882 research outputs found
Major Modes of Variability
This chapter focused on major modes of variability which serve the key role in controlling the regional climate. In terms of tropospheric variability, it defined and discussed ENSO (El Niño Southern Oscillation), NAO (North Atlantic Oscillation), AO and AAO (Arctic Oscillation, Antarctic Oscillation), Indian Monsoon, Indian Ocean Dipole (IOD), PDO (Pacific Decadal Oscillation) and AMO (Atlantic Multidecadal Oscillation). Later it attended stratosphere variability; this constitutes QBO (quasi-biennial oscillation) and SSW (stratospheric sudden warming). Main characteristic features of each of these modes were elaborately discussed
Intraseasonal effects of El Niño-Southern Oscillation on North Atlantic climate
This is the final version. Available from American Meteorological Society via the DOI in this record.It is well established that El Niño-Southern Oscillation (ENSO) impacts the North Atlantic-European (NAE) climate, with the strongest influence in winter. In late winter, the ENSO signal travels via both tropospheric and stratospheric pathways to the NAE sector and often projects onto the North Atlantic Oscillation. However, this signal does not strengthen gradually during winter, and some studies have suggested that the ENSO signal is different between early and late winter and that the teleconnections involved in the early winter subperiod are not well understood. In this study, we investigate the ENSO teleconnection to NAE in early winter (November-December) and characterize the possible mechanisms involved in that teleconnection. To do so, observations, reanalysis data and the output of different types of model simulations have been used. We show that the intraseasonal winter shift of the NAE response to ENSO is detected for both El Niño and La Niña and is significant in both observations and initialized predictions, but it is not reproduced by free-running Coupled Model Intercomparison Project phase 5 (CMIP5) models. The teleconnection is established through the troposphere in early winter and is related to ENSO effects over the Gulf of Mexico and Caribbean Sea that appear in rainfall and reach the NAE region. CMIP5 model biases in equatorial Pacific ENSO sea surface temperature patterns and strength appear to explain the lack of signal in the Gulf of Mexico and Caribbean Sea and, hence, their inability to reproduce the intraseasonal shift of the ENSO signal over Europe.European CommissionEuropean CommissionNatural Environment Research Council (NERC
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Enhanced seasonal forecast skill following stratospheric sudden warmings
Advances in seasonal forecasting have brought widespread
socio-economic benefits. However, seasonal forecast skill
in the extratropics is relatively modest, prompting the
seasonal forecasting community to search for additional
sources of predictability. For over a decade it has been
suggested that knowledge of the state of the stratosphere
can act as a source of enhanced seasonal predictability; long-lived circulation anomalies in the lower stratosphere that follow stratospheric sudden warmings are associated with circulation anomalies in the troposphere that can last up to two months. Here, we show by performing retrospective
ensemble model forecasts that such enhanced predictability
can be realized in a dynamical seasonal forecast system with
a good representation of the stratosphere. When initialized at the onset date of stratospheric sudden warmings, the model forecasts faithfully reproduce the observed mean tropospheric conditions in the months following the stratospheric sudden warmings. Compared with an equivalent set of forecasts that are not initialized during stratospheric sudden warmings, we document enhanced forecast skill for atmospheric circulation patterns, surface temperatures over northern Russia and eastern Canada and North Atlantic precipitation. We suggest
that seasonal forecast systems initialized during stratospheric sudden warmings are likely to yield significantly greater forecast skill in some regions
Seasonal winter forecasts and the stratosphere
Published© 2016 Royal Meteorological Society. We investigate seasonal forecasts of the winter North Atlantic Oscillation (NAO) and their relationship with the stratosphere. Climatological frequencies of sudden stratospheric warming (SSW) and strong polar vortex (SPV) events are well represented and the predicted risk of events varies between 25 and 90% from winter to winter, indicating predictability beyond the deterministic range. The risk of SSW and SPV events relates to predicted NAO as expected, with NAO shifts of -6.5 and +4.8hPa in forecast members containing SSW and SPV events. Most striking of all is that forecast skill of the surface winter NAO vanishes from these hindcasts if members containing SSW events are excluded.This work was supported by the Joint DECC/Defra Met Office
Hadley Centre Climate Programme (GA01101), the UK Public
Weather Service research program and the European Union
Framework 7 SPECS project. The contribution of AYK is funded
by FMI’s tenure track program and the Academy of Finland
under grant 286298
Northern winter climate change: assessment of uncertainty in CMIP5 projections related to stratosphere-troposphere coupling
Journal ArticlePublished versionFuture changes in the stratospheric circulation could have an important impact on northern winter tropospheric climate change, given that sea level pressure (SLP) responds not only to tropospheric circulation variations but also to vertically coherent variations in troposphere-stratosphere circulation. Here we assess northern winter stratospheric change and its potential to influence surface climate change in the Coupled Model Intercomparison Project-Phase 5 (CMIP5) multimodel ensemble. In the stratosphere at high latitudes, an easterly change in zonally averaged zonal wind is found for the majority of the CMIP5 models, under the Representative Concentration Pathway 8.5 scenario. Comparable results are also found in the 1% CO2 increase per year projections, indicating that the stratospheric easterly change is common feature in future climate projections. This stratospheric wind change, however, shows a signi fi cant spread among the models. By using linear regression, we quantify the impact of tropical upper troposphere warming, polar amplification, and the stratospheric wind change on SLP. We find that the intermodel spread in stratospheric wind change contributes substantially to the intermodel spread in Arctic SLP change. The role of the stratosphere in determining part of the spread in SLP change is supported by the fact that the SLP change lags the stratospheric zonally averaged wind change. Taken together, these findings provide further support for the importance of simulating the coupling between the stratosphere and the troposphere, to narrow the uncertainty in the future projection of tropospheric circulation changes
Modelling the cost-effectiveness of public awareness campaigns for the early detection of non-small-cell lung cancer
Background: Survival rates in lung cancer in England are significantly lower than in many similar countries. A range of Be Clear on
Cancer (BCOC) campaigns have been conducted targeting lung cancer and found to improve the proportion of diagnoses at the
early stage of disease. This paper considers the cost-effectiveness of such campaigns, evaluating the effect of both the regional
and national BCOC campaigns on the stage distribution of non-small-cell lung cancer (NSCLC) at diagnosis.
Methods: A natural history model of NSCLC was developed using incidence data, data elicited from clinical experts and model
calibration techniques. This structure is used to consider the lifetime cost and quality-adjusted survival implications of the early
awareness campaigns. Incremental cost-effectiveness ratios (ICERs) in terms of additional costs per quality-adjusted life-years
(QALYs) gained are presented. Two scenario analyses were conducted to investigate the role of changes in the ‘worried-well’
population and the route of diagnosis that might occur as a result of the campaigns.
Results: The base-case theoretical model found the regional and national early awareness campaigns to be associated with QALY
gains of 289 and 178 QALYs and ICERs of d13 660 and d18 173 per QALY gained, respectively. The scenarios found that increases
in the ‘worried-well’ population may impact the cost-effectiveness conclusions.
Conclusions: Subject to the available evidence, the analysis suggests that early awareness campaigns in lung cancer have the
potential to be cost-effective. However, significant additional research is required to address many of the limitations of this study.
In addition, the estimated natural history model presents previously unavailable estimates of the prevalence and rate of disease
progression in the undiagnosed population
Cold gas accretion in galaxies
Evidence for the accretion of cold gas in galaxies has been rapidly
accumulating in the past years. HI observations of galaxies and their
environment have brought to light new facts and phenomena which are evidence of
ongoing or recent accretion:
1) A large number of galaxies are accompanied by gas-rich dwarfs or are
surrounded by HI cloud complexes, tails and filaments. It may be regarded as
direct evidence of cold gas accretion in the local universe. It is probably the
same kind of phenomenon of material infall as the stellar streams observed in
the halos of our galaxy and M31. 2) Considerable amounts of extra-planar HI
have been found in nearby spiral galaxies. While a large fraction of this gas
is produced by galactic fountains, it is likely that a part of it is of
extragalactic origin. 3) Spirals are known to have extended and warped outer
layers of HI. It is not clear how these have formed, and how and for how long
the warps can be sustained. Gas infall has been proposed as the origin. 4) The
majority of galactic disks are lopsided in their morphology as well as in their
kinematics. Also here recent accretion has been advocated as a possible cause.
In our view, accretion takes place both through the arrival and merging of
gas-rich satellites and through gas infall from the intergalactic medium (IGM).
The infall may have observable effects on the disk such as bursts of star
formation and lopsidedness. We infer a mean ``visible'' accretion rate of cold
gas in galaxies of at least 0.2 Msol/yr. In order to reach the accretion rates
needed to sustain the observed star formation (~1 Msol/yr), additional infall
of large amounts of gas from the IGM seems to be required.Comment: To appear in Astronomy & Astrophysics Reviews. 34 pages.
Full-resolution version available at
http://www.astron.nl/~oosterlo/accretionRevie
Small-cell lung cancer in England: trends in survival and chemotherapy using the National Lung Cancer Audit
Background: The purpose of this study was to identify trends in survival and chemotherapy use for individuals with smallcell lung cancer (SCLC) in England using the National Lung Cancer Audit (NLCA).
Methods: We used data from the NLCA database to identify people with histologically proven SCLC from 2004–2011. We
calculated the median survival by stage and assessed whether patient characteristics changed over time. We also assessed whether the proportion of patients with records of chemotherapy and/or radiotherapy changed over time.
Results: 18,513 patients were diagnosed with SCLC in our cohort. The median survival was 6 months for all patients, 1 year for those with limited stage and 4 months for extensive stage. 69% received chemotherapy and this proportion changed very slightly over time (test for trends p = 0.055). Age and performance status of patients remained stable over the study period, but the proportion of patients staged increased (p-value,0.001), mainly because of improved data completeness. There has been an increase in the proportion of patients that had a record of receiving both chemotherapy and radiotherapy each year (from 19% to 40% in limited and from 9% to 21% in extensive stage from 2004 to 2011). Patients who received chemotherapy with radiotherapy had better survival compared with any other treatment (HR 0.24, 95% CI 0.23–0.25).
Conclusion: Since 2004, when the NLCA was established, the proportion of patients with SCLC having chemotherapy has remained static. We have found an upward trend in the proportion of patients receiving both chemotherapy and radiotherapy which corresponded to a better survival in this group, but as it only applied for a small proportion of patients, it was not enough to change the overall survival
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