Hepatic encephalopathy and atypical cortical involvement in cranial MRI: Case report

Hepatik ensefalopati karaciğer fonksiyon bozukluğuna bağlı olarak hastalarda nöropsikiyatrik belirtilerin gelişimi ile karakterizedir. Siroz, portal hipertansiyon veya porto-sistemik şantlar ve akut karaciğer yetmezliği durumlarında gelişebilir. Hafif mental durum bozukluklarından derin komaya kadar değişen geniş bir klinik tablo ile ortaya çıkabilir. Manyetik rezonans görüntüleme (MRG) başta olmak üzere nöro-görüntüleme teknikleri hepatik ensefalopati tanısında kullanılabilir. Sağlıklı bireylerde kolayca metabolize edilebilen maddelerin birikimine bağlı olarak özellikle T1 ağırlıklı MRG'de iki yanlı globus pallidus yapılarında sinyal artışı izlenir. Hepatik ensefalopatide kortikal tutulum oldukça nadir bildirilmiştir. Bu yazıda kortikal ve subkortikal yapıların tutulumu ile seyreden bir hepatik ensefalopati olgusu sunulmuştur.Hepatic encephalopathy is characterized by neuropsychiatric abnormalities occurring in patients with liver dysfunction. It most commonly occurs in association with cirrhosis, portal hypertension, portal-systemic shunts and acute liver failure. Clinical features of hepatic encephalopathy varies between mild cognitive impairment to deep coma. Several neuroimaging techniques, especially magnetic resonance imaging (MRI), may eventually be useful for the diagnosis of hepatic encephalopathy. Cranial MRI may demonstrate high signal intensity in the bilateral globus pallidum on T1-weighted images. Cortical involvement due to hepatic encephalopathy is rarely reported in the literature. We presented here a case of hepatic encephalopathy with cortical and subcortical involvement

Serum IGF-1 and IGFBP-3 Levels in Healthy Children Between 0 and 6 Years of Age

Objective: Along with growth hormone (GH) levels, measurements of serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) are used in the diagnosis of GH deficiency and in monitoring the efficacy and safety of long-term GH treatment. The purpose of the present study was to establish reference values for serum IGF-1 and IGFBP-3 in healthy Turkish children less than 6 years of age

Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis

OBJECTIVE: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing–remitting form of the disease. In this study we aimed to examine the value of each evoked potential to demonstrate the demyelinating lesions in a homogenous group of patients with relapsing remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities. METHODS: Twenty patients with relapsing remitting multiple sclerosis and ten healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogenous group. Visual, somatosensory and motor evoked potentials were measured and EDSS scores of the patients were calculated. RESULTS: Of 20 patients, 15 patients(75%) had VEP abnormality, 14 patients (70%) had MEP abnormality and 12 patients (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. The abnormality of evoked potentials also had a correlation with high EDSS scores. CONCLUSION: We concluded that evoked potentials, especially used in combination, are good markers to show the nervous damage in patients with multiple sclerosis

Herpes Zoster Ophthalmicus With Sixth Cranial Nerve Palsy: A Case Report

Scientific BACKGROUND: Herpes zoster ophthalmicus represents aproximately 25% of all zoster infections. However extraocular gaze palsy in association with herpes zoster infection is extremely rare. OBJECTIVE: We presented here a patient who had herpes zoster ophthalmicus with sixth cranial nerve palsy. CASE: The sixty year old patient had suffered from left retroorbital pain, conjunctival congestion and rashes on the left forehead and the nose and developed ipsilateral sixth cranial nerve palsy. RESULT: Herpes zoster virus infection should be taken into consideration in patients with extraocular paralysis and early treatment may prevent such complication

Is inpatient treatment effective for eating disorders in adolescents? Retrospective analysis of a general inpatient psychiatric unit for children and adolescents Yataklı servis tedavisi ergenlerdeki yeme bozukluklarında etkili midir? Bir çocuk ve ergen psikiyatri servisi verilerinin retrospektif analizi

© 2019, Istanbul Universitesi. All rights reserved.Objective: Our study investigated the improvement of the adolescents with eating disorders who have received inpatient treatment at a general psychiatric inpatient unit for children and adolescents. The unit provides milieu therapy in conjunction with medical and other therapeutic interventions in accordance with patients’ needs. Method: All of the adolescents diagnosed with Anorexia Nervosa, Bulimia Nervosa and Binge Eating Disorder according to DSM-IV and received inpatient treatment at the unit between the years 2005-2018 were recruited. Sociodemographic and family variables, individual and familial risks, presence of comorbid psychiatric diagnosis, the duration of treatment, The Children’s Global Assessment Scale (CGAS) and Health of the Nation Outcome Scales-Children and Adolescents (HONOSCA-TR) scores at admission and discharge were retrospectively collected. Results: A total of 19 adolescents were included in the study. Results demonstrated that average duration of stay at the unit was 70.31±19.12 (Mean±SD) days. General functionality measured by the CGAS significantly increased from admission to discharge following psychiatric inpatient treatment. Moreover, there were significant improvement in adolescents with eating disorders as indicated with all of the HONOSCA-TR subscales. Conclusion: These results implicate that long enough inpatient milieu therapy applied with multidisciplinary and multidimensional perspectives might have fostered the improvement of severely affected adolescents with eating disorders

Is inpatient treatment effective for eating disorders in adolescents? Retrospective analysis of a general inpatient psychiatric unit for children and adolescents

© 2019, Istanbul Universitesi. All rights reserved.Objective: Our study investigated the improvement of the adolescents with eating disorders who have received inpatient treatment at a general psychiatric inpatient unit for children and adolescents. The unit provides milieu therapy in conjunction with medical and other therapeutic interventions in accordance with patients’ needs. Method: All of the adolescents diagnosed with Anorexia Nervosa, Bulimia Nervosa and Binge Eating Disorder according to DSM-IV and received inpatient treatment at the unit between the years 2005-2018 were recruited. Sociodemographic and family variables, individual and familial risks, presence of comorbid psychiatric diagnosis, the duration of treatment, The Children’s Global Assessment Scale (CGAS) and Health of the Nation Outcome Scales-Children and Adolescents (HONOSCA-TR) scores at admission and discharge were retrospectively collected. Results: A total of 19 adolescents were included in the study. Results demonstrated that average duration of stay at the unit was 70.31±19.12 (Mean±SD) days. General functionality measured by the CGAS significantly increased from admission to discharge following psychiatric inpatient treatment. Moreover, there were significant improvement in adolescents with eating disorders as indicated with all of the HONOSCA-TR subscales. Conclusion: These results implicate that long enough inpatient milieu therapy applied with multidisciplinary and multidimensional perspectives might have fostered the improvement of severely affected adolescents with eating disorders

11 Eylül 1957 Ankara sel felaketi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Sert, Özlem