1,498 research outputs found
Competition Between Kondo Screening and Magnetism at the LaAlO/SrTiO Interface
We present a theory of magnetic and magneto-transport phenomena at
LaAlO/SrTiO interfaces, which as a central ingredient includes coupling
between the conduction bands and local magnetic moments originating from charge
traps at the interface. Tuning the itinerant electron density in the model
drives transitions between a heavy Fermi liquid phase with screened moments and
various magnetic states. The dependence of the magnetic phenomena on the
electron density or gate voltage stems from competing magnetic interactions
between the local moments and the different conduction bands. At low densities
only the lowest conduction band, composed of the orbitals of Ti, is
occupied. Its antiferromagnetic interaction with the local moments leads to
screening of the moments at a Kondo scale that increases with density. However,
above a critical density, measured in experiments to be , the and bands begin to populate. Their
ferromagnetic interaction with the local moments competes with the
antiferromagnetic interaction of the band leading to eventual
reduction of the Kondo scale with density. We explain the distinct magneto
transport regimes seen in experiments as manifestations of the magnetic phase
diagram computed from the model. We present new data showing a relation between
the anomalous Hall effect and the resistivity in the system. The data strongly
suggests that the concentration of local magnetic moments affecting the
transport in the system is much lower than the carrier density, in accord with
the theoretical model.Comment: 13 pages and 9 figure
On the Cosmic Evolution of Fe/Mg in QSO Absorption Line Systems
We investigate the variation of the ratio of the equivalent widths of the
FeII2600 line to the MgII2796,2803 doublet as a
function of redshift in a large sample of absorption lines drawn from the
JHU-SDSS Absorption Line Catalog. We find that despite large scatter, the
observed ratio shows a trend where the equivalent width ratio
decreases monotonically with
increasing redshift over the range . Selecting the
subset of absorbers where the signal-to-noise ratio of the MgII equivalent
width is 3 and modeling the equivalent width ratio
distribution as a gaussian, we find that the mean of the gaussian distribution
varies as . We discuss various possible
reasons for the trend. A monotonic trend in the Fe/Mg abundance ratio is
predicted by a simple model where the abundances of Mg and Fe in the absorbing
clouds are assumed to be the result of supernova ejecta and where the cosmic
evolution in the SNIa and core-collapse supernova rates is related to the
cosmic star-formation rate. If the trend in reflects the
evolution in the abundances, then it is consistent with the predictions of the
simple model.Comment: 10 pages, 4 figures, final version published in MNRA
Effect of well-width on the electro-optical properties of a quantum well
We record photoreflectance from Ge/GeSi modulation doped quantum wells
possessing V/cm perpendicular electric fields. Qualitatively very
different spectra are obtained from samples of well-width 100 \AA and 250 \AA.
Comparing the wavefunctions calculated from an \textbf{k.p}
theory, we find that while they remain confined in the narrower 100 \AA QW, the
electric field causes them to tunnel into the forbidden gap in the 250 \AA\
well. This implies that the samples should show a transition from the quantum
confined Franz-Keldysh effect to the bulk-like Franz-Keldysh effect. Close to
the band-edge where Franz-Keldysh effects are important, simulated
photoreflectance spectra reproduce the essential features of the experiment,
without any adjustable parameters.Comment: 8 pages, 8 figures. Submitted to Phys. Rev.
Quasi-equilibrium optical nonlinearities in spin-polarized GaAs
Semiconductor Bloch equations, which microscopically describe the dynamics of
a Coulomb interacting, spin-unpolarized electron-hole plasma, can be solved in
two limits: the coherent and the quasi-equilibrium regime. These equations have
been recently extended to include the spin degree of freedom, and used to
explain spin dynamics in the coherent regime. In the quasi-equilibrium limit,
one solves the Bethe-Salpeter equation in a two-band model to describe how
optical absorption is affected by Coulomb interactions within a
spin-unpolarized plasma of arbitrary density. In this work, we modified the
solution of the Bethe-Salpeter equation to include spin-polarization and light
holes in a three-band model, which allowed us to account for spin-polarized
versions of many-body effects in absorption. The calculated absorption
reproduced the spin-dependent, density-dependent and spectral trends observed
in bulk GaAs at room temperature, in a recent pump-probe experiment with
circularly polarized light. Hence our results may be useful in the microscopic
modelling of density-dependent optical nonlinearities in spin-polarized
semiconductors.Comment: 7 pages, 6 figure
Tbr1 instructs laminar patterning of retinal ganglion cell dendrites.
Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs). Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of each RGC type are restricted to specific sublaminae, limiting the interneuronal types that can innervate them. How such dendritic restriction arises is unclear. We show that the transcription factor Tbr1 is expressed by four mouse RGC types with dendrites in the outer IPL and is required for their laminar specification. Loss of Tbr1 results in elaboration of dendrites within the inner IPL, while misexpression in other cells retargets their neurites to the outer IPL. Two transmembrane molecules, Sorcs3 and Cdh8, act as effectors of the Tbr1-controlled lamination program. However, they are expressed in just one Tbr1+ RGC type, supporting a model in which a single transcription factor implements similar laminar choices in distinct cell types by recruiting partially non-overlapping effectors
An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior
Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when associated with an intermolecular interaction, this yields linear polymers of hyperstable serpin molecules, which accumulate at the site of synthesis. This is the basis of many pathologies termed the serpinopathies. We have previously identified a monoclonal antibody (mAb4B12) that, in single-chain form, blocks α1-Antitrypsin (α1-AT) polymerisation in cells. Here, we describe the structural basis for this activity. The mAb4B12 epitope was found to encompass residues Glu32, Glu39 and His43 on helix A and Leu306 on helix I. This is not a region typically associated with the serpin mechanism of conformational change, and correspondingly the epitope was present in all tested structural forms of the protein. Antibody binding rendered β-sheet A - on the opposite face of the molecule - more liable to adopt an 'open' state, mediated by changes distal to the breach region and proximal to helix F. The allosteric propagation of induced changes through the molecule was evidenced by an increased rate of peptide incorporation and destabilisation of a preformed serpin-enzyme complex following mAb4B12 binding. These data suggest that prematurely shifting the β-sheet A equilibrium towards the 'open' state out of sequence with other changes suppresses polymer formation. This work identifies a region potentially exploitable for a rational design of ligands that is able to dynamically influence α1-AT polymerisation
Local Electrostatic Imaging of Striped Domain Order in LaAlO3/SrTiO3
The emerging field of complex oxide interfaces is generically built on one of
the most celebrated substrates - strontium titanate (SrTiO3). This material
hosts a range of phenomena, including ferroelasticity, incipient
ferroelectricity, and most puzzlingly, contested giant piezoelectricity.
Although these properties may markedly influence the oxide interfaces,
especially on microscopic length scales, the lack of local probes capable of
studying such buried systems has left their effects largely unexplored. Here we
use a scanning charge detector - a nanotube single-electron transistor - to
noninvasively image the electrostatic landscape and local mechanical response
in the prototypical LaAlO3/SrTiO3 system with unprecedented sensitivity. Our
measurements reveal that on microscopic scales SrTiO3 exhibits large anomalous
piezoelectricity with curious spatial dependence. Through electrostatic imaging
we unravel the microscopic origin for this extrinsic piezoelectricity,
demonstrating its direct, quantitative connection to the motion of locally
ordered tetragonal domains under applied gate voltage. These domains create
striped potential modulations that can markedly influence the two-dimensional
electron system at the conducting interface. Our results have broad
implications to all complex oxide interfaces built on SrTiO3 and demonstrate
the importance of microscopic structure to the physics of electrons at the
LaAlO3/SrTiO3 interface.Comment: MH and JAS contributed equally to this work; supplementary
information include
A Physical Model for z~2 Dust Obscured Galaxies
We present a physical model for the origin of z~2 Dust-Obscured Galaxies
(DOGs), a class of high-redshift ULIRGs selected at 24 micron which are
particularly optically faint (24/R>1000). By combining N-body/SPH simulations
of high redshift galaxy evolution with 3D polychromatic dust radiative transfer
models, we find that luminous DOGs (with F24 > 0.3 mJy at z~2 are well-modeled
as extreme gas-rich mergers in massive (~5x10^12-10^13 Msun) halos, with
elevated star formation rates (~500-1000 Msun/yr) and/or significant AGN growth
(Mdot > 0.5 Msun/yr), whereas less luminous DOGs are more diverse in nature. At
final coalescence, merger-driven DOGs transition from being starburst dominated
to AGN dominated, evolving from a "bump" to a power-law shaped mid-IR (IRAC)
spectral energy distribution (SED). After the DOG phase, the galaxy settles
back to exhibiting a "bump" SED with bluer colors and lower star formation
rates. While canonically power-law galaxies are associated with being
AGN-dominated, we find that the power-law mid-IR SED can owe both to direct AGN
contribution, as well as to a heavily dust obscured stellar bump at times that
the galaxy is starburst dominated. Thus power-law galaxies can be either
starburst or AGN dominated. Less luminous DOGs can be well-represented either
by mergers, or by massive ($M_{\rm baryon} ~5x10^11 Msun) secularly evolving
gas-rich disc galaxies (with SFR > 50 Msun/yr). By utilising similar models as
those employed in the SMG formation study of Narayanan et al. (2010), we
investigate the connection between DOGs and SMGs. We find that the most heavily
star-forming merger driven DOGs can be selected as Submillimetre Galaxies
(SMGs), while both merger-driven and secularly evolving DOGs typically satisfy
the BzK selection criteria.Comment: Accepted by MNRAS; major changes include better description of
dependency on ISM specification and updated models allowing dust to evolve
with metallicity
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