Projeto do sistema embarcado e dimensionamento do sistema de alimentação de um Mini-VANT para imageamento giroestabilizado no âmbito da chamada pública MCT / FINEP-CTAERO-VANT-01 / 2009

Monografia (graduação)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Elétrica, 2014.O Trabalho desenvolvido tem como principal objetivo o cálculo, o dimensionamento e o acoplamento dos componentes eletrônicos embarcados em uma aeronave do tipo VANT projetada e construida por alunos da Universidade de Brasília. Como resultado dessa análise espera-se obter uma estrutura leve e confiável, capaz de realizar voos de forma segura, e instrumentada ao nível de se poder ter uma comunicação remota ao vivo da terra para a aeronave e ser capaz de gravar e registrar o voo por meio de uma câmera. Quando do retorno da aeronave ao solo, após uma hora de voo, os sistemas embarcados devem permanecer em situação de uso novamente. O projeto tem como finalidade a concepção de uma aeronave comercializável e facilmente operada para a qual este trabalho deve funcionar como um guia prático para a montagem do sistema embarcado. __________________________________________________________________________ ABSTRACTThe work developed has as main goal the calculation, dimensioning and the coupling of electronic components embedded in aircraft type constructed an UAV and designed by students from the University of Brasilia. As a result of this analysis it is expected get a lightweight and reliable structure, able to perform flights safely, and instrumented at the level of being able to have a live remote communication with the field and be able to record the flight by a camera. When returning to the ground after one hour of flight, the aircraft and the embedded systems must remain in use situation again. The project aims to design an airplane easily operated and tradable for which this work should serve as a practical guide for assembling the embedded system

Functionalized multiwalled carbon nanotubes as ultrasound contrast agents

Ultrasonography is a fundamental diagnostic imaging tool in everyday clinical practice. Here, we are unique in describing the use of functionalized multiwalled carbon nanotubes (MWCNTs) as hyperechogenic material, suggesting their potential application as ultrasound contrast agents. Initially, we carried out a thorough investigation to assess the echogenic property of the nanotubes in vitro. We demonstrated their long-lasting ultrasound contrast properties. We also showed that ultrasound signal of functionalized MWCNTs is higher than graphene oxide, pristine MWCNTs, and functionalized single-walled CNTs. Qualitatively, the ultrasound signal of CNTs was equal to that of sulfur hexafluoride (SonoVue), a commercially available contrast agent. Then, we found that MWCNTs were highly echogenic in liver and heart through ex vivo experiments using pig as an animal model. In contrast to the majority of ultrasound contrast agents, we observed in a phantom bladder that the tubes can be visualized within a wide variety of frequencies (i.e., 5.5–10 MHz) and 12.5 MHz using tissue harmonic imaging modality. Finally, we demonstrated in vivo in the pig bladder that MWCNTs can be observed at low frequencies, which are appropriate for abdominal organs. Importantly, we did not report any toxicity of CNTs after 7 d from the injection by animal autopsy, organ histology and immunostaining, blood count, and chemical profile. Our results reveal the enormous potential of CNTs as ultrasound contrast agents, giving support for their future applications as theranostic nanoparticles, combining diagnostic and therapeutic modalities

Management research and the UN Sustainable Development Goals (SDGs): a bibliometric investigation and systematic review

This paper investigates the contribution provided by business and management scholars on SDGs debate. A bibliometric and systematic literature review method was employed and analysed in 266 articles published between 2012 and 2019. The results reveal the existence of four themes of research: technological innovation (cluster 1); firms’ contribution in developing countries (cluster 2); non-financial reporting (cluster 3) and education for SDGs (cluster 4). Main insights from the analysis of the papers are discussed and future research directions for the field are provided

Serum testosterone levels and breast cancer recurrence

AbstractProspective studies show that high serum levels of androgens and estrogens are associated with increased incidence of postmenopausal breast cancer. The aim of the present analysis was to study the prognostic value of serum testosterone, estradiol and related factors in postmenopausal breast cancer patients. One hundred and ten patients without clinical recurrence were included in the study. After 5.5 years of follow‐up, 31 patients developed distant metastasis (16), local relapse (4), or contralateral breast cancer (11). The risk of adverse events in relation to hormone level was examined by Cox' proportional hazard modeling, adjusting for hormone receptor status and stage at diagnosis. Body mass index and serum levels of testosterone, estradiol and glucose were significantly higher in patients who recurred than those who did not. The hazard ratios were 1.8 (95% CI = 0.5–6.3) for the middle and 7.2 (95% CI = 2.4–21.4) for the upper tertiles of baseline testosterone distribution. Other hormones had only minor influence on prognosis. High testosterone predicts breast cancer recurrence. Further studies are required to determine whether dietary or other medical intervention to reduce testosterone can reduce the recurrence of breast cancer

Maximal aerobic capacity exercise testing protocols for elderly individuals in the era of COVID-19

[no abstract available

Safety procedures for exercise testing in the scenario of COVID-19: a position statement of the Societ\ue0 Italiana Scienze Motorie e Sportive

Recent data on coronavirus disease 2019 (COVID-19) pandemic showed that the virus is mostly conveyed by respiratory droplets that are produced at high intensity especially when an infected subject coughs or sneezes. Therefore, elevated volume ventilations, usually reached during physical efforts and exercise, are a potential source of contamination. On the other hand, the lockdown period which has lasted for nearly 2 months and is actually involving several countries worldwide, obliged a large part of human population to sedentary behaviors, drastically reducing their physical activity level, and reducing their cardiopulmonary fitness. Therefore, cardiopulmonary exercise testing could be beneficial, so that a safe and well-weighted return to pre-lockdown active lifestyle can be efficiently planned. However, specific guidelines on exercise testing safety procedures in the era of COVID-19 are unavailable so far. This article is aimed to provide an overview of safety procedures for exercise testing during and after COVID-19 worldwide pandemic

INTEnsive care bundle with blood pressure reduction in acute cerebral hemorrhage trial (INTERACT3): study protocol for a pragmatic stepped-wedge cluster-randomized controlled trial

Background: Early intensive blood pressure (BP) lowering remains the most promising treatment for acute intracerebral hemorrhage (ICH), despite discordant results between clinical trials and potential variation in the treatment effects by approach to control BP. As the third in a series of clinical trials on this topic, the INTEnsive care bundle with blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT3) aims to determine the effectiveness of a goal-directed care bundle protocol of early physiological control (intensive BP lowering, glycemic control, and pyrexia treatment) and reversal of anticoagulation, in acute ICH. Methods: INTERACT3 is a pragmatic, international, multicenter, stepped-wedge (4 phases/3 steps), cluster-randomized controlled trial to determine the effectiveness of a multifaceted care package in adult (age ≥ 18 years) patients (target 8360) with acute ICH (< 6 h of onset) recruited from 110 hospitals (average of 19 consecutive patients per phase) in low- and middle-income countries. After a control phase, each hospital implements the intervention (intensive BP lowering, target systolic < 140 mmHg; glucose control, target 6.1–7.8 mmol/L and 7.8–10.0 mmol/L in those without and with diabetes mellitus, respectively; anti-pyrexia treatment to target body temperature ≤ 37.5 °C; and reversal of anticoagulation, target international normalized ratio < 1.5 within 1 h). Information will be obtained on demographic and baseline clinical characteristics, in-hospital management, and 7-day outcomes. Central trained blinded assessors will conduct telephone interviews to assess physical function and health-related quality of life at 6 months. The primary outcome is the modified Rankin scale (mRS) at 6 months analyzed using ordinal logistic regression. The sample size of 8360 subjects provides 90% power (α = 0.05) to detect a 5.6% absolute improvement (shift) in the primary outcome of the intervention versus control standard care, with various assumptions. Discussion: As the largest clinical trial in acute ICH, INTERACT3 is on schedule to provide an assessment of the effectiveness of a widely applicable goal-directed care bundle for a serious condition in which a clearly proven treatment has yet to be established. Trial registration: ClinicalTrials.gov NCT03209258. Registered on 1 July 2017. Chinese Trial Registry ChiCTR-IOC-17011787. Registered on 28 June 201

Wound Myiasis Caused by Sarcophaga (Liopygia) Argyrostoma

In Mediterranean countries, Sarcophaga (Liopygia) crassipalpis, Sarcophaga (L.) argyrostoma, and Sarcophaga (L.) cultellata share the same ecological niche and can be responsible of myiasis. In this study, the main morphological characters of a larva found in a hospitalized woman were described and illustrated by light and SEM microscopy and the features discussed. Then, a fragment within the mitochondrial encoded cytochrome c oxidase subunit I (coxI) gene of ~735 bp was amplified and sequenced. The molecular investigation was necessary to confirm the species Sarcophaga (Liopygia) argyrostoma (99% of identity). Our findings showed that morphological descriptions of larvae of three Mediterranean species of Liopygia available in several papers might not be clear enough to allow for comparison and correct identification. Until results of reliable comparative studies of larvae of all three species will be available, the use of molecular tools is crucial, to avoid misleading or incomplete identification, and in particular when a myiasis becomes a legal issue

Cristalização de superfície em vidro do sistema Li2O--ZrO2--SiO2--Al2O3

A cinética de crescimento da camada superficial cristalizada em um vidro de composição do sistema LZSA,11,7Li2O·12,6ZrO2·68,6SiO2·7,1Al2O3 (% massa), foi estudada. Para a produção do vidro, utilizou-se matérias-primas comerciais (Li2CO3, ZrSiO4, SiO2, Al2O3), as quais foram homogeneizadas e fundidas a 1550 °Cpor 120 min e então vazadas em molde metálico. Amostras do vidro obtido foram seccionadas e submetidas atratamentos térmicos em diferentes temperaturas (825--925 °C) e tempos (30--150 min) para formação e crescimentoda camada cristalina. Seções transversais das amostras tratadas termicamente foram lixadas e polidas,tal que imagens das camadas cristalizadas pudessem ser visualizadas e medidas por microscopia. Os resultadosmostraram que é possível obter vidros do sistema LZSA com camadas cristalizadas contendo principalmenteespodumênio-β e silicatos de zircônio e lítio, de espessuras entre 13 e 665 μm, as quais crescem comvelocidades entre 0,4 e 4,8 μm/min no intervalo de temperatura estudado