924 research outputs found

    Design of an Electric Propulsion System for SCEPTOR

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    The rise of electric propulsion systems has pushed aircraft designers towards new and potentially transformative concepts. As part of this effort, NASA is leading the SCEPTOR program which aims at designing a fully electric distributed propulsion general aviation aircraft. This article highlights critical aspects of the design of SCEPTOR's propulsion system conceived at Joby Aviation in partnership with NASA, including motor electromagnetic design and optimization as well as cooling system integration. The motor is designed with a finite element based multi-objective optimization approach. This provides insight into important design tradeoffs such as mass versus efficiency, and enables a detailed quantitative comparison between different motor topologies. Secondly, a complete design and Computational Fluid Dynamics analysis of the air breathing cooling system is presented. The cooling system is fully integrated into the nacelle, contains little to no moving parts and only incurs a small drag penalty. Several concepts are considered and compared over a range of operating conditions. The study presents trade-offs between various parameters such as cooling efficiency, drag, mechanical simplicity and robustness

    The 4-(3-chloro-4-methyl­phen­yl)-1,2,3,5-dithia­diazol-3-yl radical

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    The asymmetric unit of the title compound, C8H6ClN2S2, comprises two mol­ecules forming a dimer via π–π stacking inter­actions [centroid–centroid distance = 3.634 (10) Å] and intra­dimer S⋯S contacts [3.012 (4) and 3.158 (4) Å] between the two mol­ecules in a cis-antarafacial arrangement

    The impact of cave lighting on the bioluminescent display of the Tasmanian glow-worm Arachnocampa tasmaniensis

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    Bioluminescent larvae of the dipteran genus Arachnocampa are charismatic microfauna that can reach high densities in caves, where they attract many visitors. These focal populations are the subjects of conservation management because of their high natural and commercial value. Despite their tourism importance, little is known about their susceptibility and resilience to natural or human impacts. At Marakoopa Cave in northern Tasmania, guided tours take visitors through different chambers and terminate at a viewing platform where the cave lighting is extinguished and a glowing colony of Arachnocampa tasmaniensis (Diptera: Keroplatidae) larvae on the chamber ceiling is revealed. Research has shown that exposure to artificial light can cause larvae to douse or dim their bioluminescence; hence, the cave lighting associated with visitor access could reduce the intensity of the natural display. We used time-lapse digital photography to record light output over 10 days to determine whether cave lighting affects the intensity or rhythmicity of bioluminescence. Simultaneously, another colony in a different section of the cave, away from tourist activity, was photographed over 3 days. Both colonies showed high-amplitude 24 h cycling of bioluminescence intensity, with the peak occurring at 11.50 h at the unvisited site and 12.50 h at the main chamber, so the time of peak display did not appear to be substantially affected by light exposure. Intermittent light exposure experienced by larvae in the main chamber caused detectable reductions in bioluminescence intensity; however, recovery was rapid and the overall shape of the daily bioluminescence curve closely matched that of the unvisited colony. In conclusion, the artificial light exposure regime used in Marakoopa Cave does not have a substantial effect on the timing or quality of the bioluminescence display. The time-lapse photographic monitoring method could be permanently implemented at focal tourism sites to provide information about daily, seasonal and annual fluctuations in the displays, the response to events such as drought and flood, and the population's ability to recover from adverse conditions

    Fanny Copeland and the geographical imagination

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    Raised in Scotland, married and divorced in the English south, an adopted Slovene, Fanny Copeland (1872 – 1970) occupied the intersection of a number of complex spatial and temporal conjunctures. A Slavophile, she played a part in the formation of what subsequently became the Kingdom of Yugoslavia that emerged from the First World War. Living in Ljubljana, she facilitated the first ‘foreign visit’ (in 1932) of the newly formed Le Play Society (a precursor of the Institute of British Geographers) and guided its studies of Solčava (a then ‘remote’ Alpine valley system) which, led by Dudley Stamp and commended by Halford Mackinder, were subsequently hailed as a model for regional studies elsewhere. Arrested by the Gestapo and interned in Italy during the Second World War, she eventually returned to a socialist Yugoslavia, a celebrated figure. An accomplished musician, linguist, and mountaineer, she became an authority on (and populist for) the Julian Alps and was instrumental in the establishment of the Triglav National Park. Copeland’s role as participant observer (and protagonist) enriches our understanding of the particularities of her time and place and illuminates some inter-war relationships within G/geography, inside and outside the academy, suggesting their relative autonomy in the production of geographical knowledge

    Police views of suicidal persons and the law criminalizing attempted suicide in Ghana: A qualitative study with policy implications

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    The penal code of Ghana condemns suicide attempt. The present study sought to explore the views of the police on persons who attempt suicide and the law criminalizing the act. Qualitative in-depth interviews were used to explore the views of 18 officers of the Ghana Police Service. Data were analyzed using thematic analysis technique. Findings showed that the police officers profiled suicide attempters as needy, enigmatic, ignorant, and blameworthy. Majority (n = 14) of them disagreed with the law and suggested a repeal, whereas only four of them agreed with the law. Regardless of their positions on criminalization, they showed an inclination to help, rather than arrest, when confronted with such persons in line of their duty. Educating the police on suicidal behavior may help to deepen their understanding and help improve the way they handle suicidal persons. This may also strengthen police suicide prevention gatekeeping obligations

    High variety of known and new RNA and DNA viruses of diverse origins in untreated sewage

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    Deep sequencing of untreated sewage provides an opportunity to monitor enteric infections in large populations and for high-throughput viral discovery. A metagenomics analysis of purified viral particles in untreated sewage from the United States (San Francisco, CA), Nigeria (Maiduguri), Thailand (Bangkok), and Nepal (Kathmandu) revealed sequences related to 29 eukaryotic viral families infecting vertebrates, invertebrates, and plants (BLASTx E score, <10(−4)), including known pathogens (>90% protein identities) in numerous viral families infecting humans (Adenoviridae, Astroviridae, Caliciviridae, Hepeviridae, Parvoviridae, Picornaviridae, Picobirnaviridae, and Reoviridae), plants (Alphaflexiviridae, Betaflexiviridae, Partitiviridae, Sobemovirus, Secoviridae, Tombusviridae, Tymoviridae, Virgaviridae), and insects (Dicistroviridae, Nodaviridae, and Parvoviridae). The full and partial genomes of a novel kobuvirus, salivirus, and sapovirus are described. A novel astrovirus (casa astrovirus) basal to those infecting mammals and birds, potentially representing a third astrovirus genus, was partially characterized. Potential new genera and families of viruses distantly related to members of the single-stranded RNA picorna-like virus superfamily were genetically characterized and named Picalivirus, Secalivirus, Hepelivirus, Nedicistrovirus, Cadicistrovirus, and Niflavirus. Phylogenetic analysis placed these highly divergent genomes near the root of the picorna-like virus superfamily, with possible vertebrate, plant, or arthropod hosts inferred from nucleotide composition analysis. Circular DNA genomes distantly related to the plant-infecting Geminiviridae family were named Baminivirus, Nimivirus, and Niminivirus. These results highlight the utility of analyzing sewage to monitor shedding of viral pathogens and the high viral diversity found in this common pollutant and provide genetic information to facilitate future studies of these newly characterized viruses

    The vertical plate in laminar free convection: Effects of leading and trailing edges and discontinuous temperature

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    For laminar free-convection flow past a heated vertical plate of finite length, the local asymptotic flow structure is studied in regions where the boundary-layer equations do not provide a correct approximation at large Grashof numbers. The leading-edge region is shown to contribute a secondorder term to the integrated heat transfer. An integral form of the energy equation permits calculation of this correction in terms of the second-order boundary-layer solution away from the edge, without knowledge of the flow details near the edge, which can be obtained only by solution of the full Navier-Stokes equations. Near the trailing edge and near a jump in the prescribed plate temperature the longitudinal pressure gradient is found to be important in a thin sublayer adjacent to the plate, and the transverse pressure gradient is important in the remainder of the boundary layer, each for a distance along the plate which is slightly larger in order of magnitude than the boundary-layer thickness. At the trailing edge the sublayer problem is nonlinear and cannot be solved analytically, but it can be shown that the local correction to the total heat transfer is of slightly larger order of magnitude than the leading-edge correction. It is pointed out that the trailing-edge flow is identical in form to the flow near the edge of a rotating disc in a stationary fluid. The temperature-jump problem is linear and a solution is given which shows how the singularity in streamline slope predicted by the boundary-layer solution is removed. Bei laminarer natĂŒrlicher Strömung lĂ€ngs einer senkrecht stehenden endlichen geheizten Platte bei sehr grossen Grashof'schen Zahlen gibt es kleine Bereiche, bei denen die Grenzschichtgleichungen keine echte asymptotische Darstellung liefern. Im Vorderkantenbereich findet man ein Zusatzglied zweiter Ordnung fĂŒr die gesamte WĂ€rmeĂŒbertragung. Die Berechnung dieser Korrektur erfolgt durch eine Integralform der Energiegleichung, wobei nur die Lösung der Grenzschichtgleichung zweiter Ordnung fern von der Kante benĂŒtzt wird, wĂ€hrend die Kenntnis der Strömung in der NĂ€he der Kante nur durch eine Lösung der exakten Navier-Stokes'schen Gleichungen gefunden werden könnte. In der NĂ€he der Hinterkante und in der NĂ€he einer DiskontinuitĂ€t der gegebenen Plattentemperatur wird das LĂ€ngsdruckgefĂ€lle in einer dĂŒnnen Unterschicht wichtig; das QuerdruckgefĂ€lle wird in dem restlichen Teil der Grenzschicht berĂŒcksichtigt, fĂŒr eine LĂ€nge, deren Grössenordnung etwas grösser ist, als die der Grenzschichtdicke. Bei der Hinterkante ist das Unterschichtsproblem nicht linear, und es gibt keine analytische Lösung, aber man kann zeigen, dass die Grössenordnung der Korrektur der gesamten WĂ€rmeĂŒbertragung etwas grösser ist als die Korrektur bei der Vorderkante. Die Strömung bei der Hinterkante ist dieselbe wie die Strömung bei der Kante einer rotierenden Scheibe in einer sonst ruhenden FlĂŒssigkeit. Das Temperatur-DiskontinuitĂ€tsproblem ist linear, und eine Lösung ist hier gefunden worden, wodurch die von der Grenzschichttheorie gegebene SingularitĂ€t (unendliche Quergeschwindigkeit) entfernt wird.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43360/1/33_2005_Article_BF01591175.pd

    Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer

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    <p>Abstract</p> <p>Background</p> <p>Accelerated partial breast irradiation (APBI) may be used to deliver radiation to the tumor bed post-lumpectomy in eligible patients with breast cancer. Patient and tumor characteristics as well as the lumpectomy technique can influence patient eligibility for APBI. This report describes a lumpectomy procedure and examines patient, tumor, and surgical characteristics from a prospective, multicenter study of electronic brachytherapy.</p> <p>Methods</p> <p>The study enrolled 65 patients of age 45-84 years with ductal carcinoma or ductal carcinoma in situ, and 44 patients, who met the inclusion and exclusion criteria, were treated with APBI using the Axxent<sup>Âź </sup>electronic brachytherapy system following lumpectomy. The prescription dose was 34 Gy in 10 fractions over 5 days.</p> <p>Results</p> <p>The lumpectomy technique as described herein varied by site and patient characteristics. The balloon applicator was implanted by the surgeon (91%) or a radiation oncologist (9%) during or up to 61 days post-lumpectomy (mean 22 days). A lateral approach was most commonly used (59%) for insertion of the applicator followed by an incision site approach in 27% of cases, a medial approach in 5%, and an inferior approach in 7%. A trocar was used during applicator insertion in 27% of cases. Local anesthetic, sedation, both or neither were administered in 45%, 2%, 41% and 11% of cases, respectively, during applicator placement. The prescription dose was delivered in 42 of 44 treated patients.</p> <p>Conclusions</p> <p>Early stage breast cancer can be treated with breast conserving surgery and APBI using electronic brachytherapy. Treatment was well tolerated, and these early outcomes were similar to the early outcomes with iridium-based balloon brachytherapy.</p
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