909 research outputs found
A feeling for change: exploring the lived and unlived experiences of drivers to inform a transition to an electric automobility
Incidence of Postpartum Endomyometritis Following Single-Dose Antibiotic Prophylaxis With Either Ampicillin/Sulbactam, Cefazolin, or Cefotetan in High-Risk Cesarean Section Patients
Novel Wine Pouring Machine
This Final Design Report outlines the âNovel Wine Openerâ senior design project completed by a team of mechanical engineering students at California Polytechnic State University, San Luis Obispo. The project was sponsored by Bill Swanson, owner of the Center of Effort vineyard and winery in Edna Valley, CA. The goal of the project was to produce a novel wine pouring machine for the Center of Effort. This device should be able to remove the foil cap from a wine bottle, uncork the bottle, and pour a glass of wine at the winery and at public events. The finished product should fit the aesthetic of the remodeled winery and serve as an attraction for wine tasting visitors. After determining our sponsorâs needs and wants for the project, we refined the problem into a set of engineering specifications. Existing technologies were researched and compared to identify similar developments already on the market. The lack of similar technologies found confirmed the presence of a need that our project seeks to fill. The first step we took in tackling this design challenge was to divide the project into six subsystems: bottle gripping, foil removal, cork removal, lifting and pouring, pour volume sensing, and user interface. Our leading concepts comprise a rotating tower for foil and cork removal, a pivoting pouring tower to hold and pour the bottle, a load cell to measure the pour volume, and mechanical buttons and toggle switches for user interface. To verify the feasibility of our designs, we built conceptual and structural prototypes of the rotating tower, cork remover, and foil cutter. The next step in the design process was to redesign each individual function as needed. Prototyping highlighted areas in need of design changes. These changes were implemented, and new prototypes were made. This cycle continued until each individual function operated successfully. The final design consists of improved versions of the leading concepts selected before prototyping: rotating tower, pouring tower, bottle gripper, load cell weight sensing mechanism, and user interface. Next, the final design was manufactured and assembled with final materials. Most prototyping materials included plywood and acrylic. These materials were switched out with aluminum parts. After each function was successfully manufactured and functional, all subsystems were integrated together onto one base plate. Some redesigning and remanufacturing were necessary for successful integration of the entire device. Once the device was satisfactorily assembled, the device was tested against the engineering specifications originally identified at the beginning of the project. This document contains the research, ideation processes, design decisions, design outcomes, manufacturing processes, and test results of the entire process to date
Local status and power in area-based health improvement partnerships
This is the authors' PDF version of an article published in Health© 2014. The definitive version is available at http://hea.sagepub.comArea-based initiatives (ABIs) have formed an important part of public policy towards more socio-economically deprived areas in many countries. Co-ordinating service provision within and across sectors has been a common feature of these initiatives. Despite sustained policy interest in ABIs, little empirical work has explored relations between ABI providers and partnership development within this context remains under-theorised. This paper addresses both of these gaps by exploring partnerships as a social and developmental process, drawing on concepts from figurational sociology to explain how provider relations develop within an ABI. Qualitative methods were used to explore, prospectively, the development of an ABI targeted at a town in the north west of England. A central finding was that, although effective delivery of ABIs is premised on a high level of coordination between service providers, the pattern of interdependencies between providers limits the frequency and effectiveness of cooperation. In particular, the interdependency of ABI providers with others in their organisation (what is termed here âorganisational pullâ) constrained the ways in which they worked with providers outside of their own organisations. âLocalâ status, which could be earned over time, enabled some providers to exert greater control over the way in which provider relations developed during the course of the initiative. These findings demonstrate how historically constituted social networks, within which all providers are embedded, shape partnership development. The theoretical insight developed here suggests a need for more realistic expectations among policy makers about how and to what extent provider partnerships can be managed. Keywords: partnership, collaboration, community services, area-based initiatives, organisational pull, figurational sociologyNational Health Service (NHS
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Guidelines to improve airport preparedness against chemical and biological terrorism.
Guidelines to Improve Airport Preparedness Against Chemical and Biological Terrorism is a 100-page document that makes concrete recommendations on improving security and assessing vulnerable areas and helps its readers understand the nature of chemical and biological attacks. The report has been turned over to Airports Council International (ACI) and the American Association of Airport Executives (AAAE), two organizations that together represent the interests of thousands of airport personnel and facilities in the U.S. and around the world
TRANSPERSONAL PSYCHOLOGY, SCIENCE, AND THE SUPERNATURAL
ABSTRACT: This article critically discusses the scientific status of transpersonal psychology and its relation to so-called supernatural claims. In particular, analysis focuses o
Monte Carlo Comparisons to a Cryogenic Dark Matter Search Detector with low Transition-Edge-Sensor Transition Temperature
We present results on phonon quasidiffusion and Transition Edge Sensor (TES)
studies in a large, 3 inch diameter, 1 inch thick [100] high purity germanium
crystal, cooled to 50 mK in the vacuum of a dilution refrigerator, and exposed
with 59.5 keV gamma-rays from an Am-241 calibration source. We compare
calibration data with results from a Monte Carlo which includes phonon
quasidiffusion and the generation of phonons created by charge carriers as they
are drifted across the detector by ionization readout channels. The phonon
energy is then parsed into TES based phonon readout channels and input into a
TES simulator
The Role of Chinese Cities in Greenhouse Gas Emission Reduction
Currently, 3.9 billion people live in cities, representing 54% of the worldâs population.1 Cities, as hubs of fossil fuel-based economic activity, emit over 70% of global energy-related greenhouse gas (GHG) emissions. The worldâs 50 largest cities are collectively the third largest emitter of energy-related GHGs, after China and the U.S.2 In many North American cities, transportation accounts for the largest share of emissions, while industry and buildings are major sources in many Asian cities. The rate of urbanization is accelerating in the world\u27s most populous countries, with associated rapid and high-volume production of energy- and carbon-intensive building materials to construct urban infrastructure.
Impacts of climate change are already being experienced in cities, from severe storms damaging infrastructure, to droughts and floods, intensified heat waves, worsening smog, and other ecological and human health impacts.3 Nearly 80 million Chinese city dwellers live in coastal zones at risk for sea-level rise, compared to 30 million in India and 20 million in the U.S.4 Both as drivers of climate change and sites vulnerable to climate impacts, cities are at the forefront of pursuing energy-efficient and low carbon development
Patients Prescribed Direct-acting Oral Anticoagulants Have Low Risk of Post-Polypectomy Complications
Background & Aims
Use of direct-acting oral anticoagulants (DOACs) is increasing, but little is known about the associated risks in patients undergoing colonoscopy with polypectomy. We aimed to determine the risk of post-polypectomy complications in patients prescribed DOACs.
Methods
We performed a retrospective analysis using the Clinformatics Data Mart Database (a de-identified administrative database from a large national insurance provider) to identify adults who underwent colonoscopy with polypectomy or endoscopic mucosal resection (EMR) from January 1, 2011, through December 31, 2015. We collected data from 11,504 patients prescribed antithrombotic agents (1590 DOAC, 3471 warfarin, and 6443 clopidogrel) and 599,983 patients not prescribed antithrombotics of interest (controls). We compared 30-day post-polypectomy complications, including gastrointestinal bleeding (GIB), cerebrovascular accident (CVA), myocardial infarction (MI), and hospital admissions, of patients prescribed DOACs, warfarin, or clopidogrel vs controls.
Results
Post-polypectomy complications were uncommon but occurred in a significantly higher proportion of patients receiving any antithrombotic vs controls (P<0.001). The percentage of patients in the DOAC group with GIB was 0.63% (95% CI, 0.3%â1.2%) vs 0.2% (95% CI, 0.2%â0.3%) in controls. The percentage of patients with CVA in the DOAC group was 0.06% (95% CI, 0.01%â0.35%) vs 0.04% (95% CI, 0.04%â0.05%) in controls. After we adjusted for bridge anticoagulation, EMR, Charlson comorbidity index (CCI), and CHADS2 (congestive heart failure, hypertension, age over 75, diabetes, stroke [double weight]) score, patients prescribed DOACs no longer had a statistically significant increase in the odds of GIB (odds ratio [OR], 0.90; 95% CI, 0.44â1.85), CVA (OR, 0.45; 95% CI, 0.06â3.28), MI (OR, 1.07; 95% CI, 0.14â7.72), or hospital admission (OR, 0.86; 95% CI, 0.64â1.16). Clopidogrel, warfarin, bridge anticoagulation, higher CHADS2, CCI, and EMR were associated with increased odds of complications.
Conclusion
In our retrospective analysis of a large national dataset, we found that patients prescribed DOACs did not have significantly increased adjusted odds of post-polypectomy GIB, MI, CVA, or hospital admission. Bridge anticoagulation, higher CHADS2 score, CCI, and EMR were risk factors for GIB, MI, CVA, and hospital admissions. Studies are needed to determine the optimal peri-procedural dose for high-risk patients
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