Preferències dels estudiants en relació al tema d’estudi del TFG de Farmàcia (UB)

Podeu consultar la Vuitena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/66524El TFG del grau de farmàcia UB es porta a terme en el marc d’un àmbit docent principal i integra coneixements de com a mínim, dos àmbits docents addicionals atès la seva funció integradora. En el moment de definir les directrius i organització de l’assignatura, es van establir a la Facultat de Farmàcia 27 àmbits docents. Tanmateix, les característiques del TFG quan a tipus de projectes o estudis es van establir inicialment en base a tres opcions..

Systematic Collaborative Reanalysis of Genomic Data Improves Diagnostic Yield in Neurologic Rare Diseases

Altres ajuts: Generalitat de Catalunya, Departament de Salut; Generalitat de Catalunya, Departament d'Empresa i Coneixement i CERCA Program; Ministerio de Ciencia e Innovación; Instituto Nacional de Bioinformática; ELIXIR Implementation Studies (CNAG-CRG); Centro de Investigaciones Biomédicas en Red de Enfermedades Raras; Centro de Excelencia Severo Ochoa; European Regional Development Fund (FEDER).Many patients experiencing a rare disease remain undiagnosed even after genomic testing. Reanalysis of existing genomic data has shown to increase diagnostic yield, although there are few systematic and comprehensive reanalysis efforts that enable collaborative interpretation and future reinterpretation. The Undiagnosed Rare Disease Program of Catalonia project collated previously inconclusive good quality genomic data (panels, exomes, and genomes) and standardized phenotypic profiles from 323 families (543 individuals) with a neurologic rare disease. The data were reanalyzed systematically to identify relatedness, runs of homozygosity, consanguinity, single-nucleotide variants, insertions and deletions, and copy number variants. Data were shared and collaboratively interpreted within the consortium through a customized Genome-Phenome Analysis Platform, which also enables future data reinterpretation. Reanalysis of existing genomic data provided a diagnosis for 20.7% of the patients, including 1.8% diagnosed after the generation of additional genomic data to identify a second pathogenic heterozygous variant. Diagnostic rate was significantly higher for family-based exome/genome reanalysis compared with singleton panels. Most new diagnoses were attributable to recent gene-disease associations (50.8%), additional or improved bioinformatic analysis (19.7%), and standardized phenotyping data integrated within the Undiagnosed Rare Disease Program of Catalonia Genome-Phenome Analysis Platform functionalities (18%)

Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study.

Harmonizing clinical pharmacology and therapeutics (CPT) education in Europe is necessary to ensure that the prescribing competency of future doctors is of a uniform high standard. As there are currently no uniform requirements, our aim was to achieve consensus on key learning outcomes for undergraduate CPT education in Europe. We used a modified Delphi method consisting of three questionnaire rounds and a panel meeting. A total of 129 experts from 27 European countries were asked to rate 307 learning outcomes. In all, 92 experts (71%) completed all three questionnaire rounds, and 33 experts (26%) attended the meeting. 232 learning outcomes from the original list, 15 newly suggested and 5 rephrased outcomes were included. These 252 learning outcomes should be included in undergraduate CPT curricula to ensure that European graduates are able to prescribe safely and effectively. We provide a blueprint of a European core curriculum describing when and how the learning outcomes might be acquired

The Network Company in Catalonia : ICT, Productivity, Competitiveness, Salaries and Performance in Catalonia's Companies. Research report (synthesis document)

Resum en anglès del projecte de recerca L'empresa xarxa a Catalunya. TIC, productivitat, competitivitat, salaris i beneficis a l'empresa catalana té com a objectiu principal constatar que la consolidació d'un nou model estratègic, organitzatiu i d'activitat empresarial, vinculat amb la inversió i l'ús de les TIC (o empresa xarxa), modifica substancialment els patrons de comportament dels resultats empresarials, en especial la productivitat, la competitivitat, les retribucions dels treballadors i el benefici. La contrastació empírica de les hipòtesis de treball l'hem feta per mitjà de les dades d'una enquesta a una mostra representativa de 2.038 empreses catalanes. Amb la perspectiva de l'impacte de la inversió i l'ús de les TIC no s'aprecia una relació directa entre els processos d'innovació digital i els resultats de l'activitat de l'empresa catalana. En aquest sentit, hem hagut de segmentar el teixit productiu català per a buscar les organitzacions en què el procés de coinnovació tecnològica digital i organitzativa és més present i en què la intensitat de l'ús del coneixement és un recurs molt freqüent per a poder copsar impactes rellevants en els principals resultats empresarials. Això és així perquè l'economia catalana, avui, presenta una estructura productiva dual.Resumen en inglés del proyecto de investigación La empresa red en Catalunya. TIC, productividad, competitividad, salarios y beneficios en la empresa catalana tiene como objetivo principal constatar que la consolidación de un nuevo modelo estratégico, organizativo y de actividad empresarial, vinculado con la inversión y el uso de las TIC (o empresa red), modifica sustancialmente los patrones de comportamiento de los resultados empresariales, en especial la productividad, la competitividad, las retribuciones de los trabajadores y el beneficio. La contrastación empírica de las hipótesis de trabajo la hemos realizado mediante los datos de una encuesta a una muestra representativa de 2.038 empresas catalanas. Con la perspectiva del impacto de la inversión y el uso de las TIC no se aprecia una relación directa entre los procesos de innovación digital y los resultados de la actividad de la empresa catalana. En este sentido, hemos tenido que segmentar el tejido productivo catalán para buscar las organizaciones en las que el proceso de coinnovación tecnológica digital y organizativa está más presente y en las que la intensidad del uso del conocimiento es un recurso muy frecuente para poder captar impactos relevantes en los principales resultados empresariales. Eso es así porque la economía catalana, hoy, presenta una estructura productiva dual.Synthesis document of the research project The Network Company in Catalonia: ICT, Productivity, Competitiveness, Salaries and Performance in Catalonia's Companies, a project that tries to show that the consolidation of a new strategic, organisational and business activity model, linked to investment and the use of ICT (ie, the network company), significantly alters performance patterns where business results are concerned, particularly productivity, competitiveness, workers' wages and profit. We have empirically tested our working hypotheses using data from a survey conducted on a representative sample of 2,038 Catalan companies. With regard to the impact of investment and the use of ICT, there are no signs of a direct relationship between digital innovation processes and the operating results of Catalan companies. Indeed, we have had to segment Catalonia's productive fabric in search of those organisations with digital technology co-innovation and organisation processes, and frequent and intensive use of knowledge in order to find any significant impact on the main business results. This has been the case because the Catalan economy presently has a two-tier productive structure. On one hand, in the majority of the productive fabric (around 80%), where there is a low degree of ICT use, the level of qualifications of the workforce could clearly be improved, productive and organisational structures are inflexible and involve little in the way of autonomy or scope for workers to make decisions, and innovative processes are still infrequent. This group of companies has an extensive growth model; ie, its prospects for long-term expansion are based on an upturn in its factors, especially that of low-skilled workers. It is for this very reason that the rate of growth in productivity in Catalonia is at such worrying levels and, in a context of competition dominated by globalisation, what makes the problems of competitiveness so important. On the other hand, a smaller group of companies (around 20%) bases its potential for growth on the interaction of human capital, the reorientation of production and the organisation of work, and a constant dynamic of innovation, in terms of digital technology in particular, but also with respect to the management of human resources. It is this group of companies, a much smaller group than the former, but with much greater potential for growth in the long term, where positive evolution in terms of efficiency, competitiveness, salaries and the performance of our productive fabric can be identified

L'empresa xarxa a Catalunya : TIC, productivitat, competitivitat, salaris i rendiment a les empreses de Catalunya. Informe final de recerca (volum II)

El projecte de recerca L'empresa xarxa a Catalunya. TIC, productivitat, competitivitat, salaris i beneficis a l'empresa catalana té com a objectiu principal constatar que la consolidació d'un nou model estratègic, organitzatiu i d'activitat empresarial, vinculat amb la inversió i l'ús de les TIC (o empresa xarxa), modifica substancialment els patrons de comportament dels resultats empresarials, en especial la productivitat, la competitivitat, les retribucions dels treballadors i el benefici. La contrastació empírica de les hipòtesis de treball l'hem feta per mitjà de les dades d'una enquesta a una mostra representativa de 2.038 empreses catalanes. Amb la perspectiva de l'impacte de la inversió i l'ús de les TIC no s'aprecia una relació directa entre els processos d'innovació digital i els resultats de l'activitat de l'empresa catalana. En aquest sentit, hem hagut de segmentar el teixit productiu català per a buscar les organitzacions en què el procés de coinnovació tecnològica digital i organitzativa és més present i en què la intensitat de l'ús del coneixement és un recurs molt freqüent per a poder copsar impactes rellevants en els principals resultats empresarials. Això és així perquè l'economia catalana, avui, presenta una estructura productiva dual.El proyecto de investigación La empresa red en Catalunya. TIC, productividad, competitividad, salarios y beneficios en la empresa catalana tiene como objetivo principal constatar que la consolidación de un nuevo modelo estratégico, organizativo y de actividad empresarial, vinculado con la inversión y el uso de las TIC (o empresa red), modifica sustancialmente los patrones de comportamiento de los resultados empresariales, en especial la productividad, la competitividad, las retribuciones de los trabajadores y el beneficio. La contrastación empírica de las hipótesis de trabajo la hemos realizado mediante los datos de una encuesta a una muestra representativa de 2.038 empresas catalanas. Con la perspectiva del impacto de la inversión y el uso de las TIC no se aprecia una relación directa entre los procesos de innovación digital y los resultados de la actividad de la empresa catalana. En este sentido, hemos tenido que segmentar el tejido productivo catalán para buscar las organizaciones en las que el proceso de coinnovación tecnológica digital y organizativa está más presente y en las que la intensidad del uso del conocimiento es un recurso muy frecuente para poder captar impactos relevantes en los principales resultados empresariales. Eso es así porque la economía catalana, hoy, presenta una estructura productiva dual.The main aim of the research project The Network Company in Catalonia: ICT, Productivity, Competitiveness, Salaries and Performance in Catalonia's Companies is to show that the consolidation of a new strategic, organisational and business activity model, linked to investment and the use of ICT (ie, the network company), significantly alters performance patterns where business results are concerned, particularly productivity, competitiveness, workers' wages and profit. We have empirically tested our working hypotheses using data from a survey conducted on a representative sample of 2,038 Catalan companies. With regard to the impact of investment and the use of ICT, there are no signs of a direct relationship between digital innovation processes and the operating results of Catalan companies. Indeed, we have had to segment Catalonia's productive fabric in search of those organisations with digital technology co-innovation and organisation processes, and frequent and intensive use of knowledge in order to find any significant impact on the main business results. This has been the case because the Catalan economy presently has a two-tier productive structure. On one hand, in the majority of the productive fabric (around 80%), where there is a low degree of ICT use, the level of qualifications of the workforce could clearly be improved, productive and organisational structures are inflexible and involve little in the way of autonomy or scope for workers to make decisions, and innovative processes are still infrequent. This group of companies has an extensive growth model; ie, its prospects for long-term expansion are based on an upturn in its factors, especially that of low-skilled workers. It is for this very reason that the rate of growth in productivity in Catalonia is at such worrying levels and, in a context of competition dominated by globalisation, what makes the problems of competitiveness so important. On the other hand, a smaller group of companies (around 20%) bases its potential for growth on the interaction of human capital, the reorientation of production and the organisation of work, and a constant dynamic of innovation, in terms of digital technology in particular, but also with respect to the management of human resources. It is this group of companies, a much smaller group than the former, but with much greater potential for growth in the long term, where positive evolution in terms of efficiency, competitiveness, salaries and the performance of our productive fabric can be identified