Does This Bag Make Me Look Good? The Impact of Post-Consumption Emotions on Re-Purchase Intention of Counterfeit Luxury Products

Individuals often consume products as a means of expressing themselves to those they interact with. Previous studies demonstrate that consumers use branded products to enhance their self-identity, highlight individuality, and increase social approval. (Geiger-Oneto et al., 2013), which is evident particularly in luxury consumption behavior (Vigneron & Johnson, 1999). As previous studies focused on examining predictors of luxury purchase intention (e.g., Bian & Forsythe, 2012), this study is interested in how consumers\u27 post-purchase emotions influence their intention of re-purchasing a luxury counterfeit. In addition, this study proposes that the effects of goal incongruence on aroused emotions are contingent upon the agent who causes the emotions (i.e., self, others) This study adopts emotion theory and appraisal theories as conceptual framework to examine a study phenomenon of interest. Our findings demonstrated that different post-consumption emotions are generated differently depending on the causation agent. Results, discussion and implications are presented

Can Fear Stop Animal Cruelty in Fashion Industry? The Effect of Negative Arousal in a Nonprofit Organization’s Social Media Campaigns

This study focuses on the issue of animal cruelty which is a relatively under-investigated topic in the fashion industry and aims to investigate how different levels of animal cruelty depicted in nonprofit organizations’ ethical consumption campaigns translate into viewers’ negative emotions and lead to supportive behavior and ethical consumption intention

Compulsive and Impulsive Shoppers: Hoarding of Fast Fashion Products

Although anecdotal evidence suggests that fast fashion is made of low quality materials, little research has been done to understand how perceptions of fast fashion quality affects consumer purchasing frequency. Furthermore, studies have identified that compulsive and impulsive shopping is tied to hoarding behavior including difficulty discarding and value oriented hoarding. The connection between fast fashion purchasing frequency and compulsive, impulsive and hoarding behaviors has not been, a gap in the research which this study sought to fill. To understand impulsive and compulsive consumers\u27 fast fashion purchasing frequency and the effects that the apparel quality had on hoarding behaviors, an online survey was conducted with a random nationwide sample of 500 women ages 18-59. This homogenous sample was evenly distributed across ages and the resulting racial ethnicities closely represented US population. Results are discussed and implications are provided

Reaction fronts, permeability and fluid pressure development during dehydration reactions

NE/J008303/1, NERC, Natural Environment Research Counci

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

STAT6 (signal transducer and activator of transcription 6) is a transcription factor that plays a central role in the pathophysiology of allergic inflammation. We have identified 16 patients from 10 families spanning three continents with a profound phenotype of early-life onset allergic immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia with esosinophilic gastrointestinal disease, asthma, elevated serum IgE, IgE-mediated food allergies, and anaphylaxis. The cases were either sporadic (seven kindreds) or followed an autosomal dominant inheritance pattern (three kindreds). All patients carried monoallelic rare variants in STAT6 and functional studies established their gain-of-function (GOF) phenotype with sustained STAT6 phosphorylation, increased STAT6 target gene expression, and TH2 skewing. Precision treatment with the anti-IL-4Rα antibody, dupilumab, was highly effective improving both clinical manifestations and immunological biomarkers. This study identifies heterozygous GOF variants in STAT6 as a novel autosomal dominant allergic disorder. We anticipate that our discovery of multiple kindreds with germline STAT6 GOF variants will facilitate the recognition of more affected individuals and the full definition of this new primary atopic disorder

Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.

BACKGROUND: Staphylococcus aureus bacteraemia is a common cause of severe community-acquired and hospital-acquired infection worldwide. We tested the hypothesis that adjunctive rifampicin would reduce bacteriologically confirmed treatment failure or disease recurrence, or death, by enhancing early S aureus killing, sterilising infected foci and blood faster, and reducing risks of dissemination and metastatic infection. METHODS: In this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years) with S aureus bacteraemia who had received ≤96 h of active antibiotic therapy were recruited from 29 UK hospitals. Patients were randomly assigned (1:1) via a computer-generated sequential randomisation list to receive 2 weeks of adjunctive rifampicin (600 mg or 900 mg per day according to weight, oral or intravenous) versus identical placebo, together with standard antibiotic therapy. Randomisation was stratified by centre. Patients, investigators, and those caring for the patients were masked to group allocation. The primary outcome was time to bacteriologically confirmed treatment failure or disease recurrence, or death (all-cause), from randomisation to 12 weeks, adjudicated by an independent review committee masked to the treatment. Analysis was intention to treat. This trial was registered, number ISRCTN37666216, and is closed to new participants. FINDINGS: Between Dec 10, 2012, and Oct 25, 2016, 758 eligible participants were randomly assigned: 370 to rifampicin and 388 to placebo. 485 (64%) participants had community-acquired S aureus infections, and 132 (17%) had nosocomial S aureus infections. 47 (6%) had meticillin-resistant infections. 301 (40%) participants had an initial deep infection focus. Standard antibiotics were given for 29 (IQR 18-45) days; 619 (82%) participants received flucloxacillin. By week 12, 62 (17%) of participants who received rifampicin versus 71 (18%) who received placebo experienced treatment failure or disease recurrence, or died (absolute risk difference -1·4%, 95% CI -7·0 to 4·3; hazard ratio 0·96, 0·68-1·35, p=0·81). From randomisation to 12 weeks, no evidence of differences in serious (p=0·17) or grade 3-4 (p=0·36) adverse events were observed; however, 63 (17%) participants in the rifampicin group versus 39 (10%) in the placebo group had antibiotic or trial drug-modifying adverse events (p=0·004), and 24 (6%) versus six (2%) had drug interactions (p=0·0005). INTERPRETATION: Adjunctive rifampicin provided no overall benefit over standard antibiotic therapy in adults with S aureus bacteraemia. FUNDING: UK National Institute for Health Research Health Technology Assessment

Light-based technologies for management of COVID-19 pandemic crisis.

The global dissemination of the novel coronavirus disease (COVID-19) has accelerated the need for the implementation of effective antimicrobial strategies to target the causative agent SARS-CoV-2. Light-based technologies have a demonstrable broad range of activity over standard chemotherapeutic antimicrobials and conventional disinfectants, negligible emergence of resistance, and the capability to modulate the host immune response. This perspective article identifies the benefits, challenges, and pitfalls of repurposing light-based strategies to combat the emergence of COVID-19 pandemic

Does This Bag Make Me Look Good? The Impact of Post-Consumption Emotions on Re-Purchase Intention of Counterfeit Luxury Products

Individuals often consume products as a means of expressing themselves to those they interact with. Previous studies demonstrate that consumers use branded products to enhance their self-identity, highlight individuality, and increase social approval. (Geiger-Oneto et al., 2013), which is evident particularly in luxury consumption behavior (Vigneron & Johnson, 1999). As previous studies focused on examining predictors of luxury purchase intention (e.g., Bian & Forsythe, 2012), this study is interested in how consumers' post-purchase emotions influence their intention of re-purchasing a luxury counterfeit. In addition, this study proposes that the effects of goal incongruence on aroused emotions are contingent upon the agent who causes the emotions (i.e., self, others) This study adopts emotion theory and appraisal theories as conceptual framework to examine a study phenomenon of interest. Our findings demonstrated that different post-consumption emotions are generated differently depending on the causation agent. Results, discussion and implications are presented.</p

Compulsive and Impulsive Shoppers: Hoarding of Fast Fashion Products

Although anecdotal evidence suggests that fast fashion is made of low quality materials, little research has been done to understand how perceptions of fast fashion quality affects consumer purchasing frequency. Furthermore, studies have identified that compulsive and impulsive shopping is tied to hoarding behavior including difficulty discarding and value oriented hoarding. The connection between fast fashion purchasing frequency and compulsive, impulsive and hoarding behaviors has not been, a gap in the research which this study sought to fill. To understand impulsive and compulsive consumers' fast fashion purchasing frequency and the effects that the apparel quality had on hoarding behaviors, an online survey was conducted with a random nationwide sample of 500 women ages 18-59. This homogenous sample was evenly distributed across ages and the resulting racial ethnicities closely represented US population. Results are discussed and implications are provided.</p

Can Fear Stop Animal Cruelty in Fashion Industry? The Effect of Negative Arousal in a Nonprofit Organization’s Social Media Campaigns

This study focuses on the issue of animal cruelty which is a relatively under-investigated topic in the fashion industry and aims to investigate how different levels of animal cruelty depicted in nonprofit organizations’ ethical consumption campaigns translate into viewers’ negative emotions and lead to supportive behavior and ethical consumption intention.</p