237 research outputs found
Integrating hydraulic modelling and GIS for wastewater systems management: a case study
The increasing costs related to operation and maintenance of urban wastewater systems has led to a special attention of utilities in promoting studies to address the key problem of water infiltration, inflow and improper connections entering the separate drainage networks. This is a common and hard to predict operational situation that needs to be identified and minimized as it negatively affects the managerial conditions of the network and the downstream wastewater treatment plant (WWTP) efficiency.
Management difficulties in separate drainage networks seldom occur when unexpected groundwater inflow, stormwater infiltration, and flows from improper connections enter into the dedicated sanitary sewer systems. Although the consequences that improper flows may have on wastewater systems are known, the problem is difficult to locate and quantify.
The use of modelling tools is of special relevance to the planning, management and rehabilitation of these types of systems, which can be very useful for: (i) evaluating the capacity of existing systems in real time; (ii) testing alternative solutions to solve problems detected; or testing different procedures to operate the systems in extreme events scenarios.
The implementation of mathematical models for determining the hydrodynamics behaviour of dry-weather and wet-weather flows in sewers was applied in a small urban wastewater network of the city of Braga in Portugal (Figure 1). The free user program US EPA SWMM was applied with the integration of GIS InterAqua information related to the wastewater collection system
Integrating hydraulic modelling and GIS for wastewater systems management: a case study
The increasing costs related to operation and maintenance of urban wastewater systems has led to a special attention of utilities in promoting studies to address the key problem of water infiltration, inflow and improper connections entering the separate drainage networks. This is a common and hard to predict operational situation that needs to be identified and minimized as it negatively affects the managerial conditions of the network and the downstream wastewater treatment plant efficiency. The implementation of mathematical models for determining the hydrodynamics behaviour of dry weather and wet weather flows in sewers appears to be a sound methodology to identify the causes for those adverse management conditions. This methodology was applied in a small urban wastewater network of the city of Braga (Portugal). The free user program USEPA SWMM was applied with the integration of GIS information related to the wastewater collection system
Modelling of sanitary sewer systems integrating rainfall-derived infiltration and inflow
Wastewater utilities often have management difficulties when excessive wet-weather flow leads to serious impacts in public health and environment as well as disturbing operational conditions in wastewater treatment plants (WWTP). This phenomenon, resulting from rainfall-derived infiltration and inflow (RDII), occurs mainly due to defects in pipes and manholes (infiltration) and to illicit connections from downspouts, foundation drains or cross-connections with storm sewers (inflow), contributing to sanitary sewer overflows (SSOs). These difficulties related to SSOs negatively affect: (i) the capacity and operation of sanitary sewer collection; (ii) the performance and treatment efficiency of WWTP; (iii) the risk of a public health hazards and environmental contamination.
This well-known wastewater managerial problem is very difficult to locate and quantify in practice since the needed adequate measurement equipment often entails unsustainable costs for utilities. Wastewater flow mathematical modelling integrating a digital cadastral database using Geographic Information Systems (GIS) constitutes a sound methodology in predicting sanitary sewer systems performance which is a critical issue within SSOs reduction and remediation programs.
This paper presents the implementation of a methodology based on hydroinformatic tools to determine the contribution of RDII in complex municipal sewer systems in order to establish adequate urban wastewater management policies that will effectively mitigate SSOs. USEPA SWMM, and digital cadastral database with field verification were applied in a simulation study of the small scale sanitary sewer network of Espinho (Braga, Portugal) whose results will be used in a larger scale to create a city-wide model for wastewater systems management
Modelling of Sanitary Sewer Systems integrating Rainfall-Derived Infiltration and Inflow
Municipal wastewater management difficulties may occur when excessive wet weather flow determine sanitary sewer overflows (SSOs) mainly caused by the contribution of rainfall-derived infiltration and inflow (RDII) into sanitary sewers. This excess of wet weather flow can lead to serious problems to public health and environment as well as to suboptimal operation of wastewater treatment plants. This paper presents the implementation of a methodology based on hydroinformatic tools to determine the contribution of RDII in complex municipal sewer systems in order to establish adequate urban wastewater management policies that will effectively mitigate SSOs. USEPA SWMM, and digital cadastral database with field verification were applied in a simulation study of a small scale sanitary sewer network whose results will be used in a larger scale to create a city-wide model for wastewater systems management
Postnatal depression across countries and cultures : a qualitative study
Background: Postnatal depression seems to be a universal condition with
similar rates in different countries. However, anthropologists question the
cross-cultural equivalence of depression,
particularly at a life stage so influenced by
cultural factors.
Aims: To develop a qualitative method to explore whether postnatal depression is universally recognised, attributed and
described and to enquire into people’s
perceptions of remedies and services for
morbid states of unhappiness within the
context of local services.
Method: The study took place in 15 centres in 11 countries and drew on three groups of informants: focus groups with new mothers, interviews with fathers and
grandmothers, and interviews with health
professionals.Textual analysis of these three groups was conducted separately in each centre and emergent themes compared across centres.
Results: All centres described morbid unhappiness after childbirth comparable
to postnatal depression but not all saw this
as an illness remediable by health interventions.
Conclusions: Although the findings of
this study support the universality of a
morbid state of unhappiness following childbirth, they also support concerns
about the cross-cultural equivalence of postnatal depression as an illness requiring the intervention of health professionals;
this has implications for future research
The Portuguese version of the Psychological Adjustment to Separation Test-Part A (PAST-A): a study with recently and non-recently divorced adults
Past research has demonstrated that divorced adults show more health problems and psychological distress than married adults. Considering the high prevalence rates of divorce among Western countries, new and robust measures should be developed to measure psychological distress after this specific transition in adulthood. The aim of this study was to adapt and validate a Portuguese version of the Psychological Adjustment to Separation Test-Part A (PAST-A; Sweeper and Halford in J Family Psychol 20(4):632–640, 2006). PAST-A is a self-report measure that assesses two key dimensions of separation adjustment problems: lonely-negativity and former partner attachment. Psychometric properties of the Portuguese version of PAST-A were assessed in terms of factor structure, internal consistency, and convergent and divergent validity, in an online convenience sample with divorced adults (N = 460). The PAST-A two-factor structure was confirmed by exploratory and confirmatory factor analyses, with each factor demonstrating very satisfactory internal consistency and good convergence. In terms of discriminant validity, the Portuguese PAST-A reveals a distinct factor from psychological growth after divorce. The results provided support for the use of the Portuguese PAST-A with divorced adults and also suggested that the explicative factors of the psychological adjustment to divorce may be cross-cultural stable. The non-existence of validated divorce-related well-being measures and its implications for divorce research are also discussed
Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial
BACKGROUND: The development of vaccines to control the COVID-19 pandemic progression is a worldwide priority. CoronaVac® is an inactivated SARS-CoV-2 vaccine approved for emergency use with robust efficacy and immunogenicity data reported in trials in China, Brazil, Indonesia, Turkey, and Chile. METHODS: This study is a randomized, multicenter, and controlled phase 3 trial in healthy Chilean adults aged ≥18 years. Volunteers received two doses of CoronaVac® separated by two (0-14 schedule) or four weeks (0-28 schedule). 2,302 volunteers were enrolled, 440 were part of the immunogenicity arm, and blood samples were obtained at different times. Samples from a single center are reported. Humoral immune responses were evaluated by measuring the neutralizing capacities of circulating antibodies. Cellular immune responses were assessed by ELISPOT and flow cytometry. Correlation matrixes were performed to evaluate correlations in the data measured. RESULTS: Both schedules exhibited robust neutralizing capacities with the response induced by the 0-28 schedule being better. No differences were found in the concentration of antibodies against the virus and different variants of concern between schedules. Stimulation of PBMCs with MPs induced the secretion of IFN-g and the expression of activation induced markers for both schedules. Correlation matrixes showed strong correlations between neutralizing antibodies and IFN-g secretion. CONCLUSIONS: Immunization with CoronaVac® in Chilean adults promotes robust cellular and humoral immune responses. The 0-28 schedule induced a stronger humoral immune response than the 0-14 schedule. FUNDING: Ministry of Health, Government of Chile, Confederation of Production and Commerce & Millennium Institute on Immunology and Immunotherapy, Chile. CLINICAL TRIAL NUMBER: NCT04651790
Perceptions of postnatal depression across countries and cultures: from a TransCultural Study of PostNatal Depression (TCS-PND)
Objectives
The qualitative study was conducted within the international
“Transcultural study of postnatal depression (PND)” in 17 centres
located in 13 different countries. The aim was to explore
perceptions of PND by lay and professional key informants,
specifically regarding description of symptoms, awareness of this
pathology and of possible care.
Methods
Broad areas of inquiry and open-ended probes were developed by
the TCS-PND research group during international workshops to
obtain data comparable between countries on perceptions of
PND. A non-random convenience sampling method was used to
recruit postpartum mothers for focus groups, and fathers and
grandmothers for interviews. Influential healthcare planners and
clinicians were interviewed as professional key informants in each
centre. Within sites, transcripts of focus groups and interviews
underwent a process of text analysis in the original language until
exhaustive theme extraction was achieved. Themes (in English)
from all the centres were combined into broader categories and
after consensus discussions these categories were revalidated.
Results and discussion
Qualitative data were supplemented in each centre with sociodemographic
data to address the issues of: (i) whether perceptions
of PND are related to some specific cultural perception of mental
heath and/or of status of parenthood and (ii) how high or low
levels of general care and specificity of health policy relate to
differences in perception of needs for care. Data collected using
the same probes and methodology in different countries and
cultures has enabled a comparative analysis of perceptions of
PND. In addition it has shown that, although not described with
the same words, PND is a well-recognised condition by recent
mothers in all countries in this study. Data on focus groups and
interviews from selected countries are given in the following
abstracts to illustrate some similarities and differences in
perceptions between countries
Resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents
<p>Abstract</p> <p>Background</p> <p>Recent studies have identified that a higher resting heart rate (RHR) is associated with elevated blood pressure, independent of body fatness, age and ethnicity. However, it is still unclear whether RHR can also be applied as a screening for other risk factors, such as hyperglycemia and dyslipidemia. Thus, the purpose of the presented study was to analyze the association between RHR, lipid profile and fasting glucose in obese children and adolescents.</p> <p>Methods</p> <p>The sample was composed of 180 obese children and adolescents, aged between 7-16 years. Whole-body and segmental body composition were estimated by Dual-energy X-ray absorptiometry. Resting heart rate (RHR) was measured by heart rate monitors. The fasting blood samples were analyzed for serum triglycerides, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and glucose, using the colorimetric method.</p> <p>Results</p> <p>Fasting glucose, TC, triglycerides, HDL-C, LDL-C and RHR were similar in both genders. The group of obese subjects with a higher RHR presented, at a lower age, higher triglycerides and TC. There was a significant relationship between RHR, triglycerides and TC. In the multivariate model, triglycerides and TC maintained a significant relationship with RHR independent of age, gender, general and trunk adiposity. The ROC curve indicated that RHR has a high potential for screening elevated total cholesterol and triglycerides as well as dyslipidemia.</p> <p>Conclusion</p> <p>Elevated RHR has the potential to identify subjects at an increased risk of atherosclerosis development.</p
International comparisons of behavioral and emotional problems in preschool children: parents’ reports from 24 societies
International comparisons were conducted of preschool children’s behavioral and
emotional problems as reported on the Child Behavior Checklist for Ages 1½–5 by parents
in 24 societies (N¼19,850). Item ratings were aggregated into scores on syndromes; Diagnostic
and Statistical Manual of Mental Disorders–oriented scales; a Stress Problems scale;
and Internalizing, Externalizing, and Total Problems scales. Effect sizes for scale score differences
among the 24 societies ranged from small to medium (3–12%). Although societies
differed greatly in language, culture, and other characteristics, Total Problems scores for
18 of the 24 societies were within 7.1 points of the omnicultural mean of 33.3 (on a scale of
0–198). Gender and age differences, as well as gender and age interactions with society,
were all very small (effect sizes<1%). Across all pairs of societies, correlations between
mean item ratings averaged .78, and correlations between internal consistency alphas
for the scales averaged .92, indicating that the rank orders of mean item ratings and internal
consistencies of scales were very similar across diverse societies
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