Análisis de la categoría de riesgo de los ajolotes de arroyos de alta montaña (Caudata: Ambystoma)

Los ajolotes de arroyos de alta montaña (Ambystoma), forman parte de especies vulnerables debido a la naturaleza de su distribución, la cual se restringe a pequeños arroyos permanentes en las montañas de la Faja Volcánica Transmexicana; estas especies, además, se conforman por poblaciones pequeñas y aisladas, lo cual incrementa su vulnerabilidad. En este trabajo se analizan las amenazas potenciales para Ambystoma rivulare, A. altamirani y A. leorae, y con base en los criterios propuestos por la SEMARNAT y el Puntaje de Vulnerabilidad Ambiental desarrollado por Wilson y McCranie (2003), se argumenta que el estado de conservación de estas especies puede cambiarse a un nivel de mayor protección

Potential distribution and habitat connectivity of Crotalus triseriatus in Central Mexico

The dusky rattlesnake, Crotalus triseriatus, used to be very abundant in many parts of the highlands of central Mexico, but with the increasing human population and associated activities, the rattlesnake habitats and populations have suffered drastic reductions and fragmentation. At the moment, the most important habitat features, associated with the presence of C. triseriatus, the current potential distribution and the landscape connectivity amongst the populations of the State of Mexico and Mexico City, are unknown. Therefore, we used the maximum entropy modelling software (MAXENT) to analyse the current potential distribution and most important habitat features, associated with the presence of the species. The variables with the highest contribution to the model were: proportion of Abies forest, minimum temperature of coldest month, maximum temperature of the warmest month, proportion of Pinus forest and annual precipitation. Furthermore, we found connectivity corridors only within mountain chains. Our results highlight the necessity for conserving the patches of Abies forest and preserving the populations of C. triseriatus and the connectivity of the landscape

Present and future ecological niche modeling of garter snake species from the Trans-Mexican Volcanic Belt

Articulo producto parcial de tesis doctoralLand use and climate change are affecting the abundance and distribution of species. The Trans-Mexican Volcanic Belt (TMVB) is a very diverse region due to geological history, geographic position, and climate. It is also one of the most disturbed regions in Mexico. Reptiles are particularly sensitive to environmental changes due to their low dispersal capacity and thermal ecology. In this study, we define the important environmental variables (considering climate, topography, and land use) and potential distribution (present and future) of the five Thamnophis species present in TMVB. To do so, we used the maximum entropy modeling software (MAXENT). First, we modeled to select the most important variables to explain the distribution of each species, then we modeled again using only the most important variables and projected these models to the future considering a middle-moderate climate change scenario (rcp45), and land use and vegetation variables for the year 2050 (generated according to land use changes that occurred between years 2002 and 2011). Arid vegetation had an important negative effect on habitat suitability for all species, and minimum temperature of the coldest month was important for four of the five species. Thamnophis cyrtopsis was the species with the lowest tolerance to minimum temperatures. The maximum temperature of the warmest month was important for T. scalaris and T. cyrtopsis. Low percentages of agriculture were positive for T. eques and T. melanogaster but, at higher values, agriculture had a negative effect on habitat suitability for both species. Elevation was the most important variable to explain T. eques and T. melanogaster potential distribution while distance to Abies forests was the most important variable for T. scalaris and T. scaliger. All species had a high proportion of their potential distribution in the TMVB. However, according to our models, all Thamnophis species will experience reductions in their potential distribution in this region. T. scalaris will suffer the biggest reduction because this species is limited by high temperatures and will not be able to shift its distribution upward, as it is already present in the highest elevations of the TMVB.Universidad Autónoma del Estado de México: 4047/2016SF. CONACY

Genetic diversity and genetic structure of an endemic Mexican Dusky Rattlesnake (Crotalus triseriatus) in a highly modified agricultural landscape: implications for conservation

ArtículoIt is necessary to determine genetic diversity of fragmented populations in highly modified landscapes to understand how populations respond to land-use change. This information will help guide future conservation and management strategies. We conducted a population genetic study on an endemic Mexican Dusky Rattlesnake (Crotalus triseriatus) in a highly modified landscape near the Toluca metropolitan area, in order to provide crucial information for the conservation of this species. There was medium levels of genetic diversity, with a few alleles and genotypes. We identified three genetically differentiated clusters, likely as a result of different habitat cover type. We also found evidence of an ancestral genetic bottleneck and medium values of effective population size. Inbreeding coefficients were low and there was a moderate gene flow. Our results can be used as a basis for future research and C. triseriatus conservation efforts, particularly considering that the Trans-Mexican Volcanic Belt is heavily impacted by destructive land-use practices

Genetic variability and structure of an isolated population of Ambystoma altamirani, a mole salamander that lives in the mountains of one of the largest urban areas in the world

Amphibians are globally threatened by habitat loss and fragmentation; species within the order Ambystoma are not the exception, as there are 18 species of mole salamanders in México, of which 16 are endemic and all species are under some national or international status of protection. The mole salamander, Ambystoma altamirani is a microendemic species, which is distributed in central México, within the trans-Mexican volcanic belt, and is one of the most threatened species due to habitat destruction and the introduction of exotic species. Nine microsatellite markers were used to determine the genetic structure, genetic variability, effective population size, presence of bottlenecks and inbreeding coefficient of one population of A. altamirani to generate information which might help to protect and conserve this threatened species. We found two genetic subpopulations with significant level of genetic structure (FST = 0.005) and high levels of genetic variability (Ho = 0.883; He = 0.621); we also found a small population size (Ne = 8.8), the presence of historical (M = 0.486) and recent bottlenecks under IAM and TPM models, with a low, but significant coefficient of inbreeding (FIS = −0.451). This information will help us to raise conservation strategies of this microendemic mole salamander species

Subthreshold psychosis in 22q11.2 deletion syndrome: multisite naturalistic study

Nearly one-third of individuals with 22q11.2 deletion syndrome (22q11.2DS) develop a psychotic disorder during life, most of them by early adulthood. Importantly, a full-blown psychotic episode is usually preceded by subthreshold symptoms. In the current study, 760 participants (aged 6-55 years) with a confirmed hemizygous 22q11.2 microdeletion have been recruited through 10 medical sites worldwide, as part of an international research consortium. Of them, 692 were nonpsychotic and with complete measurement data. Subthreshold psychotic symptoms were assessed using the Structured Interview for Prodromal Syndromes (SIPS). Nearly one-third of participants met criteria for positive subthreshold psychotic symptoms (32.8%), less than 1% qualified for acute positive subthreshold symptoms, and almost a quarter met criteria for negative/disorganized subthreshold symptoms (21.7%). Adolescents and young adults (13-25 years) showed the highest rates of subthreshold psychotic symptoms. Additionally, higher rates of anxiety disorders and attention deficit/hyperactivity disorder (ADHD) were found among the study participants with subthreshold psychotic symptoms compared to those without. Full-scale IQ, verbal IQ, and global functioning (GAF) scores were negatively associated with participants' subthreshold psychotic symptoms. This study represents the most comprehensive analysis reported to date on subthreshold psychosis in 22q11.2DS. Novel findings include age-related changes in subthreshold psychotic symptoms and evidence that cognitive deficits are associated with subthreshold psychosis in this population. Future studies should longitudinally follow these symptoms to detect whether and how early identification and treatment of these manifestations can improve long-term outcomes in those that eventually develop a psychotic disorder

Genetic variability and structure of jaguar (Panthera onca) in Mexican zoos

ArtículoGenealogical records of animals (studbook) are created to avoid reproduction between closely related individuals, which could cause inbreeding, particularly for such endangered species as the Panthera onca (Linnaeus, 1758). Jaguar is the largest felid in the Americas and is considered an important ecological key species. In Mexico, wild jaguar populations have been significantly reduced in recent decades, and population decline typically accompany decreases in genetic variation. There is no current census of captive jaguars in Mexico, and zoos do not follow a standardized protocol in breeding programs based on genetic studies. Here, we emphasise the importance of maintaining an adequate level of genetic variation and propose the implementation of standardised studbooks for jaguars in Mexico, mainly to avoid inbreeding. In addition, achieving the aims of studbook registration would provide a population genetic characterisation that could serve as a basis for ex situ conservation programmes

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

Schizophrenia occurs in about one in four individuals with 22q11.2 deletion syndrome (22q11.2DS). The aim of this International Brain and Behavior 22q11.2DS Consortium (IBBC) study was to identify genetic factors that contribute to schizophrenia, in addition to the ~20-fold increased risk conveyed by the 22q11.2 deletion. Using whole-genome sequencing data from 519 unrelated individuals with 22q11.2DS, we conducted genome-wide comparisons of common and rare variants between those with schizophrenia and those with no psychotic disorder at age ≥25 years. Available microarray data enabled direct comparison of polygenic risk for schizophrenia between 22q11.2DS and independent population samples with no 22q11.2 deletion, with and without schizophrenia (total n = 35,182). Polygenic risk for schizophrenia within 22q11.2DS was significantly greater for those with schizophrenia (padj = 6.73 × 10−6). Novel reciprocal case–control comparisons between the 22q11.2DS and population-based cohorts showed that polygenic risk score was significantly greater in individuals with psychotic illness, regardless of the presence of the 22q11.2 deletion. Within the 22q11.2DS cohort, results of gene-set analyses showed some support for rare variants affecting synaptic genes. No common or rare variants within the 22q11.2 deletion region were significantly associated with schizophrenia. These findings suggest that in addition to the deletion conferring a greatly increased risk to schizophrenia, the risk is higher when the 22q11.2 deletion and common polygenic risk factors that contribute to schizophrenia in the general population are both present

Mi nombre es de leyenda: mi hogar es un bosque de agua: ajolote de montaña

El anfibio del género y especie Ambystoma altamirani, también llamado ajolote de montaña, nos narra de manera breve la leyenda de su nombre y, desde su perspectiva, proporciona datos generales sobre la especie, describiendo a detalle su hábitat, su labor como bioindicador de calidad en los cuerpos de agua, así como las amenazas que ponen en peligro. Todo esto con el objetivo de informar y hacer tomar conciencia al lector acerca de la relevancia de esta especie.   The amphibian of the genus and species Ambystoma altamirani, also called mountain salamander, briefly narrates the legend of its name and, from its perspective, provides general data on the species, describing in detail its habitat, its work as a bioindicator of quality in bodies of water, as well as the threats that endanger it. All this with the objective of informing and making the reader aware of the relevance of this species.   &nbsp

Ambystoma leorae (TAYLOR, 1943). New records, natural history notes and threat status

Ambystoma leorae (TAylOR, 1943), is endemic to the “Sierra Nevada” mountains of central México. its known distribution (Figs. 1A, 1B) is restricted to six locations within the protected area “iztaccihuatl Popocatepetl National Park” (iPNP). The salamander was originally described from the town of Rio Frio (TAylOR 1943); later it was recorded in three sites surrounding the area (vEgA-lóPEZ & AlvAREZ 1992; lE MOS-ESPiNAl et al. 1999), and in another two southern sites (lEMOS-ESPiNAl & AMAyA EliAS 1985; vEgA-lóPEZ & AlvAREZ 1992). These records are restricted to the upper tributaries of the Balsas River in the west of the iPNP, dispersed within an area of about 28 km x 0.65 km.Autonomous university of the State of Mexico (3530/2013MT