117 research outputs found

    Differential-geometry scaling method for electromagnetic field and its applications to coaxial waveguide junctions

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    It is well-known that in mechanics and fluid dynamics one can transform or scale one problem and its solution to create a whole class of equivalent problems and their solutions[1]. Different problems and their solution behaviors of one equivalent class may look very different, but among them there are properties they share. The essence of such a scaling is to get appropriate dimensionless parameters that are common to them all

    A Switched Oscillator as an Antenna for High Power THz Generation

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    This paper presents an approach to high power THz generation that uses a Switched Oscillator (SwO) as a photoconductively-switched antenna. A simplified model is used to demonstrate the SwO as an effective THz radiator. Numerical simulations are used to optimize various parameters of interest with the primary objective of maximizing the radiated energy and minimizing losses. The radiation Q and resonant frequency are obtained as function of each parameter

    Perturbative Duality in the Resonance Spin Structure Functions

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    We investigate the relations between the spin structure functions in the scaling and resonance regions. We examine the possible duality between the two, and draw inferences for the behavior of the asymmetry A_1 at large x. Finally, we point out the importance of additional polarized structure function data in the resonance region in terms of testing the hysteresis of perturbative physics.Comment: 4 pages, revtex, no figure

    Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes

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    While numerous studies have implicated copy number variants (CNVs) in a range of neurological phenotypes, the impact relative to disease severity has been difficult to ascertain due to small sample sizes, lack of phenotypic details, and heterogeneity in platforms used for discovery. Using a customized microarray enriched for genomic hotspots, we assayed for large CNVs among 1,227 individuals with various neurological deficits including dyslexia (376), sporadic autism (350), and intellectual disability (ID) (501), as well as 337 controls. We show that the frequency of large CNVs (>1 Mbp) is significantly greater for ID–associated phenotypes compared to autism (p = 9.58×10−11, odds ratio = 4.59), dyslexia (p = 3.81×10−18, odds ratio = 14.45), or controls (p = 2.75×10−17, odds ratio = 13.71). There is a striking difference in the frequency of rare CNVs (>50 kbp) in autism (10%, p = 2.4×10−6, odds ratio = 6) or ID (16%, p = 3.55×10−12, odds ratio = 10) compared to dyslexia (2%) with essentially no difference in large CNV burden among dyslexia patients compared to controls. Rare CNVs were more likely to arise de novo (64%) in ID when compared to autism (40%) or dyslexia (0%). We observed a significantly increased large CNV burden in individuals with ID and multiple congenital anomalies (MCA) compared to ID alone (p = 0.001, odds ratio = 2.54). Our data suggest that large CNV burden positively correlates with the severity of childhood disability: ID with MCA being most severely affected and dyslexics being indistinguishable from controls. When autism without ID was considered separately, the increase in CNV burden was modest compared to controls (p = 0.07, odds ratio = 2.33)

    The James Webb Space Telescope Mission

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    Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least 4m4m. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the 6.5m6.5m James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

    The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation

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    Combined Electric and Magnetic Dipoles for Mesoband Radiation”, Sensor and Simulation Note 523,

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    Abstract This paper continues the discussion of the design of an antenna with collinear electric-and magnetic-dipole moments out of phase by approximately / 2 (90 ) π . Using a high-Q approximation, a switched oscillator is matched to the antenna for radiating an oscillatory pulse. ` This work was sponsored in part by the Air Force Office of Scientific Research
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