46 research outputs found

    Scalable many-core algorithms for tridiagonal solvers

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    We present a novel distributed memory Tridiagonal solver library, targeting large-scale systems based on modern multi-core and many-core processor architectures. The library uses methods based on both approximate and exact algorithms. Performance comparisons with the state-of-the-art, using both a large Cray EX system and a GPU cluster show the algorithmic trade-offs required at increasing machine scale to achieve good performance, particularly considering the advent of exascale systems

    Does timing of decisions in a mixed duopoly matter?

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    We determine the endogenous order of moves in a mixed pricesetting duopoly. In contrast to the existing literature on mixed oligopolies we establish the payo equivalence of the games with an exogenously given order of moves if the most plausible equilibrium is realized in the market. Hence, in this case it does not matter whether one becomes a leader or a follower. We also establish that replacing a private firm by a public firm in the standard Bertrand-Edgeworth game with capacity constraints increases social welfare and that a pure-strategy equilibrium always exists

    Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium

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    Intra-synovial tendon injuries display poor healing, which often results in reduced functionality and pain. A lack of effective therapeutic options has led to experimental approaches to augment natural tendon repair with autologous mesenchymal stem cells (MSCs) although the effects of the intra-synovial environment on the distribution, engraftment and functionality of implanted MSCs is not known. This study utilised a novel sheep model which, although in an anatomically different location, more accurately mimics the mechanical and synovial environment of the human rotator cuff, to determine the effects of intra-synovial implantation of MSCs

    The GOGREEN survey: The environmental dependence of the star-forming galaxy main sequence at 1.0<z<1.51.0<z<1.5

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    We present results on the environmental dependence of the star-forming galaxy main sequence in 11 galaxy cluster fields at 1.0<z<1.51.0 < z < 1.5 from the Gemini Observations of Galaxies in Rich Early Environments Survey (GOGREEN) survey. We use a homogeneously selected sample of field and cluster galaxies whose membership is derived from dynamical analysis. Using [OII]-derived star formation rates (SFRs), we find that cluster galaxies have suppressed SFRs at fixed stellar mass in comparison to their field counterparts by a factor of 1.4 ±\pm 0.1 (3.3σ\sim3.3\sigma) across the stellar mass range: 9.0<log(M/M)<11.29.0 < \log(M_{*} /M_{\odot}) < 11.2. We also find that this modest suppression in the cluster galaxy star-forming main sequence is mass and redshift dependent: the difference between cluster and field increases towards lower stellar masses and lower redshift. When comparing the distribution of cluster and field galaxy SFRs to the star-forming main sequence, we find an overall shift towards lower SFRs in the cluster population, and note the absence of a tail of high SFR galaxies as seen in the field. Given this observed suppression in the cluster galaxy star-forming main sequence, we explore the implications for several scenarios such as formation time differences between cluster and field galaxies, and environmentally-induced star formation quenching and associated timescales

    GOGREEN: a critical assessment of environmental trends in cosmological hydrodynamical simulations at z ~ 1

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    Recent observations have shown that the environmental quenching of galaxies at z ∼ 1 is qualitatively different to that in the local Universe. However, the physical origin of these differences has not yet been elucidated. In addition, while low-redshift comparisons between observed environmental trends and the predictions of cosmological hydrodynamical simulations are now routine, there have been relatively few comparisons at higher redshifts to date. Here we confront three state-of-the-art suites of simulations (BAHAMAS+MACSIS, EAGLE+Hydrangea, IllustrisTNG) with state-of-the-art observations of the field and cluster environments from the COSMOS/UltraVISTA and GOGREEN surveys, respectively, at z ∼ 1 to assess the realism of the simulations and gain insight into the evolution of environmental quenching. We show that while the simulations generally reproduce the stellar content and the stellar mass functions of quiescent and star-forming galaxies in the field, all the simulations struggle to capture the observed quenching of satellites in the cluster environment, in that they are overly efficient at quenching low-mass satellites. Furthermore, two of the suites do not sufficiently quench the highest mass galaxies in clusters, perhaps a result of insufficient feedback from AGN. The origin of the discrepancy at low stellar masses (⁠M∗≲1010 M⊙), which is present in all the simulations in spite of large differences in resolution, feedback implementations, and hydrodynamical solvers, is unclear. The next generation of simulations, which will push to significantly higher resolution and also include explicit modelling of the cold interstellar medium, may help us to shed light on the low-mass tension

    Building a Digital Wind Farm

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    2016 WSES guidelines on acute calculous cholecystitis

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