779 research outputs found
Advanced Diagnostics for the Study of Linearly Polarized Emission. II: Application to Diffuse Interstellar Radio Synchrotron Emission
Diagnostics of polarized emission provide us with valuable information on the
Galactic magnetic field and the state of turbulence in the interstellar medium,
which cannot be obtained from synchrotron intensity alone. In Paper I (Herron
et al. 2017b), we derived polarization diagnostics that are rotationally and
translationally invariant in the - plane, similar to the polarization
gradient. In this paper, we apply these diagnostics to simulations of ideal
magnetohydrodynamic turbulence that have a range of sonic and Alfv\'enic Mach
numbers. We generate synthetic images of Stokes and for these
simulations, for the cases where the turbulence is illuminated from behind by
uniform polarized emission, and where the polarized emission originates from
within the turbulent volume. From these simulated images we calculate the
polarization diagnostics derived in Paper I, for different lines of sight
relative to the mean magnetic field, and for a range of frequencies. For all of
our simulations, we find that the polarization gradient is very similar to the
generalized polarization gradient, and that both trace spatial variations in
the magnetoionic medium for the case where emission originates within the
turbulent volume, provided that the medium is not supersonic. We propose a
method for distinguishing the cases of emission coming from behind or within a
turbulent, Faraday rotating medium, and a method to partly map the rotation
measure of the observed region. We also speculate on statistics of these
diagnostics that may allow us to constrain the physical properties of an
observed turbulent region.Comment: 34 pages, 25 figures, accepted for publication in Ap
Higher-Spin Fermionic Gauge Fields and Their Electromagnetic Coupling
We study the electromagnetic coupling of massless higher-spin fermions in
flat space. Under the assumptions of locality and Poincare invariance, we
employ the BRST-BV cohomological methods to construct consistent
parity-preserving off-shell cubic 1-s-s vertices. Consistency and
non-triviality of the deformations not only rule out minimal coupling, but also
restrict the possible number of derivatives. Our findings are in complete
agreement with, but derived in a manner independent from, the
light-cone-formulation results of Metsaev and the string-theory-inspired
results of Sagnotti-Taronna. We prove that any gauge-algebra-preserving vertex
cannot deform the gauge transformations. We also show that in a local theory,
without additional dynamical higher-spin gauge fields, the non-abelian vertices
are eliminated by the lack of consistent second-order deformations.Comment: 44 pages; references added, minor changes made, to appear in JHE
Galilean quantum gravity with cosmological constant and the extended q-Heisenberg algebra
We define a theory of Galilean gravity in 2+1 dimensions with cosmological
constant as a Chern-Simons gauge theory of the doubly-extended Newton-Hooke
group, extending our previous study of classical and quantum gravity in 2+1
dimensions in the Galilean limit. We exhibit an r-matrix which is compatible
with our Chern-Simons action (in a sense to be defined) and show that the
associated bi-algebra structure of the Newton-Hooke Lie algebra is that of the
classical double of the extended Heisenberg algebra. We deduce that, in the
quantisation of the theory according to the combinatorial quantisation
programme, much of the quantum theory is determined by the quantum double of
the extended q-deformed Heisenberg algebra.Comment: 22 page
The GALFA-HI Compact Cloud Catalog
We present a catalog of 1964 isolated, compact neutral hydrogen clouds from
the Galactic Arecibo L-Band Feed Array Survey Data Release One (GALFA-HI DR1).
The clouds were identified by a custom machine-vision algorithm utilizing
Difference of Gaussian kernels to search for clouds smaller than 20'. The
clouds have velocities typically between |VLSR| = 20-400 km/s, linewidths of
2.5-35 km/s, and column densities ranging from 1 - 35 x 10^18 cm^-2. The
distances to the clouds in this catalog may cover several orders of magnitude,
so the masses may range from less than a Solar mass for clouds within the
Galactic disc, to greater than 10^4 Solar Masses for HVCs at the tip of the
Magellanic Stream. To search for trends, we separate the catalog into five
populations based on position, velocity, and linewidth: high velocity clouds
(HVCs); galaxy candidates; cold low velocity clouds (LVCs); warm, low
positive-velocity clouds in the third Galactic Quadrant; and the remaining warm
LVCs. The observed HVCs are found to be associated with previously-identified
HVC complexes. We do not observe a large population of isolated clouds at high
velocities as some models predict. We see evidence for distinct histories at
low velocities in detecting populations of clouds corotating with the Galactic
disc and a set of clouds that is not corotating.Comment: 34 Pages, 9 Figures, published in ApJ (2012, ApJ, 758, 44), this
version has the corrected fluxes and corresponding flux histogram and masse
Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors.
Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound by EWS-FLI1. Here we show that fusions between EWS and GGAA-repeat-targeted engineered zinc finger arrays (ZFAs) can function at least as efficiently as EWS-FLI1 for converting hundreds of GGAA repeats into active enhancers in a Ewing sarcoma precursor cell model. Furthermore, a fusion of a KRAB domain to a ZFA can silence GGAA microsatellite enhancers genome wide in Ewing sarcoma cells, thereby reducing expression of EWS-FLI1-activated genes. Remarkably, this KRAB-ZFA fusion showed selective toxicity against Ewing sarcoma cells compared with non-Ewing cancer cells, consistent with its Ewing sarcoma-specific impact on the transcriptome. These findings demonstrate the value of ZFAs for functional annotation of repeats and illustrate how aberrant microsatellite activities might be regulated for potential therapeutic applications
A Note on Vectorial AdS/CFT Duality for Spin- Boundary Theory
The vectorial holographic correspondences between higher-spin theories in
AdS and free vector models on the boundary are extended to the cases where
the latter is described by free massless spin- field. The dual higher-spin
theory in the bulk does not include gravity and can only be defined on rigid
AdS background with boundary. We discuss various properties of these
rather special higher-spin theories and calculate their one-loop free energies.
We show that the result is proportional to the same quantity for spin-
doubleton treated as if it is a AdS field. Finally, we consider even more
special case where the boundary theory itself is given by an infinite tower of
massless higher-spin fields.Comment: 27 pages, version to appear in JHE
Maxwell-like Lagrangians for higher spins
We show how implementing invariance under divergence-free gauge
transformations leads to a remarkably simple Lagrangian description of massless
bosons of any spin. Our construction covers both flat and (A)dS backgrounds and
extends to tensors of arbitrary mixed-symmetry type. Irreducible and traceless
fields produce single-particle actions, while whenever trace constraints can be
dispensed with the resulting Lagrangians display the same reducible,
multi-particle spectra as those emerging from the tensionless limit of free
open-string field theory. For all explored options the corresponding kinetic
operators take essentially the same form as in the spin-one, Maxwell case.Comment: 77 pages, revised version. Erroneous interpretation and proof of the
gauge-fixing procedure for mixed-symmetry fields corrected. As a consequence,
the mixed-symmetry, one-particle Lagrangians are to be complemented with
conditions on the divergences of the fields; all other conclusions unchanged.
Additional minor changes including references added. To appear in JHE
Effect of promoter architecture on the cell-to-cell variability in gene expression
According to recent experimental evidence, the architecture of a promoter,
defined as the number, strength and regulatory role of the operators that
control the promoter, plays a major role in determining the level of
cell-to-cell variability in gene expression. These quantitative experiments
call for a corresponding modeling effort that addresses the question of how
changes in promoter architecture affect noise in gene expression in a
systematic rather than case-by-case fashion. In this article, we make such a
systematic investigation, based on a simple microscopic model of gene
regulation that incorporates stochastic effects. In particular, we show how
operator strength and operator multiplicity affect this variability. We examine
different modes of transcription factor binding to complex promoters
(cooperative, independent, simultaneous) and how each of these affects the
level of variability in transcription product from cell-to-cell. We propose
that direct comparison between in vivo single-cell experiments and theoretical
predictions for the moments of the probability distribution of mRNA number per
cell can discriminate between different kinetic models of gene regulation.Comment: 35 pages, 6 figures, Submitte
Interstellar MHD Turbulence and Star Formation
This chapter reviews the nature of turbulence in the Galactic interstellar
medium (ISM) and its connections to the star formation (SF) process. The ISM is
turbulent, magnetized, self-gravitating, and is subject to heating and cooling
processes that control its thermodynamic behavior. The turbulence in the warm
and hot ionized components of the ISM appears to be trans- or subsonic, and
thus to behave nearly incompressibly. However, the neutral warm and cold
components are highly compressible, as a consequence of both thermal
instability in the atomic gas and of moderately-to-strongly supersonic motions
in the roughly isothermal cold atomic and molecular components. Within this
context, we discuss: i) the production and statistical distribution of
turbulent density fluctuations in both isothermal and polytropic media; ii) the
nature of the clumps produced by thermal instability, noting that, contrary to
classical ideas, they in general accrete mass from their environment; iii) the
density-magnetic field correlation (or lack thereof) in turbulent density
fluctuations, as a consequence of the superposition of the different wave modes
in the turbulent flow; iv) the evolution of the mass-to-magnetic flux ratio
(MFR) in density fluctuations as they are built up by dynamic compressions; v)
the formation of cold, dense clouds aided by thermal instability; vi) the
expectation that star-forming molecular clouds are likely to be undergoing
global gravitational contraction, rather than being near equilibrium, and vii)
the regulation of the star formation rate (SFR) in such gravitationally
contracting clouds by stellar feedback which, rather than keeping the clouds
from collapsing, evaporates and diperses them while they collapse.Comment: 43 pages. Invited chapter for the book "Magnetic Fields in Diffuse
Media", edited by Elisabete de Gouveia dal Pino and Alex Lazarian. Revised as
per referee's recommendation
The shear viscosity of carbon fibre suspension and its application for fibre length measurement
The viscosity of short carbon fibre suspensions in glycerol aqueous solution was measured using a bespoke vane-in-cup viscometer, where the carbon fibre has an aspect ratio from 450 to 2209. In the semi-concentrated regime, nL3 ranging from 20 to 4400, the suspensions demonstrated strong shear-thinning characteristics particularly at higher concentrations. The shear-thinning characteristic is strongly related to the crowding factor proposed by Kerekes, indicating that non-hydrodynamic interactions occur in the suspensions. The influence of fibre bending on viscosity emerges when the bending ratio is lower than 0.0028. An empirical model based on transient network formation and rupture was proposed and used to correlate the relative viscosity with fibre concentration nL3 and shear rate. Based on the model, a viscosity method is established to analyse the fibre length by measuring the viscosity of the fibre suspension using a bespoke vane-in-cup viscometer
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