Prevalence and Associated Factors of Hypertension Among Civil Servants Working in Arba Minch Town, South Ethiopia

Despite Hypertension is a global public health challenge and a leading modifiable risk factor for cardiovascular disease and death attention was not given in developing countries. Therefore measuring the prevalence and identifying predictors of Hypertension is very important. Institution based cross sectional study design was employed from March–April, 2016 by taking 319 randomly selected civil servants working in in Arba Minch town. Data was collected using structured questionnaire and standardized instruments for physical examination by 5 trained nurses. SPSS version 20 was used for data analysis. Bi-variable and Multivariate logistic regression was employed for analysis of risk factors. The mean SBP and DBP of study participants were 120.87 + 14.15 mmHg and 80.28 + 8.8 mmHg, respectively. The prevalence of hypertension was found to be 27.8% (95% CI = 22.9-32.7%). Civil servants of age 50 years and above [AOR = 13.3], age 40-49 years [AOR = 5], age 30-39 years [AOR = 3.5], abdominal obesity [AOR=12.2], general obesity [AOR = 4.2], stress status [AOR = 12.3], current alcohol drink [AOR = 3.3], ex-drinker [AOR = 8.9] and family history of hypertension [AOR = 5.6] were found to be significantly associated with hypertension. The prevalence indicates that it is hidden epidemic in this population; therefore for screening and risk reduction program are needed

Multiple correspondence analysis as a tool for analysis of large health surveys in African settings

Background: More than two thirds of the total population of Ethiopia is estimated to be at risk of malaria. Therefore, malaria is the leading public health problem in Ethiopia.Objective: To investigate the determinants of malaria Rapid Diagnosis Test (RDT) result and the association between socio-economic, demographic and geographic factors.Method: The study used data from household cluster malaria survey which was conducted from December 2006 to January 2007. A total of 224 clusters of about 25 households each were selected from the Amhara, Oromiya and Southern Nation Nationalities and People (SNNP) regions of Ethiopia. A multiple correspondence analysis was used to jointly analyse malaria RDT result, socio-economic, demographic and geographic factors.Results: The result from multiple correspondence analysis shows that there is association between malaria RDT result and different socio-economic, demographic and geographic variables.Conclusion: There is an indication that some socio-economic, demographic and geographic factors have joint effects. It is important to confirm the association between socio-economic, demographic and geographic factors using advanced statistical techniques.Keywords: MCA, CA, malaria, RDT

A comparative study of lyophilized bovine pericardium and tunica parietalis vaginalis for repair of large abdominal wall defects in a rabbit model

The aim of this study is to investigate the effectiveness of lyophilized bovine pericardium and tunica vaginalis in repairing large abdominal wall defect in a rabbit model. Full thickness (all the layers of muscles except the skin) abdominal wall defects (3 x 4 cm) were created in 18 anaesthetized male clinically healthy New Zealand white rabbits and randomly divided into two equal group (n= 9 each). The defects of the first group were repaired with bovine pericardium, whereas the second group was with bovine tunica vaginalis parietalis. Three animals were sacrificed at 7th, 14th and 30th days of postimplantation from each group and the explanted specimens were subjected to macroscopic and microscopic examinations. The explanted grafts were replaced by newly formed collagen fibres and neo-vascularisation without any infection as well as formation of seroma. The cellular reaction was almost similar in each group. Therefore, these scaffolds can provide a structural replacement for severe and large abdominal wall defects.Key words: Lyophilized, bovine pericardium, bovine tunica vaginalis parietalis, abdominal wall defect, rabbit

Spatial and temporal patterns of deformation at the Tendaho geothermal prospect, Ethiopia

Observations of ground deformation in East Africa have been fundamental for unveiling the tectonics of continental rifting, assessing the seismic and volcanic hazard to development, and identifying geothermal resources. Here we investigate the active natural and anthropogenic processes in the Tendaho Graben, Afar using Interferometric Synthetic Aperture Radar (InSAR) collected by the Envisat satellite in 2004–2010. We used the Poly-Interferometric Rate And time series Estimation (π-RATE) method to calculate displacement in satellite line-of-sight, and a least-square inversion to decompose the line-of-sight displacement into vertical and rift perpendicular components. We observe two zones of deformation: a 20 km wide circular region of subsidence located 10 km northeast of the town of Semera with a maximum displacement rate of ∼5 cm/yr; and elongated zone (50 km) of subsidence in the area of the geothermal prospect, maximum rate of ∼4 cm/yr. The temporal characteristics of subsidence varies between these zones, with an increase in subsidence rate observed in the circular region in August 2008. We used a Bayesian inversion to find the best fitting source models and compared this to locations of seismicity and other geophysical observations. The pattern of deformation is consistent with a combination of magmatic and geothermal processes, but there does not appear to be a direct link to a sequence of dyke intrusions during 2005–2010 at Manda Hararo graben ∼60 km away, but dynamic stress changes or deep crustal flow could account for the observations

Evaluating Open Data Innovation: A Measurement Model for Digital Innovation Contests

Digital innovation contests emerge as important intermediaries in open data markets. However the understanding of how contests affect innovation value chains is low and there is a lack of innovation measurement frameworks to support the management of digital innovation contests. Therefore, in this paper we apply design science to design a measurement model for digital innovation contests from the organizer’s perspective that adds to the available knowledge of innovation measurement. We use a recent case of digital innovation contests to motivate the model and discuss its implications on the innovation value chain. The measurement model contributes with new knowledge in the area of open data innovation and provides support for practice in managing innovation through digital innovation contests. For future research we intend to enhance the model to also measure the effects on innovation ecosystems, to operationalize the measures and to evaluate the model in several digital innovation contests as well as to include the perspective of the participants

Squalene and amentoflavone from Antidesma laciniatum

Squalene, (2E, 7x,11x)-phyt-2-en-1-ol and amentoflavone have been isolated from the extract of the leaves of Antidesma laciniatum. Their structures were elucidated using spectroscopic methods. This is the first report of these compounds from Antidesma species.   KEY WORDS: Antidesma laciniatum, Euphorbiaceae, Squalene, Amentoflavone, (2E, 7x,11x)-Phyt-2-en-1-ol  Bull. Chem. Soc. Ethiop. 2006, 20(2), 325-328

Metabolic syndrome among children and adolescents in low and middle income countries: a systematic review and meta-analysis.

BackgroundMetabolic syndrome (MetS) is a clustering of cardiovascular risk factors, which is rising in the low and middle income countries (LMICs). There are various studies with inconsistent findings that are inconclusive for policy makers and program planners. Thus, this systematic review and meta-analysis aimed at estimating the pooled prevalence of MetS and its components in LMICs.MethodsElectronic searches were conducted in international databases including PubMed, Web of Science, EMBASE (Elsevier), Scopus, CINAHL (EBSCOhost), Science direct (Elsevier), Food Science and Technology Abstracts (FSTA), Global Health and Medline, and other sources (World Cat, Google Scholar, and Google). The pooled estimates were computed in the random effect model. The pooled prevalence was computed using the three diagnostic methods (IDF, ATP III and de Ferranti). Publication bias was verified using funnel plot and Egger's regression test. Subgroup and sensitivity analysis were performed to identify the possible sources of heterogeneity among the included studies.ResultIn this study, 142,142 children and adolescents from 76 eligible articles were included to compute the pooled prevalence of MetS and its components in LMCIs. MeTs among overweight and obese population was computed from 20 articles with the pooled prevalence of 24.09%, 36.5%, and 56.32% in IDF, ATP III and de Ferranti criteria, respectively. Similarly, a total of 56 articles were eligible to compute the pooled prevalence of MetS in the general population of children and adolescents. Hence, Mets was found in 3.98% (IDF), 6.71% (ATP III) and 8.91% (de Ferranti) of study subjects. Regarding the components of MetS, abdominal obesity was the major component in overweight and obese population and low HDL-C was the most common component in the general population. This study also revealed that males were highly affected by MetS than females.ConclusionThis study illustrates that MetS among children and adolescents is an emerging public health challenge in LMICs, where the prevalence of obesity is on the move. Preventive strategies such as community and school based intervention need to be designed. Promoting physical activities and healthy eating behaviors could avert this problem

Lignin biosynthesis in wheat (Triticum aestivum L.): its response to waterlogging and association with hormonal levels

Phylogenetic relationships of wheat C3H and CCoAOMT genes with the homologs from other species. Phylogenetic trees of C3H (A) and CCoAOMT (B) were generated based on nucleic acid sequence similarity of wheat genes with 15 C3H and 19 CCoAOMT genes, respectively, of other monocot and dicot species identified from the NCBI nucleotide database [39] using MEGA program [41], and the trees were inferred using Maximum Likelihood method based on the Tamura-nei model. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test of 500 replicates is shown next to the branches. ●, wheat candidate gene; ▲, genes from dicot species other than Arabidopsis; *, wheat sequence used for the analysis. (PDF 175 kb