Evaluasi Kinerja Angkutan Umum Trayek Terminal Oebobo - Terminal Kupang Pp Dan Terminal Kupang - Terminal Noelbaki Pp

Beberapa ruas jalan pada Trayek Terminal Oebobo-Terminal Kupang PP dan trayek Terminal Kupang-Terminal Noelbaki PP, pada jam-jam puncak angkutan umum yang ada cenderung digunakan melebihi kapasitas maksimumnya. Keadaan sebaliknya terjadi pada jam non-puncak, kendaraan umum setengah kosong dan harus melakukan kompetisi dengan angkutan umum lainnya untuk mendapatkan penumpang. Tujuan dari penelitian adalah mengetahui kinerja pelayanan angkutan umum, kebutuhan angkutan umum dan membuat rekomendasi terkait dengan hasil evaluasi kinerja pelayanan pada kedua trayek ini. Dalam penelitian ini indikator kinerja angkutan umum yang dinilai adalah faktor muat, waktu perjalanan, frekuensi pelayanan, waktu antara, waktu tunggu, jumlah kendaraan yang beroperasi, dan waktu pelayanan. Indikator-indikator tersebut diperoleh dari hasil survey dinamis dan survey statis. Dari hasil evaluasi standar pelayanan angkutan umum menurut Dirjen Perhubungan Darat, kinerja pelayanan angkutan umum pada trayek Terminal Oebobo-Terminal Kupang PP dan Terminal Kupang-Terminal Noelbaki PP termasuk kategori baik. Kebutuhan jumlah angkutan umum pada trayek Terminal Oebobo-Terminal Kupang PP adalah 22 unit, sedangkan untuk trayek Terminal Kupang-Terminal Noelbaki PP sebanyak 40 unit. Berdasarkan hasil evaluasi diberikan rekomendasi diantaranya: jumlah angkutan umum yang sudah ada dipertahankan saja atau dikurangi hingga mendekati nilai rata-rata jumlah kendaraan beroperasi setiap hari serta perlunya pembinaan pada pengemudi tentang kesadaran berlalu lintas yang baik di jalan raya. Sometimes in Oebobo Station-Kupang Station route and Kupang Station-Noelbaki Station route, over capacity for public transportation happened in the peak time especially in several roads. While, in peak off time, most of public transportation have no passanger, so they had to compotate with the other transportation the get the passanger. Service operational planning of public transportation should be evaluate as soon as possible to know how about the performance of public transportation services. The goal of this research are to know about public transportation services performance, fleet necessity of public transportation and make recommendations relating to the results of the performance evaluation of services on this route both. The indicators of this research are public transportation performance, load factor, time journey, frequency, time line, passenger time waiting, the quantity of vehicle operated, and time services. All of these indicators get from dinamyc and statistic survey. From the results of the public transport service standards evaluation by the Directorate General of Land Transportation, the performance of public transport services on the Oebobo Station-Kupang Station Route and Kupang Station-Noelbaki Station Route including good categories. The needs of public transport fleet on the Oebobo Station-Kupang Station Route is 22 units, whereas for Kupang Station-Noelbaki Station Route 40 units. Based on the results of the evaluation given recommendations are: for while the number of existing public transport or retained only if necessary, be reduced to close to the average value of the number vehicles in operation each day as well as the need for guidance drivers about traffic awareness good on the highway

Validation of results of two different reductions for precision seamless cold drawn tubes

This paper deals with the comparison of the seamless pulling process of precision seamless tubes using two different reductions from the viewpoint of geometrical stability using computerized tomography, from the point of view of mechanical properties, from the point of view of the surface temperature in the arrangement of the tribological tube-tool pair. Validation of the pipe drawing process also took place based on the finite element method in the simulation program DEFORM 3D. From the point of view of production rationalization, it is necessary to analyze stress and deformation states at different input dimensions for a particular final dimension for a given drawing method, in this case, a drawing whiteout plug method was used

Trapping and patterning of biological objects using photovoltaic tweezers

Photovoltaic tweezers are a recently proposed technique for manipulation and patterning of micro- and nano-objects. It is based in the dielectrophoretic forces associated to the electric fields induced by illumination of certain ferroelectrics due to the bulk photovoltaic effect. The technique has been applied to the patterning of dielectric and metal micro- and nano-particles. In this work, we report the use of photovoltaic tweezers to pattern biological objects on LiNbO3:Fe. Specifically, spores and pollen grains and their nanometric fragments have been trapped and patterned. 1D and 2D arrangements have been achieved by deposition in air or from a hexane suspension. The quality of patterns obtained with nanometric fragments is even better than previous results using photovoltaic tweezers with inorganic micro- and nano-particles. In fact, 1D patterns with a period of 2 μm, almost half of the minimum reported period achieved with photovoltaic tweezers, have been obtained with pollen fragmentsThis work was supported by Spanish projects MAT2011-28379-C03 and MAT2014-57704-C0

The Potential of Ciplukan Leaf Extract (Physalis Angulata L.) to Improve Kidney Function

Gagal ginjal merupakan penyakit tidak menular namun dapat mengancam nyawa manusia. Penyakit ini dapat dialami dari berbagai macam usia mulai dari anak-anak hingga lansia. Salah satu tanaman yang biasanya dijadikan sebagai obat herbal ialah tanaman ciplukan (Physalis angulata L.). Gagal ginjal merupakan penyakit tidak menular namun dapat mengancam nyawa manusia. Penyakit ini dapat dialami dari berbagai macam usia mulai dari anak-anak hingga lansia. Salah satu tanaman yang biasanya dijadikan sebagai obat herbal ialah tanaman ciplukan (Physalis angulata L.). Penelitian ini bertujuan untuk mengetahui potensi dari daun tanaman ciplukan dalam memperbaiki fungsi ginjal. Penelitian ini dilakukan di Kampus IPB Dramaga, IPB University, Bogor. Tikus putih digunakan sebanyak 24 ekor dan dibagi menjadi 8 kelompok dengan perlakuan dosis 150mg/kg BB dan 300mg/kg BB. Perlakuan dilakukan selama 14 hari dan 28 hari.Etilen glikol digunakan sebagai agen nefrotoksik. Pemberian kombinasi etilen glikol 1 ml/100g BW secara oral dan ekstrak ciplukan dosis 300mg/kg BB secara bersamaan mampu menormalkan kadar ureum dalam darah. Hasil histologi juga menunjukkan adanya perbaikan pada glomerulus ginjal. Ekstrak daun ciplukan memiliki kandungan flavonoid yang berpotensi memperbaiki fungsi dan morfologi ginjal

Large Scale Control of Deferrable Domestic Loads in Smart Grids

In this paper, we investigate a realistic and low- cost deployment of large scale direct control of inelastic home appliances whose energy demand cannot be shaped, but simply deferred. The idea is to exploit 1) some simple actuators to be placed on the electric plugs for connecting or disconnecting appliances with heterogeneous control interfaces, including non- smart appliances, and 2) the Internet connections of customers for transporting the activation requests from the actuators to a centralized controller. Our solution requires no interaction with home users: in particular, it does not require them to express their energy demand in advance. A queuing theory model is derived to quantify how many users should adopt this solution in order to control a significant aggregated power load without significantly impairing their quality of service

Amphiregulin contained in NSCLC-exosomes induces osteoclast differentiation through the activation of EGFR pathway

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths worldwide. The majority of patients are diagnosed in advanced disease stage. Bone metastasis is the most frequent complication in NSCLC resulting in osteolytic lesions. The perfect balance between bone-resorbing osteoclasts and bone-forming osteoblasts activity is lost in bone metastasis, inducing osteoclastogenesis. In NSCLC, the epidermal growth factor receptor (EGFR) pathway is constitutively activated. EGFR binds Amphiregulin (AREG) that is overexpressed in several cancers such as colon, breast and lung. Its levels in plasma of NSCLC patients correlate with poor prognosis and AREG was recently found as a signaling molecule in exosomes derived from cancer cell lines. Exosomes have a key role in the cell-cell communication and they were recently indicated as important actors in metastatic niche preparation. In the present work, we hypothesize a role of AREG carried by exosomes derived from NSCLC in bone metastasis induction. We observed that NSCLC-exosomes, containing AREG, induce EGFR pathway activation in pre-osteoclasts that in turn causes an increased expression of RANKL. RANKL is able to induce the expression of proteolytic enzymes, well-known markers of osteoclastogenesis, triggering a vicious cycle in osteolytic bone metastasis

Percepción de estudiantes, sobre las implicancias éticas de las prácticas clínicas odontológicas durante su formación de grado

El odontólogo como profesional de la salud, para responder en forma integral a las necesidades sociales, debe disponer, no sólo de “un saber saber” y un “saber hacer”, sino también de un "saber ser", en el desempeño profesional. La formación universitaria aporta al desarrollo moral en el que se afianza la práctica profesional. El presente trabajo tuvo como objetivo conocer la percepción de estudiantes, sobre las implicancias éticas de las prácticas clínicas odontológicas durante su formación de grado. Desde un abordaje cualitativo se indagó sobre situaciones o experiencias vivenciadas por estudiantes durante el trayecto formativo de la práctica clínica odontológica, en que se hayan planteado conflictos o dilemas éticos y aspectos relacionados Se realizaron entrevistas en profundidad a estudiantes que durante 2018, cursaban el ciclo profesional de la carrera de odontología de la UNC. El análisis de la información realizado por el método comparativo constante, puso en evidencia que durante algunas prácticas clínicas se presentan situaciones de implicancia ética, que se resuelven frecuentemente, sin sustento teórico ni metodológico, de manera fortuita priorizando la exigencia académica. La capacitación docente en el área de bioética, podría fortalecer una formación más reflexiva e integral, que incluya competencias para tomar decisiones basadas en saberes éticosEspecialización en Docencia Universitari

Case report: Molecular detection of dirofilaria repens in an italian patient after a stay in tanzania

A 35-year-old man was admitted to a hospital in the south of Italy because of a periocular nodule and subpalpebral edema. The patient reported having been stayed in Tanzania five months before. Hematologic parameters were within the normality range, the Acanthocheilonema viteae ELISA did not detect significant levels of antifilarial IgG, and no further symptoms were described. The surgical inspection of the nodule led to the isolation of two filarioid parasites, identified as Dirofilaria repens by scanning electron microscope (SEM), and then by molecular assays. Knott's test did not reveal microfilaremia, whereas loop-mediated isothermal amplification andPCRdetected D. repens DNA. The patient was treated with doxycycline, and he was found no more positive at the follow-up

A search for heavy Kaluza-Klein electroweak gauge bosons at the LHC

The feasibility for the observation of a certain leptonic Kaluza-Klein (KK) hard process in {\em pp} interactions at the LHC is presented. Within the $S^1/Z_2$ TeV$^{-1}$ extra dimensional theoretical framework with the focus on the KK excitations of the Standard Model $\gamma$ and $Z^0$ gauge bosons, the hard-process, $f\bar f \to \sum_n\left(\gamma^*/Z^*\right)_n \to F \bar F$, has been used where $f$ is the initial state parton, $F$ the final state lepton and $\left(\gamma^*/Z^*\right)_{n}$ is the $n^{\rm th}$ KK excitation of the $\gamma/Z^0$ boson. For this study the analytic form for the hard process cross section has been independently calculated by the authors and has been implemented using the {\sc Moses} framework. The Moses framework itself, that has been written by the authors, was used as an external process within the {\sc Pythia} Monte Carlo generator which provides the phase space generation for the final state leptons and partons from the initial state hadrons, and the simulation of initial and final state radiation and hadronization. A brief discussion of the possibility for observing and identifying the unique signature of the KK signal given the current LHC program is also presented.Comment: 16 pages 10 figures, MCnet number: MCnet/10/06, Accepted by JHE