Effect of graphene substrate on the SERS Spectra of Aromatic bifunctional molecules on metal nanoparticles

The design of molecular sensors plays a very important role within nanotechnology and especially in the development of different devices for biomedical applications. Biosensors can be classified according to various criteria such as the type of interaction established between the recognition element and the analyte or the type of signal detection from the analyte (transduction). When Raman spectroscopy is used as an optical transduction technique the variations in the Raman signal due to the physical or chemical interaction between the analyte and the recognition element has to be detected. Therefore any significant improvement in the amplification of the optical sensor signal represents a breakthrough in the design of molecular sensors. In this sense, Surface-Enhanced Raman Spectroscopy (SERS) involves an enormous enhancement of the Raman signal from a molecule in the vicinity of a metal surface. The main objective of this work is to evaluate the effect of a monolayer of graphene oxide (GO) on the distribution of metal nanoparticles (NPs) and on the global SERS enhancement of paminothiophenol (pATP) and 4-mercaptobenzoic acid (4MBA) adsorbed on this substrate. These aromatic bifunctional molecules are able to interact to metal NPs and also they offer the possibility to link with biomolecules. Additionally by decorating Au or Ag NPs on graphene sheets, a coupled EM effect caused by the aggregation of the NPs and strong electronic interactions between Au or Ag NPs and the graphene sheets are considered to be responsible for the significantly enhanced Raman signal of the analytes [1-2]. Since there are increasing needs for methods to conduct reproducible and sensitive Raman measurements, Grapheneenhanced Raman Scattering (GERS) is emerging as an important method [3].Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Inspección eléctrica y lumínica en la institución educativa Lestonnac

En el actual documento se mostraran los resultados obtenidos en la inspección eléctrica y lumínica realizada en la institución educativa Lestonnac, teniendo como base y guía el RETIE (Reglamento técnico de instalaciones eléctricas), el RETILAP (Reglamento técnico de iluminación y alumbrado público) y por último la NTC 2050 (Código eléctrico Colombiano). Al ultimar la inspección eléctrica se puede concluir que la Institución Educativa presenta grandes carencias tanto en la parte eléctrica como en la lumínica trayendo consecuencias a las personas que realizan sus actividades diarias en dicho lugar. Dichas carencias se clasificarán en no conformidades muy graves, no conformidades graves y no conformidades leves para poder determinar si las instalaciones de la institución son conformes o no conformes a las normas y reglamentos. Para la clasificación se cuenta con los instrumentos adecuados para obtener resultados confiables y a partir de ellos realizar el dictamen final de la inspección

Termination and Cost Analysis with COSTA and its User Interfaces

COSTA is a static analyzer for Java bytecode which is able to infer cost and termination information for large classes of programs. The analyzer takes as input a program and a resource of interest, in the form of a cost model, and aims at obtaining an upper bound on the execution cost with respect to the resource and at proving program termination. The costa system has reached a considerable degree of maturity in that (1) it includes state-of-the-art techniques for statically estimating the resource consumption and the termination behavior of programs, plus a number of specialized techniques which are required for achieving accurate results in the context of object-oriented programs, such as handling numeric fields in value analysis; (2) it provides several nontrivial notions of cost (resource consumption) including, in addition to the number of execution steps, the amount of memory allocated in the heap or the number of calls to some user-specified method; (3) it provides several user interfaces: a classical command line, a Web interface which allows experimenting remotely with the system without the need of installing it locally, and a recently developed Eclipse plugin which facilitates the usage of the analyzer, even during the development phase; (4) it can deal with both the Standard and Micro editions of Java. In the tool demonstration, we will show that costa is able to produce meaningful results for non-trivial programs, possibly using Java libraries. Such results can then be used in many applications, including program development, resource usage certification, program optimization, etc

From Object Fields to Local Variables: A Practical Approach to Field-Sensitive Analysis

Static analysis which takes into account the value of data stored in the heap is typically considered complex and computationally intractable in practice. Thus, most static analyzers do not keep track of object fields (or fields for short), i.e., they are field-insensitive. In this paper, we propose locality conditions for soundly converting fields into local variables. This way, field-insensitive analysis over the transformed program can infer information on the original fields. Our notion of locality is context-sensitive and can be applied both to numeric and reference fields. We propose then a polyvariant transformation which actually converts object fields meeting the locality condition into variables and which is able to generate multiple versions of code when this leads to increasing the amount of fields which satisfy the locality conditions. We have implemented our analysis within a termination analyzer for Java bytecode

Factores de riesgo asociados a enfermedades crónicas en pacientes mayores de 60 años en el Centro De Salud San Luis nivel i-3 en el periodo agosto a septiembre del 2021

El presente trabajo de investigación tuvo como objetivo general determinar los factores de riesgo asociados en enfermedades crónicas en pacientes mayores de 60 años en el Centro de Salud San Luis Nivel I-3 en el periodo 2021, por tanto, a nivel metodológico la investigación se desarrolla como uno retrospectivo, transversal, observacional, relacional, la muestra fue conformada por 189 pacientes y se utilizara como instrumento de recolecion de datos un ficha de registro. Los principales resultados revelan que los pacientes son del genero masculino en un 54%, entorno a la edad prevalencen los de 60 a 69 años en un 35% y el nivel de peso es obeso en un 37%. Se concluye que existe relación significativa entre la prevalencia de factores de riesgo y las enfermedades crónicas en pacientes mayores de 60 años con una significancia menor a 0,05 y se demostró que los factores de riesgo asociados a las enfermedades crónicas no transmisibles en pacientes mayores de 60 años en el Centro de Salud San Luis Nivel I-3 durante el periodo 2021 son los habitos de consumo y los factores metabólicos

Relación de relajantes musculares y su efecto sobre el bloqueo residual, en pacientes bajo anestesia general, Hospital Carlos Lanfranco La Hoz, durante febrero a junio del 2025

El presente trabajo de investigación determina la relación de relajantes musculares y su efecto sobre la parálisis residual, en pacientes bajo anestesia general en pacientes bajo anestesia general en el hospital Carlos Lanfranco La Hoz durante los meses de febrero a junio del 2025

Simulation Study of the Effect of Decreasing Truck Traffic Flow on Safety on Almeria-Barcelona Corridor

[EN] In this paper the effect of truck traffic on road safety has been analyzed through simulation study. The main objective of the study is to quantify the effect of the decreasing average annual daily traffic of heavy duty vehicles (trucks) on road safety. As the road safety indicators the frequency road accidents is considered. The data used in the study were collected from one of the most crowded routes in Spain which connects Almeria (south-east) with Barcelona (northeast). The observed data covers year 2010 and were classified into 2 road types: dual carriageways and toll roads. The estimation was carried out using negative binomial model and Markov Chain Monte Carlo simulation. Using the estimation results new traffic scenarios were proposed where the traffic flow is assumed to change its values. A total of 33 scenarios were proposed and new accidents data were generated through MCMC sampling. The comparison of the simulated and observed accident data shows that the effect of decreasing truck traffic flow could meliorate road safety in the route. The simulation tool could be applied to evaluate the effects of freight modal shift from road to rail.This work has been carried out in the framework of the MODALTRAM - TRA2011- 28647-C02-01 Research Project "Development of an integrated methodology for the assessment of effects on Safety and Environment, for the road and rail modal shift", of the Spanish National Research Plan 2011-2014, Ministry of Economy and Competitiveness (MINECO). The authors would also like to thanks the Community of Madrid, that contributed to this work through the SEGVAUTO-TRIES-CM (S2013-MIT2713) Programme.Dadashova, B.; Arenas Ramirez, B.; González Fernandez, C.; Aparicio Izquierdo, F. (2016). Simulation Study of the Effect of Decreasing Truck Traffic Flow on Safety on Almeria-Barcelona Corridor. En XII Congreso de ingeniería del transporte. 7, 8 y 9 de Junio, Valencia (España). Editorial Universitat Politècnica de València. 1649-1659. https://doi.org/10.4995/CIT2016.2016.4214OCS1649165

Control de inversor multinivel modular mmc monofásico de 500W a 120VRMS

Este trabajo de grado se centra en el diseño, elaboración y verificación de un inversor multinivel modular monofásico de 500w a 120 Vrms, debido a la necesidad de implementar un dispositivo para la conversión de energía eléctrica en el semillero de investigación SmartGrids & MicroGrids de la universidad Autónoma de Occidente. El objetivo principal fue implementar un control escalar sobre un convertidor MMC (Por sus siglas en inglés Modular Multilevel Converter) de nueve niveles monofásico partiendo de una fuente de DC. Se plantea una metodología clara para la implementación de dicho dispositivo totalmente funcional, bajo los criterios de diseño presentados posteriormente y normatividad IEEE 519-2014 que regula la distorsión armónica en el punto de conexión a la red.This degree work focused on the design, elaboration, and verification of a singlephase modular multilevel inverter of 500w at 120 Vrms, due to the need to implement a device for the conversion of electrical energy in the SmartGrids & MicroGrids research hotbed of the university. Autonomous of the West. The main objective was to implement a scalar control on a single-phase nine-level MMC converter starting from a DC source. A methodology with a qualitative and quantitative approach was proposed on the implementation of said device. Thus, obtaining a fully functional hardware under the design criteria presented later and IEEE 519-2014 regulations that regulate harmonic distortion at the point of connection to the network.Proyecto de grado (Ingeniero Electrónico y de Telecomunicaciones)-- Universidad Autónoma de Occidente, 2021PregradoIngeniero(a) en Electrónica y Telecomunicacione