3,611 research outputs found

    Erratum: Virial coefficients and demixing in the Asakura-Oosawa model (vol 142, 014902, 2015)

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    © 2015 AIP Publishing LLCDepto. de Estructura de la Materia, Física Térmica y ElectrónicaFac. de Ciencias FísicasTRUEpu

    Service discovery

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    Semantic service discovery is the process of locating Web Services based on the description of their functional and non-functional semantics. Both service oriented computing and the semantic Web envision intelligent agents to proactively pursue this task on behalf of their clients. Service discovery can be performed in different ways depending on the service description framework, on means of service selection, and on its coordination through assisted mediation or in a peer-to-peer fashion.info:eu-repo/semantics/publishedVersio

    Predicting Post-Discharge Complications in Cardiothoracic Surgery: a Clinical Decision Support System to Optimize Remote Patient Monitoring Resources

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    Cardiac surgery patients are highly prone to severe complications post-discharge. Close follow-up through remote patient monitoring can help detect adverse outcomes earlier or prevent them, closing the gap between hospital and home care. However, equipment is limited due to economic and human resource constraints. This issue raises the need for efficient risk estimation to provide clinicians with insights into the potential benefit of remote monitoring for each patient. Standard models, such as the EuroSCORE, predict the mortality risk before the surgery. While these are used and validated in real settings, the models lack information collected during or following the surgery, determinant to predict adverse outcomes occurring further in the future. This paper proposes a Clinical Decision Support System based on Machine Learning to estimate the risk of severe complications within 90 days following cardiothoracic surgery discharge, an innovative objective underexplored in the literature. Health records from a cardiothoracic surgery department regarding 5 045 patients (60.8% male) collected throughout ten years were used to train predictive models. Clinicians' insights contributed to improving data preparation and extending traditional pipeline optimization techniques, addressing medical Artificial Intelligence requirements. Two separate test sets were used to evaluate the generalizability, one derived from a patient-grouped 70/30 split and another including all surgeries from the last available year. The achieved Area Under the Receiver Operating Characteristic curve on these test sets was 69.5% and 65.3%, respectively. Also, additional testing was implemented to simulate a real-world use case considering the weekly distribution of remote patient monitoring resources post-discharge. Compared to the random resource allocation, the selection of patients with respect to the outputs of the proposed model was proven beneficial, as it led to a higher number of high-risk patients receiving remote monitoring equipment.info:eu-repo/semantics/publishedVersio

    Estimating the time-dependent performance of nanocatalysts in fuel cells based on a cost-normalization approach

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    CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESResearchers have developed new catalysts for fuel cells (FC), whose performances are compared after applying different normalization procedures. However, there is not a standard procedure. The current produced from CO electrooxidation was compared for Pt4271119801988CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES454516/2014-2SEM INFORMAÇÃOThe authors acknowledge financial assistance from CNPq (grant No. 454516/2014-2), FUNDECT (grant No. 026/2015), CAPES and FINE

    Reliability of the resonance frequency analysis values in new prototype transepithelial abutments: A prospective clinical study

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    Resonance frequency analysis (RFA) requires abutment disconnection to monitor implant stability. To overcome this limitation, an experimental transepithelial abutment was designed to allow a SmartPeg to be screwed onto it, in order to determine the prototype abutments repeatability and reproducibility using Osstell ISQ and to assess whether implant length and diameter have an influence on the reliability of these measurements. RFA was conducted with a SmartPeg screwed directly into the implant and onto experimental abutments of different heights of 2, 3.5 and 5 mm. A total of 32 patients (116 implants) were tested. RFA measurements were taken twice for each group from mesial, distal, buccal and palatal/lingual surfaces. Mean values and SD were calculated and Intraclass Correlation Coefficients (ICC) (p < 0.05, IC 95%). The implant stability quotient (ISQ) mean values were 72.581 measured directly to implant and 72.899 (2 mm), 72.391 (3.5 mm) and 71.458 (5 mm) measured from the prototypes. ICC between measurements made directly to implant and through 2-, 3.5-and 5-mm abutments were 0.908, 0.919 and 0.939, respectively. RFA values registered through the experimental transepithelial abutments achieved a high reliability. Neither the implant length nor the diameter had any influence on the measurements’ reliability

    Primary dispersal of Cytisus multiflorus seeds

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    Current work relates to the primary dispersal of Cytisus multiflorus seeds: seed production, dispersal mechanisms, distribution of seed after dissemination and dormancy were investigated. The distribution of seed was recorded before collection; seed viabilaty and dormancy were assessed. The results indicate that the dispersion is assisted by an explosive dehiscence of the seed pod in that only 35% of the seed drop directly beneath the plant, the remainder falling further away, some reaching distances greater than 3 m. Dormancy index was found to be 98.9%.[es] En el presente trabajo se estudia la dispersión primaria de las semillas de Cytisus multiflorus: cuantificación de la producción, mecanismos de dispersión, distribución de las semillas tras la diseminación, y su estado de latencia. Para ello se colocaron dispositivos de recogida de las semillas debajo y alrededor de las plantas, anotando la cantidad y distancia de la calda; posteriormente eran sembradas para comprobarla viabilidad y dormición de las semillas. Los resultados indican la existencia de una dispersión por dehiscencia explosiva; solamente el 35% de las semillas caen bajo la planta, haciéndolo el resto en sus alrededores; algunas alcanzaron distancias superiores a los 3 m. El índice de dormición es de 98.9%. [fr] Dans le présent travail on étudie la dispersion primaire des graines de Cytisus multiflorus: quantification de la production, mécanismes de dispersion, distribution des graines après la dissémination et leur état de latence. Pour ce faire on a placé des dispositifs de récolte des graines au dessous et autour des plantes, enregistrant la quantité et la distance de la chute; après elles étaient semées pour tester la viabilité et dormance des graines. Les résultats indiquent l'existence d'une dispersion par déhiscence explosive; seulement 35% des graines tombent au-dessous de la plante, et le reste dans les alentours; quelques-unes atteignent des distances supérieures à 3 m. L'index de dormition est de 98.9%

    Spread of the alien bleak Alburnus alburnus (Linnaeus, 1758) (Actinopterygii, Cyprinidae) in the Iberian Peninsula: the role of reservoirs

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    Desde su aparición en un afluente de la cuenca del Ebro en 1992, el alburno Alburnus alburnus se ha expandido en gran parte de la península Ibérica. El presente trabajo aporta nueva información sobre su expansión (basada en el muestreo de 598 localidades mediante pesca eléctrica). Se facilita información detallada sobre su actual distribución en la cuenca del Ebro y en cuencas al este de los Pirineos, así como nuevas citas de tres grandes cuencas hidrográficas. De acuerdo a su actual distribución en la península Ibérica, el alburno habita en simpatría con 15 especies endémicas (el 58% del total de endemismos ibéricos). Se analiza la posible amenaza que el alburno representa para la ictiofauna ibérica, examinando los factores causantes de su rápida expansión, en especial el papel de los embalses

    Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation

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    PM003/2016. Publisher Copyright: © 2023, The Author(s).Background: This study investigates the proteomic landscapes of chromophobe renal cell carcinoma (chRCC) and renal oncocytomas (RO), two subtypes of renal cell carcinoma that together account for approximately 10% of all renal tumors. Despite their histological similarities and shared origins, chRCC is a malignant tumor necessitating aggressive intervention, while RO, a benign growth, is often subject to overtreatment due to difficulties in accurate differentiation. Methods: We conducted a label-free quantitative proteomic analysis on solid biopsies of chRCC (n = 5), RO (n = 5), and normal adjacent tissue (NAT, n = 5). The quantitative analysis was carried out by comparing protein abundances between tumor and NAT specimens. Our analysis identified a total of 1610 proteins across all samples, with 1379 (85.7%) of these proteins quantified in at least seven out of ten LC‒MS/MS runs for one renal tissue type (chRCC, RO, or NAT). Results: Our findings revealed significant similarities in the dysregulation of key metabolic pathways, including carbohydrate, lipid, and amino acid metabolism, in both chRCC and RO. Compared to NAT, both chRCC and RO showed a marked downregulation in gluconeogenesis proteins, but a significant upregulation of proteins integral to the citrate cycle. Interestingly, we observed a distinct divergence in the oxidative phosphorylation pathway, with RO showing a significant increase in the number and degree of alterations in proteins, surpassing that observed in chRCC. Conclusions: This study underscores the value of integrating high-resolution mass spectrometry protein quantification to effectively characterize and differentiate the proteomic landscapes of solid tumor biopsies diagnosed as chRCC and RO. The insights gained from this research offer valuable information for enhancing our understanding of these conditions and may aid in the development of improved diagnostic and therapeutic strategies.publishersversionepub_ahead_of_prin

    Visiones del Profesorado de Primaria sobre Materiales Didácticos Digitales

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    This article discusses the perceptions of fifth and sixth Primary school teachers about the assessment, use and training of teachers on Digital Didactic Materials (hereinafter MDD). For this purpose, semi-structured interviews have been conducted with teachers from three Autonomous Communities (Galicia, Canarias and Valencia). In this qualitative work the results show that teachers consider it necessary to use this type of resources in the classroom since they are very present in the daily life of the students. They also advocate the creation of their own materials in order to adapt them to the particular characteristics of the group-class, providing a proposal of contextualized teaching and learning. As major difficulties in the design of digital materials, teachers point to the short lifespan of MDD as they must be continuously updated, the amount of time they need to develop them as well as technical limitations to achieve an attractive, coherent and functional end resource. We are dealing with complex work, so there is a need to continue to investigate the perspectives of teachers in the creation and use of MDD in Primary Education
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