4,596 research outputs found
Postirradiation behavior of p-channel charge-coupled devices irradiated at 153 K
The displacement damage hardness that can be achieved using p-channel charge-coupled devices (CCD) was originally demonstrated in 1997, and since then a number of other studies have demonstrated an improved tolerance to radiation-induced CTI when compared to n-channel CCDs. A number of recent studies have also shown that the temperature history of the device after the irradiation impacts the performance of the detector, linked to the mobility of defects at different temperatures. This study describes the initial results from an e2v technologies p-channel CCD204 irradiated at 153 K with a 10 MeV equivalent proton fluences of 1.24×109 and 1.24×1011 protons cm-2. The dark current, cosmetic quality and the number of defects identified using trap pumping immediately were monitored after the irradiation for a period of 150 hours with the device held at 153 K and then after different periods of time at room temperature. The device also exhibited a flatband voltage shift of around 30 mV / krad, determined by the reduction in full well capacity
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Simultaneous Measurements of Atmospheric HONO and NO2 via Absorption Spectroscopy using Tunable Mid-Infrared Continuous-wave Quantum Cascade Lasers
Nitrous acid (HONO) is important as a significant source of hydroxyl radical (OH) in the troposphere and as a potent indoor air pollutant. It is thought to be generated in both environments via heterogeneous reactions involving nitrogen dioxide . In order to enable fast-response HONO detection suitable for eddy-covariance flux measurements and to provide a direct method that avoids interferences associated with derivatization, we have developed a 2-channel tunable infrared laser differential absorption spectrometer (TILDAS) capable of simultaneous high-frequency measurements of HONO and NO2. Beams from two mid-infrared continuous-wave mode quantum cascade lasers (cw-QCLs) traverse separate 210 m paths through a multi-pass astigmatic sampling cell at reduced pressure for the direct detection of HONO and . The resulting one-second detection limits (S/N=3) are 300 and 30 ppt (pmol/mol) for HONO and , respectively. Our HONO quantification is based on revised line-strengths and peak positions for cis-HONO in the 6-micron spectral region that were derived from laboratory measurements. An essential component of ambient HONO measurements is the inlet system and we demonstrate that heated surfaces and reduced pressure minimize sampling artifacts.Earth and Planetary SciencesEngineering and Applied Science
Fatigue evaluation in maintenance and assembly operations by digital human simulation
Virtual human techniques have been used a lot in industrial design in order
to consider human factors and ergonomics as early as possible. The physical
status (the physical capacity of virtual human) has been mostly treated as
invariable in the current available human simulation tools, while indeed the
physical capacity varies along time in an operation and the change of the
physical capacity depends on the history of the work as well. Virtual Human
Status is proposed in this paper in order to assess the difficulty of manual
handling operations, especially from the physical perspective. The decrease of
the physical capacity before and after an operation is used as an index to
indicate the work difficulty. The reduction of physical strength is simulated
in a theoretical approach on the basis of a fatigue model in which fatigue
resistances of different muscle groups were regressed from 24 existing maximum
endurance time (MET) models. A framework based on digital human modeling
technique is established to realize the comparison of physical status. An
assembly case in airplane assembly is simulated and analyzed under the
framework. The endurance time and the decrease of the joint moment strengths
are simulated. The experimental result in simulated operations under laboratory
conditions confirms the feasibility of the theoretical approach
Security and Privacy Issues in Wireless Mesh Networks: A Survey
This book chapter identifies various security threats in wireless mesh
network (WMN). Keeping in mind the critical requirement of security and user
privacy in WMNs, this chapter provides a comprehensive overview of various
possible attacks on different layers of the communication protocol stack for
WMNs and their corresponding defense mechanisms. First, it identifies the
security vulnerabilities in the physical, link, network, transport, application
layers. Furthermore, various possible attacks on the key management protocols,
user authentication and access control protocols, and user privacy preservation
protocols are presented. After enumerating various possible attacks, the
chapter provides a detailed discussion on various existing security mechanisms
and protocols to defend against and wherever possible prevent the possible
attacks. Comparative analyses are also presented on the security schemes with
regards to the cryptographic schemes used, key management strategies deployed,
use of any trusted third party, computation and communication overhead involved
etc. The chapter then presents a brief discussion on various trust management
approaches for WMNs since trust and reputation-based schemes are increasingly
becoming popular for enforcing security in wireless networks. A number of open
problems in security and privacy issues for WMNs are subsequently discussed
before the chapter is finally concluded.Comment: 62 pages, 12 figures, 6 tables. This chapter is an extension of the
author's previous submission in arXiv submission: arXiv:1102.1226. There are
some text overlaps with the previous submissio
Olfaction in Parkin single and compound heterozygotes in a cohort of young onset Parkinson's disease patients
Background
Parkin related Parkinson's disease (PD) is differentiated from idiopathic PD by absent or sparse Lewy bodies, and preserved olfaction. The significance of single Parkin mutations in the pathogenesis of PD is debated.
Objectives
To assess olfaction results according to Parkin mutation status. To compare the prevalence of Parkin single heterozygous mutations in patients diagnosed with PD to the rate in healthy controls in order to establish whether these single mutations could be a risk factor for developing PD.
Methods
Parkin gene mutation testing was performed in young onset PD (diagnosed <50 years old) to identify three groups: Parkin homozygous or compound heterozygote mutation carriers, Parkin single heterozygote mutation carriers, and non-carriers of Parkin mutations. Olfaction was tested using the 40-item British version of the University of Pennsylvania smell identification test (UPSIT).
Results
Of 344 young onset PD cases tested, 8 (2.3%) were Parkin compound heterozygotes and 13 (3.8%) were Parkin single heterozygotes. Olfaction results were available in 282 cases (eight compound heterozygotes, nine single heterozygotes, and 265 non-carriers). In Parkin compound heterozygotes, the median UPSIT score was 33, interquartile range (IQR) 28.5–36.5, which was significantly better than in single Parkin heterozygotes (median 19, IQR 18–28) and non-carriers (median score 22, IQR 16–28) (ANOVA P < 0.001). These differences persisted after adjusting for age, disease duration, gender, and smoking (P < 0.001). There was no significant difference in UPSIT scores between single heterozygotes and non-carriers (P = 0.90).
Conclusions
Patients with Parkin compound heterozygous mutations have relatively preserved olfaction compared to Parkin single heterozygotes and non-carriers. The prevalence of Parkin single heterozygosity is similar to the 3.7% rate reported in healthy controls
Possible origins of macroscopic left-right asymmetry in organisms
I consider the microscopic mechanisms by which a particular left-right (L/R)
asymmetry is generated at the organism level from the microscopic handedness of
cytoskeletal molecules. In light of a fundamental symmetry principle, the
typical pattern-formation mechanisms of diffusion plus regulation cannot
implement the "right-hand rule"; at the microscopic level, the cell's
cytoskeleton of chiral filaments seems always to be involved, usually in
collective states driven by polymerization forces or molecular motors. It seems
particularly easy for handedness to emerge in a shear or rotation in the
background of an effectively two-dimensional system, such as the cell membrane
or a layer of cells, as this requires no pre-existing axis apart from the layer
normal. I detail a scenario involving actin/myosin layers in snails and in C.
elegans, and also one about the microtubule layer in plant cells. I also survey
the other examples that I am aware of, such as the emergence of handedness such
as the emergence of handedness in neurons, in eukaryote cell motility, and in
non-flagellated bacteria.Comment: 42 pages, 6 figures, resubmitted to J. Stat. Phys. special issue.
Major rewrite, rearranged sections/subsections, new Fig 3 + 6, new physics in
Sec 2.4 and 3.4.1, added Sec 5 and subsections of Sec
The WiggleZ Dark Energy Survey: Survey Design and First Data Release
The WiggleZ Dark Energy Survey is a survey of 240,000 emission line galaxies
in the distant universe, measured with the AAOmega spectrograph on the 3.9-m
Anglo-Australian Telescope (AAT). The target galaxies are selected using
ultraviolet photometry from the GALEX satellite, with a flux limit of NUV<22.8
mag. The redshift range containing 90% of the galaxies is 0.2<z<1.0. The
primary aim of the survey is to precisely measure the scale of baryon acoustic
oscillations (BAO) imprinted on the spatial distribution of these galaxies at
look-back times of 4-8 Gyrs. Detailed forecasts indicate the survey will
measure the BAO scale to better than 2% and the tangential and radial acoustic
wave scales to approximately 3% and 5%, respectively.
This paper provides a detailed description of the survey and its design, as
well as the spectroscopic observations, data reduction, and redshift
measurement techniques employed. It also presents an analysis of the properties
of the target galaxies, including emission line diagnostics which show that
they are mostly extreme starburst galaxies, and Hubble Space Telescope images,
which show they contain a high fraction of interacting or distorted systems. In
conjunction with this paper, we make a public data release of data for the
first 100,000 galaxies measured for the project.Comment: Accepted by MNRAS; this has some figures in low resolution format.
Full resolution PDF version (7MB) available at
http://www.physics.uq.edu.au/people/mjd/pub/wigglez1.pdf The WiggleZ home
page is at http://wigglez.swin.edu.au
The Sloan Digital Sky Survey-II Supernova Survey: Search Algorithm and Follow-up Observations
The Sloan Digital Sky Survey-II Supernova Survey has identified a large
number of new transient sources in a 300 sq. deg. region along the celestial
equator during its first two seasons of a three-season campaign. Multi-band
(ugriz) light curves were measured for most of the sources, which include solar
system objects, Galactic variable stars, active galactic nuclei, supernovae
(SNe), and other astronomical transients. The imaging survey is augmented by an
extensive spectroscopic follow-up program to identify SNe, measure their
redshifts, and study the physical conditions of the explosions and their
environment through spectroscopic diagnostics. During the survey, light curves
are rapidly evaluated to provide an initial photometric type of the SNe, and a
selected sample of sources are targeted for spectroscopic observations. In the
first two seasons, 476 sources were selected for spectroscopic observations, of
which 403 were identified as SNe. For the Type Ia SNe, the main driver for the
Survey, our photometric typing and targeting efficiency is 90%. Only 6% of the
photometric SN Ia candidates were spectroscopically classified as non-SN Ia
instead, and the remaining 4% resulted in low signal-to-noise, unclassified
spectra. This paper describes the search algorithm and the software, and the
real-time processing of the SDSS imaging data. We also present the details of
the supernova candidate selection procedures and strategies for follow-up
spectroscopic and imaging observations of the discovered sources.Comment: Accepted for publication in The Astronomical Journal (66 pages, 13
figures); typos correcte
A meta-analytic review of stand-alone interventions to improve body image
Objective
Numerous stand-alone interventions to improve body image have been developed. The
present review used meta-analysis to estimate the effectiveness of such interventions, and
to identify the specific change techniques that lead to improvement in body image.
Methods
The inclusion criteria were that (a) the intervention was stand-alone (i.e., solely focused on
improving body image), (b) a control group was used, (c) participants were randomly
assigned to conditions, and (d) at least one pretest and one posttest measure of body
image was taken. Effect sizes were meta-analysed and moderator analyses were conducted.
A taxonomy of 48 change techniques used in interventions targeted at body image
was developed; all interventions were coded using this taxonomy.
Results
The literature search identified 62 tests of interventions (N = 3,846). Interventions produced
a small-to-medium improvement in body image (d+ = 0.38), a small-to-medium reduction in
beauty ideal internalisation (d+ = -0.37), and a large reduction in social comparison tendencies
(d+ = -0.72). However, the effect size for body image was inflated by bias both within
and across studies, and was reliable but of small magnitude once corrections for bias were
applied. Effect sizes for the other outcomes were no longer reliable once corrections for
bias were applied. Several features of the sample, intervention, and methodology moderated
intervention effects. Twelve change techniques were associated with improvements in
body image, and three techniques were contra-indicated.
Conclusions
The findings show that interventions engender only small improvements in body image, and
underline the need for large-scale, high-quality trials in this area. The review identifies effective
techniques that could be deployed in future interventions
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