Descomposición de la capa de hojarasca de diferentes especies perennifolias y caducifolias

Las hojarascas de las especies caducifolias y perennifolias presentan procesos diferenciales de descomposición, debidos, en gran parte, a las diferencias en su composición químic

Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

Un caso de hemangioma congénito localizado en la extremidad inferior izquierda y revisión

Vascular anomalies are common in childhood.They generally affect skin and are evident at birth or in the first weeks of life.Two main groups can be established: vascular malformations strictly speaking and hemangiomas. It is exposed a congenitalhemangioma case, located in the left lower limb, which has not undergone any involution after several months, being able topersist throughout life. Main clinical features of these disorders are also reviewed.Las anomalías vasculares congénitas son frecuentes en la infancia.Afectan generalmente a la piel y son evidentes enel momento del nacimiento o en las primeras semanas de vida. Se dividen en dos grandes grupos: las malformacio-nes vasculares propiamente dichas y los hemangiomas. Presentamos un caso de hemangioma congénito localizadoen la extremidad inferior izquierda, que al cabo de varios meses no muestra ningún signo de involución pudiendopersistir toda la vida, y se revisan las principales características clínicas de estas afecciones

Intoxicación por paracetamol: propuesta de mejora en una unidad de urgencias

Background:The paracetamol is the drug most frequently observed in pediatric poisoning, to be a frequent cause of the western world hepatotoxicity. Objective: To describe characteristics of acetaminophen poisoning, evaluate our actions in the management of this poisoning and develop a quality improvement plan. Material and methods: Observational, descriptive and retrospective study of all patients between 1 month and 15 years of age, suspected of acetaminophen poisoning, admitted in our Hospital during the period from January 1, 2002 to December 31, 2006. Results: The incidence of intoxications was 0.3% consultations, of which 40% were due to acetaminophen poisoning. 79% affected patients ingested a dose higher than 150 mg/kg, as reported by family members. In no case paracetamol blood levels reached toxic levels. Conclusions: The acetaminophen poisoning frequency is similar to that described in the literature. It is absolutely necessary to have at our disposal the paracetamol urgency levels since most of the cases are not confirmed.Thanks to this study, we have been able to assign acetaminophen urgency levels. Intestinal decontamination should not be routinely performed.The recommended antidote treatment, N-acetylcysteine, must be intravenously administered.Introducción: El paracetamol es el fármaco más frecuentemente observado en las intoxicaciones pediátricas, siendo una causa frecuente de hepatotoxicidad en el mundo occidental. Objetivo: Describir las características de las intoxicaciones por paracetamol en nuestro hospital, evaluar nuestra actuación e introducir una propuesta de mejora. Material y métodos: Estudio observacional, descriptivo, retrospectivo, de corte transversal, de pacientes ingresados en nuestro Hospital por sospecha de intoxicación por paracetamol, con edades comprendidas entre 1 mes y 15 años entre el 1 de enero de 2002 y el 31 de diciembre de 2006. Resultados: El porcentaje de consultas por intoxicación es del 0,3%, correspondiendo al paracetamol un 40%. Un 79% ingirió según refieren los familiares una dosis superior a 150 mg/kg. Los niveles de paracetamol en sangre en ningún caso alcanzaron los niveles tóxicos. Conclusiones: La frecuencia de intoxicación por paracetamol es similar a la descrita en la literatura. Es necesario disponer de los niveles de paracetamol de urgencia ya que en la mayoría de los casos no se confirma. Tras este estudio, disponemos de determinación en sangre de niveles de paracetamol en urgencias. La descontaminación intestinal no debería realizarse de forma rutinaria. El tratamiento recomendado es la N-acetilcisteína

Protocolo intoxicación por paracetamol en urgencias de pediatría del Hospital Miguel Servet

The suspicion of poisoning by acetaminophen is a frequent reason for consultation in the pediatric emergency services. Most cases will not require any action unless the administration of activated coal, but given the potential seriousness of the poisoning, it is important to determining the urgency of acetaminophen levels in blood to initiate treatment if needed antidote. In the absence of levels of urgency should start treatment until its acquisition. We present our performance protocol to patients who come to the emergency department by a suspected toxic ingestion of acetaminophen.La sospecha de intoxicación por paracetamol es un motivo frecuente de consulta en los servicios de urgencias pediátricos. La mayor parte de los casos no van a requerir ninguna actuación, salvo la administración de carbón activado, pero dada la potencial gravedad de la intoxicación, es importante la determinación de urgencia de los niveles de paracetamol en sangre para iniciar el tratamiento antidótico si fuera necesario. En caso de no disponer de los niveles de urgencia se debe iniciar el tratamiento hasta su obtención. Se presenta nuestro protocolo de actuación ante pacientes que acuden al servicio de urgencias por una sospecha de ingesta tóxica de paracetamol

Learning by educating: e-Service learning experience of oral health promotion

La metodología utilizada durante todo el proyecto fue el recurso en línea, dada la situación de crisis sanitaria debido al COVID-19. Internet fue el medio principal y único para llevar a cabo todas las actividades, desde el reclutamiento y la preparación de los estudiantes hasta la implementación del servicio y su evaluación. La realización de un e-ApS es posible y ofrece las oportunidades necesarias para que los alumnos desarrollen su valor de ciudadanía inclusiva, digna y democrática, al igual que cuando el proyecto se realiza de manera presencial.Due to the health crisis due to COVID-19, the methodology used in the project was the online resource. The Internet was the medium for carrying out all activities, from the recruitment and preparation of students to the implementation of the service and its assessment. Carrying out an e-ApS is possible and it offers the necessary opportunities for students to develop their value of inclusive, respectful and democratic citizenship, just as when the project is carried out in person.Oficina Universitaria de Aprendizaje-Servicio UCMDepto. de Especialidades Clínicas OdontológicasFac. de OdontologíaTRUEsubmitte

Italia e Spagna nel turismo del secondo dopoguerra. Società, politiche, istituzioni ed economia

Alla fine del secondo conflitto mondiale negli Stati dell'Europa occidentale avviati verso la ripresa economica, il turismo si avvantaggiò del clima di cooperazione e di pace. La cultura americana contaminò anche le pratiche turistiche e il desiderio di libertà delle società europee si espresse ben presto nella ricerca di sole e mare, spiagge, sabbia e sensualità. I saggi raccolti in questo volume aprono un nuovo fronte di ricerca nella storia del turismo euro-mediterraneo e offrono ricostruzioni, analisi e riflessioni sulle vicende di due Paesi, l'Italia e la Spagna, che tra la fine della guerra e gli anni '50 dovettero ripensare ai propri assetti istituzionali e alle proprie politiche economiche turistiche, sotto la spinta di una domanda di balneazione marina che iniziava a manifestarsi e strutturarsi, e che nei successivi anni '60 era destinata a raggiungere una dimensione massificata