Qualitative Measures of Equity in Small Groups

We investigate the utility of two qualitative measures of equity. Our data are videos of groups of first-generation and Deaf or hard-of-hearing students in a pre-matriculation university program designed to help them persist in STEM fields by developing their metacognitive practices. We analyze video data of students in small groups trying to accomplish various tasks. We analyze how groups engage with proposed ideas (inchargeness) and create a space of open sharing (civility). By capturing different aspects of each group, these measures combine to help our understanding of what an equitable group could look like.Comment: Accepted to International Conference of the Learning Sciences (ICLS) 201

Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells

Erythropoietin receptor (EpoR) has been reported to be overexpressed in tumours and has raised safety concerns regarding the use of erythropoiesis-stimulating agents (ESAs) to treat anaemia in cancer patients. To investigate the potential for EpoR to be overexpressed in tumours, we have evaluated human tumours for amplification of the EPOR locus, levels of EPOR transcripts, and expression of surface EpoR protein. Gene amplification analysis of 1083 solid tumours found that amplification of the EPOR locus was rare with frequencies similar to other non-oncogenes. EPOR transcript levels in tumours and tumour cell lines were low in comparison with bone marrow and were equivalent to, or lower than, levels in normal tissues of tumour origin. Although EpoR mRNA was detected in some tumour lines, no EpoR could be detected on the cell surface using 125I-Epo binding studies. This may be due to the lack of EpoR protein expression or lack of cell-surface-trafficking factors, such as Jak2. Taken together, we have found no evidence that EpoR is overexpressed in tumours or gets to the surface of tumour cells. This suggests that there is no selective advantage for tumours to overexpress EpoR and questions the functional relevance of EpoR gene transcription in tumours

Secondary analysis of teaching methods in introductory physics: A 50 k-student study

Citation: Von Korff, J., Archibeque, B., Gomez, K. A., Heckendorf, T., McKagan, S. B., Sayre, E. C., . . . Sorell, L. (2016). Secondary analysis of teaching methods in introductory physics: A 50 k-student study. American Journal of Physics, 84(12), 969-974. doi:10.1119/1.4964354Physics education researchers have developed many evidence-based instructional strategies to enhance conceptual learning of students in introductory physics courses. These strategies have historically been tested using assessments such as the Force Concept Inventory (FCI) and the Force and Motion Conceptual Evaluation (FMCE). We have performed a review and analysis of FCI and FMCE data published between 1995 and 2014. We confirm previous findings that interactive engagement teaching techniques are significantly more likely to produce high student learning gains than traditional lecture-based instruction. We also establish that interactive engagement instruction works in many settings, including those with students having a high and low level of prior knowledge, at liberal arts and research universities, and enrolled in both small and large classes. (C) 2016 Author(s)

The Influence of Oscillating Dietary Protein Concentrations on Finishing Cattle. II. Nutrient Retention and Ammonia Emissions

We hypothesized that oscillation of the dietary CP concentrations would improve efficiency of N use and reduce N loss to the environment. Charolais-cross steers (n = 8; 315 ± 21 kg of BW) were used in a replicated 4 × 4 Latin square design. The steers were allowed ad libitum access to the following diets: 1) 9.1% CP (low), 2) 11.8% CP (medium), 3) 13.9% CP (high), or 4) low and high oscillated on a 48-h interval on each diet (oscillating). Dry matter intake did not differ among treatments (P = 0.46), but N intake differed (P \u3c 0.01) from 94 (low) to 131 (medium), 142 (high), and 133 g/d (oscillating), as designed. Dry matter digestibility increased (P \u3c 0.01) from 71.8% (low) to 75.8% (medium), 77.7% (high), and 77.5% (oscillating). Nitrogen digestibility increased (P \u3c 0.01) from 62.2% (low) to 67.2% (medium) to 70.1% (high) and 70.9% (oscillating). Nitrogen retention was greater (P \u3c 0.01) in steers fed oscillating (55.0 g/d) than in the steers fed low (34.8 g/ d) or high (40.2 g/d), but N retention of steers fed medium (49.8 g/d) differed (P = 0.02) only from that of steers fed low. Urinary urea N did not differ between steers fed medium (19.5 g/d) or oscillating (21.3 g/d) but was lowest (P \u3c 0.01) for those fed low (8.2 g/d) and greatest for those fed high (39.2 g/d). Daily heat production (kcal/BW0.75) tended (P = 0.09) to be less for the steers fed low (177) than those fed medium (189), high (188), or oscillating (182). Cumulative in vitro ammonia volatilization from the manure of steers fed oscillating was lower (P \u3c 0.01) for the initial 5 d of incubation than from manure of those fed medium, but there was no difference after 11 d of incubation. Additionally, there was a decrease (P \u3c 0.01) in in vitro ammonia volatilization as protein concentration in the diet decreased from high to medium to low. These data indicate that oscillation of the dietary protein improved N retention of finishing steers compared with those in high and low N diets and that these changes were great enough to correspondingly alter ammonia volatilization from manure

Qualitative Measures of Equity in Small Groups

We investigate the utility of two qualitative measures of equity. Our data are videos of groups of first-generation and Deaf or hard-of-hearing students in a pre-matriculation university program designed to help them persist in STEM fields by developing their metacognitive practices. We analyze video data of students in small groups trying to accomplish various tasks. We analyze how groups engage with proposed ideas (inchargeness) and create a space of open sharing (civility). By capturing different aspects of each group, these measures combine to help our understanding of what an equitable group could look like

Improving the prediction of methane production and representation of rumen fermentation for finishing beef cattle within a mechanistic model

The purpose of this study was to evaluate prediction of methane emissions from finishing beef cattle using an extant mechanistic model with pH-independent or pH-dependent VFA stoichiometries, a recent stoichiometry adjustment for the use of monensin, and adaptation of the underlying model structure, to see if prediction improvements could be made for beef cattle. The database used for independent evaluation of methane predictions consisted of 74 animal means from 6 studies. For the ‘Bannink’ stoichiometries, pH-dependence of stoichiometry improved the RMSPE statistic (38.8 to 36.6%) but the CCC statistic was reduced (0.509 to 0.469). Inclusion of monensin in the stoichiometry improved both pH-independent and pH-dependent predictions. For the ‘Murphy’ stoichiometries, pH-dependence worsened the RMSPE (31.2 to 33.7%) as well as the CCC (0.611 to 0.465) statistic. Inclusion of monensin in the stoichiometry improved predictions with the pH-independent but not with the pH-dependent stoichiometry. Results indicate that although improvements have been made to the mechanistic model, further improvement in the representation of VFA stoichiometry, and likely the representation and prediction of pH and NDF digestibility, are required for more accurate prediction of methane emissions for finishing beef cattle. However, inclusion of an adjustment for monensin feeding generally lead to improved methane predictions