Coherence properties of light propagated through a scattering medium

Partially-coherent, quasi-monochromatic optical fields are fully described by their Mutual Optical Intensity (MOI) or the phase-space equivalent, the Generalised Radiance (GR). This paper reports on the application of a propagation-based phase-space tomographic technique for determining both the MOI and the GR of wavefields. This method is applied to the reconstruction of the MOI and the GR of an optical wavefield propagated through a suspension of \~10micrometre diameter polystyrene spheres.Comment: Photonics 2004, 7th International conference on optoelectronics, fibre optics and photonics, Kochi, Indi

Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

Background Results of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these effects. Methods FOCUS was a pragmatic, multicentre, parallel group, double-blind, randomised, placebo-controlled trial done at 103 hospitals in the UK. Patients were eligible if they were aged 18 years or older, had a clinical stroke diagnosis, were enrolled and randomly assigned between 2 days and 15 days after onset, and had focal neurological deficits. Patients were randomly allocated fluoxetine 20 mg or matching placebo orally once daily for 6 months via a web-based system by use of a minimisation algorithm. The primary outcome was functional status, measured with the modified Rankin Scale (mRS), at 6 months. Patients, carers, health-care staff, and the trial team were masked to treatment allocation. Functional status was assessed at 6 months and 12 months after randomisation. Patients were analysed according to their treatment allocation. This trial is registered with the ISRCTN registry, number ISRCTN83290762. Findings Between Sept 10, 2012, and March 31, 2017, 3127 patients were recruited. 1564 patients were allocated fluoxetine and 1563 allocated placebo. mRS data at 6 months were available for 1553 (99·3%) patients in each treatment group. The distribution across mRS categories at 6 months was similar in the fluoxetine and placebo groups (common odds ratio adjusted for minimisation variables 0·951 [95% CI 0·839–1·079]; p=0·439). Patients allocated fluoxetine were less likely than those allocated placebo to develop new depression by 6 months (210 [13·43%] patients vs 269 [17·21%]; difference 3·78% [95% CI 1·26–6·30]; p=0·0033), but they had more bone fractures (45 [2·88%] vs 23 [1·47%]; difference 1·41% [95% CI 0·38–2·43]; p=0·0070). There were no significant differences in any other event at 6 or 12 months. Interpretation Fluoxetine 20 mg given daily for 6 months after acute stroke does not seem to improve functional outcomes. Although the treatment reduced the occurrence of depression, it increased the frequency of bone fractures. These results do not support the routine use of fluoxetine either for the prevention of post-stroke depression or to promote recovery of function. Funding UK Stroke Association and NIHR Health Technology Assessment Programme

Noninterferometric characterization of partially coherent scalar wave fields and application to scattered light.

We report on the application of a simple propagation-based phase-space tomographic technique to the determination of characteristic projections through the mutual optical intensity and the generalized radiance of a scalar, quasi-monochromatic partially coherent wave field. This method is applied to the reconstruction of the coherence functions of an initially spatially coherent optical wave field that has propagated through a suspension of polystyrene microspheres. As anticipated, we see that the field separates into a ballistic, or unscattered, component and a scattered component with a much shorter coherence length. Good agreement is obtained between experimental results and the results of a model based on a wave-transport equation

Hybrid Evolutionary Algorithms: Methodologies, Architectures, and Reviews

Evolutionary computation has become an important problem solving methodology among many researchers. The population-based collective learning process, self-adaptation, and robustness are some of the key features of evolutionary algorithms when compared to other global optimization techniques. Even though evolutionary computation has been widely accepted for solving several important practical applications in engineering, business, commerce, etc., yet in practice sometimes they deliver only marginal performance. Inappropriate selection of various parameters, representation, etc. are frequently blamed. There is little reason to expect that one can find a uniformly best algorithm for solving all optimization problems. This is in accordance with the No Free Lunch theorem, which explains that for any algorithm, any elevated performance over one class of problems is exactly paid for in performance over another class. Evolutionary algorithm behavior is determined by the exploitation and exploration relationship kept throughout the run. All these clearly illustrates the need for hybrid evolutionary approaches where the main task is to optimize the performance of the direct evolutionary approach. Recently, hybridization of evolutionary algorithms is getting popular due to their capabilities in handling several real world problems involving complexity, noisy environment, imprecision, uncertainty, and vagueness. In this chapter, first we emphasize the need for hybrid evolutionary algorithms and then we illustrate the various possibilities for hybridization of an evolutionary algorithm and also present some of the generic hybrid evolutionary architectures that has evolved during the last couple of decades. We also provide a review of some of the interesting hybrid frameworks reported in the literature