The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes

© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early outcomes of AVF formed with the sampled vein. Methods Ethical approval was obtained for all aspects of this study. During AVF formation a circumferential segment of the target vein was sampled. Mechanical stress testing of the venous segments was undertaken using a dynamic mechanical analyzer, with progressive stress loading at 2 N/min to a maximum of 10 N or until sample disruption. Stress-strain curves were obtained for vein samples and Young's modulus (YM) calculated. Duplex assessment of the fistulae was undertaken at 30 days. Results Thirty patients consented to participate with 29 samples obtained for analysis. Statistical comparison of YM demonstrated no relationship with common cardiovascular risk factors or dialysis status. Subject age greater than 65 was the only patient factor which showed a significant difference in YM (P = 0.05). Furthermore, a negative correlation was confirmed between age and YM (Pearson's r = -0.465, P < 0.05). Nine of the 29 subjects suffered an early AVF failure. Mann-Whitney U testing for differences in distribution reported that YM was significantly higher in those fistulas which failed (P < 0.005). Conclusions Reduced venous compliance appears to result in higher failure rates of AVFs. With the advancement of clinical tools such as speckle tracing ultrasound identification of vessel compliance in vivo may produce valuable additional information for clinicians planning AVF surgery

Efficient Resource Matching in Heterogeneous Grid Using Resource Vector

In this paper, a method for efficient scheduling to obtain optimum job throughput in a distributed campus grid environment is presented; Traditional job schedulers determine job scheduling using user and job resource attributes. User attributes are related to current usage, historical usage, user priority and project access. Job resource attributes mainly comprise of soft requirements (compilers, libraries) and hard requirements like memory, storage and interconnect. A job scheduler dispatches jobs to a resource if a job's hard and soft requirements are met by a resource. In current scenario during execution of a job, if a resource becomes unavailable, schedulers are presented with limited options, namely re-queuing job or migrating job to a different resource. Both options are expensive in terms of data and compute time. These situations can be avoided, if the often ignored factor, availability time of a resource in a grid environment is considered. We propose resource rank approach, in which jobs are dispatched to a resource which has the highest rank among all resources that match the job's requirement. The results show that our approach can increase throughput of many serial / monolithic jobs.Comment: 10 page

Line narrowing of AgGaSe2 optical parametric oscillator by injection seeding

Solid-state lasers are developed for atmospheric applications. Optical parametric oscillators (OPO) are being investigated as sources of tunable radiation in the 2.5-12 micron range where development of conventional lasers is subject to numerous difficulties. Parametric oscillation is a nonlinear optical technique for converting laser output to longer wavelengths. Incident photons, typically from a pulsed pump laser, are converted into two photons of longer wavelength, while satisfying energy conservation. The particular split of energy is determined by momentum conservation; the wavelength of interest is usually selected by angle orientation of the nonlinear material with respect to the direction of propagation of the pump beam. An OPO based on AgGaSe2 was considered

Synthesis and applications of indenopyrazine based polymers for use in organic electronics

The first part of this thesis is devoted to the synthesis, purification and application of a series of indenopyrazine based polymers for their use in optoelectronic devices. The work focuses on the effect of alternating chain length on the degree of polymerisation, optical and charge carrier properties The next section studies the copolymerisation of indenopyrazine with dithiophene benzothiadiazole acceptor units and the effect substituents have on the planarity of the polymer backbone and the delocalisation of molecular orbitals and solar cell performance. The final part of this thesis investigates indenopyrazine based polymers as charge carrier materials in p-type transistors and probes the effect p-dopants have on the energy levels, charge carrier mobility and optical properties. The second part is the synthesis of the novel alkylidene-indenopyrazine monomer and probes the introduction of enforced planarity and finally the synthesis towards the novel the semiconductor indenopyrazinedithiophene.Open Acces

Parallel access alignment network with barrel switch implementation for d-ordered vector elements

An alignment network between N parallel data input ports and N parallel data outputs includes a first and a second barrel switch. The first barrel switch fed by the N parallel input ports shifts the N outputs thereof and in turn feeds the N-1 input data paths of the second barrel switch according to the relationship X=k.sup.y modulo N wherein x represents the output data path ordering of the first barrel switch, y represents the input data path ordering of the second barrel switch, and k equals a primitive root of the number N. The zero (0) ordered output data path of the first barrel switch is fed directly to the zero ordered output port. The N-1 output data paths of the second barrel switch are connected to the N output ports in the reverse ordering of the connections between the output data paths of the first barrel switch and the input data paths of the second barrel switch. The second switch is controlled by a value m, which in the preferred embodiment is produced at the output of a ROM addressed by the value d wherein d represents the incremental spacing or distance between data elements to be accessed from the N input ports, and m is generated therefrom according to the relationship d=k.sup.m modulo N

NASA and the challenge of ISDN: The role of satellites in an ISDN world

To understand what role satellites may play in Integrated Services Digital Network (ISDN), it is necessary to understand the concept of ISDN, including key organizations involved, the current status of key standards recommendations, and domestic and international progress implementation of ISDN. Each of these areas are explained. A summary of the technical performance criteria for ISDN, current standards for satellites in ISDN, key players in the ISDN environment, and what steps can be taken to encourage application of satellites in ISDN are also covered