The ‘new normality’ in research? What message are we conveying our medical students?

The impact of COVID-19 on medical education has been mainly viewed from the perspective of the imposed transition from face-to- face to online delivery of information and the inforced stopping of practical teaching in hospitals.1-5 However, unfortunately, the deleterious effects of COVID-19 on how research findings are obtained, communicated and valued needs also careful consideration. Whilst teaching students that it is a genuinely exciting and unique time to be in medicine, as teachers of a subject entitled ‘Introduction to Research’ to second-year medical students, we feel particularly worried about what the handling of the pandemia is transmitting our future physicians. Now, more than ever before, scholars need to reaffirm the importance on how research findings are obtained and communicated

Systematic review and case series: flexible sigmoidoscopy identifies most cases of checkpoint inhibitor‐induced colitis

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149542/1/apt15263_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149542/2/apt15263.pd

Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study

: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI

La splénectomie partielle à l'ère de la chirurgie minimalement invasive: expérience actuelle avec la laparoscopie et la robotique

La splénectomie partielle est une technique visant à réséquer du tissu splénique tout en laissant suffisamment de parenchyme afin d’assurer les fonctions immunes de la rate. Alors que la laparoscopie constitue l’approche de choix pour la splénectomie totale, la splénectomie partielle laparoscopique est restée une technique marginale. Notre but était de réaliser une revue de la littérature quant à l’indication et la faisabilité de cette technique à la lumière des récentes avancées en chirurgie minimalement invasive. Nous démontrons, dans ce travail, qu’il y a un réel intérêt pour la splénectomie partielle laparoscopique et également robotique, pour des chirurgies électives visant à retirer des lésions focales ou à réduire le volume de la rate. Les résultats de la splénectomie partielle laparoscopique et robotique sont similaires à ceux rapportés dans la littérature pour la technique ouverte

Platelet-induced cell signaling during Liver regeneration

La régénération hépatique est à l'origine de la plasticité du foie après une lésion et le dysfonctionnement de ce processus peut aboutir à l'insuffisance hépatocellulaire. La compréhension des mécanismes sous-jacents à la régénération hépatique est primordiale pour le développement de thérapies permettant de moduler ce processus. Il a été rapporté que les plaquettes sont impliquées dans l'initiation de la régénération hépatique, une étape hautement régulée de ce processus. Nous avons démontré qu'après hépatectomie, les plaquettes initiaient la régénération du foie au travers d'une interaction avec les cellules endothéliales sinusoïdales hépatiques et stimulaient ces cellules à relâcher de l'interleukine 6, qui agissait à son tour sur les cellules hépatiques étoilées et favorisait leur relâchement de facteur de croissance hépatique. Ces observations apportent de nouveaux éléments sur l'implication des plaquettes dans le processus de régénération hépatique et pourraient aboutir à de nouvelles thérapies en cas d'insuffisance hépatocellulaire

Systematic reviews and meta-analyses on robotic single site cholecystectomy: can we conclude that the procedure is safe?

Single-Site® technology for da Vinci® Surgical Systems has been used since 2010 for cholecystectomy. Recent systematic reviews and meta-analyses emphase that this technique is safe, particularly regarding the risk of port-site hernia. However, several authors reported an increased risk of incisional hernia after Single-Site® technology cholecystectomy. This can be explain by incision size but also by specific factors. Indeed, articles included for systematic reviews and meta-analyses had short follow-up and were not focused on long-term complications. Outcomes of meta-analyses should be carefully interpreted and port site-hernia looked forward in any new trials on this topic

Hernies géantes avec perte de droit de cité : comment préparer au mieux les patients ?

Giant hernias with loss of domain induce physiological modifications that impair quality of life and make more complex their surgical management. A good preparation of patients before surgery is the key to an eventless postoperative course. The progressive pre-operative pneumoperitoneum (PPP) is one of the described abdominal augmentation protocols which can help patients to tolerate hernia content reintegration and avoid components separation technique during hernia repair. This article describes the management of these complex patients. We also report the case of a patient who follows successfully a PPP protocol