355 research outputs found

    Assessing Berry Number for Grapevine Yield Estimation by Image Analysis: Case Study with the Red Variety β€œSyrah”

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    Mestrado em Engenharia de Viticultura e Enologia (Double degree) / Instituto Superior de Agronomia. Universidade de Lisboa / Faculdade de CiΓͺncias. Universidade do PortoThe yield estimation provides information that help growers to make decisions in order to optimize crop growth and to organize the harvest operations in field and in the cellar. In most vineyard estates yield is forecasted using manual methods. However, image analysis methods, which are less invasive low cost and more representative are now being developed. The main objective of this work was to estimate yield through data obtained in the frame of Vinbot project during the 2019 season. In this thesis, images of the grapevine variety Syrah taken in the laboratory and in the vineyards of the β€œInstituto Superior de Agronomia” in Lisbon were analyzed. In the laboratory the images were taken manually with an RGB camera, while in the field vines were imaged either manually and by the Vinbot robot. From these images, the number of visible berries were counted with MATLAB. From the laboratory values, the relationships between the number of visible berries and actual bunch weight and berry number were studied. From the data obtained in the field, it was analyzed the visibility of the berries at different levels of defoliation and the relationship between the area of visible bunches and the visible berries. Berry-by-berry occlusion showed a value of 6.4% at pea-size, 14.5% at veraison and 25% at maturation. In addition, high and significant determination coefficient were obtained between actual yield and visible berries. The comparison of estimated yield, obtained using the regression models with actual yield, showed an underestimation at all the three phonological stages. This low accuracy of the developed models show that the use of algorithms based on visible berry number on the images to estimate yield still needs further researchN/

    1995 en la evoluciΓ³n del sistema internacional

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    Assessing the EU’s commitment to multilateralism CSDP and Member States’ propensity to participate in peace missions

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    This paper analyzes the contribution of the CSDP operations to the peace building tasks of the peace operations of the global system, and examines the different levels of participation of EU Member States. Section one presents the scenario and considers the growth and expansion of practice of peace operations in the last twenty years. Section two reviews the main attributes of the CSDP operations. Section three explores the contribution of the old and new Member States to CSDP by examining the number of operations these countries participated in. The concluding section summarizes the research findings, and points to the current challenges faced by the EU’s peace missions

    Π•Π²Ρ€ΠΎΠΏΠ°, Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅ ΠΈ влияниС ΠΌΠΈΡ€ΠΎΠ²ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ

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    Since the European Union began to play a growing role in the relationships between the Member States and the Non-EU Mediterranean countries, the policymakers in Brussels have devoted a great deal of attention to devise and implement actions and programmes aimed at promoting peace, stability and growth to the area. The effects of such involvement have been not as significant as expected but not even insignificant. Tension has almost always floated over the Mediterranean waters because crises and violent conflicts have followed one another though never breaking all relations down. The present paper takes a cue from this feature of the Mediterranean area and proposes to watch the territory from a different angle of view. Contrary to the prevailing view of the Mediterranean as an area unaffected or scarcely affected by the dominant world policies, the paper analyses the impact of the world policy-making institutions and policies on the Mediterranean area. It also draws the readers’ attention towards the participation and, in significant cases, the non-participation of the governments of the area in the world institutions and policies. Accordingly, the first section highlights the concepts useful to analyze the world as the political space in which policymaking institutions have been established for building policies that respond to world-scale problems. The second section outlines the significant security and economic world policies that have been established for responding to world problems and, consequently, for bringing order to the world, the Mediterranean area included. In the third section, the focus is on forecasting the world and Mediterranean politics of the coming years by drawing the readers’ attention to the confrontation of three big powers, the USA, China and Russia. The difficulty to keep unaltered the Western coalition could not impede the renewal of the US hegemony should disorder be unsustainable to loads of countries. The Chinese model of economic openness and the non-interference of the investing companies may not work in all the Mediterranean countries. By acting as a troublemaker and game-changer in security complex settings like the Mediterranean area by bolstering authoritarian regimes, Russia mostly wants to create a situation in which the United States and the European countries find it impossible to make any decisions without its participation. Accordingly, the paper’s conclusions call for building knowledge about the reconfiguration of the world coalitions and the change of the existing order and institutions. Especially the revisionism of the three states competing for world leadership requires careful investigation. Research on the influence of such a global process on the wider Mediterranean area and the involvement of the Mediterranean countries in such a process is of paramount importance.Π‘ Ρ‚Π΅Ρ… ΠΏΠΎΡ€, ΠΊΠ°ΠΊ ЕвропСйский союз стал ΠΈΠ³Ρ€Π°Ρ‚ΡŒ Ρ€Π°ΡΡ‚ΡƒΡ‰ΡƒΡŽ Ρ€ΠΎΠ»ΡŒ Π² ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΡΡ… ΠΌΠ΅ΠΆΠ΄Ρƒ государствами-Ρ‡Π»Π΅Π½Π°ΠΌΠΈ ΠΈ срСдизСмноморскими странами, Π½Π΅ входящими Π² Π•Π‘, ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π² Π‘Ρ€ΡŽΡΡΠ΅Π»Π΅ стали ΡƒΠ΄Π΅Π»ΡΡ‚ΡŒ большоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΈ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ дСйствий ΠΈ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹Ρ… Π½Π° ΠΏΠΎΠΎΡ‰Ρ€Π΅Π½ΠΈΠ΅ ΠΌΠΈΡ€Π°, ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΈ развития Π² Ρ€Π΅Π³ΠΈΠΎΠ½Π΅. Π­Ρ„Ρ„Π΅ΠΊΡ‚ ΠΎΡ‚ Ρ‚Π°ΠΊΠΎΠ³ΠΎ участия оказался Π½Π΅ ΡΡ‚ΠΎΠ»ΡŒ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌ, ΠΊΠ°ΠΊ оТидалось, Π½ΠΎ, Ρ‚Π΅ΠΌ Π½Π΅ ΠΌΠ΅Π½Π΅Π΅, ΠΎΡ‰ΡƒΡ‚ΠΈΠΌΡ‹ΠΌ. НапряТСниС ΠΏΠΎΡ‡Ρ‚ΠΈ всСгда Π²ΠΈΡ‚Π°Π»ΠΎ Π½Π°Π΄ Π²ΠΎΠ΄Π°ΠΌΠΈ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠ³ΠΎ моря, ΠΏΠΎΡ‚ΠΎΠΌΡƒ Ρ‡Ρ‚ΠΎ кризисы ΠΈ ТСстокиС ΠΊΠΎΠ½Ρ„Π»ΠΈΠΊΡ‚Ρ‹ слСдовали ΠΎΠ΄ΠΈΠ½ Π·Π° Π΄Ρ€ΡƒΠ³ΠΈΠΌ, Π½ΠΎ Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ Ρ€Π°Π·Ρ€ΡƒΡˆΠ°Π»ΠΈ всС ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΡ. Настоящая ΡΡ‚Π°Ρ‚ΡŒΡ основана Π½Π° этой особСнности Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ ΠΈ ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅Ρ‚ Π²Π·Π³Π»ΡΠ½ΡƒΡ‚ΡŒ Π½Π° этот Ρ€Π΅Π³ΠΈΠΎΠ½ ΠΏΠΎΠ΄ Π΄Ρ€ΡƒΠ³ΠΈΠΌ ΡƒΠ³Π»ΠΎΠΌ зрСния. Π’ΠΎΠΏΡ€Π΅ΠΊΠΈ ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰Π΅ΠΌΡƒ мнСнию ΠΎ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅ ΠΊΠ°ΠΊ ΠΎ Π·ΠΎΠ½Π΅, Π½Π΅ Π·Π°Ρ‚Ρ€ΠΎΠ½ΡƒΡ‚ΠΎΠΉ ΠΈΠ»ΠΈ ΠΏΠΎΡ‡Ρ‚ΠΈ Π½Π΅ Π·Π°Ρ‚Ρ€ΠΎΠ½ΡƒΡ‚ΠΎΠΉ основными ΠΌΠΈΡ€ΠΎΠ²Ρ‹ΠΌΠΈ событиями, Π² Ρ€Π°Π±ΠΎΡ‚Π΅ анализируСтся влияниС ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹Ρ… институтов ΠΈ дСйствий, Π²Π»ΠΈΡΡŽΡ‰ΠΈΡ… Π½Π° БрСдизСмноморский Ρ€Π΅Π³ΠΈΠΎΠ½. Автор Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΡ€ΠΈΠ²Π»Π΅ΠΊΠ°Π΅Ρ‚ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Ρ‡ΠΈΡ‚Π°Ρ‚Π΅Π»Π΅ΠΉ ΠΊ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΠΉ, Π° Π² Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… случаях β€” ΠΊ пассивной ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΈ ΠΏΡ€Π°Π²ΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π² Ρ€Π΅Π³ΠΈΠΎΠ½Π° Π² ΠΌΠΈΡ€ΠΎΠ²Ρ‹Ρ… институтах ΠΈ ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅. БоотвСтствСнно, ΠΏΠ΅Ρ€Π²Ρ‹ΠΉ Ρ€Π°Π·Π΄Π΅Π» ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅Ρ‚ вниманию Ρ‡ΠΈΡ‚Π°Ρ‚Π΅Π»Π΅ΠΉ ΠΊΠΎΠ½Ρ†Π΅ΠΏΡ†ΠΈΠΈ, ΠΏΡ€ΠΈΠ³ΠΎΠ΄Π½Ρ‹Π΅ для Π°Π½Π°Π»ΠΈΠ·Π° ΠΌΠΈΡ€Π° ΠΊΠ°ΠΊ политичСского пространства, Π² ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΌ Π±Ρ‹Π»ΠΈ созданы институты для провСдСния ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ, Ρ€Π΅Π°Π³ΠΈΡ€ΡƒΡŽΡ‰Π΅ΠΉ Π½Π° ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ ΠΌΠΈΡ€ΠΎΠ²ΠΎΠ³ΠΎ ΠΌΠ°ΡΡˆΡ‚Π°Π±Π°. Π’ΠΎ Π²Ρ‚ΠΎΡ€ΠΎΠΌ Ρ€Π°Π·Π΄Π΅Π»Π΅ ΠΈΠ·Π»Π°Π³Π°ΡŽΡ‚ΡΡ основныС ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹Π΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ бСзопасности ΠΈ экономичСской ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ Π±Ρ‹Π»ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Π½Ρ‹ для рСагирования Π½Π° ΠΌΠΈΡ€ΠΎΠ²Ρ‹Π΅ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ ΠΈ, ΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ, для навСдСния порядка Π² ΠΌΠΈΡ€Π΅, Π²ΠΊΠ»ΡŽΡ‡Π°Ρ БрСдизСмноморский Ρ€Π΅Π³ΠΈΠΎΠ½. Π’ Ρ‚Ρ€Π΅Ρ‚ΡŒΠ΅ΠΌ Ρ€Π°Π·Π΄Π΅Π»Π΅ основноС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ удСляСтся ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ ΠΌΠΈΡ€ΠΎΠ²ΠΎΠΉ ΠΈ срСдизСмноморской ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π±Π»ΠΈΠΆΠ°ΠΉΡˆΠΈΡ… Π»Π΅Ρ‚ с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ противостояния Ρ‚Ρ€Π΅Ρ… Π²Π΅Π»ΠΈΠΊΠΈΡ… Π΄Π΅Ρ€ΠΆΠ°Π² β€” БША, ΠšΠΈΡ‚Π°Ρ ΠΈ России. ΠŸΡ€Π΅ΠΏΡΡ‚ΡΡ‚Π²ΠΈΡ для сохранСния Π² Π½Π΅ΠΈΠ·ΠΌΠ΅Π½Π½ΠΎΠΌ Π²ΠΈΠ΄Π΅ Π·Π°ΠΏΠ°Π΄Π½ΠΎΠΉ ΠΊΠΎΠ°Π»ΠΈΡ†ΠΈΠΈ Π½Π΅ ΠΌΠΎΠ³ΡƒΡ‚ ΠΏΠΎΠΌΠ΅ΡˆΠ°Ρ‚ΡŒ возобновлСнию Π³Π΅Π³Π΅ΠΌΠΎΠ½ΠΈΠΈ БША, Ссли бСспорядок окаТСтся Π½Π΅ΠΏΡ€ΠΈΠ΅ΠΌΠ»Π΅ΠΌΡ‹ΠΌ для большого числа стран. ΠšΠΈΡ‚Π°ΠΉΡΠΊΠ°Ρ модСль экономичСской открытости ΠΈ Π½Π΅ΠΉΡ‚Ρ€Π°Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ-инвСсторов ΠΌΠΎΠΆΠ΅Ρ‚ Ρ€Π°Π±ΠΎΡ‚Π°Ρ‚ΡŒ Π½Π΅ Π²ΠΎ всСх странах Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ. ΠΠ°Ρ€ΡƒΡˆΠ°Ρ спокойствиС ΠΈ измСняя ΠΏΡ€Π°Π²ΠΈΠ»Π° ΠΈΠ³Ρ€Ρ‹ Π² слоТных условиях бСзопасности, Ρ‚Π°ΠΊΠΈΡ… ΠΊΠ°ΠΊ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅, поддСрТивая Π°Π²Ρ‚ΠΎΡ€ΠΈΡ‚Π°Ρ€Π½Ρ‹Π΅ Ρ€Π΅ΠΆΠΈΠΌΡ‹, Россия стрСмится ΡΠΎΠ·Π΄Π°Ρ‚ΡŒ ΡΠΈΡ‚ΡƒΠ°Ρ†ΠΈΡŽ, Π² ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΉ Π‘ΠΎΠ΅Π΄ΠΈΠ½Π΅Π½Π½Ρ‹Π΅ Π¨Ρ‚Π°Ρ‚Ρ‹ АмСрики ΠΈ СвропСйскиС страны Π½Π΅ ΠΌΠΎΠ³Π»ΠΈ Π±Ρ‹ ΠΏΡ€ΠΈΠ½ΠΈΠΌΠ°Ρ‚ΡŒ Π½ΠΈΠΊΠ°ΠΊΠΈΡ… Ρ€Π΅ΡˆΠ΅Π½ΠΈΠΉ Π±Π΅Π· Π΅Π΅ участия. БоотвСтствСнно, Π²Ρ‹Π²ΠΎΠ΄Ρ‹ ΡΡ‚Π°Ρ‚ΡŒΠΈ ΠΏΡ€ΠΈΠ·Ρ‹Π²Π°ΡŽΡ‚ ΠΊ накоплСнию Π·Π½Π°Π½ΠΈΠΉ ΠΎ Ρ€Π΅ΠΊΠΎΠ½Ρ„ΠΈΠ³ΡƒΡ€Π°Ρ†ΠΈΠΈ ΠΌΠΈΡ€ΠΎΠ²Ρ‹Ρ… ΠΊΠΎΠ°Π»ΠΈΡ†ΠΈΠΉ ΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½ΠΎΠ³ΠΎ полоТСния. ОсобСнно Ρ‚Ρ‰Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ слСдуСт ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΡƒ Ρ€Π΅Π²ΠΈΠ·ΠΈΠΎΠ½ΠΈΠ·ΠΌΠ° Ρ‚Ρ€Π΅Ρ… государств, ΡΠΎΡ€Π΅Π²Π½ΡƒΡŽΡ‰ΠΈΡ…ΡΡ Π·Π° ΠΌΠΈΡ€ΠΎΠ²ΠΎΠ΅ лидСрство. ΠŸΠ΅Ρ€Π²ΠΎΡΡ‚Π΅ΠΏΠ΅Π½Π½ΠΎΠ΅ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ ΠΈΠΌΠ΅ΡŽΡ‚ исслСдования влияния Ρ‚Π°ΠΊΠΎΠ³ΠΎ глобального процСсса Π½Π° Π±ΠΎΠ»Π΅Π΅ ΠΎΠ±ΡˆΠΈΡ€Π½Ρ‹ΠΉ Ρ€Π°ΠΉΠΎΠ½ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ ΠΈ Π½Π° участиС срСдизСмноморских стран Π² этом процСссС

    Changes in germination and glyoxylate and respiratory enzymes of Pinus pinea seeds under various abiotic stresses

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    Abstract This study examined Pinus pinea seeds for their tolerance to osmotic potentials of βˆ’0.30MPa (10% polyethylene glycol [PEG]), βˆ’0.58MPa (18% PEG), βˆ’0.80MPa (21% PEG), βˆ’1.05MPa (24% PEG), pH values of 4, 5, 6, 7, 8, 9, 10, and different calcareous solutions (5, 10, 20 and 40% CaCO3). The main enzymes of glyoxylate cycle and respiratory pathway were tested. Pinus pinea seeds under no stressful condition (Control) and 5% CaCO3 reached 100% of germination. Higher concentrations of CaCO3 (20, 40%) and lower pH (4–5) adversely affected seed germination percentage, glyoxylic and respiratory enzyme activities. PEG caused the most detrimental effects on Pinus seeds; increasing the osmotic potential the germination was completely inhibited. These results suggest that Pinus pinea is able to germinate in calcareous and alkaline soils rather than in soils with lower water availability and acidic conditions

    Inhibition of phosphodiesterase type 5 and exercise in arterial hypertension

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    Hypertensive patients exhibit impaired exercise capacity, a strong independent risk factor for cardiovascular disease, and the mechanisms responsible for this are not fully determined. Potential candidates may include endothelial vasomotor dysfunction and arterial stiffness, both of which are associated with hypertension. Impairment of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway plays a major role in the development of these abnormalities, suggesting that enhancement of NO-cGMP signalling through phosphodiesterase type 5 (PDE5) inhibition may offer therapeutic potential in arterial hypertension. This thesis investigated the effects of the PDE5 inhibitor sildenafil citrate on exercise-induced vasodilatation, maximal exercise capacity and arterial stiffness in hypertensive patients, using different studies involving local limb and whole body exercise. Preliminary dose-ranging studies were initially performed to investigate the intraarterial (brachial) effects of sildenafil on forearm blood flow (FBF), and to select an appropriate, cGMP-independent, vasodilator to use as a control. On the basis on these studies, it was established that sildenafil, infused at 50ΞΌg/min, and verapamil, infused at 5ΞΌg/min, had similar vasodilator effect on FBF. Ten untreated hypertensive patients and ten matched normotensive subjects were then studied in a three-way, randomised, single-blind and placebo-controlled FBF study. The aim was to investigate the effects of sildenafil on handgrip exercise-induced vasodilatation, and to compare this response with verapamil and saline (placebo). Preinfusion exercise-induced vasodilatation was significantly reduced in hypertensive compared with normotensive subjects (P<0.001). However, after the infusions, while verapamil did not affect the vasodilator response to exercise in either group, sildenafil substantially enhanced this response in hypertensive patients, but not in normotensive subjects (P<0.05). These results suggested that sildenafil, through an increase in cGMP levels in the vasculature, substantially and selectively improves the vasodilator response to handgrip exercise in hypertensive patients

    Π•Π²Ρ€ΠΎΠΏΠ°, Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅ ΠΈ влияниС ΠΌΠΈΡ€ΠΎΠ²ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ

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    Π ΡƒΠΊΠΎΠΏΠΈΡΡŒ поступила Π² Ρ€Π΅Π΄Π°ΠΊΡ†ΠΈΡŽ: 28.03.2021. ΠŸΡ€ΠΈΠ½ΡΡ‚Π° ΠΊ ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΈ: 11.05.2021.Received: 28.03.2021. Accepted: 11.05.2021.Π‘ Ρ‚Π΅Ρ… ΠΏΠΎΡ€, ΠΊΠ°ΠΊ ЕвропСйский союз стал ΠΈΠ³Ρ€Π°Ρ‚ΡŒ Ρ€Π°ΡΡ‚ΡƒΡ‰ΡƒΡŽ Ρ€ΠΎΠ»ΡŒ Π² ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΡΡ… ΠΌΠ΅ΠΆΠ΄Ρƒ государствами-Ρ‡Π»Π΅Π½Π°ΠΌΠΈ ΠΈ срСдизСмноморскими странами, Π½Π΅ входящими Π² Π•Π‘, ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π² Π‘Ρ€ΡŽΡΡΠ΅Π»Π΅ стали ΡƒΠ΄Π΅Π»ΡΡ‚ΡŒ большоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΈ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ дСйствий ΠΈ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹Ρ… Π½Π° ΠΏΠΎΠΎΡ‰Ρ€Π΅Π½ΠΈΠ΅ ΠΌΠΈΡ€Π°, ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΈ развития Π² Ρ€Π΅Π³ΠΈΠΎΠ½Π΅. Π­Ρ„Ρ„Π΅ΠΊΡ‚ ΠΎΡ‚ Ρ‚Π°ΠΊΠΎΠ³ΠΎ участия оказался Π½Π΅ ΡΡ‚ΠΎΠ»ΡŒ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌ, ΠΊΠ°ΠΊ оТидалось, Π½ΠΎ, Ρ‚Π΅ΠΌ Π½Π΅ ΠΌΠ΅Π½Π΅Π΅, ΠΎΡ‰ΡƒΡ‚ΠΈΠΌΡ‹ΠΌ. НапряТСниС ΠΏΠΎΡ‡Ρ‚ΠΈ всСгда Π²ΠΈΡ‚Π°Π»ΠΎ Π½Π°Π΄ Π²ΠΎΠ΄Π°ΠΌΠΈ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠ³ΠΎ моря, ΠΏΠΎΡ‚ΠΎΠΌΡƒ Ρ‡Ρ‚ΠΎ кризисы ΠΈ ТСстокиС ΠΊΠΎΠ½Ρ„Π»ΠΈΠΊΡ‚Ρ‹ слСдовали ΠΎΠ΄ΠΈΠ½ Π·Π° Π΄Ρ€ΡƒΠ³ΠΈΠΌ, Π½ΠΎ Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ Ρ€Π°Π·Ρ€ΡƒΡˆΠ°Π»ΠΈ всС ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΡ. Настоящая ΡΡ‚Π°Ρ‚ΡŒΡ основана Π½Π° этой особСнности Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ ΠΈ ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅Ρ‚ Π²Π·Π³Π»ΡΠ½ΡƒΡ‚ΡŒ Π½Π° этот Ρ€Π΅Π³ΠΈΠΎΠ½ ΠΏΠΎΠ΄ Π΄Ρ€ΡƒΠ³ΠΈΠΌ ΡƒΠ³Π»ΠΎΠΌ зрСния. Π’ΠΎΠΏΡ€Π΅ΠΊΠΈ ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰Π΅ΠΌΡƒ мнСнию ΠΎ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅ ΠΊΠ°ΠΊ ΠΎ Π·ΠΎΠ½Π΅, Π½Π΅ Π·Π°Ρ‚Ρ€ΠΎΠ½ΡƒΡ‚ΠΎΠΉ ΠΈΠ»ΠΈ ΠΏΠΎΡ‡Ρ‚ΠΈ Π½Π΅ Π·Π°Ρ‚Ρ€ΠΎΠ½ΡƒΡ‚ΠΎΠΉ основными ΠΌΠΈΡ€ΠΎΠ²Ρ‹ΠΌΠΈ событиями, Π² Ρ€Π°Π±ΠΎΡ‚Π΅ анализируСтся влияниС ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹Ρ… институтов ΠΈ дСйствий, Π²Π»ΠΈΡΡŽΡ‰ΠΈΡ… Π½Π° БрСдизСмноморский Ρ€Π΅Π³ΠΈΠΎΠ½. Автор Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΡ€ΠΈΠ²Π»Π΅ΠΊΠ°Π΅Ρ‚ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Ρ‡ΠΈΡ‚Π°Ρ‚Π΅Π»Π΅ΠΉ ΠΊ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΠΉ, Π° Π² Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… случаях β€” ΠΊ пассивной ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΈ ΠΏΡ€Π°Π²ΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π² Ρ€Π΅Π³ΠΈΠΎΠ½Π° Π² ΠΌΠΈΡ€ΠΎΠ²Ρ‹Ρ… институтах ΠΈ ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅. БоотвСтствСнно, ΠΏΠ΅Ρ€Π²Ρ‹ΠΉ Ρ€Π°Π·Π΄Π΅Π» ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅Ρ‚ вниманию Ρ‡ΠΈΡ‚Π°Ρ‚Π΅Π»Π΅ΠΉ ΠΊΠΎΠ½Ρ†Π΅ΠΏΡ†ΠΈΠΈ, ΠΏΡ€ΠΈΠ³ΠΎΠ΄Π½Ρ‹Π΅ для Π°Π½Π°Π»ΠΈΠ·Π° ΠΌΠΈΡ€Π° ΠΊΠ°ΠΊ политичСского пространства, Π² ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΌ Π±Ρ‹Π»ΠΈ созданы институты для провСдСния ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ, Ρ€Π΅Π°Π³ΠΈΡ€ΡƒΡŽΡ‰Π΅ΠΉ Π½Π° ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ ΠΌΠΈΡ€ΠΎΠ²ΠΎΠ³ΠΎ ΠΌΠ°ΡΡˆΡ‚Π°Π±Π°. Π’ΠΎ Π²Ρ‚ΠΎΡ€ΠΎΠΌ Ρ€Π°Π·Π΄Π΅Π»Π΅ ΠΈΠ·Π»Π°Π³Π°ΡŽΡ‚ΡΡ основныС ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹Π΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ бСзопасности ΠΈ экономичСской ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ Π±Ρ‹Π»ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Π½Ρ‹ для рСагирования Π½Π° ΠΌΠΈΡ€ΠΎΠ²Ρ‹Π΅ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ ΠΈ, ΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ, для навСдСния порядка Π² ΠΌΠΈΡ€Π΅, Π²ΠΊΠ»ΡŽΡ‡Π°Ρ БрСдизСмноморский Ρ€Π΅Π³ΠΈΠΎΠ½. Π’ Ρ‚Ρ€Π΅Ρ‚ΡŒΠ΅ΠΌ Ρ€Π°Π·Π΄Π΅Π»Π΅ основноС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ удСляСтся ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ ΠΌΠΈΡ€ΠΎΠ²ΠΎΠΉ ΠΈ срСдизСмноморской ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π±Π»ΠΈΠΆΠ°ΠΉΡˆΠΈΡ… Π»Π΅Ρ‚ с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ противостояния Ρ‚Ρ€Π΅Ρ… Π²Π΅Π»ΠΈΠΊΠΈΡ… Π΄Π΅Ρ€ΠΆΠ°Π² β€” БША, ΠšΠΈΡ‚Π°Ρ ΠΈ России. ΠŸΡ€Π΅ΠΏΡΡ‚ΡΡ‚Π²ΠΈΡ для сохранСния Π² Π½Π΅ΠΈΠ·ΠΌΠ΅Π½Π½ΠΎΠΌ Π²ΠΈΠ΄Π΅ Π·Π°ΠΏΠ°Π΄Π½ΠΎΠΉ ΠΊΠΎΠ°Π»ΠΈΡ†ΠΈΠΈ Π½Π΅ ΠΌΠΎΠ³ΡƒΡ‚ ΠΏΠΎΠΌΠ΅ΡˆΠ°Ρ‚ΡŒ возобновлСнию Π³Π΅Π³Π΅ΠΌΠΎΠ½ΠΈΠΈ БША, Ссли бСспорядок окаТСтся Π½Π΅ΠΏΡ€ΠΈΠ΅ΠΌΠ»Π΅ΠΌΡ‹ΠΌ для большого числа стран. ΠšΠΈΡ‚Π°ΠΉΡΠΊΠ°Ρ модСль экономичСской открытости ΠΈ Π½Π΅ΠΉΡ‚Ρ€Π°Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ-инвСсторов ΠΌΠΎΠΆΠ΅Ρ‚ Ρ€Π°Π±ΠΎΡ‚Π°Ρ‚ΡŒ Π½Π΅ Π²ΠΎ всСх странах Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ. ΠΠ°Ρ€ΡƒΡˆΠ°Ρ спокойствиС ΠΈ измСняя ΠΏΡ€Π°Π²ΠΈΠ»Π° ΠΈΠ³Ρ€Ρ‹ Π² слоТных условиях бСзопасности, Ρ‚Π°ΠΊΠΈΡ… ΠΊΠ°ΠΊ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΠ΅, поддСрТивая Π°Π²Ρ‚ΠΎΡ€ΠΈΡ‚Π°Ρ€Π½Ρ‹Π΅ Ρ€Π΅ΠΆΠΈΠΌΡ‹, Россия стрСмится ΡΠΎΠ·Π΄Π°Ρ‚ΡŒ ΡΠΈΡ‚ΡƒΠ°Ρ†ΠΈΡŽ, Π² ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΉ Π‘ΠΎΠ΅Π΄ΠΈΠ½Π΅Π½Π½Ρ‹Π΅ Π¨Ρ‚Π°Ρ‚Ρ‹ АмСрики ΠΈ СвропСйскиС страны Π½Π΅ ΠΌΠΎΠ³Π»ΠΈ Π±Ρ‹ ΠΏΡ€ΠΈΠ½ΠΈΠΌΠ°Ρ‚ΡŒ Π½ΠΈΠΊΠ°ΠΊΠΈΡ… Ρ€Π΅ΡˆΠ΅Π½ΠΈΠΉ Π±Π΅Π· Π΅Π΅ участия. БоотвСтствСнно, Π²Ρ‹Π²ΠΎΠ΄Ρ‹ ΡΡ‚Π°Ρ‚ΡŒΠΈ ΠΏΡ€ΠΈΠ·Ρ‹Π²Π°ΡŽΡ‚ ΠΊ накоплСнию Π·Π½Π°Π½ΠΈΠΉ ΠΎ Ρ€Π΅ΠΊΠΎΠ½Ρ„ΠΈΠ³ΡƒΡ€Π°Ρ†ΠΈΠΈ ΠΌΠΈΡ€ΠΎΠ²Ρ‹Ρ… ΠΊΠΎΠ°Π»ΠΈΡ†ΠΈΠΉ ΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½ΠΎΠ³ΠΎ полоТСния. ОсобСнно Ρ‚Ρ‰Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ слСдуСт ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΡƒ Ρ€Π΅Π²ΠΈΠ·ΠΈΠΎΠ½ΠΈΠ·ΠΌΠ° Ρ‚Ρ€Π΅Ρ… государств, ΡΠΎΡ€Π΅Π²Π½ΡƒΡŽΡ‰ΠΈΡ…ΡΡ Π·Π° ΠΌΠΈΡ€ΠΎΠ²ΠΎΠ΅ лидСрство. ΠŸΠ΅Ρ€Π²ΠΎΡΡ‚Π΅ΠΏΠ΅Π½Π½ΠΎΠ΅ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ ΠΈΠΌΠ΅ΡŽΡ‚ исслСдования влияния Ρ‚Π°ΠΊΠΎΠ³ΠΎ глобального процСсса Π½Π° Π±ΠΎΠ»Π΅Π΅ ΠΎΠ±ΡˆΠΈΡ€Π½Ρ‹ΠΉ Ρ€Π°ΠΉΠΎΠ½ Π‘Ρ€Π΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡ€ΡŒΡ ΠΈ Π½Π° участиС срСдизСмноморских стран Π² этом процСссС.Since the European Union began to play a growing role in the relationships between the Member States and the Non-EU Mediterranean countries, the policymakers in Brussels have devoted a great deal of attention to devise and implement actions and programmes aimed at promoting peace, stability and growth to the area. The effects of such involvement have been not as signifi cant as expected but not even insignifi cant. Tension has almost always floated over the Mediterranean waters because crises and violent conflicts have followed one another though never breaking all relations down. The present paper takes a cue from this feature of the Mediterranean area and proposes to watch the territory from a different angle of view. Contrary to the prevailing view of the Mediterranean as an area unaffected or scarcely affected by the dominant world policies, the paper analyses the impact of the world policy-making institutions and policies on the Mediterranean area. It also draws the readers’ attention towards the participation and, in significant cases, the non-participation of the governments of the area in the world institutions and policies. Accordingly, the first section highlights the concepts useful to analyze the world as the political space in which policymaking institutions have been established for building policies that respond to world-scale problems. The second section outlines the signifi cant security and economic world policies that have been established for responding to world problems and, consequently, for bringing order to the world, the Mediterranean area included. In the third section, the focus is on forecasting the world and Mediterranean politics of the coming years by drawing the readers’ attention to the confrontation of three big powers, the USA, China and Russia. The difficulty to keep unaltered the Western coalition could not impede the renewal of the US hegemony should disorder be unsustainable to loads of countries. The Chinese model of economic openness and the non-interference of the investing companies may not work in all the Mediterranean countries. By acting as a troublemaker and game-changer in security complex settings like the Mediterranean area by bolstering authoritarian regimes, Russia mostly wants to create a situation in which the United States and the European countries find it impossible to make any decisions without its participation. Accordingly, the paper’s conclusions call for building knowledge about the reconfi guration of the world coalitions and the change of the existing order and institutions. Especially the revisionism of the three states competing for world leadership requires careful investigation. Research on the influence of such a global process on the wider Mediterranean area and the involvement of the Mediterranean countries in such a process is of paramount importance

    Nutritional status in the pediatric oncology patients

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    Nutritional status plays a vital role in the growth of children. In pediatric patients, disease-related malnutrition is a dynamic and multifactorial process supported by several factors such as inflammation, increased energy expenditure, decreased intake or reduced utilization of nutrients. In pediatric patients with malignancies, sarcopenia may coexist with malnutrition, amplifying its negative impact on prognosis. Careful monitoring of nutritional status both at diagnosis and during chemotherapy treatment allows early detection of the risk and/or presence of malnutrition. A rapid and personalized nutritional intervention can improve adherence to treatment, reduce complications and improve the patients' quality of life

    Hybrid transcatheter left ventricular reconstruction for the treatment of ischemic cardiomyopathy

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    Left ventricular (LV) enlargement is a mechanical adaptation to accommodate LV systolic inefficiency following an acute damage or a progressive functional deterioration, which fails to correct the decline of stroke volume in the long term, leading to progressive heart failure (HF). Surgical ventricular reconstruction (SVR) is a treatment for patients with severe ischemic HF aiming to restore LV efficiency by volume reduction and LV re-shaping. Recently, a new minimally-invasive hybrid technique for ventricular reconstruction has been developed by means of the Revivent (TM) system (BioVentrix Inc., San Ramon, CA, USA). The device for ventricular reconstruction consists of anchor pairs that enable plication of the anterior and free wall LV scar against the right ventricular (RV) septal scar of anteroseptal infarctions to decrease cardiac volume without ventriculotomy in a beating-heart minimally-invasive procedure, consisting of a transjugular and left thoracotomy approach. Patients with severe (Grade 4) functional mitral regurgitation (FMR) or with previous cardiac surgery procedures were excluded. Outcome of the reconstruction procedure: from 2012 until 2019, it has been applied to 203 patients, with 5 (2.5%) in-hospital deaths. LV volume reduction varied according to experience gained along years: LV end-systolic volume index decreased from baseline 43% (post-market registry) vs. 27% (CE-mark study); left ventricular ejection fraction (LVEF) increased from baseline 25% (post-market registry) vs. 16% (CE-mark study). Clinical status (NYHA class, HF questionnaire, 6-minute walking test) improved significantly compared to baseline, and re-hospitalization rate was only 13% at 6-month follow-up (60% of patients in NYHA =3). FMR grade decreased at follow-up in 63%, while it was unchanged in 37% of patients. The hybrid ventricular reconstruction (HVR) seems a promising treatment for HF patients who may benefit from LV volume reduction, with reasonable mortality and good results at follow-up. A baseline less severe clinical profile was not associated to better outcome at follow-up, which makes the procedure feasible in patients with very large ventricles and depressed ejection fraction (EF). LV reshaping has no detrimental effect on FMR, that may, on the contrary, benefit owing to less papillary muscle displacement, partial recovery of torsion dynamics and of myofibers re-orientation. A controlled study on top of optimal medical treatment is warranted to confirm its role in the management of HF patients
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