Medias et biographie : Jean Vincent-Dolor, 40 ans de journalisme à la Réunion (1948-1987)

Dans une île en mutation rapide, mais pauvre en matériaux historiques sur la période contemporaine, l’approche biographique permet d’aborder l’analyse de l’évolution récente des médias. Le récit de vie d’un acteur clef, Jean Vincent-Dolor, qui en 40 ans de journalisme à la Réunion (1948-1987) a exercé une influence déterminante, notamment à la radio et à la télévision, apporte un éclairage sur les transformations en cours. Trois éléments principaux se dégagent du discours de JVD : 1) la perception du contexte socio-politique de l’époque, 2) la conception du rôle prévalent des médias dans leur capacité supposée à influencer les opinions et enfin, 3) un dualisme identitaire, propre aux décideurs locaux, « maîtres » chez eux, mais incompris à Paris.Qualitative approaches are useful to analyse the recent evolution of local medias in Reunion island. At the head of the State public radio and television in this French oversea territory, Jean Vincent-Dolor was an influent journalist from 1948 to 1987. He has been a central key actor for that crucial period. This paper deals with his life history throwing relevant light on changes in progress. Three main thematical aspects are set out here, issued from these biographical data : 1) his perception of the social and political former context ; 2) his conception of the dominant fonction of the media upon public opinion ; and 3) he expresses the dual identity — specific of the local decision makers in media area and others — , meaning a gap between the French national and gouvernemental sphere where he was told misunderstood and the island community within which he is perceived as one of the most powerful actor in media and political life

Identification sans contrainte de stationnarité d'un modèle AR d'une texture

Un problème classique en analyse d'image est d'obtenir une modélisation caractéristique d'images texturées. L'utilisation d'un modèle AR-2D fournit souvent des solutions efficaces. Cependant, l'identification des coefficients d'un tel modèle est assujettie à l'hypothèse de stationnarité du signal. Pour résoudre ce problème, nous considérons la distribution spatiale du signal générateur utilisé avec le modèle AR-2D. L'originalité de ce travail vient d'une identification simultanée des paramètres du modèle et des échantillons du générateur, ceci par un processus neuronal. Ainsi, comme résultats nouveaux, nous proposons une méthode permettant de représenter une texture par un couple d'attributs, un modèle AR-2D et une distribution spatiale du signal générateur

Vibrational properties of SrCu2O2 studied via Density Functional Theory calculations and compared to Raman and infrared spectroscopy measurements

International audienceThe SrCu2O2 material is a p-type transparent conductive oxide. A theoretical study of the SrCu2O2 crystal is performed with a state of the art implementation of the Density Functional Theory. The simulated crystal structure is compared with available X-ray diffraction data and previous theoretical modeling. Density Functional Perturbation Theory is used to study the vibrational properties of the SrCu2O2 crystal. A symmetry analysis of the optical phonon eigenvectors at the Brillouin zone center is proposed. The Raman spectra simulated using the derivatives of the dielectric susceptibility, show a good agreement with Raman scattering experimental results

Système permanent d'observation du triangle Lyon-Chambéry-Grenoble (Spot)

Le système permanent d'observation du triangle Lyon-Chambéry-Grenoble couvre une zone constituée par 245 communes de l'Ain, l'Isère et la Savoie, excluant les pôles, pointes du triangle. Le spot, organise sur l'unité d'observation communale, couvre, selon des informations élémentaires homogènes, l'ensemble des communes qui composent le tissu spatial. L'information communale étant considérée comme pertinente pour déceler en première instance les transformations économiques, sociales ou culturelles.banque de données ; observation communale ; méthodologie ; transformations économiques ; transformations sociales ; transformations culturelles ; Ain ; Isère ; Savoie

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

Tumor growth promotes the expansion of CD4+CD25+ regulatory T (T reg) cells that counteract T cell–mediated immune responses. An inverse correlation between natural killer (NK) cell activation and T reg cell expansion in tumor-bearing patients, shown here, prompted us to address the role of T reg cells in controlling innate antitumor immunity. Our experiments indicate that human T reg cells expressed membrane-bound transforming growth factor (TGF)–β, which directly inhibited NK cell effector functions and down-regulated NKG2D receptors on the NK cell surface. Adoptive transfer of wild-type T reg cells but not TGF-β−/− T reg cells into nude mice suppressed NK cell–mediated cytotoxicity, reduced NKG2D receptor expression, and accelerated the growth of tumors that are normally controlled by NK cells. Conversely, the depletion of mouse T reg cells exacerbated NK cell proliferation and cytotoxicity in vivo. Human NK cell–mediated tumor recognition could also be restored by depletion of T reg cells from tumor-infiltrating lymphocytes. These findings support a role for T reg cells in blunting the NK cell arm of the innate immune system

Genomic Exploration of the Hemiascomycetous Yeasts: 1. A set of yeast species for molecular evolution studies11Sequences and annotations are accessible at: Génoscope (http://www.genoscope.cns.fr), FEBS Letters Website (http://www.elsevier.nl/febs/show/), Bordeaux (http://cbi.genopole-bordeaux.fr/Genolevures) and were deposited into the EMBL database (accession number from AL392203 to AL441602).

AbstractThe identification of molecular evolutionary mechanisms in eukaryotes is approached by a comparative genomics study of a homogeneous group of species classified as Hemiascomycetes. This group includes Saccharomyces cerevisiae, the first eukaryotic genome entirely sequenced, back in 1996. A random sequencing analysis has been performed on 13 different species sharing a small genome size and a low frequency of introns. Detailed information is provided in the 20 following papers. Additional tables available on websites describe the ca. 20 000 newly identified genes. This wealth of data, so far unique among eukaryotes, allowed us to examine the conservation of chromosome maps, to identify the ‘yeast-specific’ genes, and to review the distribution of gene families into functional classes. This project conducted by a network of seven French laboratories has been designated ‘Génolevures’

Genomic Exploration of the Hemiascomycetous Yeasts: 19. Ascomycetes-specific genes

AbstractComparisons of the 6213 predicted Saccharomyces cerevisiae open reading frame (ORF) products with sequences from organisms of other biological phyla differentiate genes commonly conserved in evolution from ‘maverick’ genes which have no homologue in phyla other than the Ascomycetes. We show that a majority of the ‘maverick’ genes have homologues among other yeast species and thus define a set of 1892 genes that, from sequence comparisons, appear ‘Ascomycetes-specific’. We estimate, retrospectively, that the S. cerevisiae genome contains 5651 actual protein-coding genes, 50 of which were identified for the first time in this work, and that the present public databases contain 612 predicted ORFs that are not real genes. Interestingly, the sequences of the ‘Ascomycetes-specific’ genes tend to diverge more rapidly in evolution than that of other genes. Half of the ‘Ascomycetes-specific’ genes are functionally characterized in S. cerevisiae, and a few functional categories are over-represented in them

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men