11 research outputs found

    Panel. Enseñar formación ética y ciudadana en la escuela secundaria de hoy. Parte I

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    Fil: Ferreyra, Horacio Ademar. Universidad Católica de Córdoba. Facultad de Educación; ArgentinaFil: Di Francesco, Adriana Carlota. Universidad Católica de Córdoba. Facultad de Educación; Argentin

    Preguntas, respuestas y propuestas para su enseñanza.

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    El estudio, la reflexión y el debate en torno al Holocausto nos permiten no sólo ejercer la memoria sobre un hecho clave de la historia y de profundas consecuencias en la cultura humana, sino abrir una serie de interrogantes acerca de la comprensión y el respeto de la otredad en nuestras propias comunidades, la defensa y el respeto de la diversidad, capitales para la construcción de ciudadanía. Es en este sentido que consideramos que su estudio, en tanto acontecimiento histórico, puede ser un "puente" para interpelarnos sobre nuestra propia exigencia: cómo participar de una vida ciudadana activa y responsable; cómo no ser indiferentes ante el dolor de los demás; cómo exigir que las sociedades y los gobiernos respeten los derechos humanos universales.Esta publicación constituye un material de apoyo para pensar, debatir y problematizar algunos de los temas relevantes en relación al Holocausto y su enseñanza. Continúa una línea de trabajo comenzada con las publicaciones: LA SHOÁ EN LA PANTALLA (2007) y MEMORIAS EN FRAGMENTOS (2009). En esta oportunidad, el material está organizado en una serie de preguntas y respuestas que se detienen, por un lado, en los hechos principales vinculados al acontecimiento y, por otro, repasan los problemas teóricos e históricos que se fueron desarrollando desde aquel tiempo hasta el presente. Para complementar la propuesta, el libro incluye una breve selección de textos e imágenes. Además, se incluyen propuestas con posibles abordajes para trabajar en el aula a partir de cada una de las preguntas

    Establishing a core outcome set for peritoneal dialysis : report of the SONG-PD (standardized outcomes in nephrology-peritoneal dialysis) consensus workshop

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    Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians. The Standardized Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD) initiative aims to establish a core outcome set for trials in PD based on the shared priorities of all stakeholders. We convened an international SONG-PD stakeholder consensus workshop in May 2018 in Vancouver, Canada. Nineteen patients/caregivers and 51 health professionals attended. Participants discussed core outcome domains and implementation in trials in PD. Four themes relating to the formation of core outcome domains were identified: life participation as a main goal of PD, impact of fatigue, empowerment for preparation and planning, and separation of contributing factors from core factors. Considerations for implementation were identified: standardizing patient-reported outcomes, requiring a validated and feasible measure, simplicity of binary outcomes, responsiveness to interventions, and using positive terminology. All stakeholders supported inclusion of PD-related infection, cardiovascular disease, mortality, technique survival, and life participation as the core outcome domains for PD

    Plasma Levels of Middle Molecules to Estimate Residual Kidney Function in Haemodialysis without Urine Collection

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    © 2015 Vilar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.BACKGROUND: Residual Kidney Function (RKF) is associated with survival benefits in haemodialysis (HD) but is difficult to measure without urine collection. Middle molecules such as Cystatin C and β2-microglobulin accumulate in renal disease and plasma levels have been used to estimate kidney function early in this condition. We investigated their use to estimate RKF in patients on HD. DESIGN: Cystatin C, β2-microglobulin, urea and creatinine levels were studied in patients on incremental high-flux HD or hemodiafiltration(HDF). Over sequential HD sessions, blood was sampled pre- and post-session 1 and pre-session 2, for estimation of these parameters. Urine was collected during the whole interdialytic interval, for estimation of residual GFR (GFRResidual = mean of urea and creatinine clearance). The relationships of plasma Cystatin C and β2-microglobulin levels to GFRResidual and urea clearance were determined. RESULTS: Of the 341 patients studied, 64% had urine output>100 ml/day, 32.6% were on high-flux HD and 67.4% on HDF. Parameters most closely correlated with GFRResidual were 1/β2-micoglobulin (r2 0.67) and 1/Cystatin C (r2 0.50). Both these relationships were weaker at low GFRResidual. The best regression model for GFRResidual, explaining 67% of the variation, was: GFRResidual = 160.3 · (1/β2m) - 4.2. Where β2m is the pre-dialysis β2 microglobulin concentration (mg/L). This model was validated in a separate cohort of 50 patients using Bland-Altman analysis. Areas under the curve in Receiver Operating Characteristic analysis aimed at identifying subjects with urea clearance≥2 ml/min/1.73 m2 was 0.91 for β2-microglobulin and 0.86 for Cystatin C. A plasma β2-microglobulin cut-off of ≤19.2 mg/L allowed identification of patients with urea clearance ≥2 ml/min/1.73 m2 with 90% specificity and 65% sensitivity. CONCLUSION: Plasma pre-dialysis β2-microglobulin levels can provide estimates of RKF which may have clinical utility and appear superior to cystatin C. Use of cut-off levels to identify patients with RKF may provide a simple way to individualise dialysis dose based on RKF.Peer reviewe
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