Melk kan nog gezonder

Melk biedt niet alleen bescherming aan zuigelingen en pasgeboren zoogdieren. Ook gespeende dieren en volwassenen profiteren van de gezonde inhoudsstoffen in melk. Dankzij nieuwe technieken heeft ASG zicht op voermethoden die het gehalte aan gezondheidsbevorderende stoffen in melk verhoge

NMR Detection of Temperature-Dependent Magnetic Inhomogeneities in URu2Si2

We present 29Si-NMR relaxation and spectral data in URu2Si2. Our echo-decay experiments detect slowly fluctuating magnetic field gradients. In addition, we find that the echo-decay shape (time dependence) varies with temperature T and its rate behaves critically near the Neel temperature TN, indicating a correlation between the gradient fluctuations and the transition to small-moment order. T-dependent broadening contributions become visible below 100 Kelvin and saturate somewhat above TN, remaining saturated at lower temperatures. Together, the line width and shift suggest partial lattice distortions below TN. We propose an intrinsic minority phase below $T_{\rm N}$ and compare our results with one of the current theoretical models.Comment: 2 pages RevTeX, 1 figure, SCES 99-Japan, to appear in Physica

Lifetimes of electrons in the Shockley surface state band of Ag(111)

We present a theoretical many-body analysis of the electron-electron (e-e) inelastic damping rate $\Gamma$ of electron-like excitations in the Shockley surface state band of Ag(111). It takes into account ab-initio band structures for both bulk and surface states. $\Gamma$ is found to increase more rapidly as a function of surface state energy E than previously reported, thus leading to an improved agreement with experimental data

Voedingsvezels als vallen voor schadelijke darmbacteriën

Ziekteverwekkende bacteriën binden zich in de darm aan specifieke celreceptoren. Door voedingsvezels aan te bieden die overeenkomsten vertonen met deze receptoren, kunnen bacteriën worden misleid. Zij binden zich dan ook aan de voedingsvezels en niet per se aan de darmcellen, en worden vervolgens via de feces uitgescheiden en zo in aantal verminder

Knoflook remt App

De Animal Sciences Group van Wageningen UR heeft in opdracht van biologische varkenshouders onderzocht of het mogelijk is om in plaats van antibiotica, knoflook te gebruiken voor de bestrijding van longontsteking door de bacterie Actinobacillus pleuropneumoniae (App). Uit de resultaten blijkt dat Allyl Methyl Sulfi de (AMS), een omzettingsproduct van knoflook, de groei van App remt

Double-Scaling Limit of Heterotic Bundles and Dynamical Deformation in CFT

We consider heterotic string theory on Eguchi-Hanson space, as a local model of a resolved A_1 singularity in a six-dimensional flux compactification, with an Abelian gauge bundle turned on and non-zero torsion. We show that in a suitable double scaling limit, that isolates the physics near the non-vanishing two-cycle, a worldsheet conformal field theory description can be found. It contains a heterotic coset whose target space is conformal to Eguchi-Hanson. Starting from the blow-down limit of the singularity, it can be viewed as a dynamical deformation of the near-horizon fivebrane background. We analyze in detail the spectrum of the theory in particular examples, as well as the important role of worldsheet non-perturbative effects.Comment: 45 pages, no figures; ver2: typos corrected, references added, an extra tadpole-free model covere

Community health survey of Oukasie, 1987

A series of surveys were conducted at the request of the community of Oukasie to determine certain public health information in the township, a peri-urban black community. This article describes two of these surveys. The first, a census and partial demographic survey, showed that the total black population was around 6300 with a mean household occupancy of 4,1. Some of the estimated vital statistics calculated were an infant mortality rate of 36,6/1 000, a crude birth rate of 28,0/1 000, a crude death rate of 6,5/1000, and a general fertility rate of 99,3/1 000. The second survey into the nutritional and immunisation status of children aged under 5 years showed that 20% of children were underweight and nearly half were incompletely immunised at 1 year of age. These studies, involving local community and student volunteers, were rapidly and inexpensively done and provide basic public health Information

Restructuring of colloidal aggregates in shear flow: Coupling interparticle contact models with Stokesian dynamics

A method to couple interparticle contact models with Stokesian dynamics (SD) is introduced to simulate colloidal aggregates under flow conditions. The contact model mimics both the elastic and plastic behavior of the cohesive connections between particles within clusters. Owing to this, clusters can maintain their structures under low stress while restructuring or even breakage may occur under sufficiently high stress conditions. SD is an efficient method to deal with the long-ranged and many-body nature of hydrodynamic interactions for low Reynolds number flows. By using such a coupled model, the restructuring of colloidal aggregates under stepwise increasing shear flows was studied. Irreversible compaction occurs due to the increase of hydrodynamic stress on clusters. Results show that the greater part of the fractal clusters are compacted to rod-shaped packed structures, while the others show isotropic compaction.Comment: A simulation movie be found at http://www-levich.engr.ccny.cuny.edu/~seto/sites/colloidal_aggregates_shearflow.htm

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration

Chemotherapy is one of the pillars of anti-cancer therapy. Although chemotherapeutics cause regression of the primary tumor, many chemotherapeutics are often shown to induce or accelerate metastasis formation. Moreover, metastatic tumors are largely resistant against chemotherapy. As more than 90% of cancer patients die due to metastases and not due to primary tumor formation, novel drugs are needed to overcome these shortcomings. In this study, we identified the anticancer phytochemical Rocaglamide (Roc-A) to be an inhibitor of cancer cell migration, a crucial event in metastasis formation. We show that Roc-A inhibits cellular migration and invasion independently of its anti-proliferative and cytotoxic effects in different types of human cancer cells. Mechanistically, Roc-A treatment induces F-actin-based morphological changes in membrane protrusions. Further investigation of the molecular mechanisms revealed that Roc-A inhibits the activities of the small GTPases RhoA, Rac1 and Cdc42, the master regulators of cellular migration. Taken together, our results provide evidence that Roc-A may be a lead candidate for a new class of anticancer drugs that inhibit metastasis formation