190 research outputs found

    Low cost gaze estimation: knowledge-based solutions

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    Eye tracking technology in low resolution scenarios is not a completely solved issue to date. The possibility of using eye tracking in a mobile gadget is a challenging objective that would permit to spread this technology to non-explored fields. In this paper, a knowledge based approach is presented to solve gaze estimation in low resolution settings. The understanding of the high resolution paradigm permits to propose alternative models to solve gaze estimation. In this manner, three models are presented: a geometrical model, an interpolation model and a compound model, as solutions for gaze estimation for remote low resolution systems. Since this work considers head position essential to improve gaze accuracy, a method for head pose estimation is also proposed. The methods are validated in an optimal framework, I2Head database, which combines head and gaze data. The experimental validation of the models demonstrates their sensitivity to image processing inaccuracies, critical in the case of the geometrical model. Static and extreme movement scenarios are analyzed showing the higher robustness of compound and geometrical models in the presence of user's displacement. Accuracy values of about 3° have been obtained, increasing to values close to 5° in extreme displacement settings, results fully comparable with the state-of-the-art

    Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8

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    Neutrophil extracellular traps (NETs) are webs of extracellular nuclear DNA extruded by dying neutrophils infiltrating tissue. NETs constitute a defence mechanism to entrap and kill fungi and bacteria. Tumours induce the formation of NETs to the advantage of the malignancy via a variety of mechanisms shown in mouse models. Here, we investigated the presence of NETs in a variety of human solid tumours and their association with IL-8 (CXCL8) protein expression and CD8+ T-cell density in the tumour microenvironment. Multiplex immunofluorescence panels were developed to identify NETs in human cancer tissues by co-staining with the granulocyte marker CD15, the neutrophil marker myeloperoxidase and citrullinated histone H3 (H3Cit), as well as IL-8 protein and CD8+ T cells. Three ELISA methods to detect and quantify circulating NETs in serum were optimised and utilised. Whole tumour sections and tissue microarrays from patients with non-small cell lung cancer (NSCLC; n = 14), bladder cancer (n = 14), melanoma (n = 11), breast cancer (n = 31), colorectal cancer (n = 20) and mesothelioma (n = 61) were studied. Also, serum samples collected retrospectively from patients with metastatic melanoma (n = 12) and NSCLC (n = 34) were ELISA assayed to quantify circulating NETs and IL-8. NETs were detected in six different human cancer types with wide individual variation in terms of tissue density and distribution. At least in NSCLC, bladder cancer and metastatic melanoma, NET density positively correlated with IL-8 protein expression and inversely correlated with CD8+ T-cell densities. In a series of serum samples from melanoma and NSCLC patients, a positive correlation between circulating NETs and IL-8 was found. In conclusion, NETs are detectable in formalin-fixed human biopsy samples from solid tumours and in the circulation of cancer patients with a considerable degree of individual variation. NETs show a positive association with IL-8 and a trend towards a negative association with CD8+ tumour-infiltrating lymphocytes

    Statefinder diagnostic and www-w^{\prime} analysis for interacting polytropic gas dark energy model

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    The interacting polytropic gas dark energy model is investigated from the viewpoint of statefinder diagnostic tool and www-w^{\prime} analysis. The dependency of the statefinder parameters on the parameter of the model as well as the interaction parameter between dark matter and dark energy is calculated. We show that different values of the parameters of model and different values of interaction parameter result different evolutionary trajectories in srs-r and www-w^{\prime} planes. The polytropic gas model of dark energy mimics the standard Λ\LambdaCDM model at the early time.Comment: 17 pages, 4 figures, ijtp accepte

    Stable Isotope Biogeochemistry of Seabird Guano Fertilization: Results from Growth Chamber Studies with Maize (Zea Mays)

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    Stable isotope analysis is being utilized with increasing regularity to examine a wide range of issues (diet, habitat use, migration) in ecology, geology, archaeology, and related disciplines. A crucial component to these studies is a thorough understanding of the range and causes of baseline isotopic variation, which is relatively poorly understood for nitrogen (δ(15)N). Animal excrement is known to impact plant δ(15)N values, but the effects of seabird guano have not been systematically studied from an agricultural or horticultural standpoint.This paper presents isotopic (δ(13)C and δ(15)N) and vital data for maize (Zea mays) fertilized with Peruvian seabird guano under controlled conditions. The level of (15)N enrichment in fertilized plants is very large, with δ(15)N values ranging between 25.5 and 44.7‰ depending on the tissue and amount of fertilizer applied; comparatively, control plant δ(15)N values ranged between -0.3 and 5.7‰. Intraplant and temporal variability in δ(15)N values were large, particularly for the guano-fertilized plants, which can be attributed to changes in the availability of guano-derived N over time, and the reliance of stored vs. absorbed N. Plant δ(13)C values were not significantly impacted by guano fertilization. High concentrations of seabird guano inhibited maize germination and maize growth. Moreover, high levels of seabird guano greatly impacted the N metabolism of the plants, resulting in significantly higher tissue N content, particularly in the stalk.The results presented in this study demonstrate the very large impact of seabird guano on maize δ(15)N values. The use of seabird guano as a fertilizer can thus be traced using stable isotope analysis in food chemistry applications (certification of organic inputs). Furthermore, the fertilization of maize with seabird guano creates an isotopic signature very similar to a high-trophic level marine resource, which must be considered when interpreting isotopic data from archaeological material

    Evaluation of time domain electromagnetic fields radiated by constant velocity moving particles traveling along an arbitrarily shaped cross-section waveguide using frequency domain Green's functions

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    A technique for the accurate computation of the time domain electromagnetic fields radiated by a charged distribution traveling along an arbitrarily shaped waveguide region is presented. Based on the transformation (by means of the standard Fourier analysis) of the time-varying current density of the analyzed problem to the frequency domain, the resulting equivalent current is further convolved with the dyadic electric and magnetic Green's functions. Moreover, we show that only the evaluation of the transverse magnetic modes of the structure is required for the calculation of fields radiated by particles traveling in the axial direction. Finally, frequency domain electric and magnetic fields are transformed back to the time domain, just obtaining the total fields radiated by the charged distribution. Furthermore, we present a method for the computation of the wakefields of arbitrary cross-section uniform waveguides from the resulting field expressions. Several examples of charged particles moving in the axial direction of such waveguides are included.The authors would like to thank ESA/ESTEC for having cofunded this research activity through the Network Partnering Initiative program and through the project "Multipactor Analysis in Planar Transmission Lines" (contract 20841/08/NL/GLC). We also are grateful to the Spanish government and the local Council of Murcia for their support through the projects CICYT Ref. TEC2010-21520-C04-04 and SENECA Ref. 08833/PI/08, respectively.Jimenez Nogales, M.; Marini, S.; Gimeno Martinez, B.; Alvarez Melcon, A.; Quesada Pereira, FD.; Boria Esbert, VE.; Soto Pacheco, P.... (2012). Evaluation of time domain electromagnetic fields radiated by constant velocity moving particles traveling along an arbitrarily shaped cross-section waveguide using frequency domain Green's functions. Radio Science. 47(5):1-14. https://doi.org/10.1029/2012RS005008S114475Alvarez-Melcon, A., & Mosig, J. R. (2000). 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