27,123 research outputs found
Planning a DSN support section technical library
The planning procedure being used to establish a technical library for the Deep Space Network support section is described. The inventory and survey methods employed are described and the preliminary results of these methods are discussed
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An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration.
Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of progression. The secondary aim was to determine the relationship between disease severity grade and the observed functional and structural deficits. Methods: A total of 100 participants whose AMD status varied from early to advanced were recruited. Visual function was assessed using cone dark adaptation, 14 Hz flicker and chromatic threshold tests and retinal structure was assessed by measuring drusen volume and macular thickness. The predictive value of the tests was estimated using ordinal regression analysis. Group comparisons were assessed using analysis of covariance. Results: Change in cone dark adaptation (cone Ï„) and yellow-blue (YB) chromatic sensitivity were independent predictors for AMD progression risk (cone Ï„, pseudo R2 = 0.35, P < 0.001; YB chromatic threshold, pseudo R2 = 0.16, P < 0.001). The only structural predictor was foveal thickness (R2 = 0.05, P = 0.047). Chromatic sensitivity and cone dark adaptation were also the best functional tests at distinguishing between severity groups. Drusen characteristics clearly differentiated between participants with early and advanced disease, but were not able to differentiate between those with early AMD and controls. Mean differences in retinal thickness existed between severity groups at the foveal (P = 0.040) and inner (P = 0.001) subfields. Conclusions: This study indicates that cone Ï„, YB chromatic threshold and foveal thickness are independent predictors of likely risk of AMD progression
Panning for gold: designing pedagogically-inspired learning nuggets
Tools to support teachers and learning technologists in the creation of effective learning designs are currently in their infancy. This paper describes a metadata model, devised to assist in the conception and design of new learning activities, that has been developed, used and evaluated over a period of three years. The online tool that embodies this model was not originally intended to produce runtime executable code such as IMS-LD, but rather focussed on assisting teachers in the thought processes involved in selecting appropriate methods, tools, student activities and assessments to suit the required learning objectives. Subsequently, we have modified the RELOAD editor such that the output from our tool can be translated into IMS-LD. The contribution of this paper is the comparison of our data model with that of IMS-LD, and the analysis of how each can inform the other
Defect Formation and Kinetics of Atomic Terrace Merging
Pairs of atomic scale terraces on a single crystal metal surface can be made
to merge controllably under suitable conditions to yield steps of double height
and width. We study the effect of various physical parameters on the formation
of defects in a kinetic model of step doubling. We treat this manifestly non-
equilibrium problem by mapping the model onto a 1-D random sequential
adsorption problem and solving this analytically. We also do simulations to
check the validity of our treatment. We find that our treatment effectively
captures the dynamic evolution and the final state of the surface morphology.
We show that the number and nature of the defects formed is controlled by a
single dimensionless parameter . For close to one we show that the
fraction of defects rises linearly with as . We also show that one can arrive at the final state faster and with
fewer defects by changing the parameter with time.Comment: 17 pages, 8 figures. To be submitted to Phys. Rev.
Dynamics and Steady States in excitable mobile agent systems
We study the spreading of excitations in 2D systems of mobile agents where
the excitation is transmitted when a quiescent agent keeps contact with an
excited one during a non-vanishing time. We show that the steady states
strongly depend on the spatial agent dynamics. Moreover, the coupling between
exposition time () and agent-agent contact rate (CR) becomes crucial to
understand the excitation dynamics, which exhibits three regimes with CR: no
excitation for low CR, an excited regime in which the number of quiescent
agents (S) is inversely proportional to CR, and for high CR, a novel third
regime, model dependent, here S scales with an exponent , with
being the scaling exponent of with CR
Slow epidemic extinction in populations with heterogeneous infection rates
We explore how heterogeneity in the intensity of interactions between people
affects epidemic spreading. For that, we study the
susceptible-infected-susceptible model on a complex network, where a link
connecting individuals and is endowed with an infection rate
proportional to the intensity of their contact
, with a distribution taken from face-to-face experiments
analyzed in Cattuto (PLoS ONE 5, e11596, 2010). We find an extremely
slow decay of the fraction of infected individuals, for a wide range of the
control parameter . Using a distribution of width we identify two
large regions in the space with anomalous behaviors, which are
reminiscent of rare region effects (Griffiths phases) found in models with
quenched disorder. We show that the slow approach to extinction is caused by
isolated small groups of highly interacting individuals, which keep epidemic
alive for very long times. A mean-field approximation and a percolation
approach capture with very good accuracy the absorbing-active transition line
for weak (small ) and strong (large ) disorder, respectively
A Mesolithic settlement site at Howick, Northumberland: a preliminary report
Excavations at a coastal site at Howick during 2000 and 2002 have revealed evidence for a substantial Mesolithic settlement and a Bronze Age cist cemetery. Twenty one radiocarbon determinations of the earlier eighth millennium BP (Cal.) indicate that the Mesolithic site is one of the earliest known in northern Britain. An 8m core of sediment was recovered from stream deposits adjacent to the archaeological site which provides information on local environmental conditions. Howick offers a unique opportunity to understand aspects of hunter-gatherer colonisation and settlement during a period of rapid palaeogeographical change around the margins of the North Sea basin, at a time when it was being progressively inundated by the final stages of the postglacial marine transgression. The cist cemetery will add to the picture of Bronze Age occupation of the coastal strip and again reveals a correlation between the location of Bronze Age and Mesolithic sites which has been observed elsewhere in the region
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