248 research outputs found

    Web-based communication tools in a European research project: the example of the TRACE project

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    The multi-disciplinary and international nature of large European projects requires powerful managerial and communicative tools to ensure the transmission of information to the end-users. One such project is TRACE entitled “Tracing Food Commodities in Europe”. One of its objectives is to provide a communication system dedicated to be the central source of information on food authenticity and traceability in Europe. This paper explores the web tools used and communication vehicles offered to scientists involved in the TRACE project to communicate internally as well as to the public. Two main tools have been built: an Intranet and a public website. The TRACE website can be accessed at http://www.trace.eu.org. A particular emphasis was placed on the efficiency, the relevance and the accessibility of the information, the publicity of the website as well as the use of the collaborative utilities. The rationale of web space design as well as integration of proprietary software solutions are presented. Perspectives on the using of web tools in the research projects are discussed

    Windings of the 2D free Rouse chain

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    We study long time dynamical properties of a chain of harmonically bound Brownian particles. This chain is allowed to wander everywhere in the plane. We show that the scaling variables for the occupation times T_j, areas A_j and winding angles \theta_j (j=1,...,n labels the particles) take the same general form as in the usual Brownian motion. We also compute the asymptotic joint laws P({T_j}), P({A_j}), P({\theta_j}) and discuss the correlations occuring in those distributions.Comment: Latex, 17 pages, submitted to J. Phys.

    Topological interactions in systems of mutually interlinked polymer rings

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    The topological interaction arising in interlinked polymeric rings such as DNA catenanes is considered. More specifically, the free energy for a pair of linked random walk rings is derived where the distance RR between two segments each of which is part of a different ring is kept constant. The topology conservation is imposed by the Gauss invariant. A previous approach (M.Otto, T.A. Vilgis, Phys.Rev.Lett. {\bf 80}, 881 (1998)) to the problem is refined in several ways. It is confirmed, that asymptotically, i.e. for large RRGR\gg R_G where RGR_G is average size of single random walk ring, the effective topological interaction (free energy) scales R4\propto R^4.Comment: 16 pages, 3 figur

    Area versus Length Distribution for Closed Random Walks

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    Using a connection between the qq-oscillator algebra and the coefficients of the high temperature expansion of the frustrated Gaussian spin model, we derive an exact formula for the number of closed random walks of given length and area, on a hypercubic lattice, in the limit of infinite number of dimensions. The formula is investigated in detail, and asymptotic behaviours are evaluated. The area distribution in the limit of long loops is computed. As a byproduct, we obtain also an infinite set of new, nontrivial identities.Comment: 17 page

    From Monolith to Microservices: A Classification of Refactoring Approaches

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    While the recently emerged Microservices architectural style is widely discussed in literature, it is difficult to find clear guidance on the process of refactoring legacy applications. The importance of the topic is underpinned by high costs and effort of a refactoring process which has several other implications, e.g. overall processes (DevOps) and team structure. Software architects facing this challenge are in need of selecting an appropriate strategy and refactoring technique. One of the most discussed aspects in this context is finding the right service granularity to fully leverage the advantages of a Microservices architecture. This study first discusses the notion of architectural refactoring and subsequently compares 10 existing refactoring approaches recently proposed in academic literature. The approaches are classified by the underlying decomposition technique and visually presented in the form of a decision guide for quick reference. The review yielded a variety of strategies to break down a monolithic application into independent services. With one exception, most approaches are only applicable under certain conditions. Further concerns are the significant amount of input data some approaches require as well as limited or prototypical tool support.Comment: 13 pages, 4 tables, 2 figures, Software Engineering Aspects of Continuous Development and New Paradigms of Software Production and Deployment, First International Workshop, DEVOPS 2018, Chateau de Villebrumier, France, March 5-6, 2018, Revised Selected Paper

    Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells

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    Diabetes is a global health problem caused primarily by the inability of pancreatic β-cells to secrete adequate levels of insulin. The molecular mechanisms underlying the progressive failure of β-cells to respond to glucose in type-2 diabetes remain unresolved. Using a combination of transcriptomics and proteomics, we find significant dysregulation of major metabolic pathways in islets of diabetic βV59M mice, a non-obese, eulipidaemic diabetes model. Multiple genes/proteins involved in glycolysis/gluconeogenesis are upregulated, whereas those involved in oxidative phosphorylation are downregulated. In isolated islets, glucose-induced increases in NADH and ATP are impaired and both oxidative and glycolytic glucose metabolism are reduced. INS-1 β-cells cultured chronically at high glucose show similar changes in protein expression and reduced glucose-stimulated oxygen consumption: targeted metabolomics reveals impaired metabolism. These data indicate hyperglycaemia induces metabolic changes in β-cells that markedly reduce mitochondrial metabolism and ATP synthesis. We propose this underlies the progressive failure of β-cells in diabetes.Peer reviewe

    Internet of Tangible Things: Workshop on Tangible Interaction with the Internet of Things

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    The rise of the Internet of Things (IoT) brings abundant new opportunities to create more effective and pleasing tangible user interfaces that capitalize on intuitive interaction in the physical world, whilst utilizing capabilities of sensed data and Internet connectivity. However, with these new opportunities come new challenges; little is still known how to best design tangible IoT interfaces that simultaneously provide engaging user experiences and foster a sense of understanding about the often-complex functionality of IoT systems. How should we map previous taxonomies and design principles for tangible interaction into the new landscape of IoT systems? This workshop will bring together a community of researchers from the fields of IoT and tangible interaction, in order to explore and discuss how parallels between tangible interaction and the properties of IoT systems can best be capitalised on as HCI research moves increasingly toward the Internet of Tangible Things (IoTT). Through ideation and discussion, the workshop will function as a springboard for the community to begin creating new taxonomies and design considerations for the emerging IoTT

    A generic method for estimating and smoothing multispecies biodiversity indices using intermittent data

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    Biodiversity indicators summarise extensive, complex ecological data sets and are important in influencing government policy. Component data consist of time-varying indices for each of a number of different species. However, current biodiversity indicators suffer from multiple statistical shortcomings. We describe a state-space formulation for new multispecies biodiversity indicators, based on rates of change in the abundance or occupancy probability of the contributing individual species. The formulation is flexible and applicable to different taxa. It possesses several advantages, including the ability to accommodate the sporadic unavailability of data, incorporate variation in the estimation precision of the individual species’ indices when appropriate, and allow the direct incorporation of smoothing over time. Furthermore, model fitting is straightforward in Bayesian and classical implementations, the latter adopting either efficient Hidden Markov modelling or the Kalman filter. Conveniently, the same algorithms can be adopted for cases based on abundance or occupancy data—only the subsequent interpretation differs. The procedure removes the need for bootstrapping which can be prohibitive. We recommend which of two alternatives to use when taxa are fully or partially sampled. The performance of the new approach is demonstrated on simulated data, and through application to three diverse national UK data sets on butterflies, bats and dragonflies. We see that uncritical incorporation of index standard errors should be avoided

    Distribution maps of cetacean and seabird populations in the North‐East Atlantic

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    1. Distribution maps of cetaceans and seabirds at basin and monthly scales are needed for conservation and marine management. These are usually created from standardized and systematic aerial and vessel surveys, with recorded animal den- sities interpolated across study areas. However, distribution maps at basin and monthly scales have previously not been possible because individual surveys have restricted spatial and temporal coverage. 2. This study develops an alternative approach consisting of: (a) collating diverse survey data to maximize spatial and temporal coverage, (b) using detection func- tions to estimate variation in the surface area covered (km2) among these surveys, standardizing measurements of effort and animal densities, and (c) developing species distribution models (SDM) that overcome issues with heterogeneous and uneven coverage. 3. 2.68 million km of survey data in the North-East Atlantic between 1980 and 2018 were collated and standardized. SDM using Generalized Linear Models and General Estimating Equations in a hurdle approach were developed. Distribution maps were then created for 12 cetacean and 12 seabird species at 10 km and monthly resolution. Qualitative and quantitative assessment indicated good model performance. 4. Synthesis and applications. This study provides the largest ever collation and standardization of diverse survey data for cetaceans and seabirds, and the most comprehensive distribution maps of these taxa in the North-East Atlantic. These distribution maps have numerous applications including the identification of im- portant areas needing protection, and the quantification of overlap between vul- nerable species and anthropogenic activities. This study demonstrates how the analysis of existing and diverse survey data can meet conservation and marine management needs.Versión del editor4,7
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