The effect of an exercise program on the health-quality of life in older adults

INTRODUCTION: An essential public health goal is to reduce age-related disabilities in the elderly. The present study aimed to investigate the effect of exercise program on health-quality of life (HQL) in older adults. METHODS: Subjects were sixty healthy adult volunteers over the age of �� years. None of the subjects had any experience in exercise programs but were physically active and able to perform activities of daily living independently. The subjects were randomly assigned into one of two groups each with �� people: test (exercise) group and control (no exercise) group. The test group was taken into a � - week aerobic exercise program. The exercises included a �- �� minute circulatory warm-up, a �� minute walking and a �-�� minute stretching/cool-down period. The exercises were performed three times per week under supervision of an experienced instructor. No exercise program was prescribed for the control group. Both groups were assessed before and after the exercise program. The LEIPAD questionnaire was used to measure HQL. RESULTS: The results showed significant improvements in all domains of the LEIPAD questionnaire whilst the level of HQL did not change and none of the scores obtained by the LEIPAD was significant. Measures of HQL improved with exercise so that there were no HQL changes in the control but significant changes were observed in the exercise group. CONCLUSION: This study suggests that an exercise program has resulted in a signific

Collection and identification of different Purslane (Portulaca oleracea L.) accessions available in Western Peninsular Malaysia

Purslane (Portulaca oleracea L.) is widely distributed around the globe and is popular as a beneficial herb in many areas of Europe, Asia, and the Mediterranean region. It is already very well known for its nutritional as well as medicinal values for both human and animal feeds. It is a rich source of potassium, magnesium, calcium and possesses the potential to be used as vegetable source of omega-3 and 6 fatty acids. It is very good source of alpha linolenic acid and gamma-linolenic acid of any green leafy vegetable. It also contains high amount of α-tocopherol and ascorbic acid. The antioxidant content and nutritional value of purslane are important for human consumption. It revealed tremendous nutritional potential and has indicated the potential use of this herb for the future. Purslane is a very fast-growing plant and can reproduce vegetatively from stem cuttings by forming adventitious roots from the cut end of the stem. Recently many plant species are threatened with extinction through human activity and the force of globalization. Plant collections are a valuable tool both in research and as a valid means of providing students at many educational levels with knowledge of and appreciation for the wonder, diversity, and beauty of plant life. Collection of diverse accessions, identification, preservation and proper management of such beneficial plants is very important for their diversity analysis which is essential for present and future human well-being. The identification of representative and manageable subset of accessions would facilitate access to the diversity available in large collections. Giving importance on the above matters a total of 45 different purslane samples were collected from different locations of Western Peninsular Malaysia, properly identified and subjected for future detailed analysis of morpho-physiological and nutritional variations among the collections

Screening of Purslane ( Portulaca oleracea

Purslane (Portulaca oleracea L.) is an herbaceous leafy vegetable crop, comparatively more salt-tolerant than any other vegetables with high antioxidants, minerals, and vitamins. Salt-tolerant crop variety development is of importance due to inadequate cultivable land and escalating salinity together with population pressure. In this view a total of 25 purslane accessions were initially selected from 45 collected purslane accessions based on better growth performance and subjected to 5 different salinity levels, that is, 0.0, 10.0, 20.0, 30.0, and 40.0 dS m−1 NaCl. Plant height, number of leaves, number of flowers, and dry matter contents in salt treated purslane accessions were significantly reduced (P≤0.05) and the enormity of reduction increased with increasing salinity stress. Based on dry matter yield reduction, among all 25 purslane accessions 2 accessions were graded as tolerant (Ac7 and Ac9), 6 accessions were moderately tolerant (Ac3, Ac5, Ac6, Ac10, Ac11, and Ac12), 5 accessions were moderately susceptible (Ac1, Ac2, Ac4, Ac8, and Ac13), and the remaining 12 accessions were susceptible to salinity stress and discarded from further study. The selected 13 purslane accessions could assist in the identification of superior genes for salt tolerance in purslane for improving its productivity and sustainable agricultural production

A Comparison of Yield Potential and Cultivar Performance of 20 Collected Purslane (Portulaca oleracea L.) Accessions Employing Seeds vs. Stem Cuttings

A glasshouse experiment was conducted in Universiti Putra Malaysia (UPM) to evaluate the regeneration and yield potential in purslane using both seeds and stem cuttings of 20 collected accessions from different locations in Western Peninsular Malaysia. Analysis results revealed significant variations (P< 0.05) for morphological traits viz., plant height, number of main branches, number of nodes, internodal distance, stem diameter, number of leaves, leaf area, number of flowers, root length, fresh and dry weight but no significant difference were observed for physiological traits viz., total chlorophyll, net photosynthesis, stomatal conductance, transpiration, water vapor deficit and for either major micro or macro minerals. Hope our research findings will eliminate the doubt of using cutting methods for purslane propagation and cultivation among producers and consumers and will promote their determination to follow purslane production in this summer at any season and anywhere. To the best of our knowledge, this is the first attempt to evaluate and to detect any significant variations arising in morphological, physiological, and especially mineral nutrition in purslane propagated through cuttings vs. through seeds

The genetic and molecular origin of natural variation for the fragrance trait in an elite Malaysian aromatic rice through quantitative trait loci mapping using SSR and gene-based markers

MRQ74, a popular aromatic Malaysian landrace, allows for charging considerably higher prices than non-aromatic landraces. Thus, breeding this profitable trait has become a priority for Malaysian rice breeding. Despite many studies on aroma genetics, ambiguities considering its genetic basis remain. It has been observed that identifying quantitative trait loci (QTLs) based on anchor markers, particularly candidate genes controlling a trait of interest, can increase the power of QTL detection. Hence, this study aimed to locate QTLs that influence natural variations in rice scent using microsatellites and candidate gene-based sequence polymorphisms. For this purpose, an F2 mapping population including 189 individual plants was developed by MRQ74 crosses with ‘MR84’, a non-scented Malaysian accession. Additionally, qualitative and quantitative approaches were applied to obtain a phenotype data framework. Consequently, we identified two QTLs on chromosomes 4 and 8. These QTLs explained from 3.2% to 39.3% of the total fragrance phenotypic variance. In addition, we could resolve linkage group 8 by adding six gene-based primers in the interval harboring the most robust QTL. Hence, we could locate a putative fgr allele in the QTL found on chromosome 8 in the interval RM223–SCU015RM (1.63 cM). The identified QTLs represent an important step toward recognition of the rice flavor genetic control mechanism. In addition, this identification will likely accelerate the progress of the use of molecular markers for gene isolation, gene-based cloning, and marker-assisted selection breeding programs aimed at improving rice cultivars

Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II is a protein, which is located at centromeres, and enzymatic topoisomerase II activity correlates with centromere activity in human cells. It is therefore possible that topoisomerase II recognizes and interacts with the alpha satellite DNA of human centromeres through an interaction with potential DNA structures formed solely at active centromeres. In the present study, human topoisomerase IIα-mediated cleavage at centromeric DNA sequences was examined in vitro. The investigation has revealed that the enzyme recognizes and cleaves a specific hairpin structure formed by alpha satellite DNA. The topoisomerase introduces a single-stranded break at the hairpin loop in a reaction, where DNA ligation is partly uncoupled from the cleavage reaction. A mutational analysis has revealed, which features of the hairpin are required for topoisomerease IIα-mediated cleavage. Based on this a model is discussed, where topoisomerase II interacts with two hairpins as a mediator of centromere cohesion

Relationship between high temperature and formation of chalkiness and their effects on quality of rice

Occurrence of chalkiness in rice is attributed to genetic and environmental factors, especially high temperature (HT). Te HT induces heat stress, which in turn compromises many grain qualities, especially transparency. Chalkiness in rice is commonly studied together with other quality traits such as amylose content, gel consistency, and protein storage. In addition to the fundamental QTLs, some other QTLs have been identifed which accelerate chalkiness occurrence under HT condition. In this review, some of the relatively stable chalkiness, amylose content, and gel consistency related QTLs have been presented well. Genetically, HT efect on chalkiness is explained by the location of certain chalkiness gene in the vicinity of high-temperature responsive genes. With regard to stable QTL distribution and availability of potential material resources, there is still feasibility to find out novel stable QTLs related to chalkiness under HT condition. A better understanding of those achievements is essential to develop new rice varieties with a reduced chalky grain percentage. Therefore, we propose the pyramiding of relatively stable and nonallelic QTLs controlling low chalkiness endosperm into adaptable rice varieties as pragmatic approach to mitigate HT effec

Heterogeneity of breast cancer risk within the South Asian female population in England: a population-based case–control study of first-generation migrants

South Asian women in England have a lower breast cancer risk than their English-native counterparts, but less is known about variations in risk between distinct South Asian ethnic subgroups. We used the data from a population-based case-control study of first-generation South Asian migrants to assess risks by ethnic subgroup. In all, 240 breast cancer cases, identified through cancer registries, were individually matched on age and general practitioner to two controls. Information on the region of origin, religious and linguistic background, and on breast cancer risk factors was obtained from participants. Breast cancer odds varied significantly between the ethnic subgroups (P=0.008), with risk increasing in the following order Bangladeshi Muslims (odds ratio (OR) 0.33, 95% confidence interval (CI): 0.10, 1.06), Punjabi Hindu (OR 0.59, 95% CI: 0.33, 1.27), Gujarati Hindu (I=reference group), Punjabi Sikh (OR 1.23, 95% CI: 0.72, 2.11) and Pakistani/Indian Muslims (OR 1.76, 95% CI: 1.10, 2.81). The statistically significant raised risk in Pakistani/Indian Muslims increased with adjustment for socioeconomic and reproductive risk factors (OR 2.12, 95% CI: 1.25, 3.58), but was attenuated, and no longer significant, with further adjustment for waist circumference and intake of nonstarch polysaccharides and fat (OR 1.49, 95% CI: 0.85, 2.63). These findings reveal differences in breast cancer risk between South Asian ethnic subgroups, which were not fully explained by reproductive differences, but were partly accounted for by diet and body size

Development of a 3D workspace Shoulder Assessment Tool Incorporating Electromyography and an Inertial Measurement Unit - A preliminary study

Traditional shoulder Range of Movement (ROM) measurement tools suffer from inaccuracy or from long experimental set-up times. Recently, it has been demonstrated that relatively low-cost wearable inertial measurement unit (IMU) sensors can overcome many of the limitations of traditional motion tracking systems. The aim of this study is to develop and evaluate a single IMU combined with an Electromyography (EMG) sensor to monitor the 3D reachable workspace with simultaneous measurement of deltoid muscle activity across the shoulder ROM. Six volunteer subjects with healthy shoulders and one participant with a ‘frozen’ shoulder were recruited to the study. Arm movement in 3D space was plotted in spherical coordinates while the relative EMG intensity of any arm position is presented graphically. The results showed that there was an average ROM surface area of 27291±538 deg2 among all six healthy individuals and a ROM surface area of 13571±308 deg2 for the subject with frozen shoulder. All three sections of the deltoid show greater EMG activity at higher elevation angles. Using such tools enables individuals, surgeons and physiotherapists to measure the maximum envelope of motion in conjunction with muscle activity in order to provide an objective assessment of shoulder performance in the voluntary 3D workspace