offset the up-front costs. Development of LFBBs requires a commitment to the Shuttle program for 20 to 30 years. LFBBs also offer enhanced safety and abort capabilities. Currently, any failure of an RSRM can be considered catastrophic since them we no intact abort capabilities during the burn of the RSRMS. The performance goal of the LFBBs was to lift a fully loaded Orbiter under optimal conditions, so as not to be the limiting factor of the performance capability of the Shuttle. In addition, a final benefit is the availability of growth paths for applications other than the Shuttle

CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2

Background: Ventricular arrhythmia and sudden cardiac death are the most common lethal complications after myocardial infarction. Antiarrhythmic pharmacotherapy remains a clinical challenge and novel concepts are highly desired. Here, we focus on the cardioprotective CNP (C-type natriuretic peptide) as a novel antiarrhythmic principle. We hypothesize that antiarrhythmic effects of CNP are mediated by PDE2 (phosphodiesterase 2), which has the unique property to be stimulated by cGMP to primarily hydrolyze cAMP. Thus, CNP might promote beneficial effects of PDE2-mediated negative crosstalk between cAMP and cGMP signaling pathways. Methods: To determine antiarrhythmic effects of cGMP-mediated PDE2 stimulation by CNP, we analyzed arrhythmic events and intracellular trigger mechanisms in mice in vivo, at organ level and in isolated cardiomyocytes as well as in human-induced pluripotent stem cell-derived cardiomyocytes. Results: In ex vivo perfused mouse hearts, CNP abrogated arrhythmia after ischemia/reperfusion injury. Upon high-dose catecholamine injections in mice, PDE2 inhibition prevented the antiarrhythmic effect of CNP. In mouse ventricular cardiomyocytes, CNP blunted the catecholamine-mediated increase in arrhythmogenic events as well as in ICaL, INaL, and Ca2+spark frequency. Mechanistically, this was driven by reduced cellular cAMP levels and decreased phosphorylation of Ca2+handling proteins. Key experiments were confirmed in human iPSC-derived cardiomyocytes. Accordingly, the protective CNP effects were reversed by either specific pharmacological PDE2 inhibition or cardiomyocyte-specific PDE2 deletion. Conclusions: CNP shows strong PDE2-dependent antiarrhythmic effects. Consequently, the CNP-PDE2 axis represents a novel and attractive target for future antiarrhythmic strategies

Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?

Objective: To assess changes in cannabis use in young adults as a function of psychotic-like experiences. Method: Participants were initially recruited at age 14 in high schools for the longitudinal IMAGEN study. All measures presented here were assessed at follow-ups at age 19 and at age 22, respectively. Perceived stress was only assessed once at age 22. Ever users of cannabis (N = 552) gave qualitative and quantitative information on cannabis use and psychotic-like experiences using the Community Assessment of Psychic Experiences (CAPE). Of those, nearly all n = 549 reported to have experienced at least one psychotic experience of any form at age 19. Results: Mean cannabis use increased from age 19 to 22 and age of first use of cannabis was positively associated with a change in cannabis use between the two time points. Change in cannabis use was not significantly associated with psychotic-like experiences at age 19 or 22. In exploratory analysis, we observed a positive association between perceived stress and the experience of psychotic experiences at age 22. Conclusion: Age of first use of cannabis influenced trajectories of young cannabis users with later onset leading to higher increase, whereas the frequency of psychotic-like experiences was not associated with a change in cannabis use. The observed association between perceived stress and psychotic-like experiences at age 22 emphasizes the importance of stress experiences in developing psychosis independent of cannabis use