98 research outputs found
Análise ergonômica do trabalho agrícola familiar na produção de leite.
Este artigo trata da metodologia utilizada em uma intervenção ergonômica sobre organização do trabalho em Unidades de Produção Agrícola Familiar (UPAF) produtoras de leite de origem bovina, na região oeste da França. Apresenta-se a metodologia utilizada, uma combinação de jornadas de observação e análise do trabalho e jornadas de formação-ação. Discutem-se a Crônica de Ação e o Plano de Utilização das Instalações (PUI), bem como a utilização destes no processo de conscientização do agricultor sobre a complexidade de seu trabalho. Apresenta-se a análise da "supervisão do rebanho", devido ao seu alto grau de complexidade e importância para o desempenho da produção de leite, explorando de que forma certos arranjos espaciais podem favorecer as condições para a realização desta tarefa. Na análise do trabalho agrícola familiar privilegia-se o olhar complexo sobre a situação de trabalho, visando identificar os determinantes, as fontes de variabilidade e as estratégias adotadas
A low-cost HPV immunochromatographic assay to detect high-grade cervical intraepithelial neoplasia
Objective
To evaluate the reproducibility and accuracy of the HPV16/18-E6 test.
Methods
The study population was comprised of 448 women with a previously abnormal Pap who were referred to the Barretos Cancer Hospital (Brazil) for diagnosis and treatment. Two cervical samples were collected immediately before colposcopy, one for the hr-HPV-DNA test and cytology and the other for the HPV16/18-E6 test using high-affinity monoclonal antibodies (mAb). Women with a histologic diagnosis of cervical intraepithelial neoplasia grade 2 or 3 were considered to be positive cases. Different strategies using a combination of screening methods (HPV-DNA) and triage tests (cytology and HPV16/18-E6) were also examined and compared.
Results
The HPV16/18-E6 test exhibited a lower positivity rate compared with the HPV-DNA test (19.0% vs. 29.3%, p<0.001) and a moderate/high agreement (kappa = 0.68, 95% CI: 0.60-0.75). It also exhibited a significantly lower sensitivity for CIN2+ and CIN3+ detection compared to the HPV-DNA test and a significantly higher specificity. The HPV16/18-E6 test was no different from cytology in terms of sensitivity, but it exhibited a significantly higher specificity in comparison to ASCH+. A triage test after HPV-DNA detection using the HPV16/18-E6 test exhibited a significantly higher specificity compared with a triage test of ASCH+ to CIN2+ (91.8% vs. 87.4%, p = 0.04) and CIN3+ (88.6% vs. 84.0%, p = 0.05).
Conclusion
The HPV16/18-E6 test exhibited moderate/high agreement with the HPV-DNA test but lower sensitivity and higher specificity for the detection of CIN2+ and CIN3+. In addition, its performance was quite similar to cytology, but because of the structural design addressed for the detection of HPV16/18-E6 protein, the test can miss some CIN2/3+ lesions caused by other high-risk HPV types.Cancer Prevention Department, Center for the Researcher Support and Pathology Department of the Barretos Cancer Hospital. This study was supported by CNPq 573799/2008-3 and FAPESP 2008/57889-1info:eu-repo/semantics/publishedVersio
The ThomX project status
Work supported by the French Agence Nationale de la recherche as part of the program EQUIPEX under reference ANR-10-EQPX-51, the Ile de France region, CNRS-IN2P3 and Université Paris Sud XI - http://accelconf.web.cern.ch/AccelConf/IPAC2014/papers/wepro052.pdfA collaboration of seven research institutes and an industry has been set up for the ThomX project, a compact Compton Backscattering Source (CBS) based in Orsay - France. After a period of study and definition of the machine performance, a full description of all the systems has been provided. The infrastructure work has been started and the main systems are in the call for tender phase. In this paper we will illustrate the definitive machine parameters and components characteristics. We will also update the results of the different technical and experimental activities on optical resonators, RF power supplies and on the electron gun
Drying colloidal systems: laboratory models for a wide range of applications
The drying of complex fluids provides a powerful insight into phenomena that take place on time and length scales not normally accessible. An important feature of complex fluids, colloidal dispersions and polymer solutions is their high sensitivity to weak external actions. Thus, the drying of complex fluids involves a large number of physical and chemical processes. The scope of this review is the capacity to tune such systems to reproduce and explore specific properties in a physics laboratory. A wide variety of systems are presented, ranging from functional coatings, food science, cosmetology, medical diagnostics and forensics to geophysics and art
Agglomeration/granulation in food powder production
Agglomeration is a unit operation during which native particles are assembled to form bigger agglomerates, in which the original particle can still be distinguished. Agglomeration is considered to improve the functionality of food powders. Both physical and physicochemical phenomena must be considered when describing agglomeration. Food powders react when exposed to high temperatures and/or the addition of liquid, that is, their molecules can undergo irreversible physicochemical changes under these conditions. In this chapter, the agglomeration of food powders is described, from the generic concepts through to specifi citiesassociated with their physicochemical reactivity
Fractionnement d\u27un homogenat de nerf sciatique de souris normale, trembler et quaking sur gradient continu de saccharose.
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