7,975 research outputs found
Global Imbalances and the Global Saving Glut – A Panel Data Assessment
Since the late 1990s there have been substantial changes in the current account balances of a number of economies, most notably a marked widening in the current account deficit of the United States and increased net lending by many developing nations to developed economies. This paper uses panel data to examine what may have contributed to changes in the current account positions of a wide sample of developing and developed economies. In particular, we aim to assess the ‘global saving glut’ hypothesis that financial crises have contributed to the current account surpluses in developing economies. Overall, we find some support for this argument; there is a significant role for financial crises as well as institutional factors in determining current account balances. However, the model captures the broad trends evident in international capital flows for only some of the major regions in our sample.current accounts; financial crises; capital flows
Application of Osteopathic Manipulative Medicine to Ameliorate Sepsis Induced Ileus
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The rationale for responsible supply chain management and stakeholder engagement
Purpose
Firms are increasingly resorting to responsible supply chain management as they align their economic success with socially-responsible initiatives in their value chain. This contribution suggests that there are opportunities for global corporations who are keen on integrating responsible practices into their business operations. It is in their interest to report about their responsible supply chain management, social performance and sustainable innovations to their stakeholders.
Design/methodology/approach
This review paper identifies future research avenues in the promising areas of responsible procurement and global supply chain management.
Findings
The corporations’ differentiated strategies as well as their proactive engagement in responsible supply chain management can lead them to achieve a competitive advantage in the long term. the low‐cost producers may be neglecting the marketplace stakeholders, including suppliers, distributors among others. Moreover, the smaller businesses’ could not be in a position to follow responsible procurement practices as they may lack the scarce resources to do so.
Originality/value
This paper raises awareness about the integration of socially responsible behaviours and sustainable practices in business operations. It contends that a responsible supply chain management necessitates an improved relationship with suppliers and distributors in the value chain. This stakeholder engagement with ultimately create value to the businesses themselves.peer-reviewe
Building Engineering Feasibility Study: Herreshoff Marine Museum
Our design team was supplied with a dozen architectural designs from the students of the Roger Williams University Architectural School. After discussing the strengths and weaknesses of each our team was able to narrow our choices down to one base design to conduct our feasibility and structural integrity analysis. Currently, the structural integrity of the proposed building addition has been examined by determining the wind and the snow loads, the green roof requirements, and the column and beam loads. The feasibility of the chosen design was assessed by researching Bristol zoning regulations and developing a path through the required zoning variances, which will help in the construction phase
Impact of an L5 magnetograph on nonpotential solar global magnetic field modeling
We present the first theoretical study to consider what improvement could be obtained in global nonpotential modeling of the solar corona if magnetograph data were available from the L5 Lagrange point, in addition to from the direction of Earth. To consider this, we first carry out a "reference Sun" simulation over two solar cycles. An important property of this simulation is that random bipole emergences are allowed across the entire solar surface at any given time (such as can occur on the Sun). Next we construct two "limited data" simulations, where bipoles are only included when they could be seen from (i) an Earth-based magnetograph and (ii) either Earth- or L5 based magnetographs. The improvement in reproducing the reference Sun simulation when an L5 view is available is quantified through considering global quantities in the limited data simulations. These include surface and polar flux, total magnetic energy, volume electric current, open flux and the number of flux ropes. Results show that when an L5 observational viewpoint is included, the accuracy of the global quantities in the limited data simulations can increase by 26-40%. This clearly shows that a magnetograph at the L5 point could significantly increase the accuracy of global nonpotential modeling and with this the accuracy of future space weather forecasts.Publisher PDFPeer reviewe
A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle.
BACKGROUND: Mitochondria are a vital component of eukaryotic cells and their dysfunction is implicated in a large number of metabolic, degenerative and age-related human diseases. The mechanism or these disorders can be difficult to elucidate due to the inherent complexity of mitochondrial metabolism. To understand how mitochondrial metabolic dysfunction contributes to these diseases, a metabolic model of a human heart mitochondrion was created. RESULTS: A new model of mitochondrial metabolism was built on the principle of metabolite availability using MitoMiner, a mitochondrial proteomics database, to evaluate the subcellular localisation of reactions that have evidence for mitochondrial localisation. Extensive curation and manual refinement was used to create a model called iAS253, containing 253 reactions, 245 metabolites and 89 transport steps across the inner mitochondrial membrane. To demonstrate the predictive abilities of the model, flux balance analysis was used to calculate metabolite fluxes under normal conditions and to simulate three metabolic disorders that affect the TCA cycle: fumarase deficiency, succinate dehydrogenase deficiency and α-ketoglutarate dehydrogenase deficiency. CONCLUSION: The results of simulations using the new model corresponded closely with phenotypic data under normal conditions and provided insight into the complicated and unintuitive phenotypes of the three disorders, including the effect of interventions that may be of therapeutic benefit, such as low glucose diets or amino acid supplements. The model offers the ability to investigate other mitochondrial disorders and can provide the framework for the integration of experimental data in future studies.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
'Epileptic', 'epileptic person' or 'person with epilepsy'? Bringing quantitative and qualitative evidence on the views of UK patients and carers to the terminology debate
Challenges in banking the rural poor: evidence from Kenya’s western province
Most people in rural Africa do not have bank accounts. Without a safe place to save up money, it may be very difficult for people to take advantage of high-return investments of many types. Likewise, without a safe place to keep an emergency cash buffer, vulnerability to shocks might be exacerbated. Recognising this, policymakers and international aid organisations have begun to devote attention to expanding access to financial services in developing countries, especially in rural areas where access continues to be extremely limited. However, in Dupas et al. (2012) we investigate whether increasing access is enough
Detailed modelling of a large sample of Herschel sources in the Lockman Hole: identification of cold dust and of lensing candidates through their anomalous SEDs
We have studied in detail a sample of 967 SPIRE sources with 5σ detections at 350 and 500 μm and associations with Spitzer-SWIRE 24 μm galaxies in the HerMES-Lockman survey area, fitting theirmid- and far-infrared, and submillimetre, spectral energy distributions (SEDs) in an automatic search with a set of six infrared templates. For almost 300 galaxies,we havemodelled their SEDs individually to ensure the physicality of the fits. We confirm the need for the new cool and cold cirrus templates, and also of the young starburst template, introduced in earlier work. We also identify 109 lensing candidates via their anomalous SEDs and provide a set of colour–redshift constraints which allow lensing candidates to be identified from combined Herschel and Spitzer data. The picture that emerges of the submillimetre galaxy population is complex, comprising ultraluminous and hyperluminous starbursts, lower luminosity galaxies dominated by interstellar dust emission, lensed galaxies and galaxies with surprisingly cold (10–13 K) dust. 11 per cent of 500 μm selected sources are lensing candidates. 70 per cent of the unlensed sources are ultraluminous infrared galaxies and 26 per cent are hyperluminous. 34 per cent are dominated by optically thin interstellar dust (‘cirrus’) emission, but most of these are due to cooler dust than is characteristic of our Galaxy. At the highest infrared luminosities we see SEDs dominated by M82, Arp 220 and young starburst types, in roughly equal proportions
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