592 research outputs found
Alteration and recovery of arm usage in daily activities after rotator cuff surgery.
BACKGROUND: The objective measurement of dominant/nondominant arm use proportion in daily life may provide relevant information on healthy and pathologic arm behavior. This prospective case-control study explored the potential of such measurements as indicators of upper limb functional recovery after rotator cuff surgery.
METHODS: Data on dominant/nondominant arm usage were acquired with body-worn sensors for 7 hours. The postsurgical arm usage of 21 patients was collected at 3, 6, and 12Â months after rotator cuff surgery in the sitting, walking, and standing postures and compared with a reference established with 41 healthy subjects. The results were calculated for the dominant and nondominant surgical side subgroups at all stages. The correlations with clinical scores were calculated.
RESULTS: Healthy right-handed and left-handed dominant arm usage was 60.2% (±6.3%) and 53.4% (±6.6%), respectively. Differences in use of the dominant side were significant between the right- and left-handed subgroups for sitting (P = .014) and standing (P = .009) but not for walking (P = .328). The patient group showed a significant underuse of 10.7% (±8.9%) at 3 months after surgery (P < .001). The patients recovered normal arm usage within 12 months, regardless of surgical side. The arm underuse measurement was weakly related to function and pain scores.
CONCLUSION: This study provided new information on arm recovery after rotator cuff surgery using an innovative measurement method. It highlighted that objective arm underuse measurement is a valuable indicator of upper limb postsurgical outcome that captures a complementary feature to clinical scores
Characterization of RNA from Noninfectious Virions Produced by Sarcoma Positive-Leukemia Negative Transformed 3T3 Cells
Geo-neutrinos: A systematic approach to uncertainties and correlations
Geo-neutrinos emitted by heat-producing elements (U, Th and K) represent a
unique probe of the Earth interior. The characterization of their fluxes is
subject, however, to rather large and highly correlated uncertainties. The
geochemical covariance of the U, Th and K abundances in various Earth
reservoirs induces positive correlations among the associated geo-neutrino
fluxes, and between these and the radiogenic heat. Mass-balance constraints in
the Bulk Silicate Earth (BSE) tend instead to anti-correlate the radiogenic
element abundances in complementary reservoirs. Experimental geo-neutrino
observables may be further (anti)correlated by instrumental effects. In this
context, we propose a systematic approach to covariance matrices, based on the
fact that all the relevant geo-neutrino observables and constraints can be
expressed as linear functions of the U, Th and K abundances in the Earth's
reservoirs (with relatively well-known coefficients). We briefly discuss here
the construction of a tentative "geo-neutrino source model" (GNSM) for the U,
Th, and K abundances in the main Earth reservoirs, based on selected
geophysical and geochemical data and models (when available), on plausible
hypotheses (when possible), and admittedly on arbitrary assumptions (when
unavoidable). We use then the GNSM to make predictions about several
experiments ("forward approach"), and to show how future data can constrain - a
posteriori - the error matrix of the model itself ("backward approach"). The
method may provide a useful statistical framework for evaluating the impact and
the global consistency of prospective geo-neutrino measurements and Earth
models.Comment: 17 pages, including 4 figures. To appear on "Earth, Moon, and
Planets," Special Issue on "Neutrino Geophysics," Proceedings of Neutrino
Science 2005 (Honolulu, Hawaii, Dec. 2005
Density and Pâwave velocity structure beneath the ParanĂĄ Magmatic Province: Refertilization of an ancient lithospheric mantle
We estimate density and Pâwave velocity perturbations in the mantle beneath the southeastern South America plate from geoid anomalies and Pâwave traveltime residuals to constrain the structure of the lithosphere underneath the ParanĂĄ Magmatic Province (PMP) and conterminous geological provinces. Our analysis shows a consistent correlation between density and velocity anomalies. The Pâwave speed and density are 1% and 15 kg/m3 lower, respectively, in the upper mantle under the Late Cretaceous to Cenozoic alkaline provinces, except beneath the GoiĂĄs Alkaline Province (GAP), where density (+20 kg/m3) and velocity (+0.5%) are relatively high. Underneath the PMP, the density is higher by about 50 kg/m3 in the north and 25 kg/m3 in the south, to a depth of 250âââ300 km. These values correlate with highâvelocity perturbations of +0.5% and +0.3%, respectively. Profiles of density perturbation versus depth in the upper mantle are different for the PMP and the adjacent Archean SĂŁo Francisco (SFC) and Amazonian (AC) cratons. The Paleoproterozoic PMP basement has a highâdensity root. The density is relatively low in the SFC and AC lithospheres. A reduction of density is a typical characteristic of chemically depleted Archean cratons. A more fertile Proterozoic and Phanerozoic subcontinental lithospheric mantle has a higher density, as deduced from density estimates of mantle xenoliths of different ages and composition. In conjunction with ReâOs isotopic studies of the PMP basalts, chemical and isotopic analyses of peridodite xenoliths from the GAP in the northern PMP, and electromagnetic induction experiments of the PMP lithosphere, our density and Pâwave speed models suggest that the densification of the PMP lithosphere and flood basalt generation are related to mantle refertilization. Metasomatic refertilization resulted from the introduction of asthenospheric components from the mantle wedge above Proterozoic subduction zones, which surrounded the ParanĂĄ lithosphere. The highâdensity PMP lithosphere is presently gravitationally unstable and prone to delamination.Key Points:Density and Pâwave velocity in the lithospheric mantle beneath the ParanĂĄ Magmatic Province are highHigh density precludes a depleted cratonic lithosphere and indicates refertilized lithospheric mantleBasalt magmatism suggests refertilized mantle with asthenospheric components from mantle wedgePeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134193/1/ggge21079-sup-0003-2016GC006369-fs02.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134193/2/ggge21079-sup-0004-2016GC006369-fs03.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134193/3/ggge21079-sup-0002-2016GC006369-fs01.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134193/4/ggge21079_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134193/5/ggge21079.pd
U and Th content in the Central Apennines continental crust: a contribution to the determination of the geo-neutrinos flux at LNGS
The regional contribution to the geo-neutrino signal at Gran Sasso National
Laboratory (LNGS) was determined based on a detailed geological, geochemical
and geophysical study of the region. U and Th abundances of more than 50
samples representative of the main lithotypes belonging to the Mesozoic and
Cenozoic sedimentary cover were analyzed. Sedimentary rocks were grouped into
four main "Reservoirs" based on similar paleogeographic conditions and
mineralogy. Basement rocks do not outcrop in the area. Thus U and Th in the
Upper and Lower Crust of Valsugana and Ivrea-Verbano areas were analyzed. Based
on geological and geophysical properties, relative abundances of the various
reservoirs were calculated and used to obtain the weighted U and Th abundances
for each of the three geological layers (Sedimentary Cover, Upper and Lower
Crust). Using the available seismic profile as well as the stratigraphic
records from a number of exploration wells, a 3D modelling was developed over
an area of 2^{\circ}x2^{\circ} down to the Moho depth, for a total volume of
about 1.2x10^6 km^3. This model allowed us to determine the volume of the
various geological layers and eventually integrate the Th and U contents of the
whole crust beneath LNGS. On this base the local contribution to the
geo-neutrino flux (S) was calculated and added to the contribution given by the
rest of the world, yielding a Refined Reference Model prediction for the
geo-neutrino signal in the Borexino detector at LNGS: S(U) = (28.7 \pm 3.9) TNU
and S(Th) = (7.5 \pm 1.0) TNU. An excess over the total flux of about 4 TNU was
previously obtained by Mantovani et al. (2004) who calculated, based on general
worldwide assumptions, a signal of 40.5 TNU. The considerable thickness of the
sedimentary rocks, almost predominantly represented by U- and Th- poor
carbonatic rocks in the area near LNGS, is responsible for this difference.Comment: 45 pages, 5 figures, 12 tables; accepted for publication in GC
Unravelling the reasons for disproportion in the ratio of AOB and NOB in aerobic granular sludge
In this study, we analysed the nitrifying microbial community (ammonium-oxidizing bacteria (AOB) and nitrite-oxidizing bacteria (NOB)) within three different aerobic granular sludge treatment systems as well as within one flocculent sludge system. Granular samples were taken from one pilot plant run on municipal wastewater as well as from two lab-scale reactors. Fluorescent in situ hybridization (FISH) and quantitative PCR (qPCR) showed that Nitrobacter was the dominant NOB in acetate-fed aerobic granules. In the conventional system, both Nitrospira and Nitrobacter were present in similar amounts. Remarkably, the NOB/AOB ratio in aerobic granular sludge was elevated but not in the conventional treatment plant suggesting that the growth of Nitrobacter within aerobic granular sludge, in particular, was partly uncoupled from the lithotrophic nitrite supply from AOB. This was supported by activity measurements which showed an approximately threefold higher nitrite oxidizing capacity than ammonium oxidizing capacity. Based on these findings, two hypotheses were considered: either Nitrobacter grew mixotrophically by acetate-dependent dissimilatory nitrate reduction (ping-pong effect) or a nitrite oxidation/nitrate reduction loop (nitrite loop) occurred in which denitrifiers reduced nitrate to nitrite supplying additional nitrite for the NOB apart from the AOB
Temperature-induced changes in treatment efficiency and microbial structure of aerobic granules treating landfill leachate
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